In humans, the dominant allele N causes an abnormal shape of the patella in the knee (n is the normal allele). A separate gene affects finger length, and the dominant allele B causes abnormally short fingers, whereas b give normal length, A study focused on people who have both abnormal patellae and short (they most likely have the genotype N/n B/b). They inherited the N allele from one parent and the B allele from the other parent. These N/n B/b individuals mated with normal spouses. (The spouses had no history of abnormal patellae or short fingers in their families; they can be assumed to be homozygous normal.) 40 progeny were boom; they are classified as follows. Normal 3 Abnormal knees and fingers 2 Abnormal knees only 17 Abnormal fingers only 18 Using the chi square test, determine whether there is significant linkage between the B/b and the N/n gene. x^2 = P = linked? If you conclude there is linkage, what is the distance between the two genes? Solution Linked genes are the genes that present on same chromosome and transmit together to next generation. As seen in the question, in F2 individuals both the characters are segregated independently and no cross over is there. So there genes are not at all linked genes.