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Impact	
  of	
  HAIs	
  on	
  the	
  hospital	
                                                                                                                                                                       28-­‐02-­‐13	
  




                                                                                                   ¤ 	
  Are	
  common	
  

                                                                                                   ¤ 	
  Preven?on	
  should	
  be	
  integral	
  part	
  of	
  pa?ent	
  	
  	
  
                                                                                                       	
  care	
  
                     Andreas	
  Voss,	
  MD,	
  PhD	
                                              ¤ 	
  Morbidity	
  and	
  mortality	
  (clinical	
  burden)	
  
                   Professor	
  of	
  Infec?on	
  Control	
  
                          RUNMC	
  &	
  CWZ	
                                                      ¤ 	
  High	
  financial	
  impact	
  (economic	
  burden)	
  	
  
                    Nijmegen,	
  The	
  Netherlands	
                                                    ² On	
  hospital	
  services	
  	
  
                                                                                                         ² On	
  costs	
  of	
  na?onal	
  health	
  care	
  




                 ¤ Pa?ent	
  
                                                                                                       ¤ 	
  Measurement	
  is	
  difficult	
  
                     ² Addi?onal	
  diagnos?c	
  tests	
  and	
  treatment	
  
                     ² Extended	
  hospital	
  stay	
                                                 ¤ 	
  Financial	
  impact	
  varies	
  between	
  different	
  	
  
                     ² Temporary/permanent	
  disability	
  (death)	
                                     	
  healthcare-­‐se]ngs,	
  -­‐systems	
  and	
  countries	
  
                 ¤ Hospital	
                                                                         ¤ “High	
  costs”	
  repeatedly	
  demonstrated	
  
                     ² Decreased	
  produc?on	
  (beds	
  blocked)	
  
                                                                                                       ¤ 	
  Increased	
  awareness	
  with	
  regard	
  to	
  the	
  	
  
                     ² Claims	
  and	
  li?ga?on	
                                                        	
  importance	
  of	
  infec?on	
  control	
  	
  	
  
                     ² Reimbursement	
  too	
  low	
  or	
  excluded	
  (DRG,	
  NI-­‐MRSA)	
  
                     ² Reputa?on/image	
  damage	
  (decrease	
  referrals)	
  
                 ¤ Society	
                                                                          ¤ Added	
  value	
  of	
  individual	
  IC	
  components	
  “s<ll	
  
                     ² Loss	
  of	
  labor	
                                                              unknown”	
  




                                                                                                   ¤  The	
  es?mate	
  for	
  the	
  member	
  states	
  is	
  that	
  between	
  
                                                                                                      8%	
  en	
  12%	
  of	
  the	
  hospitalized	
  pa?ents	
  experience	
  
                                                                                                      unintended	
  complica?ons	
  

                                                                                                   ¤  On	
  average	
  1	
  in	
  20	
  hospital	
  pa?ents	
  will	
  develop	
  a	
  NI	
  


                                                                                                   ¤  In	
  the	
  EU:	
  	
  4.1	
  miljoen	
  pa?ënten	
  per	
  year	
  resul?ng	
  in	
  
                                                                                                      the	
  death	
  of	
  37	
  000	
  pa?ents	
  

                                                                                                        Technical	
  report	
  "Improving	
  pa?ent	
  safety	
  in	
  the	
  EU",	
  drabed	
  the	
  Europeam	
  
               "Improving	
  pa<ent	
  safety	
  in	
  the	
  EU”	
                                                   Commission,	
  published	
  in	
  2008	
  by	
  RAND	
  Corpora?on.	
  
              Rapport	
  for	
  the	
  European	
  Commission	
  	
  
                  Published	
  in	
  2008	
  by	
  RAND	
  Co.	
  




Andreas	
  Voss,	
  MD,	
  PhD	
                                                                                                                                                                                                  1	
  
Impact	
  of	
  HAIs	
  on	
  the	
  hospital	
                                                                                                                                                                                                                                                  28-­‐02-­‐13	
  




                                    1.66/1,000	
  inhab.	
                                      10.000	
  GBD/case	
   60	
  mil	
  


                                    8.75/1,000	
  inhab.	
                                      4300	
  CHF/case	
          8	
  mil	
  




                                                                                                                                           Wilcox	
  MH,	
  Dave	
  J.	
  The	
  cost	
  HAI	
  and	
  the	
  value	
  of	
  infec?on	
  control.	
  J	
  Hosp	
  Infect	
  2000;45:81-­‐4	
  




                 …	
  manda?ng	
  hospitals	
  to	
  publically	
  report	
  HAI	
  rates	
  and	
  a	
  	
  
                 	
  	
  	
  	
  federal	
  pay-­‐for-­‐performance	
  measure	
  that	
  will	
  no	
  longer	
  	
  	
  	
  	
  
                 	
  	
  	
  	
  allow	
  Medicare	
  to	
  pay	
  more	
  for	
  pa?ents	
  with	
  HAIs	
  
                 	
  
                 	
  
                 	
  




                                                                     =	
  

                                                                                                                                                 …	
  we	
  would	
  have	
  been	
  born	
  with	
  a	
  zipper	
  and	
  
                                                                                                                                                            spare	
  parts	
  using	
  a	
  “click-­‐system”	
  




Andreas	
  Voss,	
  MD,	
  PhD	
                                                                                                                                                                                                                                                                             2	
  
Impact	
  of	
  HAIs	
  on	
  the	
  hospital	
                                                                                                                                                 28-­‐02-­‐13	
  




                   ¤ 	
  Shame	
  &	
  guilt	
  
                       	
  	
  



                   ¤ 	
  Hepa??s,	
  HIV	
  
                   ¤ 	
  STD-­‐pathogens,	
  HPV,	
  …	
  
                   ¤ 	
  TB,	
  respiratory-­‐viruses	
  




              ¤ 	
  Teaching-­‐hospital	
                                                                               ¤ 	
  Start	
  in	
  the	
  ICU	
  with	
  8	
  cases	
  in	
  	
  
                                                                                                                             	
  December	
  2011	
  
              ¤ 	
  560	
  beds,	
  32000	
  admissions/yr,	
  24000	
  day-­‐	
                                             ² 	
  SDD	
  as	
  possible	
  reason	
  
                 	
  admissions/yr,	
  OPC	
  for	
  the	
  larger	
  region	
                                                ² 	
  most	
  pa?ents	
  from	
  2	
  internal	
  	
  
                                                                                                                                	
  medicine	
  units	
  (oncol	
  &	
  dialysis)	
  
              ¤ 	
  3km	
  away	
  from	
  UMC	
  
                                                                                                                         ¤ 	
  Screening	
  of	
  the	
  2	
  medical	
  units:	
  	
  
              ¤ 	
  Full	
  microbiology	
  and	
  ID	
  service	
  (3.3	
  be)	
                                           	
  	
  VRE	
  prevalence	
  25%	
  
              ¤ 	
  Infec?on	
  control	
  (2	
  x	
  0.5be	
  MD,	
  4.6	
  be	
  ICP)	
                               ¤ 	
  Prevalence	
  screening	
  hospital-­‐	
  
                                                                                                                             	
  wide:	
  4	
  other	
  units	
  with	
  high	
  	
  
              ¤ 	
  Regional	
  infec?on	
  control	
                                                                       	
  prevalence	
  of	
  VRE	
  




              ¤ 	
  Outbreak	
  management	
  team	
  (core)	
                                       ¤ 	
  Environment	
  has	
  to	
  be	
  free	
  of	
  VRE	
  
                     ² 	
  CEO,	
  head	
  IC,	
  chair	
  medical	
  staff,	
  coordina?ng	
  	
            ² 	
  problem	
  bed-­‐pans	
  (washers)	
  &	
  commodes	
  
                       	
  	
  unit	
  manager,	
  head	
  communica?on	
                             ¤ 	
  Handhygiene	
  needs	
  to	
  be	
  improved	
  
              ¤ 	
  Outbreak	
  management	
  team	
  (large)	
                                             ² 	
  rings,	
  watches,	
  long	
  sleeves	
  
                     ² 	
  Ini?ally	
  all	
  medical	
  and	
  nursing	
  heads	
  of	
             ¤ 	
  All	
  pa?ents	
  on	
  correct	
  cohort	
  (VRE+,	
  -­‐,	
  ?)	
  
                       implemented	
  units	
  (must)	
  and	
  other	
  units	
  (can),	
                   ² Flagging	
  of	
  pa?ents	
  in	
  HIS	
  
                       communica?on,	
  fascility	
  management	
                                     ¤ 	
  Contact	
  isola?on	
  procedures	
  correct	
  
                     ² 	
  Aber	
  3	
  months:	
  all	
  unit	
  managers	
  (n=22)	
                      ² “I	
  dont	
  know	
  how”	
  
                                                                                                      ¤ 	
  All	
  HCWs	
  trained	
  
                                                                                                             ² Up	
  to	
  70%	
  new	
  HCWs	
  on	
  some	
  units	
  




Andreas	
  Voss,	
  MD,	
  PhD	
                                                                                                                                                                            3	
  
Impact	
  of	
  HAIs	
  on	
  the	
  hospital	
                                                                                                 28-­‐02-­‐13	
  




              ¤ 	
  All	
  “5-­‐steps”	
  are	
  monitored	
  per	
  department	
  on	
  
                 a	
  weekly	
  base	
  
              ¤ 	
  Feedback	
  in	
  weekly	
  OMT	
  with	
  managers	
  
              ¤ 	
  Analysis	
  and	
  	
  squeezing	
  in	
  weekly	
  core	
  OMT	
  
              ¤ 	
  Monthy	
  rapport	
  to	
  na?onal	
  outbreak	
  group	
  
                     ² 	
  all	
  outbreaks	
  need	
  to	
  be	
  rapported	
  
                     ² 	
  several	
  stages	
  which	
  can	
  end	
  in	
  a	
  na?onal	
  team	
  	
  
                       	
  taking	
  over	
  outbreak	
  control	
  




                                                                                                             ¤ 	
  Roomservice	
  
                                                                                                             ¤ 	
  Roomservice-­‐plus	
  
                                                                                                             ¤ 	
  RN	
  
                                                                                                             ¤ 	
  Nursing	
  assitent	
  
                                                                                                             ¤ 	
  Cleaners	
  


                                                                                                                         Vacant	
  
                                                                                                                      Responsibility	
  !	
  




Andreas	
  Voss,	
  MD,	
  PhD	
                                                                                                                            4	
  
Impact	
  of	
  HAIs	
  on	
  the	
  hospital	
                                                                                                                                                28-­‐02-­‐13	
  




              ¤ 	
  Time	
                                                                                  ¤ 	
  Aber	
  2	
  x	
  prevalence	
  screening	
  (hospital	
  wide),	
  	
  
                     ² 	
  52	
  x	
  OMT	
  (x2	
  core	
  and	
  large)	
                                    	
  weekly	
  screening	
  of	
  pa?ents	
  in	
  6	
  units	
  
                          ² 	
  transfer	
  to	
  nurses	
  on	
  ward	
  
                    ² 	
  100	
  training	
  sessions	
  “contact	
  isola?on”	
  
                                                                                                                 ² 	
  using	
  in-­‐house	
  PCR	
  
                    ² 	
  Monthly	
  up-­‐date	
  at	
  medical	
  staff	
  and	
  nursing	
  staff	
  	
     ¤ 	
  Cultures	
  from	
  the	
  environment	
  (bed-­‐pans	
  and	
  	
  
                      	
  	
  mee?ng	
                                                                          	
  commodes,	
  if	
  visibly	
  soiled	
  at	
  audits)	
  
                    ² 	
  several	
  leters	
  to	
  thousands	
  of	
  pa?ents,	
  internal	
  	
  
                      	
  	
  and	
  external	
  communica?on,	
  calling	
  center	
                        ¤ 	
  Typing	
  of	
  VRE-­‐isolates	
  (AFLP,	
  MLST)	
  
              ¤ 	
  Produc?on	
  
                     ² 	
  reduced	
  by	
  approx.	
  20%	
  on	
  6	
  wards	
  
              ¤ 	
  Supplies	
  




              ¤ 	
  EUR	
  2.000.000	
  	
  
                     ² 	
  excluding	
  loss	
  in	
  produc?on	
  
                     ² 10%	
  is	
  covered	
  by	
  insurance	
  
                                                                                                                  June	
  25-­‐28,	
  2013	
  
              ¤ 	
  Probably	
  no	
  “image	
  damage”	
  
                                                                                                                 Geneva	
  Switzerland	
  
                     ² 	
  one	
  of	
  10	
  hospitals	
  with	
  VRE	
  problem	
  
                     ² 	
  open	
  communica?on,	
  na?onal	
  symposium	
  
                                                                                                                             	
  
                     ² 	
  98%	
  coloniza?on,	
  overall	
  5	
  clinical	
  infec?ons	
                                   	
  
                       including	
  2	
  BSI	
  à	
  all	
  successfully	
  treated	
  with	
                   www.icpic2013.com	
  
                       teicoplanin	
  (vanB)	
  




Andreas	
  Voss,	
  MD,	
  PhD	
                                                                                                                                                                           5	
  

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Impact of Healthcare-Associated Infections on Hospitals

  • 1. Impact  of  HAIs  on  the  hospital   28-­‐02-­‐13   ¤   Are  common   ¤   Preven?on  should  be  integral  part  of  pa?ent        care   Andreas  Voss,  MD,  PhD   ¤   Morbidity  and  mortality  (clinical  burden)   Professor  of  Infec?on  Control   RUNMC  &  CWZ   ¤   High  financial  impact  (economic  burden)     Nijmegen,  The  Netherlands   ² On  hospital  services     ² On  costs  of  na?onal  health  care   ¤ Pa?ent   ¤   Measurement  is  difficult   ² Addi?onal  diagnos?c  tests  and  treatment   ² Extended  hospital  stay   ¤   Financial  impact  varies  between  different     ² Temporary/permanent  disability  (death)    healthcare-­‐se]ngs,  -­‐systems  and  countries   ¤ Hospital   ¤ “High  costs”  repeatedly  demonstrated   ² Decreased  produc?on  (beds  blocked)   ¤   Increased  awareness  with  regard  to  the     ² Claims  and  li?ga?on    importance  of  infec?on  control       ² Reimbursement  too  low  or  excluded  (DRG,  NI-­‐MRSA)   ² Reputa?on/image  damage  (decrease  referrals)   ¤ Society   ¤ Added  value  of  individual  IC  components  “s<ll   ² Loss  of  labor   unknown”   ¤  The  es?mate  for  the  member  states  is  that  between   8%  en  12%  of  the  hospitalized  pa?ents  experience   unintended  complica?ons   ¤  On  average  1  in  20  hospital  pa?ents  will  develop  a  NI   ¤  In  the  EU:    4.1  miljoen  pa?ënten  per  year  resul?ng  in   the  death  of  37  000  pa?ents   Technical  report  "Improving  pa?ent  safety  in  the  EU",  drabed  the  Europeam   "Improving  pa<ent  safety  in  the  EU”   Commission,  published  in  2008  by  RAND  Corpora?on.   Rapport  for  the  European  Commission     Published  in  2008  by  RAND  Co.   Andreas  Voss,  MD,  PhD   1  
  • 2. Impact  of  HAIs  on  the  hospital   28-­‐02-­‐13   1.66/1,000  inhab.   10.000  GBD/case   60  mil   8.75/1,000  inhab.   4300  CHF/case   8  mil   Wilcox  MH,  Dave  J.  The  cost  HAI  and  the  value  of  infec?on  control.  J  Hosp  Infect  2000;45:81-­‐4   …  manda?ng  hospitals  to  publically  report  HAI  rates  and  a            federal  pay-­‐for-­‐performance  measure  that  will  no  longer                  allow  Medicare  to  pay  more  for  pa?ents  with  HAIs         =   …  we  would  have  been  born  with  a  zipper  and   spare  parts  using  a  “click-­‐system”   Andreas  Voss,  MD,  PhD   2  
  • 3. Impact  of  HAIs  on  the  hospital   28-­‐02-­‐13   ¤   Shame  &  guilt       ¤   Hepa??s,  HIV   ¤   STD-­‐pathogens,  HPV,  …   ¤   TB,  respiratory-­‐viruses   ¤   Teaching-­‐hospital   ¤   Start  in  the  ICU  with  8  cases  in      December  2011   ¤   560  beds,  32000  admissions/yr,  24000  day-­‐   ²   SDD  as  possible  reason    admissions/yr,  OPC  for  the  larger  region   ²   most  pa?ents  from  2  internal      medicine  units  (oncol  &  dialysis)   ¤   3km  away  from  UMC   ¤   Screening  of  the  2  medical  units:     ¤   Full  microbiology  and  ID  service  (3.3  be)      VRE  prevalence  25%   ¤   Infec?on  control  (2  x  0.5be  MD,  4.6  be  ICP)   ¤   Prevalence  screening  hospital-­‐    wide:  4  other  units  with  high     ¤   Regional  infec?on  control    prevalence  of  VRE   ¤   Outbreak  management  team  (core)   ¤   Environment  has  to  be  free  of  VRE   ²   CEO,  head  IC,  chair  medical  staff,  coordina?ng     ²   problem  bed-­‐pans  (washers)  &  commodes      unit  manager,  head  communica?on   ¤   Handhygiene  needs  to  be  improved   ¤   Outbreak  management  team  (large)   ²   rings,  watches,  long  sleeves   ²   Ini?ally  all  medical  and  nursing  heads  of   ¤   All  pa?ents  on  correct  cohort  (VRE+,  -­‐,  ?)   implemented  units  (must)  and  other  units  (can),   ² Flagging  of  pa?ents  in  HIS   communica?on,  fascility  management   ¤   Contact  isola?on  procedures  correct   ²   Aber  3  months:  all  unit  managers  (n=22)   ² “I  dont  know  how”   ¤   All  HCWs  trained   ² Up  to  70%  new  HCWs  on  some  units   Andreas  Voss,  MD,  PhD   3  
  • 4. Impact  of  HAIs  on  the  hospital   28-­‐02-­‐13   ¤   All  “5-­‐steps”  are  monitored  per  department  on   a  weekly  base   ¤   Feedback  in  weekly  OMT  with  managers   ¤   Analysis  and    squeezing  in  weekly  core  OMT   ¤   Monthy  rapport  to  na?onal  outbreak  group   ²   all  outbreaks  need  to  be  rapported   ²   several  stages  which  can  end  in  a  na?onal  team      taking  over  outbreak  control   ¤   Roomservice   ¤   Roomservice-­‐plus   ¤   RN   ¤   Nursing  assitent   ¤   Cleaners   Vacant   Responsibility  !   Andreas  Voss,  MD,  PhD   4  
  • 5. Impact  of  HAIs  on  the  hospital   28-­‐02-­‐13   ¤   Time   ¤   Aber  2  x  prevalence  screening  (hospital  wide),     ²   52  x  OMT  (x2  core  and  large)    weekly  screening  of  pa?ents  in  6  units   ²   transfer  to  nurses  on  ward   ²   100  training  sessions  “contact  isola?on”   ²   using  in-­‐house  PCR   ²   Monthly  up-­‐date  at  medical  staff  and  nursing  staff     ¤   Cultures  from  the  environment  (bed-­‐pans  and        mee?ng    commodes,  if  visibly  soiled  at  audits)   ²   several  leters  to  thousands  of  pa?ents,  internal        and  external  communica?on,  calling  center   ¤   Typing  of  VRE-­‐isolates  (AFLP,  MLST)   ¤   Produc?on   ²   reduced  by  approx.  20%  on  6  wards   ¤   Supplies   ¤   EUR  2.000.000     ²   excluding  loss  in  produc?on   ² 10%  is  covered  by  insurance   June  25-­‐28,  2013   ¤   Probably  no  “image  damage”   Geneva  Switzerland   ²   one  of  10  hospitals  with  VRE  problem   ²   open  communica?on,  na?onal  symposium     ²   98%  coloniza?on,  overall  5  clinical  infec?ons     including  2  BSI  à  all  successfully  treated  with   www.icpic2013.com   teicoplanin  (vanB)   Andreas  Voss,  MD,  PhD   5