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T-Lymphocytes Function, Development, Subpopulations
Activation of T-lymphocytes ,[object Object],[object Object]
Thymic education ,[object Object],[object Object],[object Object]
Downloaded from: StudentConsult (on 18 July 2006 08:13 AM) © 2005 Elsevier  Interaction TCR-polypeptide-HLA molecule
Development of lymphocytes in the thymus
The Fate of T-lymphocytes in the Thymus
 
Downloaded from: StudentConsult (on 18 July 2006 11:18 AM) © 2005 Elsevier  V, D and J genes involved in T- and B- cell receptor formation
Downloaded from: StudentConsult (on 18 July 2006 11:29 AM) © 2005 Elsevier  Activation and differentiation of  B -lymphocytes
Downloaded from: StudentConsult (on 20 July 2006 09:34 AM) © 2005 Elsevier  Activation and differentiation of T-lymphocytes
Subpopulations of T-lymphocytes ,[object Object],[object Object],[object Object]
Central role of T-lymphocytes in specific immune response From:  http://pathmicro.med.sc.edu/ APC T h cell B cell Tc cell NK Ag Ag Ag NK cell Cytokines Granulocyte Macrophage Cytokines Antigen-presenting cell
Subpopulations of T- lymphocytes (all are CD3+) ,[object Object],[object Object],[object Object],[object Object],[object Object]
Subpopulations of Th-lymphocytes ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Fun ctions of T-lymphocytes
Development of Th1 and Th2 cells
T h 1 lym phocytes ,[object Object],[object Object],[object Object],[object Object],[object Object]
Function of Th1 cells
T h 2 lymphocytes ,[object Object],[object Object],[object Object],[object Object],[object Object]
Th2-lymphocytes are essential for stimulation of B-lymphocytes
Cytotoxic T-lymfocytes ,[object Object],[object Object],[object Object],[object Object]
CD8 lym phocytes induce apoptosis of target cells
Types of regulatory T-lymphocytes Periphery From: Nature Immunology IL-10
T reg  lymphocytes ,[object Object],[object Object],[object Object],[object Object],[object Object]
TR-1 Lymphocytes ,[object Object],[object Object],[object Object],[object Object]
“ Supresor“ CD8+ lymphocytes (Ts) ,[object Object]
T- and B-cells antigen-speciphic receptors
 -T-lymphocytes ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Intraepitelial  T-lymphocytes ,[object Object],[object Object],[object Object],[object Object],[object Object]

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Immunology v t-ly