immunology topic

1. Dr Ashish Warghane PhD
Department of Life Sciences,
Mandsaur University,
Mandsaur, Madhya Pradesh,
India. Pin: 458 001
Mob: +91- 8956649071, 9359101533
Email: ashish.warghane@meu.edu.in
IMMUNOLOGICAL MEMORY

2. Immunological memory is the ability of the immune system to
quickly and specifically recognize an antigen that the body has
previously encountered and initiate a corresponding immune
response.
Generally these are secondary, tertiary and other subsequent
immune responses to the same antigen.
Immunological memory is responsible for the adaptive immune
system, special T and B cells — the so-called memory T and B cells.
Immunological memory is the basis of vaccination.
Immunological memory

3. Immunological memory occurs after a primary immune response
against the antigen.
Immunological memory is thus created by each individual, after a
previous initial exposure, to a potentially dangerous agent.
The course of secondary immune response is similar to primary
immune response.
After the memory B cell recognizes the antigen it presents the
peptide: MHC II complex to nearby effector T cells.
That leads to activation of these cells and rapid proliferation of cells.
After the primary immune response has disappeared the effector
cells of the immune response are eliminated.
Development of immunological memory

5. In addition to the formed antibodies in the body there remains a
small number of memory T and B cells that make up the cellular
component of the immunological memory.
They stay in the body in a resting state and at the second or next
encounter with the same antigen these cells are able to respond
immediately and eliminate the antigen. Memory cells have a long
life and last up to several decades in the body.
However, there remain antibodies previously created in the body
that represent the humoral component of immunological memory
and comprise an important defensive mechanism in subsequent
infections.