Ignite 2013 #06 Surprises Between Two Worlds by Marina Goldman

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IgniteAmherst 2013 presentation, "Surprises Between Two Worlds" by Marina Goldman, Registered Nurse and Social Medical Activist.

SUPRISES
BETWEEN
TWO WORLDS!
Marina Goldman
Social Medical Activist

Wednesday, March 6, 13

Surprises
Are Gifts

Wednesday, March 6, 13

Our Journey
Sierra Leone

Wednesday, March 6, 13

The Team
Int’l Surgical Health Initiative

Wednesday, March 6, 13

Newark to Kabala
Disparate Worlds

Wednesday, March 6, 13

Overwhelming Need
Limited Time & Resources

Wednesday, March 6, 13

Small Injury
Surprising Outcome

Wednesday, March 6, 13

Ouch!
Put a Farmer Back to Work

Wednesday, March 6, 13

Different lives
Different Conditions

Wednesday, March 6, 13

Pain Management
Spinal Anesthesia

Wednesday, March 6, 13

Making Due
In an Unpredictable World

Wednesday, March 6, 13

Finding Solutions
Ultimate Upcycling

Wednesday, March 6, 13

Untreatable
When there is no Medication

Wednesday, March 6, 13

Untreatable
Too Far Gone

Wednesday, March 6, 13

Untreatable
But Preventable

Wednesday, March 6, 13

Gratitude
No Expectations, Few Worries

Wednesday, March 6, 13

High Tech
Low Touch

Wednesday, March 6, 13

High Touch
Low Tech

Wednesday, March 6, 13

Special Thanks to
Vishnu Hoﬀ Photography
Ziad Sifri, MD, Charlie Khoury
Josh Goldman

Wednesday, March 6, 13

SUPRISES
BETWEEN
TWO WORLDS!
Marina Goldman
Social Medical Activist
ishiglobal.org

Wednesday, March 6, 13

RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0). CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.

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Ignite 2013 #06 Surprises Between Two Worlds by Marina Goldman

1. SUPRISES BETWEEN TWO WORLDS! Marina Goldman Social Medical Activist Wednesday, March 6, 13

2. Surprises Are Gifts Wednesday, March 6, 13

3. Our Journey Sierra Leone Wednesday, March 6, 13

4. The Team Int’l Surgical Health Initiative Wednesday, March 6, 13

5. Newark to Kabala Disparate Worlds Wednesday, March 6, 13

6. Overwhelming Need Limited Time & Resources Wednesday, March 6, 13

7. Wednesday, March 6, 13

8. Wednesday, March 6, 13

9. Small Injury Surprising Outcome Wednesday, March 6, 13

10. Ouch! Put a Farmer Back to Work Wednesday, March 6, 13

11. Different lives Different Conditions Wednesday, March 6, 13

12. Pain Management Spinal Anesthesia Wednesday, March 6, 13

13. Making Due In an Unpredictable World Wednesday, March 6, 13

14. Finding Solutions Ultimate Upcycling Wednesday, March 6, 13

15. Untreatable When there is no Medication Wednesday, March 6, 13

16. Untreatable Too Far Gone Wednesday, March 6, 13

17. Untreatable But Preventable Wednesday, March 6, 13

18. Gratitude No Expectations, Few Worries Wednesday, March 6, 13

19. High Tech Low Touch Wednesday, March 6, 13

20. High Touch Low Tech Wednesday, March 6, 13

21. Wednesday, March 6, 13

22. Special Thanks to Vishnu Hoﬀ Photography Ziad Sifri, MD, Charlie Khoury Josh Goldman Wednesday, March 6, 13

23. SUPRISES BETWEEN TWO WORLDS! Marina Goldman Social Medical Activist ishiglobal.org Wednesday, March 6, 13

Ignite 2013 #06 Surprises Between Two Worlds by Marina Goldman

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