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Team 10 - Team IGI Tech 
Lessons Learned 
Product: Laparoscopic image fusion box that works with 
a surgeon’s existing lap camera and ultrasound. 
Interview count (~11 a week) 
Total In person Video Chat Phone 
102 53 6 43 
$2B 
$1B 
$250M 
Total Available Market - Every operating room 
in the U.S. 
Served Available Market - Every OR 
equipped for minimally invasive surgery (MIS) 
Target - Thoracic Surgeons in the U.S.
IGI Technologies Team 
Principal Investigator 
Raj 
Shekhar, PhD 
Industry Expert 
Mark 
Chandler, MBA 
Entrepreneur 
William 
Plishker, PhD 
● Principal investigator within the 
Sheikh Zayed Institute for 
Pediatric Surgical Innovation 
● Focuses on clinically driven 
innovation 
● 15 years of experience as a 
serial innovator of medical and 
surgical imaging technologies 
● Two of his prior inventions have 
led to commercial products. 
● CEO of IGI Technologies 
● Builder and leader of 
startups, converting 
academic research into 
real-world products. 
● 3 Different Silicon Valley 
startups as an engineer 
and marketer 
● Mayfield Fellow 
● Early stage medical 
device investor 
● Expert in commercializing 
intellectual property (IP) 
● Founder of Upstream 
Partners 
● CEO of TAO Lifesciences
1st Business Canvas - what we thought
First Business Canvas - what we thought
So here’s what we did: 
Experiment: Talk to a wide variety of lap 
surgeons outside of home institution 
Insight: Very first interview, many lap surgeons 
do not have ultrasound, and do not want it.
We talked to surgeons - and learned we didn’t 
know them as well as we thought 
Surgeon Value Propositions Surgeon Pains/Gains 
Products/ 
services 
Overlay 
ultrasound 
on lap field 
of view 
Guidance 
of ablative 
tools 
Gain creators 
Get to target more reliably 
than standalone ultrasound 
Get to target faster than 
standalone ultrasound 
Find targets 
Pain relievers 
Single display 
Lower technical difficulty 
Reduce risk of complication 
Customer Job(s) 
Lap surgery -- 
ablation/resection 
Pre-procedure -- 
diagnose 
Post procedure patient 
monitoring 
Often no task for 
ultrasound 
Gains 
Belief in better patient care 
More confidence in complete 
treatment 
More lap target identification, 
less open surgeon 
Faster procedures 
Pains 
Mental correlation across 
two screens 
Unfamiliarity with 
ultrasound 
Steep learning curve 
Complication risk
We refined surgeons into customer 
segments… and value propositions 
Field High 
volume 
procedure 
core need currently 
uses lap 
ultrasound 
Does NOT 
use robot 
Urology partial neph See target and vessels (fast, sans 
radiologist, mobile) 
⇒ do more laps (vs. open) 
✔ 
Gynecology hysterec-tomies 
See the ureter 
⇒ fewer complications 
no, but can 
read it 
✔ 
Oncology liver 
resections/ 
ablations 
See the target with ablation needle critical 
sections 
⇒ fewer readmissions 
✔ ✔ 
Thoracic ? lesion location in collapsed lung 
⇒ less invasive (more laps, no hand 
port) 
no ✔
Business Canvas Iteration - CS Refinement
So here’s what we did next: 
Experiment: Talk to urologic surgeons (and 
oncologic, gynecologic, thoracic) 
Insight: Good feedback on MVP from 
urologists, but thoracic presented as an even 
more compelling opportunity.
We kept talking to surgeons - and found patterns in 
thoracic surgery 
Pains 
- Disorienting 
- Hour-long search 
“Would do anything to 
localize tumors minimally 
invasively”
We kept talking to surgeons - and found patterns in 
thoracic surgery 
Pains 
- Disorienting 
- Hour-long search 
“Would do anything to 
localize tumors minimally 
invasively” 
50-100 cases a year at academic hospitals 
⇒ $250M market opportunity
Customer segments - what we learned 
(# of people overall supporting) 
High volume 
procedure 
core need uses lap 
ultrasound 
Does NOT 
use robot 
Urology partial neph See target and vessels 
⇒ do more laps (vs. open) ✔ 
Gyn hysterectomies 
endometriosis? 
endomet surgery is sensitive to depth 
⇒ provide real-time depth (1mm 
accuracy) to prevent uterus 
punctures (2) 
no, and most 
(3) can’t 
justify port 
small but 
growing 
Oncology focus on 
ablations 
Losing cases to interv rads (9) 
⇒ tool nav in lap ablation is hard, we 
would track everything in one place 
✔ ✔ 
Thoracic VATS for 
primary lung 
lesions 
lesion location in collapsed lung 
⇒ less invasive (more laps, no hand 
port), easier workflow (no fiducials), 
organ sparing, find smaller nodules, 
⇒ no reliance on interv rad (12) 
no, but willing 
to learn (10) limited
Business Canvas - Thoracic Pivot
There were many other learnings... 
KP 
KA 
KR 
Luminary 
Surgeon 
(KOL) 
Ultrasound 
Company 
Lap camera 
company 
Training Curriculum 
Enhancement 
Lap Ultrasound 
Visualization Studies 
Integration 
Refinement 
Software 
Devels APIs OR Access 
CR - GET 
Conference 
Presentations 
Youtube 
Publications 
CS 
Society Courses 
Centers of 
Excellence 
Surgeon 
OR 
Mngr 
Value 
asmt 
App form & pres comm 
support 
Proforma Financials 
Admin 
council 
Tech 
assmnt 
committee 
Conference 
Presentations 
Youtube 
Publications 
VAC 
Society Courses 
Centers of 
Excellence 
App form & pres 
support 
Proforma 
Financials 
Interest 
Consideration 
Purchase 
Awareness 
Booth 
Installation at 
luminary 
sites/KOLs 
Keep 
Support 
Unbundle 
Track other tools 
Use other 
camera/ 
ultrasound 
Upsell 
Advanced Viz: 
Vessel seg 
Advanced Viz: 
3D recon 
Cross Sell 
Other surgeons 
(thoracic, 
urologic, 
oncology, gyn) 
Referrals 
Academic 
hospitals 
Main-stream 
hospitals 
US 
comps 
Co-sales 
IGI Tech 
surgns 
Tracking 
company 
OR 
Mngers 
equipme 
nt supply 
contract 
hospital 
profit, 
etc. 
disposab 
lmarkers 
profit, 
etc. 
disposable 
markers
… and we are in a better position than 
ever for commercialization 
Pivot: 
Away from urology to thoracic 
Customer Segments: 
Primary - Thoracic 
Secondary - Urology, Gynecology, Oncology 
U.S. Market Opportunity: 
$250 Million 
102 Interviews: 
55 Surgeons 
6 Radiologists 
10 Surgical support 
10 Hospital administrators 
5 Ultrasound company officials 
3 Robot company officials 
2 Tracking company officials 
4 Regulatory, reimbursement, IP specialists 
7 Misc 
Product: Thoracic surgeons find small-cell 
carcinoma lung nodules twice as fast without 
preoperative preparation. 
info@igitechnologies.com 
www.igitechnologies.com
1st Business Canvas - what we thought
Business Canvas Iteration - CS Refinement
Business Canvas - Thoracic Pivot
With respect to submitting an SBIR/STTR Phase II application, we are making the 
following decision (PICK ONE) 
● Go with a nominal pivot: The feasibility data generated in the Phase I 
grant provide the appropriate technical foundation for a Phase II 
application, AND we are largely targeting the customer segments that 
we had originally anticipated* 
● Go with a significant pivot: The feasibility data generated in the Phase I grant 
provide the appropriate technical foundation for a Phase II application, BUT 
we are targeting very different customer segments than we had originally 
anticipated 
● No Go: We do not have a product/market fit that supports the continuation of 
this project in its current form, and/or we have made substantial pivots to the 
business model that require us to obtain additional technical feasibility data 
that should more appropriately be pursued under a new Phase I grant (or 
other R&D grant) 
● No Go: We plan to continue pursuing this project, but we intend to finance this 
project through other non-federal sources (e.g., venture, strategic partner, etc) 
*we view our thoracic segment as a refinement of our existing plan, and pivot within the 
course 
Current 
Start 
IRL = 6 (soft) 
(we have mostly validated 4-6)

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IGI Technologies I-Corps@NIH 121014

  • 1. Team 10 - Team IGI Tech Lessons Learned Product: Laparoscopic image fusion box that works with a surgeon’s existing lap camera and ultrasound. Interview count (~11 a week) Total In person Video Chat Phone 102 53 6 43 $2B $1B $250M Total Available Market - Every operating room in the U.S. Served Available Market - Every OR equipped for minimally invasive surgery (MIS) Target - Thoracic Surgeons in the U.S.
  • 2. IGI Technologies Team Principal Investigator Raj Shekhar, PhD Industry Expert Mark Chandler, MBA Entrepreneur William Plishker, PhD ● Principal investigator within the Sheikh Zayed Institute for Pediatric Surgical Innovation ● Focuses on clinically driven innovation ● 15 years of experience as a serial innovator of medical and surgical imaging technologies ● Two of his prior inventions have led to commercial products. ● CEO of IGI Technologies ● Builder and leader of startups, converting academic research into real-world products. ● 3 Different Silicon Valley startups as an engineer and marketer ● Mayfield Fellow ● Early stage medical device investor ● Expert in commercializing intellectual property (IP) ● Founder of Upstream Partners ● CEO of TAO Lifesciences
  • 3. 1st Business Canvas - what we thought
  • 4. First Business Canvas - what we thought
  • 5. So here’s what we did: Experiment: Talk to a wide variety of lap surgeons outside of home institution Insight: Very first interview, many lap surgeons do not have ultrasound, and do not want it.
  • 6. We talked to surgeons - and learned we didn’t know them as well as we thought Surgeon Value Propositions Surgeon Pains/Gains Products/ services Overlay ultrasound on lap field of view Guidance of ablative tools Gain creators Get to target more reliably than standalone ultrasound Get to target faster than standalone ultrasound Find targets Pain relievers Single display Lower technical difficulty Reduce risk of complication Customer Job(s) Lap surgery -- ablation/resection Pre-procedure -- diagnose Post procedure patient monitoring Often no task for ultrasound Gains Belief in better patient care More confidence in complete treatment More lap target identification, less open surgeon Faster procedures Pains Mental correlation across two screens Unfamiliarity with ultrasound Steep learning curve Complication risk
  • 7. We refined surgeons into customer segments… and value propositions Field High volume procedure core need currently uses lap ultrasound Does NOT use robot Urology partial neph See target and vessels (fast, sans radiologist, mobile) ⇒ do more laps (vs. open) ✔ Gynecology hysterec-tomies See the ureter ⇒ fewer complications no, but can read it ✔ Oncology liver resections/ ablations See the target with ablation needle critical sections ⇒ fewer readmissions ✔ ✔ Thoracic ? lesion location in collapsed lung ⇒ less invasive (more laps, no hand port) no ✔
  • 8. Business Canvas Iteration - CS Refinement
  • 9. So here’s what we did next: Experiment: Talk to urologic surgeons (and oncologic, gynecologic, thoracic) Insight: Good feedback on MVP from urologists, but thoracic presented as an even more compelling opportunity.
  • 10. We kept talking to surgeons - and found patterns in thoracic surgery Pains - Disorienting - Hour-long search “Would do anything to localize tumors minimally invasively”
  • 11. We kept talking to surgeons - and found patterns in thoracic surgery Pains - Disorienting - Hour-long search “Would do anything to localize tumors minimally invasively” 50-100 cases a year at academic hospitals ⇒ $250M market opportunity
  • 12. Customer segments - what we learned (# of people overall supporting) High volume procedure core need uses lap ultrasound Does NOT use robot Urology partial neph See target and vessels ⇒ do more laps (vs. open) ✔ Gyn hysterectomies endometriosis? endomet surgery is sensitive to depth ⇒ provide real-time depth (1mm accuracy) to prevent uterus punctures (2) no, and most (3) can’t justify port small but growing Oncology focus on ablations Losing cases to interv rads (9) ⇒ tool nav in lap ablation is hard, we would track everything in one place ✔ ✔ Thoracic VATS for primary lung lesions lesion location in collapsed lung ⇒ less invasive (more laps, no hand port), easier workflow (no fiducials), organ sparing, find smaller nodules, ⇒ no reliance on interv rad (12) no, but willing to learn (10) limited
  • 13. Business Canvas - Thoracic Pivot
  • 14. There were many other learnings... KP KA KR Luminary Surgeon (KOL) Ultrasound Company Lap camera company Training Curriculum Enhancement Lap Ultrasound Visualization Studies Integration Refinement Software Devels APIs OR Access CR - GET Conference Presentations Youtube Publications CS Society Courses Centers of Excellence Surgeon OR Mngr Value asmt App form & pres comm support Proforma Financials Admin council Tech assmnt committee Conference Presentations Youtube Publications VAC Society Courses Centers of Excellence App form & pres support Proforma Financials Interest Consideration Purchase Awareness Booth Installation at luminary sites/KOLs Keep Support Unbundle Track other tools Use other camera/ ultrasound Upsell Advanced Viz: Vessel seg Advanced Viz: 3D recon Cross Sell Other surgeons (thoracic, urologic, oncology, gyn) Referrals Academic hospitals Main-stream hospitals US comps Co-sales IGI Tech surgns Tracking company OR Mngers equipme nt supply contract hospital profit, etc. disposab lmarkers profit, etc. disposable markers
  • 15. … and we are in a better position than ever for commercialization Pivot: Away from urology to thoracic Customer Segments: Primary - Thoracic Secondary - Urology, Gynecology, Oncology U.S. Market Opportunity: $250 Million 102 Interviews: 55 Surgeons 6 Radiologists 10 Surgical support 10 Hospital administrators 5 Ultrasound company officials 3 Robot company officials 2 Tracking company officials 4 Regulatory, reimbursement, IP specialists 7 Misc Product: Thoracic surgeons find small-cell carcinoma lung nodules twice as fast without preoperative preparation. info@igitechnologies.com www.igitechnologies.com
  • 16. 1st Business Canvas - what we thought
  • 17. Business Canvas Iteration - CS Refinement
  • 18. Business Canvas - Thoracic Pivot
  • 19. With respect to submitting an SBIR/STTR Phase II application, we are making the following decision (PICK ONE) ● Go with a nominal pivot: The feasibility data generated in the Phase I grant provide the appropriate technical foundation for a Phase II application, AND we are largely targeting the customer segments that we had originally anticipated* ● Go with a significant pivot: The feasibility data generated in the Phase I grant provide the appropriate technical foundation for a Phase II application, BUT we are targeting very different customer segments than we had originally anticipated ● No Go: We do not have a product/market fit that supports the continuation of this project in its current form, and/or we have made substantial pivots to the business model that require us to obtain additional technical feasibility data that should more appropriately be pursued under a new Phase I grant (or other R&D grant) ● No Go: We plan to continue pursuing this project, but we intend to finance this project through other non-federal sources (e.g., venture, strategic partner, etc) *we view our thoracic segment as a refinement of our existing plan, and pivot within the course Current Start IRL = 6 (soft) (we have mostly validated 4-6)