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Guillermo Umpierrez, M.D. Professor of Medicine Division of Endocrinology Emory University School of Medicine How do you write  a scientific manuscript?
Consultants Number of consultants 8 Years in practice 26 (11 - 50) Clinical/basic research Clinical: 7, basic: 1, both: 2 Number of publications 316 (41 – 1300) Number of peer-review papers 104 (41 – 250)
What do medical scientist write? ,[object Object],[object Object],[object Object],[object Object]
Before You Write ,[object Object],[object Object],[object Object],[object Object]
“ Instructions to authors” ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Choosing a Target Journal ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Authorship ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Manuscript Structure  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Title ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Abstract ,[object Object],[object Object],[object Object],[object Object],[object Object]
Abstract ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Introduction ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
The “Fundamental” Question “ Few clinical trials have focused on the optimal management of inpatient hyperglycemia in the non-critical setting.  Accordingly, we conducted this prospective, randomized study to compare the efficacy and safety of a basal/bolus insulin regimen to SSI in patients with T2DM admitted to general medicine wards.” Umpierrez et al, Diabetes Care 30:2181–2186, 2007
Material and Methods ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],Material and Methods
[object Object],[object Object],[object Object],[object Object],[object Object],Material and Methods
68 subjects with DKA  IV Glulisine insulin therapy until resolution of DKA Transition to SC glargine once daily and glulisine before meals Insulin Analogs (n= 34) Human Insulin (n= 34) IV regular insulin therapy until resolution of DKA Transition to SC NPH and regular insulin twice daily Insulin Analogs versus Human Insulin in the Treatment of Patients with DKA
Umpierrez et at, Diabetes Care 30:1699-1703, 2003 Study Protocol
Results ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Tables  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Umpierrez et al, Diabetes Care 27:1873-1878, 2004 Tables
Figures should stand alone for comprehension  Umpierrez et al, Diabetes Care 30:2181–2186, 2007
The importance of the abstract, figures and figure legends ,[object Object]
Discussion ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Discussion
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Discussion
Other Important Items ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
References ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Review Process Paper Submitted Initial Decision by Editor Confirmation of Receipt Rejection Decide to Review Assign Reviewers Reviews Completed Reject Accept Notification to Author Revise Accept Revise
Reasons for Rejection ,[object Object],[object Object],[object Object],[object Object],[object Object]
Replying to Reviewers ,[object Object],[object Object]
Additional Tips! ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Additional Tips! ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Additional Tips! ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Additional Tips! What additional recommendation(s) would you give to a busy clinician on how to write manuscripts?  Do not procrastinate – just do it
Acknowledgement Faculty: Nadine Kaslow, Ph.D. Bobby Khan, M.D., Ph.D. Jeff Lennox, M.D. Jeff Sands, M.D. Peter Wilson, M.D. Nanette Wenger, M.D. Thomas Ziegler, M.D.

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How To Write A Manuscript (2008)

  • 1. Guillermo Umpierrez, M.D. Professor of Medicine Division of Endocrinology Emory University School of Medicine How do you write a scientific manuscript?
  • 2. Consultants Number of consultants 8 Years in practice 26 (11 - 50) Clinical/basic research Clinical: 7, basic: 1, both: 2 Number of publications 316 (41 – 1300) Number of peer-review papers 104 (41 – 250)
  • 3.
  • 4.
  • 5.
  • 6.
  • 7.
  • 8.
  • 9.
  • 10.
  • 11.
  • 12.
  • 13. The “Fundamental” Question “ Few clinical trials have focused on the optimal management of inpatient hyperglycemia in the non-critical setting. Accordingly, we conducted this prospective, randomized study to compare the efficacy and safety of a basal/bolus insulin regimen to SSI in patients with T2DM admitted to general medicine wards.” Umpierrez et al, Diabetes Care 30:2181–2186, 2007
  • 14.
  • 15.
  • 16.
  • 17. 68 subjects with DKA IV Glulisine insulin therapy until resolution of DKA Transition to SC glargine once daily and glulisine before meals Insulin Analogs (n= 34) Human Insulin (n= 34) IV regular insulin therapy until resolution of DKA Transition to SC NPH and regular insulin twice daily Insulin Analogs versus Human Insulin in the Treatment of Patients with DKA
  • 18. Umpierrez et at, Diabetes Care 30:1699-1703, 2003 Study Protocol
  • 19.
  • 20.
  • 21. Umpierrez et al, Diabetes Care 27:1873-1878, 2004 Tables
  • 22. Figures should stand alone for comprehension Umpierrez et al, Diabetes Care 30:2181–2186, 2007
  • 23.
  • 24.
  • 25.
  • 26.
  • 27.
  • 28.
  • 29. Review Process Paper Submitted Initial Decision by Editor Confirmation of Receipt Rejection Decide to Review Assign Reviewers Reviews Completed Reject Accept Notification to Author Revise Accept Revise
  • 30.
  • 31.
  • 32.
  • 33.
  • 34.
  • 35. Additional Tips! What additional recommendation(s) would you give to a busy clinician on how to write manuscripts? Do not procrastinate – just do it
  • 36. Acknowledgement Faculty: Nadine Kaslow, Ph.D. Bobby Khan, M.D., Ph.D. Jeff Lennox, M.D. Jeff Sands, M.D. Peter Wilson, M.D. Nanette Wenger, M.D. Thomas Ziegler, M.D.