Hiv Tb Vaccines
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The slideshow describes the vaccination strategies for the dreadly diseases HIV and Tuberculosis with a basic introduction to both the diseases.
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2. Vaccinia virus has greater potential as an oncolytic virus because it produces a protein called B18R that allows it to evade type I interferon inhibition.
3. The study shows that vaccinia virus or B18R can boost the replication of RNA viruses like SFV and VSV in cancer cells by overcoming the antiviral effects of type I interferons. This dual viral therapy leads to enhanced oncolytic activity.
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This document summarizes research on producing yellow fever virus in Vero cells grown in serum-free medium. The researchers were able to obtain very high virus titers of 108 pfu/mL using the best conditions for cell propagation and viral infection in serum-free medium. Analysis showed no difference in antigenic properties between virus cultivated in serum-containing and serum-free medium. SDS-PAGE analysis confirmed a drastic reduction in protein content for yellow fever virus cultivated in serum-free medium. Developing a cell culture process for propagating yellow fever virus in serum-free Vero cells could be an important step towards producing a new inactivated yellow fever vaccine.
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UX, ethnography and possibilities: for Libraries, Museums and Archives
1) The document discusses how the University of York Library has used various user experience (UX) techniques like ethnographic observation and interviews to better understand user needs and behaviors.
2) Some changes implemented based on UX findings include installing hot water taps, changing hours, and adding blankets - aimed at improving the small details of user experience.
3) The presentation encourages other libraries, archives and museums to try incorporating UX techniques like behavioral mapping and cognitive interviews to inform design changes that enhance services for users.
Visual Design with Data
An immersive workshop at General Assembly, SF. I typically teach this workshop at General Assembly, San Francisco. To see a list of my upcoming classes, visit https://generalassemb.ly/instructors/seth-familian/4813
I also teach this workshop as a private lunch-and-learn or half-day immersive session for corporate clients. To learn more about pricing and availability, please contact me at http://familian1.com
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Hiv Tb Vaccines
- 1. HIV AND TB VACCINES: OBSTACLES MET AND PROGRESSES MADE
- 4. HIV discovery LUC MONTAGNIER BARRE SINOUSSI
- 6. HIV Lifecycle T Cell CD4
- 7. Course of HIV Infection
- 11. Antigen Presenting Cells *“First-line Defense” *Involved in capturing antigen *Display ‘foreign’ antigens to activate T Cells T Cells *Involved in the ‘killing’ of virus-infected cells * Adaptive Immunity B Cells *Involved in making antibodies * Adaptive Immunity
- 12. The Ideal Vaccine Neutralising Antibody T cell Immunity Mucosal Immunity Innate Immunity
- 15. Strains / Clades Clades differ by around 20% of RNA and Protein sequence C C C E B B B A , D E C C C B B B 2 A-H O, N B
- 16. What are the steps in Vaccine development? Phase I: 10-30 volunteers, 8-12 months Phase II: 50-500 volunteers,18-24 months Phase III: Thousands of volunteers, 3 or more years
- 17. What types of HIV vaccines are being tested? Peptide epitopes (protein fragments) Live attenuated HIV Whole, killed HIV Naked DNA
- 18. Types of HIV vaccines Recombinant Viral Proteins Live bacterial vectors Live Viral Vectors Pseudovirions
- 19. HIV vaccines in clinical trials for efficacy and immunogenicity
- 22. WORLD TB CASES CASES OF TB PER 100,000 CITIZENS: >300 200-300 <50 100-200 N/A 50-100
- 23. THE FORERUNNERS ROBERT KOCH ALBERT CALMETTE CAMILLE GUERIN
- 24. The Bug
- 25. TUBERCULOSIS