Here are 20 drugs which cause kidney injury.docx REVIEW ARTICLES FOR B PHARM, M PHARM

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Here are 20 drugs that harm kidneys
Table:
S. No Title Years Remarks
01
Acute Renal Impairment in Patients
Due to Paracetamol Overdose in the
Absence of Hepatic Impairmen
2021 Paracetamol poisoning is mainly
associated with hepatotoxicity, and its
association with renal impairment is
rare.
02
Paracetamol-induced acute kidney
injury in the absence of acute liver
injury
2022 Clinically relevant acute kidney injury
due to paracetamol overdose alone is
extremely rare in the absence of
concomitant liver injury when
excluding other prerenal, renal, and
post renal causes of renal dysfunction,
NAC interference and chronic kidney
injury.
03 Diuretics(furosemide) in Acute
Kidney Injury
2022 The clearance of furosemide is delayed
in patients with AKI; however,
torsemide and bumetanide are
metabolized in the liver and their half-
lives are not prolonged in AKI
04
Increased risk of acute kidney
injury in coronavirus disease
patients with renin–angiotensin–
aldosterone-system blockade use: a
systematic review and meta-
analysis
2021 ACEIs and ARBs are widely used
antihypertensive medications, and their
use is most prevalent in the elderly and
chronic kidney disease patients, who
belong to the highest risk groups for
the development of COVID-19-related
mortalities and multiorgan failure
05
The Impact of Angiotensin-
Converting Enzyme Inhibitors or
Angiotensin II Receptor (losartan)
Blockers on Clinical Outcomes of
Acute Kidney Disease Patients
2021 angiotensin-converting enzyme
inhibitor, angiotensin II receptor
blocker, acute kidney disease, RAAS,
chronic kidney disease, post-AKI care,
dialysis, outcome

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06 Stopping versus continuing renin–
angiotensin–system inhibitors after
acute kidney injury and adverse
clinical outcomes: an observational
study from routine care data
2022 Stopping RASi use among survivors of
moderate-to-severe AKI was associated
with a similar risk of recurrent AKI,
but higher risk of the composite of
death, MI and stroke.
07 Aminoglycosides use has a risk of
acute kidney injury in patients
without prior chronic kidney
disease
2022 The outcome of acute kidney injury
(AKI) as a result of aminoglycosides
(AGs) use remains uncertain in patients
without prior chronic kidney disease
(CKD)
08 Dosing of Aminoglycosides in
Chronic Kidney Disease and End-
Stage Renal Disease Patients
Treated with Intermittent
Hemodialysis
2022 AG dosing recommendations for
patients with abnormal kidney
functions, especially for ESRD patients
treated via iHD. AGs evince a T1/2 of
approximately 2–3 days in these
patients, and during HD sessions,
approximately 50% of the drug is
removed from the body
09 Acetaminophen use and risk of
renal impairment: A systematic
review and meta-analysis
2020 Acetaminophen is associated with a
significantly increased risk of newly
developing renal impairment in adults.
Physicians who prescribe
acetaminophen should be aware of
potential adverse renal effects
10
Acetaminophen as Reno protective
Treatment in a Patient with Severe
kidney
2023 The demonstrated recovery in renal
function, with only a transient,
moderate increase in
aminotransferases, supports the value
of adjunctive acetaminophen as a Reno
protective treatment in severe malaria.
11
Nephrotoxicity of Ciprofloxacin
2019 Drug-induced nephrotoxicity is one
of the leading causes of acute kidney
injury worldwide. Nephrotoxicity of
ciprofloxacin is often underestimated.
In addition to causing acute kidney
injury, chronic drug toxicity can in
some cases lead to chronic kidney
disease and eventually end-stage
renal disease. Thus, the prevention of
ciprofloxacin nephrotoxicity should
be at the forefront of the approaches
employed to counteract drug-induced
kidney failure.

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12 Association of Higher-Dose Fluor
quinolone Therapy with Serious
Adverse Events in Older Adults
with Advanced Chronic Kidney
Disease
2022 These findings suggest that older
patients with advanced CKD who were
prescribed fluoroquinolones at higher
than recommended doses were more
likely to experience the overall
outcome of hospital admission with
neurological and/or psychiatric
disorders, hypoglycemia, or congestive
heart failure. There was a high
probability of. There was a possibility.
13 Treatment of Iron Deficiency
Anemia in CKD and End-Stage
Kidney Disease
2021 Those who require kidney replacement
therapy, which requires I.V. Iron is an
essential tool in the management of
iron deficiency anemia
14 The Impact of Iron
Supplementation for Treating
Anemia in Patients with Chronic
Kidney Disease: Results from
Pairwise and Network Meta-
Analyses of Randomized
Controlled Trial
2021 Our findings lead to an individualized
treatment approach of IDA in CKD
patients. Despite concerns regarding IV
iron supplementation, some are more
potent (e.g., ferumoxytol, ferric
carboxymaltose)
15 A systemic review and meta-
analysis on the efficacy and safety
of ferumoxytol for anemia in
chronic kidney disease patients
2022 This meta-analysis provides
preliminary evidence that ferumoxytol
use exerts beneficial effects on the
overall hematological outcomes in
patients with chronic kidney disease.
This study also reports improved
treatment related safety profile for
ferumoxytol when compared with
conventional iron formulations. The
findings from this study can have direct
implications in forming best practice
guidelines for managing anemia in
patients with chronic kidney disease.
16
Herbal Nephropathy (Cranberry)
2019 Finally, case reports have emerged,
mainly from the east, of massive
intravascular hemolysis and acute renal
failure after ingestion of herbal henna
(Lawsonia inermis). The etiology of
this has been attributed to G6PD
enzyme deficiency

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17
Editorial: Applications of Herbal
Medicine to Control Chronic
Kidney Disease
2021 These studies improve our
understanding on the mechanisms of
herbal medicine in treating CKD and
its related diseases. Potential
therapeutic targets are also proposed
for the prevention and treatment of
CKD
18 β-Lactam Dosing in Critical
Patients: A Narrative Review
of Optimal Efficacy and the
Prevention of Resistance and
Toxicity(●Penicillins
●Cephalosporins
●Cephamycins
●Carbapenems)
2022 Overall, β-lactams are frequently
considered safe, with negligible side
effects, but data have been gathered
that link this antibiotic class with
potentially severe side effects, mostly
dose-dependent
19 Renal manifestations of
recreational drugs: A narrative
review of the literature
2022 Based on this review, there is still a
paucity of data in the literature due to
under-reporting of cases, inherent
problems in finding causal association
between a particular drug and the
development of a single renal disease,
as in most cases, they do not exist as a
specific or separate entity, and there is
concomitant use of several drugs (with
or without adulterants and potentiating
factors) at the same time.
20 Chronic kidney disease and HIV in
the era of antiretroviral (Tenofovir
disoprovil fumarate) treatment
2019 Our findings do not confirm the high
risk of CKD reported in previous
studies of West Africans with HIV, but
support the recommendations for early
initiation of ART and close kidney
function monitoring in patients with
HBP or aged ≥40 yr.