SlideShare a Scribd company logo
Prateek Singh, CEO
Human biology replicated reliably
science@finnadvance.com
High cost and inefficient drug
development
Total cost: $2.6 billion
5k – 10 k
compounds
100 – 500
compounds
50 – 250
compounds
3-5
compounds
1
compound
HUMAN
5+ years 10+ years 12+ years
Prateek Singh, CEO
science@finnadvance.com
In-development Drugs Fail
in Clinical Trials
HUMAN
Drugs have different effects on 2D cell cultures and animals vs humans
→90 % of drugs validated on animals fail during human clinical trials
→Cell models and animal models do not adequately represent the human biology
→A large part of the total pharma R&D budget is spent on the failing drugs
Prateek Singh, CEO
science@finnadvance.com
Organ-on-Chip models allow significant saving in dollars (HUNDREDS OF MILLIONS) and
major timelines (YEARS)
Lancet. 2011 Jun
4;377(9781):1915
Impact of Finnadvance’s technology
In 5 years drug discovery costs are estimated to decrease 10-26% as a result
of this technology.
“If organ on chip was capable of identifying appropriate biomarkers, it would be
the “Holy Grail” of biotechnology”
Prateek Singh, CEO
science@finnadvance.com
Rare disease:
blood vessel
malformation
Patient-derived
cells
Our biomimetic
platform
Human disease-on-chip
Vascular anomaly organ-on-chip model
Prateek Singh, CEO
science@finnadvance.com
Organ-on-chip Market Forecast
2015 2020
Timescale (year)
2025
100B
10B
1B
100M
10M
MarketSize,Log.Scale
(USD)
Animal Research
In Vitro
3D In Vitro
Organ on a Chip
Prateek Singh, CEO
science@finnadvance.com
Ref : https://www.alliedmarketresearch.com/organ-on-chip-market
Ref : Organs on Chips 2017 report, March 2017, Yole Developpement
-M.Sc. Protein Tech and
Biochemistry, University of Oulu.
-B.Tech Biotechnology, National
institute of technology, India.
-5 peer reviewed publications.
-22 international presentations.
Prateek was born in India, and
after living in several countries
found a home in the scientific community of Oulu,
Northern Finland.
Prateek’s multi-disciplinary know-how was needed for
an EU Project aiming to uncover core mechanisms of
initiation and maintenance of Vascular Anomalies. The
study would be done on the Organ-on-Chip platforms
he would build. He founded Finnadvance to
commercialize this innovation and make drug discovery
faster and cheaper, while eliminating the use of
laboratory animals.
Prateek is a huge fan of science. He is extremely proud
of having worked on projects funded by NASA, ESA,
the Academy of Finland and TEKES.
Prateek Singh
CEO & Founder
Jari Moilanen
COOMinna Kihlström
CSO
Tuan Nguyen
CTO
Tuomas Nurmi
CMO
Highly Skilled & Diverse Team
Prateek Singh, CEO
science@finnadvance.com
-Ph.D. Vascular Biology, Uni. of Oulu
-M.Sc. Biochemistry and Cell Biology,
Oulu University.
-M.Sc. Thesis: Institute for Cancer
Research, University of Oslo, Norway.
-3 High-impact peer reviewed
publications. 3 Supervised Thesises.
Minna brings 8+ years cell culture and in
vitro research, 6+ years in vivo mouse
modelling and 7+ years microscopy
experience to the team.
-B.Eng & M.Sc in Biomedical Engineering
International University, Vietnam.
-Microtechnology research trainee,
University of Sheffield, UK.
-Ph.D. Studies in Biochemistry and
Molecular medicine, University of Oulu.
-2 Peer reviewed publications, 4
international presentations.
Tuan is a Biochemical Engineer who raised 2
research funding before finishing his M.Sc.
He has also won 2 young entrepreneur
competitions.
-M.Sc. Marketing,
Helsinki University.
-Lean Six Sigma Green Belt.
-MBA Studies.
10+ years Customer Operation
Manager of large accounts in
B2B Sales and 12+ years of
team management. Jari brings a
lot of seniority to the team.
-M.Sc. Biochemistry, University
of Oulu.
-1 Peer reviewed pulication, 1
international presentation.
Intellectual property rights
course and first patent filed in
2020.
Experience in teaching dance,
English and elementary school.
www.finnadvance.com
Prateek Singh, CEO
science@finnadvance.comCopy protected with Online-PDF-No-Copy.com

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HealthBIO 2020_Prateek Singh_Finnadvance

  • 1. Prateek Singh, CEO Human biology replicated reliably science@finnadvance.com
  • 2. High cost and inefficient drug development Total cost: $2.6 billion 5k – 10 k compounds 100 – 500 compounds 50 – 250 compounds 3-5 compounds 1 compound HUMAN 5+ years 10+ years 12+ years Prateek Singh, CEO science@finnadvance.com
  • 3. In-development Drugs Fail in Clinical Trials HUMAN Drugs have different effects on 2D cell cultures and animals vs humans →90 % of drugs validated on animals fail during human clinical trials →Cell models and animal models do not adequately represent the human biology →A large part of the total pharma R&D budget is spent on the failing drugs Prateek Singh, CEO science@finnadvance.com Organ-on-Chip models allow significant saving in dollars (HUNDREDS OF MILLIONS) and major timelines (YEARS) Lancet. 2011 Jun 4;377(9781):1915
  • 4. Impact of Finnadvance’s technology In 5 years drug discovery costs are estimated to decrease 10-26% as a result of this technology. “If organ on chip was capable of identifying appropriate biomarkers, it would be the “Holy Grail” of biotechnology” Prateek Singh, CEO science@finnadvance.com
  • 5. Rare disease: blood vessel malformation Patient-derived cells Our biomimetic platform Human disease-on-chip Vascular anomaly organ-on-chip model Prateek Singh, CEO science@finnadvance.com
  • 6. Organ-on-chip Market Forecast 2015 2020 Timescale (year) 2025 100B 10B 1B 100M 10M MarketSize,Log.Scale (USD) Animal Research In Vitro 3D In Vitro Organ on a Chip Prateek Singh, CEO science@finnadvance.com Ref : https://www.alliedmarketresearch.com/organ-on-chip-market Ref : Organs on Chips 2017 report, March 2017, Yole Developpement
  • 7. -M.Sc. Protein Tech and Biochemistry, University of Oulu. -B.Tech Biotechnology, National institute of technology, India. -5 peer reviewed publications. -22 international presentations. Prateek was born in India, and after living in several countries found a home in the scientific community of Oulu, Northern Finland. Prateek’s multi-disciplinary know-how was needed for an EU Project aiming to uncover core mechanisms of initiation and maintenance of Vascular Anomalies. The study would be done on the Organ-on-Chip platforms he would build. He founded Finnadvance to commercialize this innovation and make drug discovery faster and cheaper, while eliminating the use of laboratory animals. Prateek is a huge fan of science. He is extremely proud of having worked on projects funded by NASA, ESA, the Academy of Finland and TEKES. Prateek Singh CEO & Founder Jari Moilanen COOMinna Kihlström CSO Tuan Nguyen CTO Tuomas Nurmi CMO Highly Skilled & Diverse Team Prateek Singh, CEO science@finnadvance.com -Ph.D. Vascular Biology, Uni. of Oulu -M.Sc. Biochemistry and Cell Biology, Oulu University. -M.Sc. Thesis: Institute for Cancer Research, University of Oslo, Norway. -3 High-impact peer reviewed publications. 3 Supervised Thesises. Minna brings 8+ years cell culture and in vitro research, 6+ years in vivo mouse modelling and 7+ years microscopy experience to the team. -B.Eng & M.Sc in Biomedical Engineering International University, Vietnam. -Microtechnology research trainee, University of Sheffield, UK. -Ph.D. Studies in Biochemistry and Molecular medicine, University of Oulu. -2 Peer reviewed publications, 4 international presentations. Tuan is a Biochemical Engineer who raised 2 research funding before finishing his M.Sc. He has also won 2 young entrepreneur competitions. -M.Sc. Marketing, Helsinki University. -Lean Six Sigma Green Belt. -MBA Studies. 10+ years Customer Operation Manager of large accounts in B2B Sales and 12+ years of team management. Jari brings a lot of seniority to the team. -M.Sc. Biochemistry, University of Oulu. -1 Peer reviewed pulication, 1 international presentation. Intellectual property rights course and first patent filed in 2020. Experience in teaching dance, English and elementary school.