Health tech hot list, June 2018, London

Who are we?
• Specialists in legal solutions across the private and
public sectors
• Sector experts, working in partnership with our
clients
• Award winning Health sector specialists
• Leading IP, IT, data, commercial and corporate
lawyers in the Technology space
• HealthTech experience and extended network

Hambro Perks
Peter Soliman – General Counsel,
Hambro Perks
Kate Burns – CEO, Media Tech,
Hambro Perks

7
An Introduction to Hambro Perks
The destination of choice for
technology entrepreneurs
LONG-TERM AND
PERFECTLY ALIGNED
• Patient capital
• Together
BUSINESS BUILDING
• Expertise
• Support
GOING GLOBAL
• Global ambition
• Global network
AGGRESSIVE AND
PATIENT
• Our culture
• Our approach

8
An Introduction to Hambro Perks
Hambro Perks is an early stage investment firm focused on the high growth technology space.
STRUCTURE
Investment
company and
business builder,
we provide
continuous
support
CAPABILITIES
Capabilities across VC, fund
management, and
entrepreneurship – having
invested from incubation to
seed to follow-on
investments
CULTURE
Entrepreneurial culture
given our team is composed
of former entrepreneurs and
angel investors
NETWORK
Strong
relationships
with company
founders, angels,
venture funds
and industry
experts
5*38 205
IN VE S T M ENT S
IN
H E A L T H T E CH
N A T IONAL IT IE S
OF B A CK E D
B U S INESSE S
POR T F OL IO
COM PA N IE S
S E CT OR S W IT H
D E E P
E X PE R T ISE
* 2 i n v e s t m e n t s p e n d i n g

9
Our Approach
Support: through our support services (e.g. accounting, legal, digital) and strategic
advice, we help our portfolio grow
Partnerships: we work closely with a range of other investors, including our
shareholders, to help scale businesses
Our investment thesis is focused on picking high quality entrepreneurs and businesses, and backing them over the
long term.
Wide range of global opportunities sourced from our:
(1) wide network, (2) partners, (3) events
Getting in early or at
inception
Conducting rigorous
due diligence
Follow-on investing Exit at the right time
Active ownership: we provide close involvement in our businesses, including board
membership

10
What we Look for in our Investments
We always look at important traits with all our investments in startups and founders.
Tech-related
Scalable businesses
Competitive advantage
Innovative ideas
We want to back & build innovative and disruptive businesses, therefore will
concentrate on finding unique and exciting ideas.
Our goal is to be a leading, global Tech business - to do this we need to back
businesses that are scalable on a global platform.
As a Tech company the businesses we back need to have an element of
technology surrounding their idea.
Our businesses will all have differentiating advantages in product, service and
economics, with compelling barriers to entry and intellectual property.
Brilliant teams
The people behind any team are the driving force for an idea. We will always
ensure we back strong, reliable and capable teams.
Healthcare Focus:
Within the healthcare sector, we look for opportunities in innovative healthcare services, digital healthcare and
healthcare support services, clinical tools, processes or applications, devices

11
What help we provide
Permanent capital with
follow-on funding
Highly experienced, active
investors
Comprehensive network
Internationalisation &
scaling expertise
Extensive support systems
Early-stage
With our substantial experience, we are experts and industry
specialists when it comes to growing early-stage businesses.
Our extensive network, built through our partners and expert
industry knowledge, allows us to find the best companies
and open valuable doorways for all our founders.
With our expertise and network we want to be fully involved
with all of our businesses by maintaining close relationships
with management and taking Board seats.
Investing off our balance sheet (and not from a fund) means
we can invest permanent capital with a view to follow-on,
allowing us to be patient with our winners.
With a proven track record at internationalisation, we can be
globally focussed and will always look to scale our businesses
overseas when we want to.
Through Hambro Perks, we are able to provide highly
valuable support services such as legal, accounting, tech,
digital media.
There is a skills and funding gap with Angel Investors and VCs that Hambro Perks is able to fill:

12
Example of our Health-tech Investments
INVESTMENT
PENDING
Software for
clinics
management
Using advanced
sensor
technology and
machine learning,
Kraydel offers a
non-intrusive
solution to care.
Elderly people
can live at home
and Kraydel will
intelligently
notify their care
givers if anything
seems amiss.
Echo is the
simple way to
manage repeat
prescriptions
through a
convenient, easy
to use app.
Fully integrated
with NHS GPs,
Echo’s clients can
have their
medications
delivered to
home and the
app enables
reminders.
Vida provides
high quality
carers all across
the UK to assist
the elderly in
their day to day
needs.
Using smart
technology, Vida
ensures that each
client’s care plan
is up to date for
the client and
their family to
view.
INVESTMENT
PENDING
Non-invasive
technology for
the cure of
depression and
other conditions

13
Venture Partners
Healthcare Venture Partner
• Tony is currently a non-executive director at various companies including
Barchester, one of the UK’s largest residential care home businesses, Spire
Healthcare, the leading UK listed private hospital and healthcare provider,
and Totally plc, an AIM quoted leading provider of out-of-hospital care
• He also serves as Chairman of CW+, the official charity of Chelsea and
Westminster Hospital NHS Foundation Trust
• For nearly nine years up to late 2013, he was Chief Executive of the British
Medical Association
• Prior to joining the BMA as Chief Executive, Tony was in investment banking
for over 25 years, most recently as a partner at Hawkpoint
• Previously, he was at BNP Paribas where he was Global Head of the Equities
Division, a member of the Managing Board of the Group and a member of
its four-person worldwide Corporate Finance Committee
• Prior to that he was at Merrill Lynch both in London and New York
• Tony has also held non-executive director positions with various
organisations including Southern Housing Group, one of the country’s
largest providers of social housing, where he served on the main board for
nine years until 2013, and Scope, which focuses on cerebral palsy and is one
of the UK’s largest charities.
Hambro Perks provides its companies with access to its Venture Partners who are successful
operating veterans in their respective fields
Tony Bourne

14
ENTREPRENEUR
S
SHAREHOLDERSOUR COMPANIES
VENTURE
PARTNERS
Family
Offices
Broader
HP
Network
Capital
Market
s
Investment
Partners
Angel
Investors
NEDs/
Advisors
Become part of
our community,
and work closely
in partnership

15
Vida – A Hambro Perks Portfolio
Company

Proximity Care have built a viable
business based on a small initial
investment, launching a product
on the market with regular sales
and no existing debt.

Wandering behaviours occur in up to
63% of elderly people living with
dementia.

Main application:
Wandering alarm

Secondary application:
Various - Partnering
with care systems

Pic of person lost Unlike other products
on the market, the
Proximity Button is a
warning device rather
than a tracking device.

Simpl
e to
use
Operat
es
withou
t
phone
signal
Reliabil
ity
Mobili
ty
Priva
cy
Cost of
owners
hip
Batte
ry life
Likeliho
od of
remova
l by
wearer
Total
(out of
24)
Proximity
Button
3 3 2 3 3 3 3 3 23
GPS
tracker
2 1 2 3 1 1 1 1 12
In-home
alarm
system
3 3 2 1 3 2 3 1 18
GPS
smartpho
3 1 2 3 1 3 2 1 16

The Team
Founder/Director
Natalie Price
Healthcare Ind. Advisor
Chris Shilling
Key Business Advisor
Jon Rees
Financial Advisor
David Walker

In use in 17 care homes in
Denmark
Over 350 units already sold
At market since 2017
Partnership with company in
Silicon Valley

Dementia Carer
Market
Care Home
Market
U
K
670,000 22,000
E
U
7.5 million 60,000
U
S
3.3 million 67,000
We intend to grow in both core markets
for the Button; institutional care
providers and individual carers.

• Additional Markets
• Product development

Investment
• Series A funding
• £500,000
• Applying for SEIS

We are truly passionate about our first
product and believe there is a real gap in
the market for Proximity to become
market leader of well-designed products
that could change lives.

Disruptive and ground breaking Healthcare
delivered wherever it is needed

We are building the worlds most advanced
Medical grade
Wearable
Vitals signs monitor
that uses advanced A.I. and
Supervised machine learning

We are doing this in collaboration
with 5 Academic University Hospitals who
believe so much in what we doing that they are
Investing 1.2m Euros to build our vision
While the money is important, our biggest
advantage is
our unparalleled access to some of the best
Medical expert knowledge in the world.

Hi
I am Dr Shiran Gunasekera
The medical director of Sentinel
We have a world class team of engineers and developers
Who have a passion for innovation and pushing tech boundaries
We are a bunch of geeks who want to change the world
If what we were doing were easy, I would not be here today
Every day we get up and can’t wait to start work. It is a true passion
We all feel privileged to be working on our project because
It will change the world.

When the 5 University Hospitals chose us
They turned down Philips
They turned down G.E. Healthcare
They turned down Siemens
They turned down Oxford University
and then they turned down 100 other companies from across the
EU
We are the only UK company left in the process.
They scored us 810 for innovation and quality of
our team

Meet Sentinel
The worlds most advanced wearable Vital signs monitor
Sentinel “Will advance the field ahead – The companies drive for innovation and pushing boundaries
is clear.”
Great feedback from 5 Academic University Hospitals
• A.I. Pattern recognition – looking for trends indicating conditions like Sepsis
• Sentinel detects conditions BEFORE the are life threatening
• ECG, Heart Rate, SPO2, Respiration rate and blood pressure every 120 secs 24x7
• Supervised Machine learning – Sentinel learns from clinicians – It gets smarter.
• Calculating clinical risk – Sentinel knows when you are getting better or not
• Group based alerting when deterioration is detected
• Works off-grid – No connection is needed – Expert advice is always available
No scary wires – Does not look like it was made for Frankenstein!

We wrote our mission statement 4 years ago because we saw the problem coming
“To give every human being access to an
electronic medical advising device that can
deliver the best advice available to any ailment
they may have or are about to contract
anywhere and at any time.”
At the time, it was science fiction
We’re about to make it ‘Science fact’.

1 in 4 Europeans will be Over 65 by
2025
The world is going to need more
monitoring
Both in hospitals and at home

If you would like to be involved or want to
know more, please get in touch at
www.sentinelsensor.co.uk
We would love to hear from you
Thank-you

THE BIRTH OF ASPIRATIONAL
ORAL HYGEINE
THIS DOCUMENT CONTAINS CONFIDENTIAL, PROPRIETARY INFORMATION. YOUR REVIEW OF THIS
DOCUMENT CONSTITUTES YOUR AGREEMENT TO KEEP ALL SUCH INFORMATION CONFIDENTIAL, TO USE
THE INFORMATION SOLELY IN CONNECTION WITH SIMPLY TEETH ONLINE LTD. (SIMPLY TEETH) SUPPORT
(THE “PROPERTY”), OR PARTNERSHIP OR LICENSING AGREEMENT WITH SIMPLY TEETH AND NOT TO
REPRODUCE, REDISTRIBUTE OR OTHERWISE DISCLOSE ITS CONTENTS TO ANY PERSON OR ENTITY
OUTSIDE YOUR ORGANISATION. YOU FURTHER AGREE TO PROMPTLY RETURN THE ATTACHED UPON
REQUEST FROM SIMPLY TEETH ONLINE LTD.
THE INFORMATION IN THIS DOCUMENT REPRESENTS INDEVS CURRENT ESTIMATES AND ASSESSMENTS IN
CONNECTION WITH THE PROPERTY. ACTUAL EVENTS AND CONDITIONS MAY DIFFER MATERIALLY FROM
SIMPLY TEETH ESTIMATES AND ASSESSMENTS. ADDITIONALLY, THE ASSUMPTIONS UTILISED BY SIMPLY
TEETH IN PREPARING THE INFORMATION MAY DIFFER MATERIALLY FROM ACTUAL EVENTS. THERE CAN
BE NO ASSURANCE THAT THE ESTIMATES AND ASSESSMENTS WILL REPRESENT AN ACCURATE
REFLECTION OF LOCAL OR NATIONAL ECONOMIC CONDITIONS, ACTUAL EVENTS, OR ACTUAL
INVESTMENT PERFORMANCE.
THIS CONFIDENTIAL MEMORANDUM HAS BEEN PREPARED BY SIMPLY TEETH. IT DOES NOT PURPORT TO
BE ALLINCLUSIVE OR TO CONTAIN ALL OF THE INFORMATION THAT A PROSPECTIVE INVESTOR MAY
DESIRE. SIMPLY TEETH DOES NOT MAKE ANY REPRESENTATION OR WARRANTY, EXPRESSED OR IMPLIED,
AS TO THE ACCURACY OR COMPLETENESS OF THIS CONFIDENTIAL MEMORANDUM OR ANY OF ITS
CONTENTS, AND NO LEGAL LIABILITY IS ASSUMED OR TO BE IMPLIED, BY ANY OF THE
AFOREMENTIONED WITH RESPECT THERETO. THIS MEMORANDUM HAS BEEN PREPARED SOLELY FOR
INFORMATIONAL PURPOSES TO ASSIST AN INTERESTED PARTY IN DETERMINING WHETHER TO PROCEED
WITH AN IN-DEPTH INVESTIGATION OF THIS INVESTMENT OPPORTUNITY.
SIMPLY TEETH RESERVES THE RIGHT AT ITS SOLE DISCRETION TO REJECT ANY OR ALL PROPOSALS OR
EXPRESSIONS OF INTEREST FOR INVESTMENT IN THIS OPPORTUNITY AND TO TERMINATE DISCUSSIONS
WITH ANY PARTY AT ANY TIME WITH OR WITHOUT NOTICE. IF YOU DO NOT WISH TO PURSUE THIS
MATTER, KINDLY RETURN THIS CONFIDENTIAL MEMORANDUM AT YOUR EARLIEST POSSIBLE
CONVENIENCE. PHOTOCOPYING OR OTHER DUPLICATION IS NOT AUTHORISED.

Business Model Benchmark:
• The men’s grooming industry has been revolutionised by Harry’s
and Dollar Shave Club.
• Both businesses are less than 5 years old and valued at over $1bn
each!
• Both are exclusively targeting men and to date have primarily
focussed on the US market.
• Primary competitive advantages:
• Price - Displaced overpriced
market leaders
• Quality - Sharper blades replaced more
often
• Convenience - Delivered to your door

Dentii’s Model:
• Dentii offers an ideal balance to the Oral Hygiene sector offering a
disruptive combination of benefits to a market prime for change.
• Primary competitive advantages:
• Aspiration: Beautiful, high value products bringing pride of ownership to oral
hygiene.
• Quality: Peerless engineering, elegant operation and a Lifetime warranty
• Performance: 48kHz operation with microprocessor control
• Diagnostics: Analysis of brushing technique and cleanliness levels per tooth.
• Support: Constant AI monitoring with communication and support from your
own Dentist.
• Hygiene: Single use, sustainable, environmentally friendly brush heads
• Convenience: Subscription model delivers oral hygiene consumables to your
door whenever you need them
• Market: Everyone with teeth.

THE BIRTH OF
ASPIRATIONAL ORAL
HYGIENE

DENTII is Aspirational Oral Hygiene -
DENTII is the first aspirational Oral Hygiene brand.
Combining quality, performance, bespoke professional support and a
unique to market sales model, Dentii offers market leading feature
sets in an ecosystem of excellence proving peerless service provision
to the growing international retail market:
• First Design-Lead Oral Hygiene Brand
• First real-time dental analysis of your oral hygiene
• First dentist-customer communication platforms with
integrated dental appointment scheduling
• First to offer truly Hygienic Toothbrushes
• First Sustainable, Serviceable Toothbrush
• First Subscription-Based Oral Hygiene Brand delivered to your
door
• First to offer Oral Hygiene ‘Prescriptions’

Beautiful products, made
to last –Available in a
range of
finishes from
Aluminium to
precious
metals, DENTII is
designed to be
cherished and
to last.
With replicable
batteries,
custom
gearbox and
sensor arrays
and
biodegradable
heads, DENTII is
your lifelong
partner in Oral
Care.

Market Size and Growth -
$34.8B
n
Global Market
Value
2016 and
Growing
• The global oral care market size was valued at USD $34.8 billion in 2016 and is
projected to witness lucrative growth over the forecast period.
• Growing awareness about dental hygiene and rising prevalence of dental
caries are expected to drive the oral care market.
Value of the Global
Oral Care Market
2013 – 2023
CAGR =
3.18%

Geographic Territories -
• In developed countries nearly 97% of
the population uses at least one
variety of toothpaste, 87% of this
population, brushes twice daily.
• Existing mature markets will require a
disruptive brands such as DENTII to
win market share.
• In new markets, saturation is much
lower but growing strongly with
CAGR of around 14% in India alone.
• DENTII will perform well in these
markets as they are more receptive
to new brands where ‘The Big Three’
Oral Care brands have been
established for less time.
Global Oral Care Market by
Territory

Market Segmentation -
• Global market segmentation is
consistent, the majority of revenues are
generated variably from toothbrush
hardware, toothpastes and
mouthwashes.
• Primary position varies between
hardware and toothpaste depending
on prevailing economy.
• Greater disposable income facilitates
greater expenditure on hardware.
• DENTII is disruptive in breaking this
model allowing everyone to access first
tier hardware and consumables
custom configured for their needs and
disposable income.
Market
Segmentation in
China

Market Competition -
This market is becoming more competitive with multiple
small brands slowing making progress into limited sectors of
the market.
• Boka: A combination of competing business they offer a subscription
service for electric brushes and consumables but has no data integration
or communication provision.
• Brushlink: A Seeders graduate, Brushlink are a manual toothbrush
accessory that provides low level data capture for manual brushing. This
“FitBit for your mouth” didn’t provide enough of a value driver for todays
market to gain significant traction. Now Brushlink are offering a subscription
model to help augment failing sales.
• Brushbox: One of the few manual toothbrush subscription businesses, they
rely on providing brushes and consumables but instead of brushes they
offer “sustainable” toothbrushes made from organic materials (but with
Nylon bristles) for improved environmental market perception.
• Morgan’s: Another manual brush offering however Morgan’s are primarily
a subsection bathroom products business in that they provide all bathroom
consumables including shower gels, deodorant, shaving accessories etc

Revenue Model - An Ecosystem of
Profitability
• Primary revenue from subscription based scalable
hardware offerings and prescription toothpastes and
mouthwashes.
• Scalable service provision and monthly payments with
up-front payment for high value items.
• Retail engagement with high-street through products
bundled with annual subscription bundles.
• Dental Practise engagement through discount/royalty
codes providing purchase price with discounts to the
customer and a royalties to the practise.

Revenue Model - An Ecosystem of
Profitability
• Sales through partner dental aggregators once
protocols are established
• Ongoing royalty to practises for all purchases of
prescription products.
• Retail products lock to active customer accounts
preventing device functionality in event of
subscription withdrawal and the secondary
market sale of DENTII products.
• Risk assessment data services provided to dental
insurance providers to provide greater insight to
oral hygiene and to reduce insurance costs.

Self-Funded Entrepreneurism:
• Concept Design Completed
• Brand Design Completed
• Demonstration Prototyping
Completed
• Web-Site Launched
• International Patents and
Trademarks Filed
• Oxford University R&D
Partnership + Licence of
Thermal Product IP
• Application for joint Innovate
UK R&D Grant application
• Kickstarter Campaign
Completed
• £40,000 raised in 5 days
• 71 x Bulk Orders averaging 5 x
brushes per purchase
• Over 2,000 “Likes” on
Facebook
• Corporate interest from
leading UK Dental Practice
Groups
• Retail partners identified
proving 300,000 potential
customers in the UK at
launch.
Traction so Far-

Production Traction -
Premier Supply Chain:
• Top Tier Development/Supply Chain
Management Engaged:
• One Point-Zero Solutions – Hong Kong
• Blue-Chip client base across multiple
markets with global footprint.
• Total Integrity solution with complete IP
robustness and integrity.
• Distribution direct to customer from
Shenzhen Free Trade Zone distribution
centre.
• Commercial engagement assistance in
Asian markets.
• Commercial Launch Q1/Q2 2019
‘…Amazing
Opportunity…’
John Garvey
CTO Cosmo Supply Labs
Ex CTO PCH Intl.
‘…Low-Risk
Strategy…’
Donald MacCallum
Founder One Pont-Zero Solutions
Ex SVP Sales PCH Intl.

The Team -
Dr Sunny Sihra Bds
CEO
Royal London Hospital
School of Medicine and
Dentistry
Simply Teeth Online Ltd.
David Fowler Ma(RCA),
Ba(Hons)
CTO/COO
Royal College of Art
Central Saint Martins School of
Art and Design
Innovation Development
Solutions Ltd.
Professor Justin
Stebbing MD MA
FRCP FRCPath PhD
Chairman Advisory
Board
Professor of Cancer
Medicine and
Oncology, Consultant
Oncologist, Imperial
College and Imperial
College Healthcare
NHS Trust
Mark Aichroth
Member Advisory Board
Director at Dental Health
Holdings
.

Investment is required
to:
• Finance Op-Ex and
Cap-Ex
• Drive Launch
Marketing and PR
• Fund UK Product
Launch
• Finance Channel-
Load Production
Volumes
Investment Requirement -
£2m - 20% Share in DENTII Ltd
Projected UK Sales Volumes – Year 3
Total Number of Electric Manual
Customers
19,123,65
0
Total Number of Electric Toothbrush
Customers 8,195,850
Total Annual Projected Manual
Toothbrush Sales
76,494,60
0
Total Annual Projected Electric
Toothbrush Sales 4,097,925
Projected Dentii Electric Brush Market
Share 4%
Projected Dentii Manual Brush Market
Share 1%
Projected Dentii Manual Toothbrush
Sales (£)
£11,474,1
90
Projected Dentii Electric Toothbrush
Sales (£)
£13,111,7
21
Projected Dentii Electric Subscription
Sales (£)
£19,670,0
40

THE BIRTH OF ASPIRATIONAL
ORAL HYGEINE
Thank
You

All information correct at time of production.
The information and opinions expressed within this document are
no substitute for full legal advice. It is for guidance only and
illustrates the law as at the published date. If in doubt, please
telephone us on 0370 270 6000.
© Browne Jacobson LLP 2018 – The information contained within
this document is and shall remain the property of Browne
Jacobson. This document may not be reproduced without the prior
consent of Browne Jacobson.

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