This document provides information on prevention and control of substance use and abuse. It discusses three types of prevention programs: universal, selected, and indicated. Universal programs address risk factors for all children in a given setting like school or community. Selected and indicated programs are intended to address the needs of specific children and teenagers. The document then provides tips for teenagers to avoid substance abuse which include learning to say no, choosing friends wisely, communicating with parents, enjoying life without drugs, remembering rules on alcohol and drugs, getting educated on effects of substances, being a role model, planning ahead, talking about issues, and seeking help if needed.