This document provides an overview of Harvard Bioscience, Inc. including its history, global footprint, recent strategic moves, product segments and brands, commercial channels, the life science market, financial performance, guidance, and stock information. Key points include Harvard Bioscience's global operations, realignment to increase efficiencies and reinvest savings, focus on growth through commercial excellence, product development and acquisitions, and financial targets of maintaining 2014 revenue with improved earnings.
Early asset development and commercialization: Partnering for successCello Health
The document discusses early asset development and commercialization, and partnering arrangements. It introduces Cello Health and their services in market research, strategic consulting and scientific communications. It then discusses evaluating potential partners based on their capabilities and how they match a company's needs, as well as considering different types of partnering arrangements like licensing, acquisitions, joint ventures and more. Managing the value of early assets across development is also emphasized.
Valeant Pharmaceuticals announced its acquisition of Bausch + Lomb to create a global leader in eye health. The $8.7 billion deal will make Valeant a top competitor in ophthalmic pharmaceuticals, surgical products, and vision care. Valeant expects to achieve at least $800 million in cost synergies by the end of 2014. The combined company will have a strong presence across major eye health segments and geographies, with leadership in attractive emerging markets.
This document summarizes the 2015 annual meeting of Valeant Pharmaceuticals International, Inc. held on May 19, 2015 in Laval, Quebec, Canada. It introduces the board of directors and executive management in attendance. It reports that all proposed resolutions, including electing directors and ratifying the auditor, received over 90% shareholder approval. The document provides an overview of Valeant's business model, product portfolio, acquisition and R&D strategies, and highlights key pipeline and launch products. It concludes by emphasizing Valeant's track record of strong financial performance and shareholder returns.
Valeant provided an update on its Q4 2014 operational highlights and guidance. It reported strong organic growth across most business units, with total company organic growth expected to be over 12% for Q4 and over 10% for the full year. It also made progress on its R&D pipeline and completed several business development deals. Valeant maintained its revenue guidance of $2.1-2.3 billion for Q4 but raised its cash EPS guidance to over $2.55 and reiterated its adjusted cash flow from operations guidance of approximately $600 million.
The document provides an overview of Pfizer Inc., including its business segments, geographic reach, goals, mission/values, history, strategy, external environment analysis, internal environment analysis, and recommendations. It analyzes Pfizer's pharmaceutical, animal health, and corporate/other business segments. Key points include Pfizer operating in over 150 countries, goals of growing in emerging markets and optimizing its patent-protected portfolio, and an analysis of its competitive environment and internal financial performance compared to rivals. One recommendation is for Pfizer to focus on emerging markets like Asia, China, and India.
This document provides a strategic analysis of Pfizer, a major bio-pharmaceutical company. It begins with a brief history of Pfizer, founded in 1849, and its evolution from producing food ingredients and medicines during the Civil War to developing antibiotics like penicillin and pharmaceutical drugs. The document discusses Pfizer's current leadership and top competitors like Novartis, Merck, and AstraZeneca. It analyzes Pfizer's mission and vision statements according to best practices. Finally, it presents an external factor evaluation matrix to examine opportunities and threats in Pfizer's external environment, identifying technology advancement as a key external factor for the company.
Valeant Pharmaceuticals International, Inc. held a presentation at the Jefferies Autumn 2015 Global Healthcare Conference on November 18, 2015. The presentation provided an overview of Valeant, including that it is a multinational specialty pharmaceutical company focused on faster-growing therapeutic areas and geographies. It also summarized Valeant's business model, culture of ownership, commitment to innovation, and highlighted recent product launches and updates.
Valeant provides revised guidance for Q4 2015 and full year 2015 due to impacts from separating from Philidor and transitioning to a new partnership with Walgreens, estimating a $250M revenue impact from Philidor separation and $150M from the Walgreens transition. Valeant also provides initial guidance for 2016, estimating $12.5-12.7B in revenue and $13.25-13.75 per share in adjusted EPS, representing over 20% growth compared to updated 2015 guidance.
Early asset development and commercialization: Partnering for successCello Health
The document discusses early asset development and commercialization, and partnering arrangements. It introduces Cello Health and their services in market research, strategic consulting and scientific communications. It then discusses evaluating potential partners based on their capabilities and how they match a company's needs, as well as considering different types of partnering arrangements like licensing, acquisitions, joint ventures and more. Managing the value of early assets across development is also emphasized.
Valeant Pharmaceuticals announced its acquisition of Bausch + Lomb to create a global leader in eye health. The $8.7 billion deal will make Valeant a top competitor in ophthalmic pharmaceuticals, surgical products, and vision care. Valeant expects to achieve at least $800 million in cost synergies by the end of 2014. The combined company will have a strong presence across major eye health segments and geographies, with leadership in attractive emerging markets.
This document summarizes the 2015 annual meeting of Valeant Pharmaceuticals International, Inc. held on May 19, 2015 in Laval, Quebec, Canada. It introduces the board of directors and executive management in attendance. It reports that all proposed resolutions, including electing directors and ratifying the auditor, received over 90% shareholder approval. The document provides an overview of Valeant's business model, product portfolio, acquisition and R&D strategies, and highlights key pipeline and launch products. It concludes by emphasizing Valeant's track record of strong financial performance and shareholder returns.
Valeant provided an update on its Q4 2014 operational highlights and guidance. It reported strong organic growth across most business units, with total company organic growth expected to be over 12% for Q4 and over 10% for the full year. It also made progress on its R&D pipeline and completed several business development deals. Valeant maintained its revenue guidance of $2.1-2.3 billion for Q4 but raised its cash EPS guidance to over $2.55 and reiterated its adjusted cash flow from operations guidance of approximately $600 million.
The document provides an overview of Pfizer Inc., including its business segments, geographic reach, goals, mission/values, history, strategy, external environment analysis, internal environment analysis, and recommendations. It analyzes Pfizer's pharmaceutical, animal health, and corporate/other business segments. Key points include Pfizer operating in over 150 countries, goals of growing in emerging markets and optimizing its patent-protected portfolio, and an analysis of its competitive environment and internal financial performance compared to rivals. One recommendation is for Pfizer to focus on emerging markets like Asia, China, and India.
This document provides a strategic analysis of Pfizer, a major bio-pharmaceutical company. It begins with a brief history of Pfizer, founded in 1849, and its evolution from producing food ingredients and medicines during the Civil War to developing antibiotics like penicillin and pharmaceutical drugs. The document discusses Pfizer's current leadership and top competitors like Novartis, Merck, and AstraZeneca. It analyzes Pfizer's mission and vision statements according to best practices. Finally, it presents an external factor evaluation matrix to examine opportunities and threats in Pfizer's external environment, identifying technology advancement as a key external factor for the company.
Valeant Pharmaceuticals International, Inc. held a presentation at the Jefferies Autumn 2015 Global Healthcare Conference on November 18, 2015. The presentation provided an overview of Valeant, including that it is a multinational specialty pharmaceutical company focused on faster-growing therapeutic areas and geographies. It also summarized Valeant's business model, culture of ownership, commitment to innovation, and highlighted recent product launches and updates.
Valeant provides revised guidance for Q4 2015 and full year 2015 due to impacts from separating from Philidor and transitioning to a new partnership with Walgreens, estimating a $250M revenue impact from Philidor separation and $150M from the Walgreens transition. Valeant also provides initial guidance for 2016, estimating $12.5-12.7B in revenue and $13.25-13.75 per share in adjusted EPS, representing over 20% growth compared to updated 2015 guidance.
Performing Competitive Intelligence in a Pharmaceutical CompanyAnthony Russell
The document provides an overview of competitive intelligence in the pharmaceutical industry. It defines competitive intelligence as the collection and analysis of information to anticipate competitors' actions. Competitive intelligence is critical in pharmaceuticals due to long development timelines, high costs, and various sources of competition. The document outlines the differences between competitive information and intelligence, the process of conducting competitive intelligence including developing key intelligence questions, and available sources of information in the industry.
Valeant reported strong financial results for Q2 2015 that exceeded guidance. Key highlights included continued outperformance of U.S. businesses such as dermatology and ophthalmology, and a fast start for recently acquired Salix which exceeded expectations. Valeant increased full-year 2015 guidance due to the outperformance and approval of a new drug indication. Several acquisitions were also completed or announced in the quarter to further expand the company's business.
Valeant held an investor conference call to discuss its relationship with Philidor RX Services, LLC, a specialty pharmacy. Valeant had a pilot program with Philidor starting in 2012 and obtained an option to acquire Philidor in January 2013. Philidor's network grew substantially since then and represented 6.8% of Valeant's revenue in Q3 2015. However, questions remained around Valeant's diligence, oversight, and control of Philidor as well as Philidor's accounting and disclosure.
This document discusses biotechnology R&D strategies and corporate strategy. It begins with an overview of the biopharmaceutical industry and challenges with early stage funding. The concept of strategy and purposes of a good strategy are then explained. Key elements of R&D performance strategies including architecture, processes, people and portfolio are covered. Case studies of innovation and biosimilar R&D strategies from companies like GSK, Wyeth and Novartis are summarized. The document concludes that different companies pursued different strategies based on their core hypotheses to address R&D productivity issues. Benchmarking capabilities is important for companies looking to enter the biosimilars market during the biologics patent cliff.
This document discusses ChromaDex's business model and forward-looking statements. It summarizes ChromaDex's goals to lead research in the natural products industry through its standards and analytical services business, gain market intelligence to identify new ingredient technologies, and commercialize novel proprietary ingredients. One such ingredient is pTeroPure, a clinically-studied pterostilbene ingredient from blueberries that ChromaDex has developed and monetized through various partnerships and clinical studies showing its benefits for lowering blood pressure.
New Product Planning Strategies to Ensure Organizational Robustness for LaunchAnthony Russell
- New product planning strategies are important for small to medium sized biopharma companies to ensure organizational robustness for product launches.
- Early commercial planning can impact a product's launch success by clearly defining its value proposition and positioning relative to competitors.
- A framework for evaluating new targets and indications involves assessing factors like clinical development feasibility, regulatory pathways, market potential, and risks. Strategic segmentation of patient populations also guides efficient planning.
- Lifecycle management strategies like pursuing new indications can extend revenue and provide competitive barriers to improve return on investment.
Galenica Group pursues a strategy of long-term growth through diversification across complementary healthcare sectors including pharma, logistics, retail, and healthcare information. This creates synergies and distributes risk effectively. The analysis shows Galenica outperforms pure players in these sectors by 37% due to synergies from operating across the value chain and leveraging strategic resources like bargaining power, reputation, and healthcare market knowledge. Recommendations include continuing international expansion in pharma and logistics to control more of the value chain abroad, strengthening national positions, and developing through strategic alliances initially before potential acquisitions to gain control while managing risks and costs. Corporate governance is currently effective but succession planning is needed as the CEO
Building a Business Case for New Product Planning in a Small Company EnvironmentAnthony Russell
Presented at the 2nd New Product Planning Summit by ExL Events in Boston (Dec 8, 2017). An overview of why commercial strategy is needed early in product development. As pressures continue to mount in drug development (crowded markets, payer and access issues, etc.), it is becoming critical to focus on the early stages of drug development. Working early with research and development teams to evaluate the commercial viability of programs will benefit companies of all sizes to maximize their portfolio of therapeutic candidates.
Lifecycle Management in the Pharmaceutical IndustryAnthony Russell
This document discusses lifecycle management strategies in the pharmaceutical industry. It begins by outlining the key drivers for effective lifecycle management, including the high costs of drug development and need to extend patent protection. Several lifecycle management strategies are then described, such as developing new indications, formulations, delivery methods, or integrating digital health tools. The document emphasizes that lifecycle management planning should begin early and consider factors such as clinical feasibility, regulatory pathways, intellectual property and commercial impacts when selecting strategies.
How to Work Effectively with Research Teams in New Product PlanningAnthony Russell
Presented at the 3rd New Product Planning Summit. The presentation was designed to help professionals in New Product Planning to present a case for why commercial strategy input is needed early in the process of developing new therapeutics. The presentation also includes suggested approaches and tools to help with effective engagement with Research teams.
Valeant reported financial results for Q4 2014 and full year 2014. Q4 revenue was $2.3 billion, a 10% increase over Q4 2013. Cash EPS was $2.58 compared to $2.15 last year. Guidance for Q1 2015 includes revenue of approximately $2.2 billion and cash EPS of $2.55. Valeant also provided an update on the Dendreon and Salix acquisitions.
The document summarizes Valeant Pharmaceuticals International's investor day agenda on June 21, 2012. The agenda included opening remarks by Mike Pearson, financial discussions by Howard Schiller, business overviews by Rajiv De Silva, and presentations on emerging markets and specialty pharmaceuticals. Guests in attendance included board members and senior leadership. The document also provided important information about forward-looking statements and non-GAAP financial measures.
This is part of the MaRS BioEntrepreneurship series.
Speaker: Lynne Zydowsky, Ph.D., Managing Principal Zydowsky Consultants
* Explore the development of regulated drugs and devices
* Understand where and how value is generated in the pharmaceuticals industry
* Appreciate the interplay between science and business in a biotech company
To download a copy of the audio for this presentation, please go to:
http://www.marsdd.com/bioent/oct16
For the event blog and Q+A, please see:
http://blog.marsdd.com/2006/10/17/bringing-together-art-and-science/
Morgan stanley global healthcare conference 2014Quintiles2014
- Quintiles is a leading biopharmaceutical services company that provides drug development and integrated healthcare services.
- They have a track record of profitable growth with adjusted service revenues growing at an 8.3% CAGR from 2010-2013.
- Their vision is to "bring people and knowledge together for a healthier world" and their strategy focuses on differentiated offerings, new markets, and world-class customer relationships.
- Olivier Brandicourt, CEO of Sanofi, presented at the JP Morgan Healthcare Conference in San Francisco on January 9, 2018.
- The presentation outlined Sanofi's progress on its 2020 strategic roadmap and focused on building leadership in specialty care and strengthening its diabetes portfolio.
- Sanofi is sustaining innovation in R&D to support long-term growth through advancing its pipeline of over 70 projects, with 9 potential regulatory submissions expected in the next 18 months.
This document summarizes Sanofi's Sustaining Innovation Analyst Day held on December 13, 2017 in Paris. It outlines Sanofi's strategic focus on sustaining innovation in R&D through developing high-value projects, improving launch pipeline and portfolio prioritization processes. Sanofi's R&D model focuses on key disease areas like immunology, oncology, rare diseases, diabetes and vaccines. The presentation highlights 9 potential product submissions in the next 18 months and over 10 new pivotal trials expected to start in the next 12 months. Sanofi aims to financially discipline its R&D investments based on rigorous project prioritization methodology.
The document discusses ChromaDex's business model, which involves a legacy standards and analytical services business that provides market intelligence used to identify and acquire early-stage ingredient technologies. These technologies are developed and commercialized in multi-billion dollar markets like dietary supplements, food and beverage, cosmeceuticals, and pharmaceuticals. An example case study is provided on ChromaDex's acquisition, development, and commercialization of pterostilbene under the brand name pTeroPure, including a clinical study showing it significantly lowers blood pressure.
The importance of getting a Biotechnology launch right the first time and the difficulty of recovering from a slow sales trajectory suggest that there is a need to evolve the go-to-market approach to ensure launch success. Successfully bringing a product to market has been increasingly difficult as the U.S. Healthcare Market has evolved since implementation of the Affordable Care Act. Pricing has become more controlled - and value based - as healthcare costs have increased to an unsustainable level. Customers realize there is little product differentiation and the traditional Field Sales representative based go-to-market models are struggling to effectively communicate the value proposition to more demanding and informed customers and stakeholders. The results of our pre-launch survey are provided here along with recommendations for what Biotechnology companies can do to improve launch readiness.
This presentation explores some of the underlying issues responsible for declining pharma R&D productivity, and provides a new, fully integrated approach to reverse this trend by navigating R&D projects and portfolios through the risk-return landscape in real time.
A case study demonstrates how this system can be used in practice to improve the risk-return profile of a Phase 2 development project according to risk appetite.
This presentation focuses on R&D in the pharmaceutical industry, however the approach can be used to manage and optimize the risk-return profile of any business asset at any stage of its lifecycle, at any level, in any industry.
Making Key Decisions in New Product Planning When “Perfect” Information is No...Anthony Russell
Presentation given at New Product Planning Summit 2021.
Learning Objectives:
* Review the types of decisions typically made in New Product Planning
* Discuss the nature of information available to support decision-making in New Product Planning
* Review the impact and context of decision-making in New Product Planning
* Review potential approaches to assist in New Product Planning decision-making
Catalent is the global leader in drug development and manufacturing. It has over 1,300 patents and is well-positioned to benefit from substantial industry growth of 6-10% annually through 2020. While pricing pressures could slow industry growth, Catalent's business model focusing on development, delivery, and supply solutions provides long-term stable revenues. The recommendation is to buy Catalent stock, which trades at $29.13 but has a target price of $35.99 based on discounted cash flow analysis.
This document is a quarterly newsletter providing updates on the Philadelphia life science industry. It includes articles on key topics:
1. The first article discusses how to stay informed on key players and emerging companies in a disease area through regularly asking questions about clinical trials, publications, collaborations, regulatory approvals and company pipelines.
2. The second article describes how some health tech companies have found success innovating around changes in healthcare by targeting preventative care, shifting care to the home, using lean processes and collaborating in innovation hubs.
3. Other sections provide information on investment strategies, performance metrics for local biotech companies, acquisitions and a list of companies in an investment index.
Performing Competitive Intelligence in a Pharmaceutical CompanyAnthony Russell
The document provides an overview of competitive intelligence in the pharmaceutical industry. It defines competitive intelligence as the collection and analysis of information to anticipate competitors' actions. Competitive intelligence is critical in pharmaceuticals due to long development timelines, high costs, and various sources of competition. The document outlines the differences between competitive information and intelligence, the process of conducting competitive intelligence including developing key intelligence questions, and available sources of information in the industry.
Valeant reported strong financial results for Q2 2015 that exceeded guidance. Key highlights included continued outperformance of U.S. businesses such as dermatology and ophthalmology, and a fast start for recently acquired Salix which exceeded expectations. Valeant increased full-year 2015 guidance due to the outperformance and approval of a new drug indication. Several acquisitions were also completed or announced in the quarter to further expand the company's business.
Valeant held an investor conference call to discuss its relationship with Philidor RX Services, LLC, a specialty pharmacy. Valeant had a pilot program with Philidor starting in 2012 and obtained an option to acquire Philidor in January 2013. Philidor's network grew substantially since then and represented 6.8% of Valeant's revenue in Q3 2015. However, questions remained around Valeant's diligence, oversight, and control of Philidor as well as Philidor's accounting and disclosure.
This document discusses biotechnology R&D strategies and corporate strategy. It begins with an overview of the biopharmaceutical industry and challenges with early stage funding. The concept of strategy and purposes of a good strategy are then explained. Key elements of R&D performance strategies including architecture, processes, people and portfolio are covered. Case studies of innovation and biosimilar R&D strategies from companies like GSK, Wyeth and Novartis are summarized. The document concludes that different companies pursued different strategies based on their core hypotheses to address R&D productivity issues. Benchmarking capabilities is important for companies looking to enter the biosimilars market during the biologics patent cliff.
This document discusses ChromaDex's business model and forward-looking statements. It summarizes ChromaDex's goals to lead research in the natural products industry through its standards and analytical services business, gain market intelligence to identify new ingredient technologies, and commercialize novel proprietary ingredients. One such ingredient is pTeroPure, a clinically-studied pterostilbene ingredient from blueberries that ChromaDex has developed and monetized through various partnerships and clinical studies showing its benefits for lowering blood pressure.
New Product Planning Strategies to Ensure Organizational Robustness for LaunchAnthony Russell
- New product planning strategies are important for small to medium sized biopharma companies to ensure organizational robustness for product launches.
- Early commercial planning can impact a product's launch success by clearly defining its value proposition and positioning relative to competitors.
- A framework for evaluating new targets and indications involves assessing factors like clinical development feasibility, regulatory pathways, market potential, and risks. Strategic segmentation of patient populations also guides efficient planning.
- Lifecycle management strategies like pursuing new indications can extend revenue and provide competitive barriers to improve return on investment.
Galenica Group pursues a strategy of long-term growth through diversification across complementary healthcare sectors including pharma, logistics, retail, and healthcare information. This creates synergies and distributes risk effectively. The analysis shows Galenica outperforms pure players in these sectors by 37% due to synergies from operating across the value chain and leveraging strategic resources like bargaining power, reputation, and healthcare market knowledge. Recommendations include continuing international expansion in pharma and logistics to control more of the value chain abroad, strengthening national positions, and developing through strategic alliances initially before potential acquisitions to gain control while managing risks and costs. Corporate governance is currently effective but succession planning is needed as the CEO
Building a Business Case for New Product Planning in a Small Company EnvironmentAnthony Russell
Presented at the 2nd New Product Planning Summit by ExL Events in Boston (Dec 8, 2017). An overview of why commercial strategy is needed early in product development. As pressures continue to mount in drug development (crowded markets, payer and access issues, etc.), it is becoming critical to focus on the early stages of drug development. Working early with research and development teams to evaluate the commercial viability of programs will benefit companies of all sizes to maximize their portfolio of therapeutic candidates.
Lifecycle Management in the Pharmaceutical IndustryAnthony Russell
This document discusses lifecycle management strategies in the pharmaceutical industry. It begins by outlining the key drivers for effective lifecycle management, including the high costs of drug development and need to extend patent protection. Several lifecycle management strategies are then described, such as developing new indications, formulations, delivery methods, or integrating digital health tools. The document emphasizes that lifecycle management planning should begin early and consider factors such as clinical feasibility, regulatory pathways, intellectual property and commercial impacts when selecting strategies.
How to Work Effectively with Research Teams in New Product PlanningAnthony Russell
Presented at the 3rd New Product Planning Summit. The presentation was designed to help professionals in New Product Planning to present a case for why commercial strategy input is needed early in the process of developing new therapeutics. The presentation also includes suggested approaches and tools to help with effective engagement with Research teams.
Valeant reported financial results for Q4 2014 and full year 2014. Q4 revenue was $2.3 billion, a 10% increase over Q4 2013. Cash EPS was $2.58 compared to $2.15 last year. Guidance for Q1 2015 includes revenue of approximately $2.2 billion and cash EPS of $2.55. Valeant also provided an update on the Dendreon and Salix acquisitions.
The document summarizes Valeant Pharmaceuticals International's investor day agenda on June 21, 2012. The agenda included opening remarks by Mike Pearson, financial discussions by Howard Schiller, business overviews by Rajiv De Silva, and presentations on emerging markets and specialty pharmaceuticals. Guests in attendance included board members and senior leadership. The document also provided important information about forward-looking statements and non-GAAP financial measures.
This is part of the MaRS BioEntrepreneurship series.
Speaker: Lynne Zydowsky, Ph.D., Managing Principal Zydowsky Consultants
* Explore the development of regulated drugs and devices
* Understand where and how value is generated in the pharmaceuticals industry
* Appreciate the interplay between science and business in a biotech company
To download a copy of the audio for this presentation, please go to:
http://www.marsdd.com/bioent/oct16
For the event blog and Q+A, please see:
http://blog.marsdd.com/2006/10/17/bringing-together-art-and-science/
Morgan stanley global healthcare conference 2014Quintiles2014
- Quintiles is a leading biopharmaceutical services company that provides drug development and integrated healthcare services.
- They have a track record of profitable growth with adjusted service revenues growing at an 8.3% CAGR from 2010-2013.
- Their vision is to "bring people and knowledge together for a healthier world" and their strategy focuses on differentiated offerings, new markets, and world-class customer relationships.
- Olivier Brandicourt, CEO of Sanofi, presented at the JP Morgan Healthcare Conference in San Francisco on January 9, 2018.
- The presentation outlined Sanofi's progress on its 2020 strategic roadmap and focused on building leadership in specialty care and strengthening its diabetes portfolio.
- Sanofi is sustaining innovation in R&D to support long-term growth through advancing its pipeline of over 70 projects, with 9 potential regulatory submissions expected in the next 18 months.
This document summarizes Sanofi's Sustaining Innovation Analyst Day held on December 13, 2017 in Paris. It outlines Sanofi's strategic focus on sustaining innovation in R&D through developing high-value projects, improving launch pipeline and portfolio prioritization processes. Sanofi's R&D model focuses on key disease areas like immunology, oncology, rare diseases, diabetes and vaccines. The presentation highlights 9 potential product submissions in the next 18 months and over 10 new pivotal trials expected to start in the next 12 months. Sanofi aims to financially discipline its R&D investments based on rigorous project prioritization methodology.
The document discusses ChromaDex's business model, which involves a legacy standards and analytical services business that provides market intelligence used to identify and acquire early-stage ingredient technologies. These technologies are developed and commercialized in multi-billion dollar markets like dietary supplements, food and beverage, cosmeceuticals, and pharmaceuticals. An example case study is provided on ChromaDex's acquisition, development, and commercialization of pterostilbene under the brand name pTeroPure, including a clinical study showing it significantly lowers blood pressure.
The importance of getting a Biotechnology launch right the first time and the difficulty of recovering from a slow sales trajectory suggest that there is a need to evolve the go-to-market approach to ensure launch success. Successfully bringing a product to market has been increasingly difficult as the U.S. Healthcare Market has evolved since implementation of the Affordable Care Act. Pricing has become more controlled - and value based - as healthcare costs have increased to an unsustainable level. Customers realize there is little product differentiation and the traditional Field Sales representative based go-to-market models are struggling to effectively communicate the value proposition to more demanding and informed customers and stakeholders. The results of our pre-launch survey are provided here along with recommendations for what Biotechnology companies can do to improve launch readiness.
This presentation explores some of the underlying issues responsible for declining pharma R&D productivity, and provides a new, fully integrated approach to reverse this trend by navigating R&D projects and portfolios through the risk-return landscape in real time.
A case study demonstrates how this system can be used in practice to improve the risk-return profile of a Phase 2 development project according to risk appetite.
This presentation focuses on R&D in the pharmaceutical industry, however the approach can be used to manage and optimize the risk-return profile of any business asset at any stage of its lifecycle, at any level, in any industry.
Making Key Decisions in New Product Planning When “Perfect” Information is No...Anthony Russell
Presentation given at New Product Planning Summit 2021.
Learning Objectives:
* Review the types of decisions typically made in New Product Planning
* Discuss the nature of information available to support decision-making in New Product Planning
* Review the impact and context of decision-making in New Product Planning
* Review potential approaches to assist in New Product Planning decision-making
Catalent is the global leader in drug development and manufacturing. It has over 1,300 patents and is well-positioned to benefit from substantial industry growth of 6-10% annually through 2020. While pricing pressures could slow industry growth, Catalent's business model focusing on development, delivery, and supply solutions provides long-term stable revenues. The recommendation is to buy Catalent stock, which trades at $29.13 but has a target price of $35.99 based on discounted cash flow analysis.
This document is a quarterly newsletter providing updates on the Philadelphia life science industry. It includes articles on key topics:
1. The first article discusses how to stay informed on key players and emerging companies in a disease area through regularly asking questions about clinical trials, publications, collaborations, regulatory approvals and company pipelines.
2. The second article describes how some health tech companies have found success innovating around changes in healthcare by targeting preventative care, shifting care to the home, using lean processes and collaborating in innovation hubs.
3. Other sections provide information on investment strategies, performance metrics for local biotech companies, acquisitions and a list of companies in an investment index.
Hi tech pharmacal co., inc. (hitk) - financial and strategic swot analysis re...raja1233
Hi-Tech Pharmacal Co., Inc. is a pharmaceutical company that develops, manufactures, and markets generic prescription drugs, over-the-counter products, and nutritional supplements. It provides a broad range of products for various diseases and conditions. The company supplies its products to major retail pharmacies, distributors, and government agencies. A SWOT analysis of Hi-Tech Pharmacal found that it has strengths in its diversified product portfolio and large customer base, but weaknesses in competition from larger generic drug companies. Opportunities for growth include expanding its over-the-counter product lines, while threats include increased regulatory scrutiny and pricing pressures.
Agility health investor presentation - investor tab 07.18.16AgilityHealth
Agility Health is a leading healthcare provider focused on physical rehabilitation services. It operates over 155 locations across the US. The presentation provides an overview of Agility Health's business model, growth strategy, and financial performance. It aims to capitalize on the large and fragmented physical rehabilitation industry through acquisitions, organic growth, and its proprietary software system. Key highlights include double-digit revenue and EBITDA growth in recent quarters and an experienced management team.
Regulatory affairs professionals ensure public health by controlling the safety and efficacy of products. They keep track of changing legislation and advise their company on legal and scientific requirements. They collect and evaluate scientific data, present registration documents to regulatory agencies, and obtain marketing authorization for products. A good regulatory affairs professional helps maximize resources and serves as the first point of contact between a company and government authorities.
Strategic management - An Outlook on Growth strategyNeha Kalal
Strategic management involves formulating, implementing, and evaluating cross-functional decisions to achieve organizational objectives. The key stages are strategy formulation, implementation, and evaluation. Strategy formulation involves determining the vision, mission, external/internal analysis to identify strengths, weaknesses, opportunities, and threats. Implementation establishes objectives, policies, motivation, and resource allocation. Evaluation assesses performance and makes corrections. Strategic planning provides financial and non-financial benefits but some firms do not plan due to lack of knowledge, poor structures, or overconfidence. Sun Pharma grew through strategic acquisitions of companies and plants from 1996-2015 to expand globally and into new therapy areas.
Digna Biotech is a biotech company focused on developing clinical therapeutic candidates through partnerships. Its pipeline includes CT-1 for kidney transplant and liver surgery, disitertide for scleroderma, and products for gene therapy, hepatitis C, liver diseases, oncology, and more. The company partners with research centers and universities and is headquartered in Spain. This report provides details on Digna's pipeline products, clinical trials, and company information to help evaluate investment and partnership opportunities.
Cook medical incorporated product pipeline analysisraja1233
Companyprofilesandconferences.com glad to promote a new report on "Cook Medical Incorporated - Product Pipeline Analysis" which is a source for data, analysis, and actionable intelligence on the company’s portfolio of pipeline products also provides key information about the company, its major products and brands.
Impax Laboratories presented at the Cowen & Co Health Care Conference on March 6, 2013. They discussed their progress in improving quality operations and resolving FDA observations. They are committed to improving operations but have more work to do to fully address issues. Impax also outlined their strategy to create long-term growth through diversifying their generic product mix, building their branded neurology pipeline, and pursuing business development opportunities, supported by their strong financial position with $299 million in cash.
Cowen Co Health Care Conference March 6 2013impax-labs
Impax Laboratories is committed to improving its quality operations and resolving an FDA warning letter. It has made significant improvements over the past two years through changes to quality management and increased quality staffing. However, more work remains to be done to complete its quality improvement program and address recent FDA observations. Impax is also focused on growing its generic and branded drug pipelines to target sustainable markets. It has established competencies in complex drug development and delivery and seeks to diversify its generic portfolio and build its neurology-focused branded pipeline.
Tracxn Startup Research — Life Sciences Landscape, October 2016Tracxn
There were 20+ acquisitions in this space in 2016; IBM’s $2.6B acquisition of Truven Analytics, and Affymetrix’s acquisition by Thermo Fisher Scientific for $1.6B were the largest M&A events for the sector this year.
Pfizer strategy for internationalizationAamir chouhan
This document provides an overview of Pfizer, a global pharmaceutical company. It discusses Pfizer's vision, mission, strategic moves, organizational structure, and key financial metrics. Pfizer discovers, develops, and markets prescription medicines for humans and animals. It has grown through acquisitions and partnerships, and restructured in 2014 to focus on innovative pharmaceuticals, vaccines, and consumer healthcare. Pfizer faces challenges from patent expirations and increasing costs of drug development.
DuPont at Bernstein's 31st Annual Strategic Decisions Conference 2015DupontInv
- DuPont is transforming its portfolio to focus on three strategic areas: Agriculture & Nutrition, Advanced Materials, and Bio-Based Industrials, which are large, growing markets aligned with its science capabilities.
- Through acquisitions and divestitures, DuPont has shifted its portfolio mix towards its strategic focus areas and away from less strategic businesses.
- DuPont's transformation strategy of driving operational efficiency, innovation, and growth in developing markets has delivered clear results, including 266% total shareholder return, $9B in annual sales from new products, and a 32% reduction in management headcount.
Wright Medical is a global leader in extremities and biologics that recently merged with Tornier. The presentation discusses how the merger positions Wright Medical for accelerated growth and profitability by combining complementary product portfolios and providing scale. Wright expects mid-teens sales growth, adjusted EBITDA margins approaching 20% in 3-4 years, and $40-45 million in annual cost synergies once integrated. New products like Simpliciti shoulder and Augment bone graft are driving growth above market rates and an upward path for the combined company.
Agility Health is a leading physical rehabilitation services provider with over 150 locations across the US. The presentation provides an overview of Agility Health's business model, growth strategy, and financials. Key points include:
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The document provides an overview of Pfizer Inc., including its business segments, geographic reach, goals, mission/values, history, strategy, external environment analysis, internal environment analysis, and recommendations. It analyzes Pfizer's pharmaceutical, animal health, and corporate/other business segments. Key points include Pfizer operating in over 150 countries, goals of growing in emerging markets and optimizing its patent-protected portfolio, and an analysis of Pfizer's financial performance compared to rivals. One recommendation is for Pfizer to focus on emerging markets like Asia, China, and India.
Genetic Technologies Limited is a diversified molecular diagnostics company developing tools for the prediction and assessment of chronic disease risk to help physicians proactively manage patient health. The Company’s lead products, ‘GeneType for Breast Cancer’ and ‘GeneType for Colorectal Cancer’, are clinically validated risk assessment tests that are first in their class. The Company signed a multi-year distribution agreement for its COVID-19 Risk Test and remains on track to launch its revolutionary Multi-Test, covering up to 70% of mortalities and morbidities, including major oncological, metabolic, and degenerative diseases. Genetic Technologies recent acquisition of EasyDNA has significantly accelerated the Company’s commercialization strategy, providing established revenue streams and direct-to-consumer marketing channels that include 70 websites in 40 countries. Listed on the ASX in 2000 and NASDAQ in 2005, Genetic Technologies has been a leader in the development and commercialization of genetic risk assessment technology for 20 years.
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1. Solutions to Advance Life Science
1
INTRODUCTION AND DISCUSSION MATERIALS
MAY 2014
2. Solutions to Advance Life Science
2
Table of Contents
I. Safe Harbor Statement
II. Introduction to Harvard Bioscience
III. Segments, Brands, Products and Commercial Channels
IV. Financial Data
V. Executive Leadership Team
VI. Appendix
3. Solutions to Advance Life Science
SAFE HARBOR STATEMENT
3
This presentation contains forward-looking statements within the meaning of the federal securities laws. You can identify these statements by our
use of such words as “will,” “guidance,” “objectives,” “optimistic,” “potential,” “future,” “expects,” “plans,” “estimates,” “continue,” “drive,”
“strategy,” “potential,” “potentially,” “growth,” “long-term,” “projects,” “projected,” “intends,” “believes,” “goals,” “sees,” “seek,” “develop”
“possible” “new,” “emerging,” “opportunity,” “pursue” and similar expressions that do not relate to historical matters. Forward-looking statements
in this presentation may include, but are not limited to, statements or inferences about the Company’s or management’s beliefs or expectations, the
Company’s anticipated future revenues and earnings, the strength of the Company’s market position and business model, the impact of acquisitions,
or potential acquisitions, the outlook for the life sciences industry, the Company’s business strategy, the positioning of the Company for growth, the
market demand and opportunity for the Company’s current products, or products it is developing or intends to develop, and the Company’s plans,
objectives and intentions that are not historical facts.
These statements involve known and unknown risks, uncertainties and other factors that may cause the Company’s actual results, performance or
achievements to be materially different from any future results, performance or achievements expressed or implied by the forward-looking
statements. Factors that may cause the Company’s actual results to differ materially from those in the forward-looking statements include economic
and political conditions generally and those affecting pharmaceutical and biotechnology industries, research funding levels from endowments at our
university customers, our financial position, general economic outlook or other circumstances, the Company’s failure to identify potential acquisition
candidates, successfully negotiate favorable pricing and other terms with acquisition candidates to enable potential acquisitions to close, successfully
integrate acquired businesses or technologies, complete consolidations of business functions, expand our product offerings, introduce new products
or commercialize new technologies, unanticipated costs relating to acquisitions, unanticipated costs arising in connection with the Company’s
consolidation of business functions and any restructuring initiatives, decreased demand for the Company’s products due to changes in our
customers’ needs, our ability to obtain regulatory approvals, the seasonal nature of purchasing in Europe, economic, political and other risks
associated with international revenues and operations, including expansion into Asia and other emerging markets, additional costs of complying with
recent changes in regulatory rules applicable to public companies, our ability to manage our growth, our ability to retain key personnel, competition
from our competitors, technological changes resulting in our products becoming obsolete, future changes to the operations or the activities of our
subsidiaries due to manufacturing consolidations, our ability to meet the financial covenants contained in our credit facility, our ability to protect our
intellectual property and operate without infringing on others’ intellectual property, potential costs of any lawsuits to protect or enforce our
intellectual property, impact of any impairment of our goodwill or intangible assets, our ability to utilize deferred tax assets after the release of our
valuation allowances, plus factors described under the heading “Item 1A. Risk Factors” in the Company’s Annual Report on Form 10-K for the
fiscal year ended December 31, 2013 or described in the Company’s other public filings. The Company’s results may also be affected by factors of
which the Company is not currently aware. The Company may not update these forward-looking statements, even though its situation may change in
the future, unless it has obligations under the federal securities laws to update and disclose material developments related to previously disclosed
information.
5. Solutions to Advance Life Science
HISTORY AND OVERVIEW
Harvard Bioscience, Inc. is a Global Developer, Manufacturer, and Marketer of a broad range of specialized
products, primarily apparatus and scientific instruments, used to advance life science research.
Our Clients consist of Universities and Academic Laboratories; Biotechnology Companies; Pharmaceutical
Research; and Government, NIH
Founded in 1901, by Dr. William Townsend Porter, at Harvard University Medical School under the name of
Harvard Apparatus.
In 1996, keeping the Harvard Apparatus Brand, the company underwent a name change and became
Harvard Bioscience, Inc. (HBIO).
In 2000 HBIO became publicly traded on NASDAQ
Harvard Bioscience had a 2013 Annual revenue of $105m, with products sold in over 100 countries.
Corporate Headquarters are located in Holliston, MA.
6. Solutions to Advance Life Science
6
GLOBAL FOOTPRINT
Distribution Ctr
Manufacturing
Sales Office
Corporate Office
7. Solutions to Advance Life Science
RE-ALIGNMENT OF OPERATIONS
Organizational efficiencies were created which have better positioned HBIO for growth
Elimination of operational redundancies;
Global workforce reduction of approximately13%; and
A streamlined and highly functional organization was created enhancing HBIO’s platform for growth.
Re-allocation of resources to higher-growth areas with reinvestment in
China expansion;
Other emerging markets;
Build-up stronger channel capabilities;
Reinvigorate product development; and
Sales and marketing development initiatives.
Overall annual savings of approximately $2 million on a pre-tax basis, includes
$3 million, approximate, reduction in personnel related costs and expenditures;
$1 million to be reinvested.
7
8. Solutions to Advance Life Science
GLOBAL GROWTH STRATEGY
8
Commercial
Excellence /
Organic
Growth
Reinvigorating
Product
Development
Business
Development
/ Acquisitions
Solutions to Advance Life Science
9. Solutions to Advance Life Science
RECENT CATALYSTS
SPIN-OFF
Harvard Apparatus Regenerative Technology (NASDAQ: HART)
Positioning HBIO as a pure-play global developer, manufacturer, and marketer of a broad range of
tools to advance life science research
Building and Securing a highly effective, innovative and experienced Management Team
Focused on global growth strategies
Operations Realignment
Efficiencies, reallocation of resources
Driving a new Global Growth Strategy
Capitalizing on market growth and demand
9
10. Solutions to Advance Life Science
SEGMENTS, BRANDS, PRODUCTS & COMMERCIAL CHANNELS
10
16. Solutions to Advance Life Science
RESENT FINANCIAL PERFORMANCE
Q1 2014 Q4 2013 2013
REVENUES $25.9M (-0.7%) $27.9 million (-1.4%) 105.2 million (-5.4%)
TOTAL NON-GAAP EPS $0.05 (-22%) $0.05 (-44%) $0.22 (-35%)
16
Backlog of $5.6m at March 31, 2014, up 44% over Q1 last year
Three consecutive quarters of growth in backlog
17. Solutions to Advance Life Science
2014 FINANCIAL GUIDANCE
2014 Revenues estimated to remain approximately the same as 2013
Bridge year to return the Company to topline organic growth in 2015
Non-GAAP EPS of $0.26 per diluted share
Anticipated improvement of approximately 20% primarily because of operational
improvements and efficiencies
17
18. Solutions to Advance Life Science
Stock Price $4.17
Market Cap $133m
Shares Outstanding 31.9m
Insider Ownership
(Approximation)
6%
Institutional Ownership
(Approximation)
52%
STOCK INFORMATION
Exchange: NASDAQ
Symbol: HBIO
NOTE:
The numbers provided in this presentation are based on market close 5/2/2014
19. Solutions to Advance Life Science
INVESTMENT HIGHLIGHTS
HBIO is a well established company with several growth catalysts and business
opportunities.
The Newly formed Executive Leadership Team brings extensive experience to the
organization.
Focus on growth opportunities / Global expansion within China and other emerging
markets.
Re-alignment of operational efficiencies.
Multiple distribution channels provides for increased sales opportunities, distinguishes
HBIO from other industry peers.
19
21. Solutions to Advance Life Science
EXECUTIVE LEADERSHIP
21
Jeffrey A. Duchemin
President and CEO
Prior to joining HBIO, as President and CEO, Mr. Duchemin held the role of Global Business
Director at Corning Life Sciences (NYSE: GLW) .
Preceding Corning, and for sixteen-years, he held progressive sales, marketing and executive
leadership positions at Becton Dickinson (NYSE: BDX).
Robert E. Gagnon
Chief Financial Officer
Before joining the new Executive Leadership Team Mr. Gagnon was CFO at Clean Harbors, Inc.
(NYSE: CLH). Prior to Clean Harbors, he held progressive leadership positions with Biogen Idec,
Inc. (NASDAQ: BIIB)
22. Solutions to Advance Life Science
EXECUTIVE LEADERSHIP
22
Ronald D. Aplin
VP Global Operations & Quality
Ron Aplin VP of Global Operations and Quality, joined HBIO in March, 2014, and is formerly from Becton
Dickinson (NYSE: BDX) where he held the role of Director of Operations; Plant Manager for Teleflex.
Prior to Beckton Dickinson Ron worked for Corning Life Sciences (NYSE: GLW) as Operations/Plant Manager.
Yoav Sibony
VP Global Sales
Yoav Sibony, Vice President Global Sales, brings extensive sales and management experience from Corning
Life Sciences (NYSE: GLW), and his previous roles as Global Sales Effectiveness Manager; and Global Business
Operations and Strategy Development.
Prior to Corning, Yoav held ten-years of progressive positions with Becton Dickinson (NYSE: BDX).
Yong Sun, Formerly of Beaver-Visitec International, VP of Global Marketing and Americas Sales, joined HBIO’s
Executive Leadership as VP Global Strategic Marketing, Business Development; and R&D.
Yong Sun also held positions at Becton Dickinson, as Director of Global Marketing & U.S. Sales, as well as Eli
Lilly- Marketing Manager, Global Life Sciences Market.Yong Sun
VP Global Strategic Marketing,
Business Development; and R&D
24. Solutions to Advance Life Science
24
EXHIBIT 6
HARVARD BIOSCIENCE, INC.
Reconciliation of GAAP Diluted Earnings Per Common Share from Continuing Operations to Non-GAAP Adjusted
Diluted Earnings Per Common Share from Continuing Operations
(unaudited)
THREE MONTHS ENDED
DECEMBER 31
YEAR END
DECEMBER 31
THREE MONTHS ENDED
MARCH 31
2013 2013 2013 2014
GAAP diluted earnings per common share from continuing operations $ (0.01) $ 0.02 $ 0.02 $ 0.03
ADJUSTMENTS:
Amortization of Intangible Assets 0.02 0.08
Acquisition Costs - - -
HART transaction costs 0.01 0.06 - 0.02
Severance and restructuring charges 0.07 0.07 0.01 -
Stock-based compensation expense 0.02 0.08 0.01 0.02
Income taxes (A) (0.06) (0.09) (0.01) (0.02)
Non-GAAP adjusted diluted earnings per common share from
continuing operations $ 0.05 $ 0.22 $ 0.05 $ 0.07
(A) Income taxes includes the tax effect of adjusting for the reconciling items.
25. Solutions to Advance Life Science
25
HARVARD BIOSCIENCE, INC.
Reconciliation of Guidance for 2014 GAAP Diluted Earnings per Common Share to Non-GAAP Adjusted Diluted
Earnings per Common Share
(unaudited)
GAAP diluted earnings per common share from continuing operations (A) $ 0.14
ADJUSTMENTS:
Amortization of intangible assets 0.07
Severance and restructuring charges 0.01
Stock-based compensation expense 0.09
Income taxes (B) (0.5)
Non-GAAP adjusted diluted earnings per common share from continuing operations (A) $ 0.26
(A) This guidance excludes the impact of future acquisitions, acquisition costs or restructuring charges.
(B) Income taxes includes the tax effect of adjusting for the reconciling items.