Graham Cope                                                                                                                                  European Investment
European Investment Fund                                                                                                                                Fund




         EIF support of Tech Transfer and Intellectual Property
                    And how we want to do more
         This presentation was prepared by EIF. Any estimates and projections contained herein involve significant elements of subjective judgment and analysis, which may or may not be correct.
€5.4bn Net Equity Commitments




                                                                               Venture & Growth Capital Portfolio
            across Europe at 31.12.2010
            EUR m
                                                         Lithuania 40
            Austria 54                                   Luxembourg 21
            Belgium 82                                   Malta 8
            Bulgaria 13                                  Netherlands 109
            Cyprus 7                                     Norway 25
            Czech Republic 28                            Poland 92
            Denmark 95                                   Portugal 155
            Estonia 7                                    Romania 36
            Finland 115                                  Slovakia 4
            France 768                                   Spain 423
            Germany 558                                  Sweden 280
            Greece 15                                    Switzerland 81
            Hungary 16                                   Turkey 274
            Ireland 89                                   United Kingdom 1306
            Italy 267                                    Other & Non EU 396
            Latvia 36



 Nordic
 Region
 (total):
EUR 515m




                                EU 27
                                EU Candidate Countries
1                               EFTA/EEA
Technology Transfer - Converting Research
             into Products for the Market

       R&D                    Technology Transfer           Marketable Product
                                “technology IP”             “prototype IP”

    University /                                                Market
     Research                        Spin-out
    Organisation

                                     Licensing


     IP / Idea
                                  Collaboration
                               (contract research,…)


                 Technology Transfer is the process which uses these 3
                 channels to convert scientific findings from research
                 organisations into commercial products
2
ElF's Tech Transfer Experience

     Since 2005, EIF has been able to invest more and
       more resources to understand Tech Transfer, to create
       awareness and to develop new TT initiatives with
       leading research universities
     Focus is on research organisations which are leaders in
      their respective fields and act in an entrepreneurial
      environment
     Accelerated process through framework agreements
      (covering issues such as company valuations,
      shareholder structure,…)
     Several transactions already, in which EIF played a key
      role
     Eager to do more…


3
EIF Tech Transfer Transactions
                                                                                  Karolinska Development
                                       Chalmers Innovation                        • EUR 26.7 m
                                       • SEK 170 m                                • Signed Nov 2009
                                       • Signed July 2008                         • Co-investment fund, investing
                                       • Investing in start-up companies            alongside Karolinksa
                                         originating from Chalmers                  Development in life science
                                         University and incubated by the            spin-outs throughout
                                         Chalmers Innovation incubator              Scandinavia
                                         in Gothenburg

UMIP Premier Fund
                                                                                                     Imprimatur (JEREMIE: development
• GBP 32m fund
                                                                                                       objective)
• Signed April 2008
                                                                                                     ongoing transaction
• Fund, managed by MTI, invests
                                                                                                     • EUR 20,4m
  in university spin-outs
                                                                                                     • Expected Signature 2010
  originating from the University of
                                                                                                     • Seed & Start-Ups / Tech Transfer
  Manchester
                                                                                                       in Latvia
                                                                                                     • Fund to be managed by the
IP venture fund UK                                                                                     local Imprimatur team in Riga
• GBP 31m fund
• Signed September 2006
• Fund invests 25% of all
   financing rounds of IP group                  Leuven CD3 (Centre for
   spinouts, originating from more               Drug Design and Discovery)
   than 10 UK universities                       • EUR 24m fund
                                                 • Signed Mid 2006
                                                 • Financing early stage drug
                                                    development projects
                                                    originating from Leuven and
   4
                                                    elsewhere in EU
Manchester the Largest UK University
                 Research Budget


Manchester University / UMIP Premier Fund

                                            ■ 10 year Limited Partnership.
                                            ■ Managed by VC firm: MTI partners
                                            ■ GBP 32 m raised. 18 months between
                                              first pitch to EIF and first closing in
                                              4/2008




5
IP Group: Bringing together 10 Universities
              - 74 Spin-outs in 3 years


    IP Venture Fund UK                       ■ Co-investment fund (seed,
                                               post-seed financing
                                             ■ Critical mass reached
                                               through a network of
                                               universities
                                             ■ Liquidity vs listing




                                                   Deal flow and
                                                    critical mass




6
Case Study: Chalmers Innovation
                      Starting point: a proven tech transfer
                      and incubation process, creating approx.
                      10 start-ups per year

                     Process steps

                             Pre-Incubation         Incubation           “Alumni”
          Start-up                                                       companies
          projects

                                ~6m                     24-36m
       Milestone      Entrepreneurial mind    Formed company       Repetitive business
    / Deliverable     Large potential         Validated business   Developed organisation
                      Unique idea             CEO                  Board of directors
                      Control of IPR          Business plan        Secured longer term
                      Technology based        Financial plan       finance




7
Case Study: Chalmers Innovation
                       The fund, managed by an enlarged
                       incubator team, invests in all steps
                       of the process

                                               EIF                 Co-investors


                                                   “Fund”                               Seed Investors
       Management team                   •Investments at commercial terms
                                                                                  Federal funds
       •Incubator professionals          •Investments in existing TTO start-ups
                                                                                     Regional funds
        (industrial background)           and new start-ups (both university IP
                                                                                       Other public/private funds
       •Investment professionals          based spin-outs as well as start-ups
                                          attracted and grown by the                       BAs, VCs, …
       •Maximum autonomy
                                          incubator)




                              “Pre-seed funding”            “Seed funding”          “Post-seed funding”
                              Pre-Incubation                    Incubation               Alumni companies
    Tech Transfer process


               Indicative     EUR ~50k                      EUR 200-500k            EUR 1-3m
                amounts
8
Case Study: Chalmers Innovation
      Investment case for EIF

     Size and quality of deal flow
         The university generates an important flow of
           innovations
         The region is a well functioning entrepreneurial
           ecosystem

     The TTO delivers
         Breadth and depth of team
         Track-record in developing start-ups
         Invests before and at company creation
     Potential to have a significant impact
         Develop start-ups better and faster
         Capture a larger share of the value created

9
Lessons Learnt 5 Years on

      Clear funding gap persists
      Tech Transfer is different to VC and has its own set of rules
      Not just spin-outs in the story but also licensing
      Long-term partnerships with research centres: build trust,
        no individual entry valuations, ex ante agreements, no
        dilution -- Privileged access to deal flow and “Bears’ hug”
      Increasing interest from private co-investors but still room
        for improvement
      Longer time-horizon for business development and lead-
        time
      Growing policy-maker focus


10
Knowledge Transfer Strategic Partnership
            First initiative to address challenges and widen the reach and scope
Partners
            Signed in Rome - 16 June 2010
            Creation of joint Working Group between EIF/EIB, CDC (France),
             (CDP – Italy), (CDTI - Spain), Innovationsbron (Sweden), KfW-
             Bankengruppe (Germany) & Veraventures (Finland)
            Aim of like-minded Partners is to:
               Support the emergence of European and national Knowledge
                Transfer Infrastructures
                Accelerate transfer of European research and technology to the
                 market
                Facilitate a well functioning Knowledge Transfer and Intellectual
                 Property economy
                Encourage more open and transparent marketplaces for
                 Intellectual Property
                Exchange best practices and potentially to analyse investment
                 opportunities jointly

11
The Growing Importance of Fund-of-Funds management
                      (selected examples)



                      ERP (launched in 2004)
                         Co-investment 50/50: EIF/ERP (administered by German Ministry BMWi)
                           Size: € 1bn - € 642m committed in 20 funds
     Copyright ERP    NEOTEC: Spanish Technology Fund-of-Funds (launched in 2006)
                         Tech fund in partnership with CDTI (TMT, ICT, cleantech, biotech and LS)
                           Size: € 183m - € 117m in 11 Funds and Co-investment Agreements

                      Istanbul Venture Capital Initiative (launched in 2007)
                         Turkish generalist VC investment vehicle for institutional investors
                           Size: € 160m - 2 funds signed for a total of € 21m

                      Portuguese Venture Capital Initiative (launched in 2008)
                         Generalists funds, ICT, Life Sciences, Healthcare, Environmental &
                         Energy Technology
                           Size: € 111m – 2 transactions signed for a total of € 30m
                      UKFTF: UK technology Fund-of-Funds (launched in 2010)
                         Launched by the UK government and advised by EIF
                           Size: £200m at first closing to be invested in Funds targeting UK
                            start-ups and growth businesses in the high tech sector –
                            3 investments signed for £28m


12                         Public Private Leveraging of EIF Capacity and Experience
How do we see the Nordic market?

     Many strengths                Worrying weaknesses
      High Quality University &     Difficult market conditions
        Research Institutions          to attract private investors
      Mature Market with            Withdrawal of certain
        experienced investment
        professionals                  fund managers

      Track records and             Withdrawal of certain
        Success stories                Pension Funds
      High cross-border             Global competition for
        collaborations levels          investment flows
      Strong entrepreneurial        Talent loss
        environment
                                     Missed opportunities
      Many investment
        opportunities

13
Contacts

     European Investment Fund
     96 boulevard Konrad Adenauer
     L-2968 Luxembourg
     Tel.: (+352) 42 66 881
     Fax: (+352) 42 66 88 200
     www.eif.org
     Jacques Darcy, Head of Technology Transfer & Intellectual
     Property – j.darcy@eif.org
     Graham Cope, Head of Region, Northern Europe Business
     Development – g.cope@eif.org



14

EIF Support of Tech Transfer and Intellectual Property - And how we want to do more

  • 1.
    Graham Cope European Investment European Investment Fund Fund EIF support of Tech Transfer and Intellectual Property And how we want to do more This presentation was prepared by EIF. Any estimates and projections contained herein involve significant elements of subjective judgment and analysis, which may or may not be correct.
  • 2.
    €5.4bn Net EquityCommitments Venture & Growth Capital Portfolio across Europe at 31.12.2010 EUR m Lithuania 40 Austria 54 Luxembourg 21 Belgium 82 Malta 8 Bulgaria 13 Netherlands 109 Cyprus 7 Norway 25 Czech Republic 28 Poland 92 Denmark 95 Portugal 155 Estonia 7 Romania 36 Finland 115 Slovakia 4 France 768 Spain 423 Germany 558 Sweden 280 Greece 15 Switzerland 81 Hungary 16 Turkey 274 Ireland 89 United Kingdom 1306 Italy 267 Other & Non EU 396 Latvia 36 Nordic Region (total): EUR 515m EU 27 EU Candidate Countries 1 EFTA/EEA
  • 3.
    Technology Transfer -Converting Research into Products for the Market R&D Technology Transfer Marketable Product “technology IP” “prototype IP” University / Market Research Spin-out Organisation Licensing IP / Idea Collaboration (contract research,…) Technology Transfer is the process which uses these 3 channels to convert scientific findings from research organisations into commercial products 2
  • 4.
    ElF's Tech TransferExperience  Since 2005, EIF has been able to invest more and more resources to understand Tech Transfer, to create awareness and to develop new TT initiatives with leading research universities  Focus is on research organisations which are leaders in their respective fields and act in an entrepreneurial environment  Accelerated process through framework agreements (covering issues such as company valuations, shareholder structure,…)  Several transactions already, in which EIF played a key role  Eager to do more… 3
  • 5.
    EIF Tech TransferTransactions Karolinska Development Chalmers Innovation • EUR 26.7 m • SEK 170 m • Signed Nov 2009 • Signed July 2008 • Co-investment fund, investing • Investing in start-up companies alongside Karolinksa originating from Chalmers Development in life science University and incubated by the spin-outs throughout Chalmers Innovation incubator Scandinavia in Gothenburg UMIP Premier Fund Imprimatur (JEREMIE: development • GBP 32m fund objective) • Signed April 2008 ongoing transaction • Fund, managed by MTI, invests • EUR 20,4m in university spin-outs • Expected Signature 2010 originating from the University of • Seed & Start-Ups / Tech Transfer Manchester in Latvia • Fund to be managed by the IP venture fund UK local Imprimatur team in Riga • GBP 31m fund • Signed September 2006 • Fund invests 25% of all financing rounds of IP group Leuven CD3 (Centre for spinouts, originating from more Drug Design and Discovery) than 10 UK universities • EUR 24m fund • Signed Mid 2006 • Financing early stage drug development projects originating from Leuven and 4 elsewhere in EU
  • 6.
    Manchester the LargestUK University Research Budget Manchester University / UMIP Premier Fund ■ 10 year Limited Partnership. ■ Managed by VC firm: MTI partners ■ GBP 32 m raised. 18 months between first pitch to EIF and first closing in 4/2008 5
  • 7.
    IP Group: Bringingtogether 10 Universities - 74 Spin-outs in 3 years IP Venture Fund UK ■ Co-investment fund (seed, post-seed financing ■ Critical mass reached through a network of universities ■ Liquidity vs listing Deal flow and critical mass 6
  • 8.
    Case Study: ChalmersInnovation Starting point: a proven tech transfer and incubation process, creating approx. 10 start-ups per year Process steps Pre-Incubation Incubation “Alumni” Start-up companies projects ~6m 24-36m Milestone Entrepreneurial mind Formed company Repetitive business / Deliverable Large potential Validated business Developed organisation Unique idea CEO Board of directors Control of IPR Business plan Secured longer term Technology based Financial plan finance 7
  • 9.
    Case Study: ChalmersInnovation The fund, managed by an enlarged incubator team, invests in all steps of the process EIF Co-investors “Fund” Seed Investors Management team •Investments at commercial terms Federal funds •Incubator professionals •Investments in existing TTO start-ups Regional funds (industrial background) and new start-ups (both university IP Other public/private funds •Investment professionals based spin-outs as well as start-ups attracted and grown by the BAs, VCs, … •Maximum autonomy incubator) “Pre-seed funding” “Seed funding” “Post-seed funding” Pre-Incubation Incubation Alumni companies Tech Transfer process Indicative EUR ~50k EUR 200-500k EUR 1-3m amounts 8
  • 10.
    Case Study: ChalmersInnovation Investment case for EIF  Size and quality of deal flow  The university generates an important flow of innovations  The region is a well functioning entrepreneurial ecosystem  The TTO delivers  Breadth and depth of team  Track-record in developing start-ups  Invests before and at company creation  Potential to have a significant impact  Develop start-ups better and faster  Capture a larger share of the value created 9
  • 11.
    Lessons Learnt 5Years on  Clear funding gap persists  Tech Transfer is different to VC and has its own set of rules  Not just spin-outs in the story but also licensing  Long-term partnerships with research centres: build trust, no individual entry valuations, ex ante agreements, no dilution -- Privileged access to deal flow and “Bears’ hug”  Increasing interest from private co-investors but still room for improvement  Longer time-horizon for business development and lead- time  Growing policy-maker focus 10
  • 12.
    Knowledge Transfer StrategicPartnership  First initiative to address challenges and widen the reach and scope Partners  Signed in Rome - 16 June 2010  Creation of joint Working Group between EIF/EIB, CDC (France), (CDP – Italy), (CDTI - Spain), Innovationsbron (Sweden), KfW- Bankengruppe (Germany) & Veraventures (Finland)  Aim of like-minded Partners is to:  Support the emergence of European and national Knowledge Transfer Infrastructures  Accelerate transfer of European research and technology to the market  Facilitate a well functioning Knowledge Transfer and Intellectual Property economy  Encourage more open and transparent marketplaces for Intellectual Property  Exchange best practices and potentially to analyse investment opportunities jointly 11
  • 13.
    The Growing Importanceof Fund-of-Funds management (selected examples)  ERP (launched in 2004) Co-investment 50/50: EIF/ERP (administered by German Ministry BMWi)  Size: € 1bn - € 642m committed in 20 funds Copyright ERP  NEOTEC: Spanish Technology Fund-of-Funds (launched in 2006) Tech fund in partnership with CDTI (TMT, ICT, cleantech, biotech and LS)  Size: € 183m - € 117m in 11 Funds and Co-investment Agreements  Istanbul Venture Capital Initiative (launched in 2007) Turkish generalist VC investment vehicle for institutional investors  Size: € 160m - 2 funds signed for a total of € 21m  Portuguese Venture Capital Initiative (launched in 2008) Generalists funds, ICT, Life Sciences, Healthcare, Environmental & Energy Technology  Size: € 111m – 2 transactions signed for a total of € 30m  UKFTF: UK technology Fund-of-Funds (launched in 2010) Launched by the UK government and advised by EIF  Size: £200m at first closing to be invested in Funds targeting UK start-ups and growth businesses in the high tech sector – 3 investments signed for £28m 12 Public Private Leveraging of EIF Capacity and Experience
  • 14.
    How do wesee the Nordic market? Many strengths Worrying weaknesses  High Quality University &  Difficult market conditions Research Institutions to attract private investors  Mature Market with  Withdrawal of certain experienced investment professionals fund managers  Track records and  Withdrawal of certain Success stories Pension Funds  High cross-border  Global competition for collaborations levels investment flows  Strong entrepreneurial  Talent loss environment  Missed opportunities  Many investment opportunities 13
  • 15.
    Contacts European Investment Fund 96 boulevard Konrad Adenauer L-2968 Luxembourg Tel.: (+352) 42 66 881 Fax: (+352) 42 66 88 200 www.eif.org Jacques Darcy, Head of Technology Transfer & Intellectual Property – j.darcy@eif.org Graham Cope, Head of Region, Northern Europe Business Development – g.cope@eif.org 14