2. GENERALITIES
EXTREMELY PAINFUL EPISODES
OF ARTHRITIS
INTERMITTENT COURSE,
USUALLY MONOARTICULAR IN
VOLVING THE BIG TOE, ANKLE,
KNEE
MAY LATER BE OLIGO-
OR POLYARTICULAR
TENDENCY TO ABUSE NSAIDS
(AND STEROIDS)
MAY BE PRECIPITATED BY
STRESS E.G SURGERY, BLOOD
TRANSFUSION
3. Gouty Arthritis: Clinical
Presentation
• Precipitated by local
trauma unaccustomed exercise
& alcohol consumption
• Excruciating pain over
hours frequently nocturnal
8. Intercritical Gout
Asymptomatic phase or intervals between attacks
of gouty arthritis. A patient who
has intercritical gout simply has gout that has
caused attacks of inflammation in a joint in the
past, but it is not visibly active at the time the
doctor is evaluating the patient.
11. Tophi
Tophi are clumps of urate
crystals that harden under your
skin. They can form on most joints
and cartilage including your
fingers, hands, feet, and/or ankles.
Tophi also commonly form on the
ears. Tophi may not cause pain,
but can damage your joints,
bones, and cartilage if left
untreated.
12.
13. Joint Damage and
Deformity
When you have chronic gout, you
have swelling in your joints
regularly. Chronic inflammation
and tophi can lead to permanent
joint damage, deformity, and
stiffness. In the worst cases of
chronic gout, you may need
surgery to fix joint damage, or
replace joints.
14. Kidney Stones
You are at risk for getting kidney stones
when you have gout, since urate crystals
can build up in your urinary tract and form
stones.
15. Kidney Disease and
Kidney Failure
Kidney stones made from urate
crystals can build up in your
kidneys, and can cause damage
and scars. This kidney
damage from urate crystals is
thought to lead to kidney disease
over time, especially if gout is left
untreated and may lead to
hemodialysis.