This document describes an anti-aging supplement that works while sleeping to reduce signs of aging. It contains hydrolyzed collagen, hyaluronic acid, and grape seed extract to reduce wrinkles by 23-40%, improve skin suppleness by 19%, and increase hydration by 28%. The ingredients are digested into smaller particles that stimulate fibroblast cells to increase collagen formation and regulate collagen structure for firmer, more youthful skin. The supplement is taken as tablets before bed or mixed into a beverage daily for anti-aging benefits.

2. Skin that defies time
Range of
Anti-ageing
supplements
and face
creams
ultimate experience ‘at home’
Defy works while sleeping
Removes the marks of age and
make the skin shiner

3. Indications
Dull and lifeless skin
Sagged and aged skin
Fine and deep wrinkles
Post Botox and fillers.
Dehydrated skin
Prevention of wrinkles
Part of Daily skin care regimen

4. Composition
Hydrolyzed collagen
High amino acid profile
Hyaluronic acid
Grape seed extract

5. Effects
Reduce wrinkles (depth &
length)
Improve skin suppleness
Prevent deep wrinkles

6. Clinical studies :
Wrinkle Reduction
Double blind of 47 volunteers (age
35-55 years old women), normal to
dry skin placebo controlled trial in
reducing wrinkles for 12 weeks
(using Cutometer MPA 850).
Dermscan Laboratories, France,
2008 (Study 2008-A00654)
Reduction of 23% in the depth and
40% in the width of the wrinkles
The number of deep wrinkles
significantly increases with the placebo
between baseline and week 12: +30%.

7. Clinical studies :
Skin suppleness
Double blind of 47 volunteers
(age 35-55 years old women),
normal to dry skin placebo
controlled trial in increasing skin
suppleness for 12 weeks (using
Cutometer MPA 850).
Souken, Tokyo, Japan, 2008
(Study YNTKK - 2008 - 4144)
The number of micro-relief furrows
significantly decreases: -26% at 12 weeks
The skin suppleness increases by 19%

8. Clinical studies :
Hydration
Double blind of 33 volunteers
(age 40-59 years old), normal
to dry skin placebo controlled
trial in improving skin
hydration for 8 weeks (using
Corneometer CM 825).
28% increase in degree of skin
hydration in 91% of the group.

9. Mechanism of Action
The components digested (90%)
by Proteolytic enzymes
(Collagenase) to smaller
bioavailable particles
Distributed through the blood
circulation and then to the body
tissues ( 12 hours)
Formation of peptides Chemo-
attractants for fibroblasts leads to
trigger of new collagen formation
Stimulation of fibroblast cells &
increase in fibroblast density &
increase diameter of collagen
fibrile
Increase the decorin ratio interact
with collagen, influences collagen
fibrillo genesis & regulates
excessive bundle-like aggregation
of collagen

10. Use
Drink two tablets
once daily at
bedtime followed by
a full glass of water.
Every evening after
cleansing, massage a
thin layer evenly
over face and neck.
Dissolve a scoop of
powder into water,
milk or juice daily.