Global Digital Biomarkers Market

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April 2022
Global Digital
Biomarkers
Market - A Global
and Regional
Analysis
Focus on System Component, Type,
Application, End User, Regional and
Country-Wise Analysis
Analysis and Forecast:2022-2028
Table of Content

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Table of Content
Executive Summary....................................................................................30
Scope of the Study .....................................................................................39
Research Methodology ..............................................................................41
1. Markets.................................................................................................47
1.1 Market Outlook.................................................................................................47
1.1.1 Product Definition .......................................................................................47
1.1.1.1 Data Collection Tools......................................................................................... 47
1.1.1.1.1 Wearable Devices ................................................................................................... 47
1.1.1.1.2 Implantables............................................................................................................ 47
1.1.1.1.3 Mobile Applications ................................................................................................ 48
1.1.1.2 Data Integration Software.................................................................................. 48
1.1.2 Inclusion and Exclusion Criteria................................................................48
1.1.3 Key Findings................................................................................................49
1.1.4 Global Market Scenario...............................................................................49
1.1.4.1 Realistic Growth Scenario ................................................................................. 49
1.1.4.2 Optimistic Growth Scenario ............................................................................... 50
1.1.4.3 Pessimistic/Conservative Growth Scenario ....................................................... 51
1.2 Global Digital Biomarkers Market Overview..................................................52
1.2.1 Current State of Digital Biomarker.............................................................52
1.2.2 Types of Biomarkers...................................................................................53
1.2.2.1 Wellness ............................................................................................................ 53
1.2.2.2 Disease.............................................................................................................. 53
1.2.2.3 Drugs ................................................................................................................. 53
1.2.3 Industry ........................................................................................................54
1.2.3.1 Pharmaceutical.................................................................................................. 54
1.2.3.2 Biotechnology/Life Sciences.............................................................................. 54
1.2.3.3 Medical Devices................................................................................................. 55
1.2.3.4 Application Vendors........................................................................................... 55
1.2.4 Clinical Trials (Clinical Research Organization) .......................................55

1.2.4.1 Technology Vendors.......................................................................................... 56
1.2.5 Digital Biomarker Ecosystem.....................................................................56
1.2.5.1 Wearable Devices.............................................................................................. 57
1.2.5.2 Implantable Components/ Sensors.................................................................... 59
1.2.5.3 Ocular Devices .................................................................................................. 59
1.2.5.4 Accelerometers.................................................................................................. 60
1.2.5.5 Smart Home Systems/IoTs................................................................................ 60
1.2.5.6 AR/VR Platforms................................................................................................ 60
1.2.5.7 Desktop/Web Applications................................................................................. 61
1.2.6 Data Measurement.......................................................................................61
1.2.6.1 Physiological Parameters .................................................................................. 61
1.2.6.2 Behavioral Parameters ...................................................................................... 61
1.3 Industry Outlook..............................................................................................62
1.3.1 Technology Landscape...............................................................................62
1.3.1.1 Artificial Intelligence and Machine Learning ...................................................... 62
1.3.1.2 Augmented Reality (AR) and Virtual Reality (VR) ............................................. 63
1.3.1.3 Blockchain ......................................................................................................... 63
1.3.1.4 Edge Computing................................................................................................ 64
1.3.1.5 Cloud Computing............................................................................................... 64
1.3.2 Key Trends...................................................................................................65
1.3.3 Opportunity Assessment............................................................................66
1.3.3.1 Short-Term Growth Potential............................................................................. 66
1.3.3.2 Long-Term Growth Potential.............................................................................. 67
1.3.4 Product Benchmarking...............................................................................67
1.3.5 Patent Analysis............................................................................................68
1.3.5.1 Awaited Technological Developments............................................................... 68
1.3.5.2 Patent Publication Growth Trend....................................................................... 69
1.3.5.3 Patent Analysis (by Country/Cluster)................................................................. 70
1.3.6 Case Studies: Key Therapeutic Areas.......................................................70
1.3.6.1 Cardiovascular Diseases................................................................................... 70

1.3.6.2 Parkinson’s Diseases ........................................................................................ 71
1.3.6.3 Alzheimer’s Diseases ........................................................................................ 72
1.4 Impact of COVID-19 .........................................................................................72
1.4.1 Impact on Digital Biomarkers.....................................................................72
1.4.2 Impact on Device Adoption ........................................................................74
1.4.3 Impact on Market Size.................................................................................77
1.4.3.1 Pre-COVID-19 Phase ........................................................................................ 77
1.4.3.1.1 Global and Regional Analysis.................................................................................. 77
1.4.3.2 During COVID-19 Phase ................................................................................... 79
1.4.3.2.1 Global and Regional Analysis.................................................................................. 79
1.4.3.3 Post-COVID-19 Phase....................................................................................... 81
1.5 Business Dynamics.........................................................................................81
1.5.1 Impact Analysis ...........................................................................................81
1.5.2 Business Drivers .........................................................................................82
1.5.2.1 Rising Popularity of Digital Biomarkers in Drug Development........................... 82
1.5.2.2 Rising Employment of Vocal Digital Biomarkers................................................ 83
1.5.2.3 Rising Use of Wearable Devices and Increasing Smartphone Penetration....... 83
1.5.2.4 Regulatory Flexibility toward Digital Health Solutions........................................ 85
1.5.2.5 Failure of Drugs for Neurodegenerative Disorders ............................................ 85
1.5.3 Business Challenges ..................................................................................86
1.5.3.1 Need for Standardized and Interoperable Solutions.......................................... 86
1.5.3.2 Inaccuracy in Data Measurements .................................................................... 88
1.5.3.3 Lack of Integration and Interoperability between Medical Records and
User Generated Data......................................................................................... 88
1.5.3.4 Lack of Use Cases of the Return on Investment (ROI) Analysis ....................... 88
1.5.4 Business Opportunities..............................................................................89
1.5.4.1 Digital Biomarkers: The Future of Precision Medicine....................................... 89
1.5.4.2 Early Detection of Neurological Disorders Using Digital Biomarkers................. 89
1.5.4.3 Increasing Awareness for General Health Management ................................... 90
1.5.4.4 Upsurge in Demand of Metabolic, Cardiovascular, and Gastrointestinal
Healthcare ......................................................................................................... 90

1.5.4.5 Penetration of Digital Biomarkers in Female, Maternal, Pre- and Neo-
Natal Care.......................................................................................................... 91
1.5.4.6 Rise in Usage of Digital Biomarkers to Assess Pulmonary Health .................... 92
2. Global Digital Biomarker Market (by Application)............................93
2.1 Opportunity Assessment ................................................................................93
2.2 Growth-Share Matrix .......................................................................................95
2.3 Gastrointestinal Diseases...............................................................................96
2.4 Sleep and Movement Disorders ...................................................................100
2.5 Cardiovascular...............................................................................................102
2.6 Psychiatric Disorders (Mood and Behavior) ...............................................105
2.7 Chronic Pain...................................................................................................107
2.8 Neurodegenerative Diseases........................................................................109
2.9 Diabetes..........................................................................................................112
2.10 Respiratory Diseases ....................................................................................114
2.11 Others .............................................................................................................116
3. Global Digital Biomarkers Market (by End User)............................117
3.1 Opportunity Assessment ..............................................................................117
3.2 Growth-Share Matrix .....................................................................................118
3.3 Biopharmaceutical Companies ....................................................................119
3.4 Payers.............................................................................................................120
3.5 Providers ........................................................................................................121
4. Global Digital Biomarkers Market (by System Components)........123
4.2 Market Share Analysis ..................................................................................124
4.4 Data Collection Tools ....................................................................................126
4.4.1 Wearables Devices....................................................................................126
4.4.1.1 Evolution of Wearable Devices in Clinical Trials.............................................. 128
4.4.1.2 Wearable Devices in Clinical Trials ................................................................. 128
4.4.1.3 Actigraphy Devices.......................................................................................... 129

4.4.1.4 Opportunity in Digital Biomarker...................................................................... 130
4.4.1.5 New Developments.......................................................................................... 131
4.4.1.6 Market Estimation and Forecast...................................................................... 131
4.4.2 Implantables ..............................................................................................132
4.4.2.1 Opportunity in Digital Biomarker...................................................................... 132
4.4.3 Mobile Applications...................................................................................134
4.4.3.1 Opportunity in Digital Biomarkers .................................................................... 135
4.5 Data Integration Software .............................................................................137
4.5.1 Opportunity in Digital Biomarker .............................................................139
4.5.2 New Developments....................................................................................139
4.5.3 Market Estimation and Forecast ..............................................................139
5. Global Digital Biomarkers Market (by Type) ...................................140
5.2 Market Share Analysis ..................................................................................141
5.4 Clinical Trials .................................................................................................143
5.5 Clinical Settings.............................................................................................144
6. Region ................................................................................................145
6.1 North America Digital Biomarkers Market...................................................145
6.1.1 Regulatory Framework..............................................................................145
6.1.2 Opportunity Assessment..........................................................................146
6.1.3 Market Dynamics.......................................................................................146
6.1.3.1 Impact Analysis................................................................................................ 147
6.1.4 Sizing and Forecast Analysis...................................................................147
6.1.4.1 North America Digital Biomarkers Market (by Application).............................. 148
6.1.4.2 North America Digital Biomarkers Market (by Type) ....................................... 149

6.1.5 North America Digital Biomarkers Market (by Country) ........................150
6.1.5.1 U.S................................................................................................................... 150
6.1.5.1.1 Digital Health Scenario .......................................................................................... 150
6.1.5.1.2 Degree of Adoption of Wearables.......................................................................... 150
6.1.5.1.3 Degree of Adoption of Mobile Health Applications ................................................ 151
6.1.5.1.4 Local Players in the Digital Biomarker Market....................................................... 151
6.1.5.1.5 U.S. Digital Biomarkers Market.............................................................................. 151
6.1.5.1.6 U.S. Digital Biomarkers Market (by Type) ............................................................. 152
6.1.5.1.7 U.S. Digital Biomarkers Market (by Application).................................................... 153
6.1.5.2 Canada ............................................................................................................ 153
6.1.5.2.5 Canada Digital Biomarkers Market ........................................................................ 155
6.1.5.2.6 Canada Digital Biomarkers Market (by Type)........................................................ 156
6.1.5.2.7 Canada Digital Biomarkers Market (by Application) .............................................. 156
6.2 Europe Digital Biomarkers Market ...............................................................157
6.2.3 Market Dynamics.......................................................................................159
6.2.3.1 Impact Analysis................................................................................................ 160
6.2.4.1 Europe Digital Biomarkers Market (by Application) ......................................... 161
6.2.4.2 Europe Digital Biomarkers Market (by Type)................................................... 162
6.2.5 Europe Digital Biomarkers Market (by Country).....................................163
6.2.5.1 Netherlands ..................................................................................................... 163

6.2.5.1.5 Netherlands Digital Biomarkers Market ................................................................. 164
6.2.5.1.6 Netherlands Digital Biomarkers Market (by Type)................................................. 165
6.2.5.1.7 Netherlands Digital Biomarkers Market (by Application) ....................................... 165
6.2.5.2 Germany.......................................................................................................... 166
6.2.5.2.3 Reluctance to Fitness Trackers ............................................................................. 167
6.2.5.2.4 Future of Digital Health in Germany....................................................................... 167
6.2.5.2.5 Germany Digital Biomarkers Market...................................................................... 168
6.2.5.2.6 Germany Digital Biomarkers Market (by Type)...................................................... 168
6.2.5.2.7 Germany Digital Biomarkers Market (by Application)............................................ 169
6.2.5.3 France.............................................................................................................. 170
6.2.5.3.3 Local Players in Digital Biomarkers Market ........................................................... 170
6.2.5.3.4 France Digital Biomarkers Market.......................................................................... 171
6.2.5.3.5 France Digital Biomarkers Market (by Type) ......................................................... 171
6.2.5.3.6 France Digital Biomarkers Market (by Application)................................................ 172
6.2.5.4 Italy .................................................................................................................. 173
6.2.5.4.3 Italy Digital Biomarkers Market .............................................................................. 174
6.2.5.4.4 Italy Digital Biomarkers Market (by Type).............................................................. 174
6.2.5.4.5 Italy Digital Biomarkers Market (by Application) .................................................... 175
6.2.5.5 Spain................................................................................................................ 176
6.2.5.5.3 Spain Digital Biomarkers Market............................................................................ 176
6.2.5.5.4 Spain Digital Biomarkers Market (by Type) ........................................................... 177

6.2.5.5.5 Spain Digital Biomarkers Market (by Application).................................................. 178
6.2.5.6 Russia.............................................................................................................. 178
6.2.5.6.4 Russia Digital Biomarkers Market.......................................................................... 179
6.2.5.6.5 Russia Digital Biomarkers Market (by Type) ......................................................... 180
6.2.5.6.6 Russia Digital Biomarkers Market (by Application)................................................ 181
6.2.5.7 U.K................................................................................................................... 181
6.2.5.7.3 Increasing Sales of Smartwatches......................................................................... 182
6.2.5.7.4 Abandonment of Wearables .................................................................................. 182
6.2.5.7.5 Local Players in Digital Biomarkers ....................................................................... 182
6.2.5.7.6 U.K. Digital Biomarkers Market.............................................................................. 183
6.2.5.7.7 U.K. Digital Biomarkers Market (by Type) ............................................................. 183
6.2.5.7.8 U.K. Digital Biomarkers Market (by Application).................................................... 184
6.2.5.8 Rest-of-Europe ................................................................................................ 185
6.2.5.8.3 Increasing Sales of Smartwatches......................................................................... 185
6.2.5.8.4 Local Players in Digital Biomarkers ....................................................................... 186
6.2.5.8.5 Rest-of-Europe Digital Biomarkers Market ............................................................ 186
6.2.5.8.6 Rest-of-Europe Digital Biomarkers Market (by Type)............................................ 186
6.2.5.8.7 Rest-of-Europe Digital Biomarkers Market (by Application) .................................. 187
6.3 Asia-Pacific Digital Biomarkers Market .......................................................188
6.3.3 Market Dynamics.......................................................................................190
6.3.3.1 Impact Analysis................................................................................................ 190

6.3.4.1 Asia-Pacific Digital Biomarkers Market (by Application).................................. 191
6.3.4.2 Asia-Pacific Digital Biomarkers Market (by Type)............................................ 192
6.3.5 Asia-Pacific Digital Biomarkers Market (by Country).............................193
6.3.5.1 Singapore ........................................................................................................ 193
6.3.5.1.3 Degree of Adoption of Mobile Health..................................................................... 193
6.3.5.1.4 Singapore Digital Biomarkers Market .................................................................... 193
6.3.5.1.5 Singapore Digital Biomarkers Market (by Type).................................................... 194
6.3.5.1.6 Singapore Digital Biomarkers Market (by Application) .......................................... 195
6.3.5.2 Australia........................................................................................................... 195
6.3.5.2.4 Australia Digital Biomarkers Market....................................................................... 197
6.3.5.2.5 Australia Digital Biomarkers Market (by Type) ...................................................... 197
6.3.5.2.6 Australia Digital Biomarkers Market (by Application)............................................. 198
6.3.5.3 India................................................................................................................. 199
6.3.5.3.4 India Digital Biomarkers Market............................................................................. 200
6.3.5.3.5 India Digital Biomarkers Market (by Type)............................................................. 201
6.3.5.3.6 India Digital Biomarkers Market (by Application)................................................... 202
6.3.5.4 South Korea..................................................................................................... 202
6.3.5.4.4 South Korea Digital Biomarkers Market................................................................. 203

6.3.5.4.5 South Korea Digital Biomarkers Market (by Type) ................................................ 204
6.3.5.4.6 South Korea Digital Biomarkers Market (by Application)....................................... 205
6.3.5.5 Japan............................................................................................................... 205
6.3.5.5.4 Japan Digital Biomarkers Market........................................................................... 206
6.3.5.5.5 Japan Digital Biomarkers Market (by Type)........................................................... 207
6.3.5.5.6 Japan Digital Biomarkers Market (by Application)................................................. 208
6.3.5.6 China ............................................................................................................... 208
6.3.5.6.4 Local Players in Digital Biomarker Market ............................................................. 210
6.3.5.6.5 China Digital Biomarkers Market ........................................................................... 210
6.3.5.6.6 China Digital Biomarkers Market (by Type)........................................................... 211
6.3.5.6.7 China Digital Biomarkers Market (by Application) ................................................. 211
6.3.5.7 Rest-of-Asia-Pacific ......................................................................................... 212
6.3.5.7.4 Rest-of-Asia-Pacific Digital Biomarkers Market..................................................... 213
6.3.5.7.5 Rest-of-Asia-Pacific Digital Biomarkers Market (by Type)..................................... 214
6.3.5.7.6 Rest-of-Asia-Pacific Digital Biomarkers Market (by Application)........................... 214
6.4 Latin America Digital Biomarkers Market....................................................215
6.4.3 Market Dynamics.......................................................................................216
6.4.3.1 Impact Analysis................................................................................................ 217

6.4.4.1 Latin America Digital Biomarkers Market (by Application)............................... 218
6.4.4.2 Latin America Digital Biomarkers Market (by Type) ........................................ 219
6.4.5 Latin America Digital Biomarkers Market (by Country) .........................220
6.4.5.1 Brazil................................................................................................................ 220
6.4.5.1.3 Brazil Digital Biomarkers Market............................................................................ 221
6.4.5.1.4 Brazil Digital Biomarkers Market (by Type) ........................................................... 221
6.4.5.1.5 Brazil Digital Biomarkers Market (by Application).................................................. 222
6.4.5.2 Mexico ............................................................................................................. 223
6.4.5.2.3 Mexico Digital Biomarkers Market ......................................................................... 224
6.4.5.2.4 Mexico Digital Biomarkers Market (by Type)......................................................... 224
6.4.5.2.5 Mexico Digital Biomarkers Market (by Application) ............................................... 225
6.4.5.3 Rest-of-Latin America...................................................................................... 226
6.4.5.3.4 Rest-of-Latin America Digital Biomarkers Market.................................................. 227
6.4.5.3.5 Rest-of-Latin America Digital Biomarkers Market (by Type) ................................. 228
6.4.5.3.6 Rest-of-Latin America Digital Biomarkers Market (by Application)........................ 228
6.5 Rest-of-the-World ..........................................................................................229
6.5.3 Market Dynamics.......................................................................................230
6.5.3.1 Impact Analysis................................................................................................ 231
6.5.4.1 Rest-of-the-World Digital Biomarkers Market (by Application) ........................ 232
6.5.4.2 Rest-of-the-World Digital Biomarkers Market (by Type) .................................. 233

6.5.5 Rest-of-the-World Digital Biomarkers Market (by Country)...................234
6.5.5.1 Saudi Arabia .................................................................................................... 234
6.5.5.1.4 Saudi Arabia Digital Biomarkers Market................................................................ 235
6.5.5.1.5 Saudi Arabia Digital Biomarkers Market (by Type)................................................ 235
6.5.5.1.6 Saudi Arabia Digital Biomarkers Market (by Application) ...................................... 236
6.5.5.2 U.A.E ............................................................................................................... 237
6.5.5.2.4 U.A.E. Digital Biomarkers Market .......................................................................... 237
6.5.5.2.5 U.A.E. Digital Biomarkers Market (by Type).......................................................... 238
6.5.5.2.6 U.A.E. Digital Biomarkers Market (by Application) ................................................ 239
6.5.5.3 Israel................................................................................................................ 239
6.5.5.3.4 Israel Digital Biomarkers Market............................................................................ 240
6.5.5.3.5 Israel Digital Biomarkers Market (by Type)............................................................ 241
6.5.5.3.6 Israel Digital Biomarkers Market (by Application).................................................. 241
6.5.5.4 South Africa ..................................................................................................... 242
6.5.5.4.4 South Africa Digital Biomarkers Market ................................................................. 243
6.5.5.4.5 South Africa Digital Biomarkers Market (by Type)................................................. 244
6.5.5.4.6 South Africa Digital Biomarkers Market (by Application) ....................................... 244
6.5.5.5 Rest-of-Rest-of-the-World................................................................................ 245

6.5.5.5.4 Rest-of-Rest-of -the-World Digital Biomarkers Market .......................................... 246
6.5.5.5.5 Rest-of-Rest-of-the-World Digital Biomarkers Market (by Type)........................... 247
6.5.5.5.6 Rest-of-Rest-of-the-World Digital Biomarkers Market (by Application) ................. 247
7. Market- Company Profiles and Competitive Benchmarking .........249
7.1 Competitive Landscape ................................................................................249
7.1.1 Key Strategies and Developments...........................................................249
7.1.1.1 Partnerships, Alliances, and Business Expansions ......................................... 250
7.1.1.2 Funding Activities............................................................................................. 251
7.1.1.2.1 New Offerings ........................................................................................................ 251
7.1.1.2.2 Mergers and Acquisitions....................................................................................... 252
7.1.1.2.3 Regulatory and Legal Activities.............................................................................. 253
7.2 Company Profiles ..........................................................................................254
7.2.1 Established Companies............................................................................254
7.2.1.1 Alphabet Inc..................................................................................................... 254
7.2.1.1.1 Company Overview................................................................................................ 254
7.2.1.1.2 Role of Alphabet Inc. in the Global Digital Biomarkers Market.............................. 254
7.2.1.1.3 Product Portfolio and Offerings.............................................................................. 255
7.2.1.1.4 Financials............................................................................................................... 256
7.2.1.1.4.1 Recent Developments .................................................................................... 257
7.2.1.1.5 SWOT Analysis...................................................................................................... 259
7.2.1.2 AliveCor Inc. .................................................................................................... 260
7.2.1.2.2 Role of AliveCor, Inc. in the Global Digital Biomarkers Market ............................. 260
7.2.1.2.4 Recent Development ............................................................................................. 261
7.2.1.2.5 SWOT Analysis...................................................................................................... 262
7.2.1.3 Akili Interactive Labs, Inc................................................................................. 263

7.2.1.3.2 Role of Akili Interactive Labs in the Global Digital Biomarkers Market.................. 263
7.2.1.3.3.1.1 Recent Developments ...........................................................................................264
7.2.1.3.3.1.2 SWOT Analysis .....................................................................................................264
7.2.1.4 Cambridge Cognition Ltd................................................................................. 265
7.2.1.4.2 Role of Cambridge Cognition Ltd in the Global Digital Biomarkers Market........... 265
7.2.1.4.4 Financials............................................................................................................... 266
7.2.1.4.5 Recent Developments............................................................................................ 268
7.2.1.4.6 SWOT Analysis...................................................................................................... 269
7.2.1.5 Dassault Systèmes.......................................................................................... 270
7.2.1.5.2 Role of Dassault Systèmes in the Global Digital Biomarkers Market.................... 270
7.2.1.5.4 Financials............................................................................................................... 272
7.2.1.5.6 SWOT Analysis...................................................................................................... 274
7.2.1.6 IXICO plc ......................................................................................................... 276
7.2.1.6.2 Role of IXICO plc in the Global Digital Biomarkers Market ................................... 276
7.2.1.6.4 Financials............................................................................................................... 278
7.2.1.6.6 SWOT Analysis...................................................................................................... 280
7.2.1.7 Koninklijke Philips N.V..................................................................................... 281
7.2.1.7.2 Role of Koninklijke Philips N.V. in the Global Digital Biomarkers Market.............. 281

7.2.1.7.4 Financials............................................................................................................... 282
7.2.1.7.4.1 Koninklijke Philips N.V.: SWOT Analysis........................................................ 284
7.2.1.8 Shimmer .......................................................................................................... 286
7.2.1.8.2 Role of Shimmer in the Global Digital Biomarkers Market .................................... 286
7.2.1.8.3.1 Recent Developments .................................................................................... 287
7.2.1.8.4 SWOT Analysis...................................................................................................... 288
7.2.1.9 Quanterix Corporation ..................................................................................... 289
7.2.1.9.2 Role of Quanterix Corporation in the Global Digital Biomarkers Market ............... 289
7.2.1.9.4 Financials............................................................................................................... 290
7.2.1.9.6 SWOT Analysis...................................................................................................... 292
7.2.2 Start-Ups ....................................................................................................294
7.2.2.1 Altoida AG........................................................................................................ 294
7.2.2.1.2 Role of Altoida AG in the Global Digital Biomarkers Market.................................. 294
7.2.2.1.5 SWOT Analysis...................................................................................................... 295
7.2.2.2 Evidation Health, Inc........................................................................................ 296
7.2.2.2.2 Role of Evidation Health, Inc. in the Global Digital Biomarker Market................... 296
7.2.2.2.5 SWOT Analysis...................................................................................................... 297
7.2.2.3 Happify, Inc...................................................................................................... 298

7.2.2.3.2 Role of Happify, Inc. in the Global Digital Biomarker Market................................. 298
7.2.2.3.5 SWOT Analysis...................................................................................................... 299
7.2.2.4 Huma ............................................................................................................... 300
7.2.2.4.2 Role of Huma in the Global Digital Biomarker Market ........................................... 300
7.2.2.4.5 SWOT Analysis...................................................................................................... 301
7.2.2.5 Human API ...................................................................................................... 302
7.2.2.5.2 Role of Human API in the Global Digital Biomarkers Market. ............................... 302
7.2.2.5.5 SWOT Analysis...................................................................................................... 303
7.2.2.6 Mindstrong Health............................................................................................ 304
7.2.2.6.2 Role of Mindstrong Health in the Global Digital Biomarker Market ....................... 304
7.2.2.6.5 SWOT Analysis...................................................................................................... 305
7.2.2.7 Neurotrack Technologies, Inc.......................................................................... 306
7.2.2.7.2 Role of Neurotrack Technologies, Inc. in the Global Digital Biomarker
Market ................................................................................................................... 306
7.2.2.7.5 SWOT Analysis...................................................................................................... 307
7.2.2.8 Orikami ............................................................................................................ 308

7.2.2.8.2 Role of Orikami in the Global Digital Biomarker Market ........................................ 308
7.2.2.8.5 SWOT Analysis...................................................................................................... 309
7.2.2.9 Winterlight Labs Inc. ........................................................................................ 310
7.2.2.9.2 Role of Winterlight Labs, Inc. in the Global Digital Biomarkers Market ................. 310
7.2.2.9.5 SWOT Analysis...................................................................................................... 311

List of Figures
Figure 1: Evolution of Digital Health
Figure 2: Applications of Digital Biomarkers
Figure 3: Global Digital Biomarkers Market, Impact Analysis
Figure 4: Global Digital Biomarkers Market Potential, $Million, 2020, 2024, and 2028
Figure 5: Global Digital Biomarkers Market (by System Components), $Million, 2021,2024 and 2028
Figure 6: Global Digital Biomarkers Market (by End User), $Million, 2019-2028
Figure 7: Global Digital Biomarker Market, Key Developments and Strategies, January 2017-December
2021
Figure 8: Growth-Share Matrix of the Global Digital Biomarkers Market, 2021-2028
Figure 9: Global Digital Biomarkers Market Segmentation
Figure 10: Global Digital Biomarkers Market: Research Methodology
Figure 11: Primary Research
Figure 12: Secondary Research
Figure 13: Data Triangulation
Figure 14: Global Digital Biomarkers Market Research Process
Figure 15: Assumptions and Limitations
Figure 16: Global Digital Biomarkers Market, Realistic Growth Scenario, $Million, 2019-2028
Figure 17: Global Digital Biomarkers Market, Optimistic Growth Scenario, $Million, 2019-2028
Figure 18: Global Digital Biomarkers Market, Pessimistic Growth Scenario, $Million, 2019-2028
Figure 19: Digital Biomarkers Ecosystem
Figure 20: Workflow of Digital Health Tools
Figure 21: Global Digital Biomarkers Market, Short-Term Growth Potential, $Million, 2022-2025
Figure 22: Global Digital Biomarkers Market, Long-Term Growth Potential, $Million, 2026-2028
Figure 23: Global Digital Biomarkers Market, Product Benchmarking
Figure 24: Global Digital Biomarkers Market, Patent Publication Growth Trend, January 2019-December
2021
Figure 25: Global Digital Biomarkers Market, Patent Filing Trend (by Country/Cluster), January 2019-
December 2021
Figure 26: Applications of Wearables in COVID-19
Figure 27: Digital Biomarkers and COVID-19 Pandemic
Figure 28: Global Digital Biomarkers Market Pre-COVID-19 Scenario, $Million, 2020-2028

Figure 29: Global Digital Biomarkers Market Y-o-Y Growth Comparative Analysis (With COVID-19 Vs.
Without COVID-19)
Figure 30: Impact Trends and Scenarios During COVID-19 (by Region), 2020-2021
Figure 31: Global Digital Biomarkers Market, Impact Analysis
Figure 32: Process of Transmission of Data in Digital Biomarkers
Figure 33: Healthcare Interoperability Challenges
Figure 34: Global Digital Biomarkers Market (by Application)
Figure 35: Global Digital Biomarkers Market Incremental Opportunity (by Application), $Million, 2022-
2028
Figure 36: Global Digital Biomarkers Market, Growth-Share Matrix (by Application), 2021-2028
Figure 37: Global Digital Biomarkers Market (Gastrointestinal Diseases), $Million, 2019-2028
Figure 38: Global Digital Biomarkers Market (Sleep and Movement Disorders), $Million, 2019-2028
Figure 39: Global Digital Biomarkers Market (Cardiovascular), $Million, 2019-2028
Figure 40: Global Digital Biomarkers Market (Psychiatric Disorders (Mood and Behavior)), $Million, 2019-
2028
Figure 41: Global Digital Biomarkers Market (Chronic Pain), $Million, 2019-2028
Figure 42: Global Digital Biomarkers Market (Neurodegenerative Disorders), $Million, 2019-2028
Figure 43: Global Digital Biomarkers Market (Diabetes), $Million, 2019-2028
Figure 44: Global Digital Biomarkers Market (Respiratory Diseases), $Million, 2019-2028
Figure 45: Global Digital Biomarkers Market (Others), $Million, 2019-2028
Figure 46: Global Digital Biomarkers Market (by End User)
Figure 47: Global Digital Biomarkers Market Incremental Opportunity (by End User), $Million, 2022-2028
Figure 48: Global Digital Biomarkers Market, Growth-Share Matrix (by End User), 2021e-2028
Figure 49: Global Digital Biomarkers Market (Biopharmaceutical Companies), $Million, 2019-2028
Figure 50: Global Digital Biomarkers Market (Payers), $Million, 2019-2028
Figure 51: Global Digital Biomarkers Market (Providers), $Million, 2019-2028
Figure 52: Global Digital Biomarkers Market (by System Components)
Figure 53: Global Digital Biomarkers Market Incremental Opportunity (by Product Type), $Million, 2022-
2028
Figure 54: Market Share Analysis (by System Components), $Million, 2021
Figure 55: Global Digital Biomarkers Market, Growth-Share Matrix (by System Components), 2021-2028
Figure 56: Global Digital Biomarker Data Collection Tools Market, $Million, 2019-2028
Figure 57: Applications of Healthcare Wearables
Figure 58: Number of Clinical Trials Using Connected Wearable Devices (by Year) (Cumulative)

Figure 59: Global Digital Biomarkers Market (Wearable Devices), $Million, 2019-2028
Figure 60: Global Digital Biomarkers Market (Implantables), $Million, 2019-2028
Figure 61: Benefits of mHealth
Figure 62: Global Digital Biomarkers Market (Mobile Applications), $Million, 2019-2028
Figure 63: Process of Data Integration in Remote Patient Monitoring (RPM)
Figure 64: Global Digital Biomarkers Market (Data Integration Software), $Million, 2019-2028
Figure 65: Global Digital Biomarkers Market (by Type)
Figure 66: Global Digital Biomarkers Market Incremental Opportunity (by Type), $Million, 2022-2028
Figure 67: Market Share Analysis (by System Components), $Million, 2021
Figure 68: Global Digital Biomarkers Market, Growth-Share Matrix (by Type), 2021-2028
Figure 69: Global Digital Biomarkers Market (Clinical Trials), $Million, 2019-2028
Figure 70: Global Digital Biomarkers Market (Clinical Settings), $Million, 2019-2028
Figure 71: North America Digital Biomarkers Market Incremental Growth Opportunity (by Country),
$Million, 2022-2028
Figure 72: North America Digital Biomarkers Market, $Million, 2019-2028
Figure 73: North America Digital Biomarkers Market (by Application), $Million, 2019-2028
Figure 74: North America Digital Biomarkers Market (By Type), $Million, 2019-2028
Figure 75: U.S. Digital Biomarkers Market, $Million, 2019-2028
Figure 76: U.S. Digital Biomarkers Market (by Product Type), $Million, 2019-2028
Figure 77: U.S. Digital Biomarkers Market (by Application), $Million, 2019-2028
Figure 78: Canada Digital Biomarkers Market, $Million, 2019-2028
Figure 79: Canada Digital Biomarkers Market (by Type), $Million, 2019-2028
Figure 80: Canada Digital Biomarkers Market (by Application), $Million, 2019-2028
Figure 81: Europe Digital Biomarkers Market Incremental Growth Opportunity (by Country), $Million,
2022-2028
Figure 82: Europe Digital Biomarkers Market, $Million, 2019-2028
Figure 83: Europe Digital Biomarkers Market (by Application), $Million, 2019-2028
Figure 84: Europe Digital Biomarkers Market (by Type), $Million, 2019-2028
Figure 85: Netherlands Digital Biomarkers Market, $Million, 2019-2028
Figure 86: Netherlands Digital Biomarkers Market (by Type), $Million, 2019-2028
Figure 87: Netherlands Digital Biomarkers Market (by Application), $Million, 2019-2028
Figure 88: Germany Digital Biomarkers Market, $Million, 2019-2028
Figure 89: Germany Digital Biomarkers Market (by Type), $Million, 2019-2028

Figure 90: Germany Digital Biomarkers Market (by Application), $Million, 2019-2028
Figure 91: France Digital Biomarkers Market, $Million, 2019-2028
Figure 92: France Digital Biomarkers Market (by Type), $Million, 2019-2028
Figure 93: France Digital Biomarkers Market (by Application), $Million, 2019-2028
Figure 94: Italy Digital Biomarkers Market, $Million, 2019-2028
Figure 95: Italy Digital Biomarkers Market (by Type), $Million, 2019-2028
Figure 96: Italy Digital Biomarkers Market (by Application), $Million, 2019-2028
Figure 97: Spain Digital Biomarkers Market, $Million, 2019-2028
Figure 98: Spain Digital Biomarkers Market (by Type), $Million, 2019-2028
Figure 99: Spain Digital Biomarkers Market (by Application), $Million, 2019-2028
Figure 100: Russia Digital Biomarkers Market, $Million, 2019-2028
Figure 101: Russia Digital Biomarkers Market (by Type), $Million, 2019-2028
Figure 102: Russia Digital Biomarkers Market (by Application), $Million, 2019-2028
Figure 103: U.K. Digital Biomarkers Market, $Million, 2019-2028
Figure 104: U.K. Digital Biomarkers Market (by Type), $Million, 2019-2028
Figure 105: U.K. Digital Biomarkers Market (by Application), $Million, 2019-2028
Figure 106: Rest-of-Europe Digital Biomarkers Market, $Million, 2019-2028
Figure 107: Rest-of-Europe Digital Biomarkers Market (by Type), $Million, 2019-2028
Figure 108: Rest-of-Europe Digital Biomarkers Market (by Application), $Million, 2019-2028
Figure 109: Asia-Pacific Digital Biomarkers Market Incremental Growth Opportunity (by Country), $Million,
2022-2028
Figure 110: Asia-Pacific Digital Biomarkers Market, $Million, 2019-2028
Figure 111: Asia-Pacific Digital Biomarkers Market (by Application), $Million, 2019-2028
Figure 112: Asia-Pacific Digital Biomarkers Market (by Type), $Million, 2019-2028
Figure 113: Singapore Digital Biomarkers Market, $Million, 2019-2028
Figure 114: Singapore Digital Biomarkers Market (by Type), $Million, 2019-2028
Figure 115: Singapore Digital Biomarkers Market (by Application), $Million, 2019-2028
Figure 116: Australia Digital Biomarkers Market, $Million, 2019-2028
Figure 117: Australia Digital Biomarkers Market (by Type), $Million, 2019-2028
Figure 118: Australia Digital Biomarkers Market (by Application), $Million, 2019-2028
Figure 119: India Digital Biomarkers Market, $Million, 2019-2028
Figure 120: India Digital Biomarkers Market (by Type), $Million, 2019-2028
Figure 121: India Digital Biomarkers Market (by Application), $Million, 2019-2028

Figure 122: South Korea Digital Biomarkers Market, $Million, 2019-2028
Figure 123: South Korea Digital Biomarkers Market (by Type), $Million, 2019-2028
Figure 124: South Korea Digital Biomarkers Market (by Application), $Million, 2019-2028
Figure 125: Japan Digital Biomarkers market, $Million, 2019-2028
Figure 126: Japan Digital Biomarkers Market (by Type), $Million, 2019-2028
Figure 127: Japan Digital Biomarkers Market (by Application), $Million, 2019-2028
Figure 128: China Digital Biomarkers Market, $Million, 2019-2028
Figure 129: China Digital Biomarkers Market (by Type), $Million, 2019-2028
Figure 130: China Digital Biomarkers Market (by Application), $Million, 2019-2028
Figure 131: Rest-of-Asia-Pacific Digital Biomarkers Market, $Million, 2019-2028
Figure 132: Rest-of-Asia-Pacific Digital Biomarkers Market (by Type), $Million, 2019-2028
Figure 133: Rest-of-Asia-Pacific Digital Biomarkers Market (by Application), $Million, 2019-2028
Figure 134: Latin America Digital Biomarkers Market Incremental Growth Opportunity (by Country),
$Million, 2022-2028
Figure 135: Latin America Digital Biomarkers Market, $Million, 2019-2028
Figure 136: Latin America Digital Biomarkers Market (by Application), $Million, 2019-2028
Figure 137: Latin America Digital Biomarkers Market (by Type), $Million, 2019-2028
Figure 138: Brazil Digital Biomarkers Market, $Million, 2019-2028
Figure 139: Brazil Digital Biomarkers Market (by Type), $Million, 2019-2028
Figure 140: Brazil Digital Biomarkers Market (by Application), $Million, 2019-2028
Figure 141: Mexico Digital Biomarkers Market, $Million, 2019-2028
Figure 142: Mexico Digital Biomarkers Market (by Type), $Million, 2019-2028
Figure 143: Mexico Digital Biomarkers Market (by Application), $Million, 2019-2028
Figure 144: Rest-of-Latin America Digital Biomarkers Market, $Million, 2019-2028
Figure 145: Rest-of-Latin America Digital Biomarkers Market (by Type), $Million, 2019-2028
Figure 146: Rest-of-Latin America Digital Biomarkers Market (by Application), $Million, 2019-2028
Figure 147: Rest-of-the-World Digital Biomarkers Market Regulations
Figure 148: Rest-of-the-World Digital Biomarkers Market Incremental Growth Opportunity (by Country),
$Million, 2022-2028
Figure 149: Rest-of-the-World Digital Biomarkers market, $Million, 2019-2028
Figure 150: Rest-of-the-World Digital Biomarkers Market (by Application), $Million, 2019-2028
Figure 151: Rest-of-the-World Digital Biomarkers Market (by Type), $Million, 2019-2028
Figure 152: Saudi Arabia Digital Biomarkers Market, $Million, 2019-2028

Figure 153: Saudi Arabia Digital Biomarkers Market (by Type), $Million, 2019-2028
Figure 154: Saudi Arabia Digital Biomarkers Market (by Application), $Million, 2019-2028
Figure 155: U.A.E. Digital Biomarkers Market, $Million, 2019-2028
Figure 156: U.A.E. Digital Biomarkers Market (by Type), $Million, 2019-2028
Figure 157: U.A.E. Digital Biomarkers Market (by Application), $Million, 2019-2028
Figure 158: Israel Digital Biomarkers Market, $Million, 2019-2028
Figure 159: Israel Digital Biomarkers Market (by Type), $Million, 2019-2028
Figure 160: Israel Digital Biomarkers Market (by Application), $Million, 2019-2028
Figure 161: South Africa Digital Biomarkers Market, $Million, 2019-2028
Figure 162: South Africa Digital Biomarkers Market (by Type), $Million, 2019-2028
Figure 163: South Africa Digital Biomarkers Market (by Application), $Million, 2019-2028
Figure 164: Rest-of-Rest-of-the-World Digital Biomarkers Market, $Million, 2019-2028
Figure 165: Rest-of-Rest-of-the-World Digital Biomarkers Market (by Type), $Million, 2019-2028
Figure 166: Rest-of-Rest-of-the-World Digital Biomarkers Market (by Application), $Million, 2019-2028
Figure 167: Global Digital Biomarkers Market, Key Developments, January 2017-February 2022
Figure 168: Partnerships, Alliances, and Business Expansions Share (by Company), January 2017-
February 2022
Figure 169: Funding Activities (by Company), January 2017-February 2022
Figure 170: New Product Offerings and Upgradations Share (by Company), January 2017-February 2022
Figure 171: Mergers and Acquisitions (by Company), January 2017-February 2022
Figure 172: Regulatory and Legal Activities Share (by Company), January 2017-February 2022
Figure 173: Alphabet Inc.: Overall Product Portfolio
Figure 174: Alphabet Inc.: Overall Financials, $Million, 2019-2021
Figure 175: Alphabet Inc.: R&D Expenditure, $Million, 2019-2021
Figure 176: Alphabet Inc.: Revenue (by Region), $Million, 2019-2021
Figure 177: AliveCor, Inc: Overall Product Portfolio
Figure 178: Akili Interactive Labs: Overall Product Portfolio
Figure 179: Cambridge Cognition Ltd.: Overall Product Portfolio
Figure 180: Cambridge Cognition Ltd: Overall Financials, $Million, 2018-2020
Figure 181: Cambridge Cognition Ltd: Net Revenue (by Segment), $Million, 2018-2020
Figure 182: Cambridge Cognition Ltd: Net Revenue (by Region), $Million, 2018-2020
Figure 183: Cambridge Cognition Ltd: R&D Expenditure, $Million, 2018-2020
Figure 184: Dassault Systèmes: Overall Product Portfolio

Figure 185: Dassault Systèmes: Overall Financials, $Million, 2018-2020
Figure 186: Dassault Systèmes: Net Revenue (by Segment), $Million, 2018-2020
Figure 187: Dassault Systèmes: Net Revenue (by Region), $Million, 2018-2020
Figure 188: Dassault Systèmes: R&D Expenditure, $Million, 2019-2021
Figure 189: IXICO plc: Overall Product Portfolio
Figure 190: IXICO plc: Overall Financials, $Million, 2019-2021
Figure 191: IXICO plc: R&D Expenditure, $Million, 2019-2021
Figure 192: IXICO plc: Revenue (by Region), $Million, 2020-2021
Figure 193: Koninklijke Philips N.V.: Overall Product Portfolio
Figure 194: Koninklijke Philips N.V.: Overall Financials, $Million, 2019-2021
Figure 195: Koninklijke Philips N.V.: Net Revenue (by Segment), $Million, 2019-2021
Figure 196: Koninklijke Philips N.V.: Net Revenue (by Region), $Million, 2019-2021
Figure 197: Koninklijke Philips N.V.: R&D Expenditure, $Million, 2019-2021
Figure 198: Shimmer: Overall Product Portfolio
Figure 199: Quanterix Corporation: Overall Product Portfolio
Figure 200: Quanterix Corporation: Overall Financials, $Million, 2018-2020
Figure 201: Quanterix Corporation: Net Revenue (by Segment), $Million, 2018-2020
Figure 202: Quanterix Corporation: Net Revenue (by Region), $Million, 2018-2020
Figure 203: Quanterix Corporation: R&D Expenditure, $Million, 2018-2020
Figure 204: Altoida, AG: Overall Product Portfolio
Figure 205: Evidation Health, Inc.: Overall Product Portfolio
Figure 206: Happify, Inc.: Overall Product Portfolio
Figure 207: Huma: Overall Product Portfolio
Figure 208: Human API: Overall Product Portfolio
Figure 209: Mindstrong Health: Overall Product Portfolio
Figure 210: Neurotrack Technologies, Inc.: Overall Product Portfolio
Figure 211: Orikami: Overall Product Portfolio
Figure 212: Winterlight Labs, Inc.: Overall Product Portfolio

List of Tables
Table 1: Challenges in the Global Digital Biomarkers Market
Table 2: Global Digital Biomarkers: Key Trends
Table 3: Awaited Technological Developments in the Global Digital Biomarkers Market
Table 4: Summary Of Research Studies Performed on Screening, Tracking, and Prevention of COVID-
19
Table 5: Features of Major Wearable Devices
Table 6: Global Digital Biomarkers Market, Major FDA Clearances, 2022
Table 7: Commercially Available Mobile Applications Used for Monitoring and Managing Inflammatory
Bowel’s Disease
Table 8: Key Developments in the Gastrointestinal Diseases Space Using Digital Health
Table 9: Key Developments in Sleep and Movement Disorders Using Digital Health
Table 10: Key Developments in Cardiovascular Diseases Space Using Digital Health
Table 11: Key Developments in the Mood-Related Disorders Space Using Digital Health
Table 12: Key Developments in Chronic Pain Space Using Digital Health
Table 13: Key Developments in Neurodegenerative Disorders Space Using Digital Health
Table 14: Key Developments in Diabetes Space Using Digital Health
Table 15: Leading Respiratory Conditions and its Incidence (in Million)
Table 16: Key Developments in Respiratory Diseases Space Using Digital Health
Table 17: Commercial Products Available, Implantable Devices
Table 18: North America Digital Biomarkers Market: Regulatory Framework
Table 19: North America Digital Biomarkers Market, Impact Analysis
Table 20: Europe Digital Biomarkers Market Regulatory Framework
Table 21: Challenges in MDR Implementation
Table 22: Europe Digital Biomarkers Market, Impact Analysis
Table 23: Asia-Pacific Digital Biomarkers Market Regulatory Framework
Table 24: Asia-Pacific Digital Biomarkers Market, Impact Analysis
Table 25: Latin America Digital Biomarkers Market Regulations
Table 26: Latin America Digital Biomarkers Market, Impact Analysis
Table 27: Rest-of-the-World Digital Biomarkers Market, Impact Analysis

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