2. GLOBAL BIO BANK:c
Organized collection and storage of human biological samples and Associated data of
great significance for research And personalized medicine.
Bio bank consists of 3 types of Information =
1. Attached or connected information
2. The consent and patinets individual data safety and protection
3. Biospecimens
BIOSPECIMENS : It includes Amnoitic fluid,Bone marrow stem cells and tissues,fresh
frozen plasma ,RNA ,DNA,protein ,Cerebrospinal fluid,blood ,urine,Synovial fluid,blood
etc.
3. BIOBANKING MAIN COMPONENTS
1.Biologic material handling
- Biospecimen Collection
- Biospecimen Processing
- Biospecimen Storage
-Biospecimen Distribution
2.Database management system
‐ Informed consent
‐ Medical history and personal information
‐ life style data
‐ confidentiality
‐ Security
4. • BIOBANK HISTORY
• The history of Biobank is not long.
• The collection and Storage of human
tissue has been part of medical research
For nearly a century.
• The term “BioBank”first appeared
in the late 1990s.
• After 10 years broad term is evolved
5. BIOREPOSITARY:
• A biological repository that collects ,process,store and provides
Biospecimens to future scientific research.
• Biorepositary can contain specimens from Animals,human other living
organisms .
• PROCESS OF BIOBANKING:
7. • STORAGE OF SAMPLES :
• DNA,Serum,Plasma and Blood stored at ‐80degreeC.
• Tissue and cell lines are preserved in liquid nitrogen
freezers at ‐196degreeC.
BEST PRACTISES OF BIOBANKS:
Goal of biobank is to collect,store and disseminate specimens and related data.
Publications discussing best practises:
1. International Society Of Biological and Environmental Repositories
2. National Cancer Institute.
BIOBANK POPULATION GROUP:
1.Whole Population
2.Subset of Population
8. • BBMRI ‐Biobanking &Biomolecular Resources Research Infrastructure
Funded by ERIC (European Research
Infrstructure Consortium) .
Largest research Infrastructure project in Europe
It will form interface between specimens and data
and top level biological and medical research.
9. Centralized Vs Federated
BioBanking:
BioBank In India:
‐Brain Biobank,NIMHANS
Bangalore .
‐Tata Memorial Hospital
Tissue Bank.
‐Narayana Hrudayala Tissue
Bank &Stem cell research
Centre.
10. BIOBANK
BIOBANK: ETHICAL ISSUES
• For tissue banking freely given informed patient
Consent is mandatory.
Patient consent forms needs to be upgraded from
time to time following IRB regulations.
Confidentiality ‐very important aspect
Safety is crucial: material safety data sheet(MSDS)to
be distributed among staff for entire chemical
Compounds kept at the biobank
