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Glaucoma Management:
Evolving Paradigms
DR. HABIBA SULTANA
LONG TERM FELLOW GLAUCOMA
GLAUCOMA SPECIALIST
JUNIOR CONSULTANT, DEEP EYE CARE FOUNDATION,
RANGPUR
We will discuss
 Aim of glaucoma management.
 When and how to treat.
 Various treatment modalities.
Open angle glaucoma
√ Open angle.
√ Glaucomatous
optic nerve damage.
± Elevated IOP.
± Visual field
damage.
Closed angle glaucoma
√ Closed angle.
± Elevated IOP.
± Glaucomatous optic nerve
damage.
± Visual field damage.
Glaucoma assessment checklist
 Visual acuity.
 Refractive error.
 Pupils.
 Lid/sclera/conjunctiva.
 Cornea.
 Corneal thickness.
 Intraocular pressure.
Contd..
 Anterior segment.
 Angle structures.
 Iris.
 Lens.
Contd..
 Optic nerve.
 Fundus.
Contd..
 Visual field.
How to treat
Indicators of unstable open angle
glaucoma:
 Elevated intraocular pressure.
 Progressive optic nerve changes.
 Progressive visual field changes.
How to approach
Angle closure
Apposition of peripheral iris against the trabecular
meshwork resulting in obstruction of aqueous
outflow.
By mechanism in the anterior segment
 Pupillary block
glaucoma
 Plateau iris
configuration and
syndrome.
 Phacomorphic
glaucoma.
By time course and presence of
symptoms
 Acute angle closure glaucoma.
 Subacute angle closure glaucoma.
 Chronic angle closure glaucoma.
According to clinical examination
1.Primary angle closure suspect :
Greater than 270 ITC
+
Absence of PAS
+
Normal IOP, disc & visual field
According to clinical examination
2.Primary angle closure :
Greater than 270 ITC With
elevated IOP & or PAS
+
Normal disc & visual field
Peripheral anterior
synechiae
According to clinical examination(cont.)
3.Primary angle closure glaucoma:
Greater than 270 ITC
+
Elevated IOP
+
Optic nerve & visual
field damage
Management plan for patients in whom
iridotomy is indicated
 Preferred surgical treatment for
acute angle closure crisis.
 In a potentially occludable angle.
 Progressive narrowing of the
angle.
 Medication required that may
provoke pupillary block.
Management plan for patients in whom
iridotomy is indicated(contd)
 Symptoms suggesting prior angle closure.
 Fellow eye.
 Patients occupation makes it difficult to access
immediate care.
Initiating closed angle care
(International recommendations)
Diagnosis Clinical Findings
Essential
Treatment
Surgical Options
Acute or
Chronic Closed
Angle (Pupil
Block)
Iris-trabecular
contact
Iris bowing
Laser Iridotomy
Or
Surgical Iridectomy
(Laser to fellow Eye)
Lens
Extraction/IOL
± Trabeculectomy
+ Mitomycin C
Closed Angle
(plateau iris)
Iris-trabecular
contact
Flat iris
Laser Iridotomy
Or
Surgical Iridectomy
(Laser to fellow Eye)
&
Laser Iridoplasty
Lens
Extraction/IOL
± Trabeculectomy
+ Mitomycin C
Artificial intelligence in
glaucoma diagnosis
 Also known as machine intelligence,
refers to capability of a machine to
imitate human intelligence.
 Through the use of automated
computer vision image interpretation
offer a novel method of diagnostic
imaging.
 Have potential to incorporate structural
and functional changes over time.
 Potential to provide more accurate and
timely identification of progression.
Surgical intervention
Trabeculectomy
 Gold standard.
 IOP reduction <21mmHg in 86-96%.
 Aim is to create an alternative drainage pathway for
aqueous humor to exit the eye.
Minimally invasive glaucoma
surgery
 Provide safer and more efficient
IOP lowering.
 Inserted through an ab interno
approach.
 Target 3 anatomical space
,schlemm cana, suprachoroidal
and subconjuntival space.
Glaucoma drainage devices
 Preferred surgical option for refractory
glaucoma.
 In cases where trabeculectomy failure
rate is higher (Neovascular glaucoma
,uveitic and some congenital glaucoma).
Cyclodiode laser
 Most widely used method of ciliary
ablation with success rate 40-80%.
 Reduced aqueous production by
destruction of ciliary epithelium and
reduced vascular perfusion.
 Indicated in painful blind eye ,NVG
and refractory glaucoma with poor
or no visual potential.
Referral
 If diagnosis and management is in question.
 Condition is refractory to treatment.
 Patients with significant visual impairment or
blindness.
Take home message
 Glaucoma should be ruled out as part of every regular eye
examination.
 Differentiating open angle or angle closure by gonioscopy is
very much essential.
 Refferral should be done if diagnosis and management is in
question.
Reference
 Becker-Shaffer's, Diagnosis and therapy of Glaucoma 8th
edition
 Textbook of glaucoma– M.Bruce Shields 5th
edition.
 ICO glaucoma guideline.
Preffered practice pattern of angle closure glaucoma
 www.gonioscopy.org a website dedicated to gonioscopy -
video atlas
Thank You All

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Glaucoma management paradigms

  • 1. Glaucoma Management: Evolving Paradigms DR. HABIBA SULTANA LONG TERM FELLOW GLAUCOMA GLAUCOMA SPECIALIST JUNIOR CONSULTANT, DEEP EYE CARE FOUNDATION, RANGPUR
  • 2. We will discuss  Aim of glaucoma management.  When and how to treat.  Various treatment modalities.
  • 3. Open angle glaucoma √ Open angle. √ Glaucomatous optic nerve damage. ± Elevated IOP. ± Visual field damage.
  • 4. Closed angle glaucoma √ Closed angle. ± Elevated IOP. ± Glaucomatous optic nerve damage. ± Visual field damage.
  • 5. Glaucoma assessment checklist  Visual acuity.  Refractive error.  Pupils.  Lid/sclera/conjunctiva.  Cornea.  Corneal thickness.  Intraocular pressure.
  • 6. Contd..  Anterior segment.  Angle structures.  Iris.  Lens.
  • 10. Indicators of unstable open angle glaucoma:  Elevated intraocular pressure.  Progressive optic nerve changes.  Progressive visual field changes.
  • 12. Angle closure Apposition of peripheral iris against the trabecular meshwork resulting in obstruction of aqueous outflow.
  • 13. By mechanism in the anterior segment  Pupillary block glaucoma  Plateau iris configuration and syndrome.  Phacomorphic glaucoma.
  • 14. By time course and presence of symptoms  Acute angle closure glaucoma.  Subacute angle closure glaucoma.  Chronic angle closure glaucoma.
  • 15. According to clinical examination 1.Primary angle closure suspect : Greater than 270 ITC + Absence of PAS + Normal IOP, disc & visual field
  • 16. According to clinical examination 2.Primary angle closure : Greater than 270 ITC With elevated IOP & or PAS + Normal disc & visual field Peripheral anterior synechiae
  • 17. According to clinical examination(cont.) 3.Primary angle closure glaucoma: Greater than 270 ITC + Elevated IOP + Optic nerve & visual field damage
  • 18. Management plan for patients in whom iridotomy is indicated  Preferred surgical treatment for acute angle closure crisis.  In a potentially occludable angle.  Progressive narrowing of the angle.  Medication required that may provoke pupillary block.
  • 19. Management plan for patients in whom iridotomy is indicated(contd)  Symptoms suggesting prior angle closure.  Fellow eye.  Patients occupation makes it difficult to access immediate care.
  • 20. Initiating closed angle care (International recommendations) Diagnosis Clinical Findings Essential Treatment Surgical Options Acute or Chronic Closed Angle (Pupil Block) Iris-trabecular contact Iris bowing Laser Iridotomy Or Surgical Iridectomy (Laser to fellow Eye) Lens Extraction/IOL ± Trabeculectomy + Mitomycin C Closed Angle (plateau iris) Iris-trabecular contact Flat iris Laser Iridotomy Or Surgical Iridectomy (Laser to fellow Eye) & Laser Iridoplasty Lens Extraction/IOL ± Trabeculectomy + Mitomycin C
  • 21. Artificial intelligence in glaucoma diagnosis  Also known as machine intelligence, refers to capability of a machine to imitate human intelligence.  Through the use of automated computer vision image interpretation offer a novel method of diagnostic imaging.  Have potential to incorporate structural and functional changes over time.  Potential to provide more accurate and timely identification of progression.
  • 22.
  • 24. Trabeculectomy  Gold standard.  IOP reduction <21mmHg in 86-96%.  Aim is to create an alternative drainage pathway for aqueous humor to exit the eye.
  • 25.
  • 26. Minimally invasive glaucoma surgery  Provide safer and more efficient IOP lowering.  Inserted through an ab interno approach.  Target 3 anatomical space ,schlemm cana, suprachoroidal and subconjuntival space.
  • 27. Glaucoma drainage devices  Preferred surgical option for refractory glaucoma.  In cases where trabeculectomy failure rate is higher (Neovascular glaucoma ,uveitic and some congenital glaucoma).
  • 28.
  • 29. Cyclodiode laser  Most widely used method of ciliary ablation with success rate 40-80%.  Reduced aqueous production by destruction of ciliary epithelium and reduced vascular perfusion.  Indicated in painful blind eye ,NVG and refractory glaucoma with poor or no visual potential.
  • 30.
  • 31. Referral  If diagnosis and management is in question.  Condition is refractory to treatment.  Patients with significant visual impairment or blindness.
  • 32. Take home message  Glaucoma should be ruled out as part of every regular eye examination.  Differentiating open angle or angle closure by gonioscopy is very much essential.  Refferral should be done if diagnosis and management is in question.
  • 33. Reference  Becker-Shaffer's, Diagnosis and therapy of Glaucoma 8th edition  Textbook of glaucoma– M.Bruce Shields 5th edition.  ICO glaucoma guideline. Preffered practice pattern of angle closure glaucoma  www.gonioscopy.org a website dedicated to gonioscopy - video atlas