This document discusses using predictive analytics to detect, predict, and change behavior related to fraud, waste and abuse (F/W/A) in healthcare. It defines F/W/A and provides statistics on the large financial impact of F/W/A. A case study shows that a predictive modeling approach identified over $8 million in savings opportunities from a large Medicare program. The document recommends that healthcare organizations re-examine their current F/W/A practices, question if they are sufficiently reducing costs, and work proactively using predictive analytics to prevent losses from F/W/A.