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FIRST TRIMESTER OBS SCAN
Dr. Kazim
Resident Radiology
2
General consideration
 How pregnancy is detected
 Urine pregnancy test
 Blood test(beta hCG)
 Role of ultrasound
 Confirm intrauterine pregnancy
 Follow up the growth of pregnancy
 Evaluate complications
 Diagnose ectopic pregnancy and other pathologies
General considerations
 Transabdominal and transvaginal US have complementary role ; TVS
can show structures in more detail
 First sonographic finding in pregnancy is visualization of the GS
 A normal GS is rounded, with a thick echogenic rim around(double
decidual sac sign)
5
6
7
8
9
10
11
12
13
14
15
16
Definitive diagnostic criteria for IUP failure
Size based criteria;
1)CRL>7mm without cardiac activity
2)MSD>25mm without visible embryo
Time based criteria;
3) Absence of embryo with heart beat > 14 days after a scan that showed
GS without yolk sac
4) Absence of embryo with heart beat > 11 days after a scan that showed
GS with a yolk sac
18
Problems of early pregnancy
 Miscarriage
 Ectopic pregnancy
 Gestational trophoblastic disease
 Ovarian problems
 Uterine fibroids
 Pregnancy with IUCD
Miscarriage
 Approximately 20% of women attending early pregnancy units suffer a
miscarriage
 Most women will present with history of vaginal bleeding and or
abdominal pain
Ultrasound findings
Miscarriage is classified into
 Threatened ; hx of vaginal bleeding + normal embryo seen by usg
 Missed ; absence of cardiac activity in fetal pole
 Blighted ovum ; absence of embryonic pole in a GS that measures 8
weeks
 Incomplete ; V.bleeding ,cramps + RPOC
 Complete ; V.bleeding ,cramps + thin endometrium “no RPOC”
22
23
Ectopic pregnancy
Is a life threatening condition
Presents with abdominal pain + amenorrhea +/- vaginal bleeding
Most commonly(95%) occurs in ampullary or isthmic portions of the
fallopian tube
Usg shows adnexal mass that contains a yolk sac or viable embryo
25
Gestational trophoblastic disease
 GTD is a spectrum of both benign and malignant gestational tumors,
including hydatidiform mole (complete 46XX or XY—80 % or partial
69XXX or XXY )and gestational trophoblastic neoplasia.
 Uterine bleeding is the most common presentation
 Diagnosed by markedly elevated beta hCG level expected for the stage
of gestation and by the characteristic sonographic appearance from 8
weeks
Gestational trophoblastic disease
Complete mole; sonographic features
 Enlarged uterus
 May be seen as intrauterine mass with cystic spaces without any
associated fetal part, giving the appearance of snow storm or bunch of
grapes
Partial mole; well formed but growth retarded fetus
 Enlarged placenta, cystic spaces with in placenta
complete mole partial mole
29
Nuchal transluency
 Nuchal translucency is the normal fluid filled subcutaneous space
identified at the back of the fetal neck during the late 1st and early 2nd
trimester(11 to 14 weeks)
 Thickening of the nuchal translucency can be associated with
 Aneuploidy (down syndrome or turner syndrome)
 Congenital heart disease
 Noonan syndrome
 Miscarriage
31
Heterotrophic pregnancy
Heterotrophic pregnancy is a rare condition when there is an
intrauterine and extrauterine pregnancy(i.e. ectopic pregnancy)
occurring simultaneously
32
33
34
35

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First trimester ultrasound.pptx

  • 1.
  • 2. FIRST TRIMESTER OBS SCAN Dr. Kazim Resident Radiology 2
  • 3. General consideration  How pregnancy is detected  Urine pregnancy test  Blood test(beta hCG)  Role of ultrasound  Confirm intrauterine pregnancy  Follow up the growth of pregnancy  Evaluate complications  Diagnose ectopic pregnancy and other pathologies
  • 4. General considerations  Transabdominal and transvaginal US have complementary role ; TVS can show structures in more detail  First sonographic finding in pregnancy is visualization of the GS  A normal GS is rounded, with a thick echogenic rim around(double decidual sac sign)
  • 5. 5
  • 6. 6
  • 7. 7
  • 8. 8
  • 9. 9
  • 10. 10
  • 11. 11
  • 12. 12
  • 13. 13
  • 14. 14
  • 15. 15
  • 16. 16
  • 17. Definitive diagnostic criteria for IUP failure Size based criteria; 1)CRL>7mm without cardiac activity 2)MSD>25mm without visible embryo Time based criteria; 3) Absence of embryo with heart beat > 14 days after a scan that showed GS without yolk sac 4) Absence of embryo with heart beat > 11 days after a scan that showed GS with a yolk sac
  • 18. 18
  • 19. Problems of early pregnancy  Miscarriage  Ectopic pregnancy  Gestational trophoblastic disease  Ovarian problems  Uterine fibroids  Pregnancy with IUCD
  • 20. Miscarriage  Approximately 20% of women attending early pregnancy units suffer a miscarriage  Most women will present with history of vaginal bleeding and or abdominal pain
  • 21. Ultrasound findings Miscarriage is classified into  Threatened ; hx of vaginal bleeding + normal embryo seen by usg  Missed ; absence of cardiac activity in fetal pole  Blighted ovum ; absence of embryonic pole in a GS that measures 8 weeks  Incomplete ; V.bleeding ,cramps + RPOC  Complete ; V.bleeding ,cramps + thin endometrium “no RPOC”
  • 22. 22
  • 23. 23
  • 24. Ectopic pregnancy Is a life threatening condition Presents with abdominal pain + amenorrhea +/- vaginal bleeding Most commonly(95%) occurs in ampullary or isthmic portions of the fallopian tube Usg shows adnexal mass that contains a yolk sac or viable embryo
  • 25. 25
  • 26. Gestational trophoblastic disease  GTD is a spectrum of both benign and malignant gestational tumors, including hydatidiform mole (complete 46XX or XY—80 % or partial 69XXX or XXY )and gestational trophoblastic neoplasia.  Uterine bleeding is the most common presentation  Diagnosed by markedly elevated beta hCG level expected for the stage of gestation and by the characteristic sonographic appearance from 8 weeks
  • 27. Gestational trophoblastic disease Complete mole; sonographic features  Enlarged uterus  May be seen as intrauterine mass with cystic spaces without any associated fetal part, giving the appearance of snow storm or bunch of grapes Partial mole; well formed but growth retarded fetus  Enlarged placenta, cystic spaces with in placenta
  • 29. Nuchal transluency  Nuchal translucency is the normal fluid filled subcutaneous space identified at the back of the fetal neck during the late 1st and early 2nd trimester(11 to 14 weeks)  Thickening of the nuchal translucency can be associated with  Aneuploidy (down syndrome or turner syndrome)  Congenital heart disease  Noonan syndrome  Miscarriage
  • 30. 31
  • 31. Heterotrophic pregnancy Heterotrophic pregnancy is a rare condition when there is an intrauterine and extrauterine pregnancy(i.e. ectopic pregnancy) occurring simultaneously 32
  • 32. 33
  • 33. 34
  • 34. 35

Editor's Notes

  1. Fertilization of the ovum occurs in the fallopian tube It starts cell division as it moves down the fallopian tube Once gets into the uterine cavity, it digs hole and borrows itself into the endometrium eccentrically and covers itself over This is the first sign that we look in usg which is called intradecidual sac sign
  2. Tvs
  3. Which usually located at the endometrium myometrium junction
  4. Visualization of yolk sac is useful in distinguishing intrauterine pregnancy from a pseudogestational sac Calcified or thick walled yolk sac is abnormal and may be associated with pregnancy failure Amnion develops embryoligically before yolk sac but yolk sac is easier to see
  5. Fetal cardiac activity is present when crl is more than 5mm
  6. Msd is a sonographic measurement of the GS which is usually seen at around 5 wks after the last menstural period Msd is calculated by measuring the anechoic sac excluding the echogenic rim
  7. As soon the embryo can be seen the GA can be estimated by measuring the crl Measure gestational age by CRL when CRL > 7mm
  8. If there is multiple gestations , It is imp to determine chorionicity as early as possible The chorion forms thick echogenic rim that completely encompasses the embyo If more than one embryo is seen within a single chorionic rim then the pregnancy is monochorionic, The next step is to determine amniocity ,but the amnion is very thin to be seen in early gestation However the no of yolk sacs parallels the no of amnions If there are two embryos and two yolk sac it is highly likely that the pregnancy is monochorionic diamniotic twin gestation
  9. Usg image of missed miscarriage Tvs shows a GS Embyo present crl 11mm Embryonic heart action absent suggestive of missed miscrriage
  10. Usg shows echogenic retained products of conception in endometrial cavity with internal vascularity on color doppler
  11. usg images of a pt presented with amenorrhea,pelvic pain and positive Bhcg Usg image showing Empty endometrial cavity Extrauterine right adnexal single gestational sac, single embryo suggestive of ectopic pregnancy CRL 18 mm There is anechoic free fluid in thepelvis
  12. There is empty endometrial cavity There is extrauterine leftsingle gestational sac with single yolk sac and single embryo with cardiac activity Crl 23.1 mm corresponding to 9 w 0 d Both ovaries are normal There is mild anechoic free fluid in pelvis
  13. Numerous small cystic spaces the “the cluster if grapes sign” is typical feature of molar pregnancy Gravid uterus with irregular GS containing embryo The placenta is thickened with multiple small cystic spaces inside and increased vascularity
  14. Nuchal translucency should be strictly < 3mm by standardized measuring technique use the correct technique The fetus must be in the mid sagittal imaging plane The fetal head should not be extended or flexed Magnification so that the fetal head and upper thorax are included Only the lucency and widest part is measured
  15. Often the intrauterine pregnancy is discovered later than the ectopic,mainly because of the painful emergency nature of ectopic pregnancy
  16. Usg image showing two gestational pregnancies,(both with fetal cardiac activity.) The intrauterine G.sac can be seen with a decidual reaction circumferentially around it. The other G.sac is located in the right adnexal region ,consistent with ectopic pregnancy.