The opening sequences of Trainspotting and 28 Days Later introduce their main characters in different ways. Trainspotting introduces most of its large group of characters, while 28 Days Later focuses on a single character escaping from a hospital. Both openings suggest the main characters are unhealthy, though for different reasons - drugs in Trainspotting and an unknown hospitalization in 28 Days Later. The sequences set different tones through their pacing, music, and portrayal of their settings.