4. Site for fertilization
Fertilization of ovum occurs in the ampulla or lateral 1/3rd
of uterine tube
Time of fertilization
It take place with the time period 24-48 hr
5. Important event of fertilization
Spermatozoon transport
1 semen
2 Transport of sperm
Capacitation
> Trans port of ovum.
> Acrosomal reaction.
6. Important event of fertilization
Spermatozoon transport
-play inportant role in fertilization
1. semen known as seminalfluid
7. Important event of fertilization
Spermatozoon transport
-play inportant role in fertilization
1. semen known as seminalfluid
60%
Seminal vesicles
-rich in fructose
-provide energy
For spermatozoa
8. Important event of fertilization
Spermatozoon transport
-play inportant role in fertilization
1. semen known as seminalfluid
60%
Seminal vesicles
-rich in fructose
-provide energy
For spermatozoa
25%
Prostate
Secertion of
Prostate Is :
Ion, citric acid,
phosphate
Fibrinogen
9. Important event of fertilization
Spermatozoon transport
-play inportant role in fertilization
1. semen known as seminalfluid
60%
Seminal vesicles
-rich in fructose
-provide energy
For spermatozoa
25%
Prostate
Secertion of
Prostate Is :
Ion, citric acid,
phosphate
Fibrinogen
5%
Bulboutheral
gland
Or Cowper gland
Secretion of this
gland
Acts as pre
ejaculatory
lubricant
10. Important event of fertilization
Spermatozoon transport
-play inportant role in fertilization
1. semen known as seminalfluid
60%
Seminal vesicles
-rich in fructose
-provide energy
For spermatozoa
25%
Prostate
Secertion of
Prostate Is :
Ion, citric acid,
phosphate
Fibrinogen
5%
Bulboutheral
gland
Or Cowper gland
Secretion of this
gland
Acts as pre
ejaculatory
lubricant
10%
Spermatozoa
Number of
spermatozoa
Released in each
ejaculation
40-100 million /ml
11. Important event of fertilization
Spermatozoon transport
1 semen
2 Transport of sperm:-
- prostaglandin +nt in semen stimulate
Peristaltic contraction of female genital
tract during sexual intercources
- Time taken for transport of sperm to
uterus is 5-45 minutes
12. Important event of fertilization
Spermatozoon transport
1 semen
2 Transport of sperm
Capacitation :-
In female reproductive tract the sperm
Were enabled to bind zona pelucida
receptor .the change are facilitated by
removal of Glycoprotien which cover sperm
13. Trans port of ovum:- transport of ovum from ovary to
ampulla of uterine tube viability of sperm are important
for succeses of fertilization.
a. Structure of ovum at ovulation:-
- contain sec. oocyte
- 23 unpair chromosome
- surrounded by zona pellucida with protein
&corona radiata
b. Transport of ovum from ovary to ampulla of
uterine tube:--
- the ovum reaches ampulla, the site of
fertilization in 25 minutes
c. Viability of ovum :-
- released at ovulation is viable for 24-48 hr
Enclosed vitelline membrane
14. Acrosomal reaction:- the release of acrosomal
enzyme (hyaluronidase,protease enzyme acrosin
And acid phosphatase )
that facilitate pentration of the zona pellucida
15. Imortant steps in fertilization
. passage of sperm through crona radiata:-
Crona radita 1st barrier digested by hyaluronidase.
. Pentration of zona pellucida: -
Zona pellucida have glycoprotein responsible
For induction of acrosomal reaction.
. Farmation female pronucleus :-
Reconstitution of oocyte chromosome forms
female pronucleus.
. Farmation male pronucleus :- the sperm head
makes a rotation of 180 within the oocyte cytoplaasm with
its nucleus swollen,transforms into male pronucleus
16.
17. Imortant steps in fertilization
. Farmation of zygote:-
Each chromosome in male and female pronuclei is
madeup of only one chromatid. DNA replication
take place to form 2nd chromatid in each
chromosome and 2 centriole appear .
Disappear of nuclear
Membrane and splitting
Of each chromosome into
Two (as in mitosis )occurs
The ovum now called
ZYGOTE