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BY
SANJAY KUMAR
Site for fertilization
Fertilization of ovum occurs in the ampulla or lateral 1/3rd
of uterine tube
Time of fertilization
It take place with the time period 24-48 hr
Important event of fertilization
Spermatozoon transport
1 semen
2 Transport of sperm
Capacitation
> Trans port of ovum.
> Acrosomal reaction.
Important event of fertilization
Spermatozoon transport
-play inportant role in fertilization
1. semen known as seminalfluid
Important event of fertilization
Spermatozoon transport
-play inportant role in fertilization
1. semen known as seminalfluid
60%
Seminal vesicles
-rich in fructose
-provide energy
For spermatozoa
Important event of fertilization
Spermatozoon transport
-play inportant role in fertilization
1. semen known as seminalfluid
60%
Seminal vesicles
-rich in fructose
-provide energy
For spermatozoa
25%
Prostate
Secertion of
Prostate Is :
Ion, citric acid,
phosphate
Fibrinogen
Important event of fertilization
Spermatozoon transport
-play inportant role in fertilization
1. semen known as seminalfluid
60%
Seminal vesicles
-rich in fructose
-provide energy
For spermatozoa
25%
Prostate
Secertion of
Prostate Is :
Ion, citric acid,
phosphate
Fibrinogen
5%
Bulboutheral
gland
Or Cowper gland
Secretion of this
gland
Acts as pre
ejaculatory
lubricant
Important event of fertilization
Spermatozoon transport
-play inportant role in fertilization
1. semen known as seminalfluid
60%
Seminal vesicles
-rich in fructose
-provide energy
For spermatozoa
25%
Prostate
Secertion of
Prostate Is :
Ion, citric acid,
phosphate
Fibrinogen
5%
Bulboutheral
gland
Or Cowper gland
Secretion of this
gland
Acts as pre
ejaculatory
lubricant
10%
Spermatozoa
Number of
spermatozoa
Released in each
ejaculation
40-100 million /ml
Important event of fertilization
Spermatozoon transport
1 semen
2 Transport of sperm:-
- prostaglandin +nt in semen stimulate
Peristaltic contraction of female genital
tract during sexual intercources
- Time taken for transport of sperm to
uterus is 5-45 minutes
Important event of fertilization
Spermatozoon transport
1 semen
2 Transport of sperm
Capacitation :-
In female reproductive tract the sperm
Were enabled to bind zona pelucida
receptor .the change are facilitated by
removal of Glycoprotien which cover sperm
Trans port of ovum:- transport of ovum from ovary to
ampulla of uterine tube viability of sperm are important
for succeses of fertilization.
a. Structure of ovum at ovulation:-
- contain sec. oocyte
- 23 unpair chromosome
- surrounded by zona pellucida with protein
&corona radiata
b. Transport of ovum from ovary to ampulla of
uterine tube:--
- the ovum reaches ampulla, the site of
fertilization in 25 minutes
c. Viability of ovum :-
- released at ovulation is viable for 24-48 hr
Enclosed vitelline membrane
Acrosomal reaction:- the release of acrosomal
enzyme (hyaluronidase,protease enzyme acrosin
And acid phosphatase )
that facilitate pentration of the zona pellucida
Imortant steps in fertilization
. passage of sperm through crona radiata:-
Crona radita 1st barrier digested by hyaluronidase.
. Pentration of zona pellucida: -
Zona pellucida have glycoprotein responsible
For induction of acrosomal reaction.
. Farmation female pronucleus :-
Reconstitution of oocyte chromosome forms
female pronucleus.
. Farmation male pronucleus :- the sperm head
makes a rotation of 180 within the oocyte cytoplaasm with
its nucleus swollen,transforms into male pronucleus
Imortant steps in fertilization
. Farmation of zygote:-
Each chromosome in male and female pronuclei is
madeup of only one chromatid. DNA replication
take place to form 2nd chromatid in each
chromosome and 2 centriole appear .
Disappear of nuclear
Membrane and splitting
Of each chromosome into
Two (as in mitosis )occurs
The ovum now called
ZYGOTE
FERTILIZATION embryology  by sanjay kumar .ppsx

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FERTILIZATION embryology by sanjay kumar .ppsx

  • 2.
  • 3.
  • 4. Site for fertilization Fertilization of ovum occurs in the ampulla or lateral 1/3rd of uterine tube Time of fertilization It take place with the time period 24-48 hr
  • 5. Important event of fertilization Spermatozoon transport 1 semen 2 Transport of sperm Capacitation > Trans port of ovum. > Acrosomal reaction.
  • 6. Important event of fertilization Spermatozoon transport -play inportant role in fertilization 1. semen known as seminalfluid
  • 7. Important event of fertilization Spermatozoon transport -play inportant role in fertilization 1. semen known as seminalfluid 60% Seminal vesicles -rich in fructose -provide energy For spermatozoa
  • 8. Important event of fertilization Spermatozoon transport -play inportant role in fertilization 1. semen known as seminalfluid 60% Seminal vesicles -rich in fructose -provide energy For spermatozoa 25% Prostate Secertion of Prostate Is : Ion, citric acid, phosphate Fibrinogen
  • 9. Important event of fertilization Spermatozoon transport -play inportant role in fertilization 1. semen known as seminalfluid 60% Seminal vesicles -rich in fructose -provide energy For spermatozoa 25% Prostate Secertion of Prostate Is : Ion, citric acid, phosphate Fibrinogen 5% Bulboutheral gland Or Cowper gland Secretion of this gland Acts as pre ejaculatory lubricant
  • 10. Important event of fertilization Spermatozoon transport -play inportant role in fertilization 1. semen known as seminalfluid 60% Seminal vesicles -rich in fructose -provide energy For spermatozoa 25% Prostate Secertion of Prostate Is : Ion, citric acid, phosphate Fibrinogen 5% Bulboutheral gland Or Cowper gland Secretion of this gland Acts as pre ejaculatory lubricant 10% Spermatozoa Number of spermatozoa Released in each ejaculation 40-100 million /ml
  • 11. Important event of fertilization Spermatozoon transport 1 semen 2 Transport of sperm:- - prostaglandin +nt in semen stimulate Peristaltic contraction of female genital tract during sexual intercources - Time taken for transport of sperm to uterus is 5-45 minutes
  • 12. Important event of fertilization Spermatozoon transport 1 semen 2 Transport of sperm Capacitation :- In female reproductive tract the sperm Were enabled to bind zona pelucida receptor .the change are facilitated by removal of Glycoprotien which cover sperm
  • 13. Trans port of ovum:- transport of ovum from ovary to ampulla of uterine tube viability of sperm are important for succeses of fertilization. a. Structure of ovum at ovulation:- - contain sec. oocyte - 23 unpair chromosome - surrounded by zona pellucida with protein &corona radiata b. Transport of ovum from ovary to ampulla of uterine tube:-- - the ovum reaches ampulla, the site of fertilization in 25 minutes c. Viability of ovum :- - released at ovulation is viable for 24-48 hr Enclosed vitelline membrane
  • 14. Acrosomal reaction:- the release of acrosomal enzyme (hyaluronidase,protease enzyme acrosin And acid phosphatase ) that facilitate pentration of the zona pellucida
  • 15. Imortant steps in fertilization . passage of sperm through crona radiata:- Crona radita 1st barrier digested by hyaluronidase. . Pentration of zona pellucida: - Zona pellucida have glycoprotein responsible For induction of acrosomal reaction. . Farmation female pronucleus :- Reconstitution of oocyte chromosome forms female pronucleus. . Farmation male pronucleus :- the sperm head makes a rotation of 180 within the oocyte cytoplaasm with its nucleus swollen,transforms into male pronucleus
  • 16.
  • 17. Imortant steps in fertilization . Farmation of zygote:- Each chromosome in male and female pronuclei is madeup of only one chromatid. DNA replication take place to form 2nd chromatid in each chromosome and 2 centriole appear . Disappear of nuclear Membrane and splitting Of each chromosome into Two (as in mitosis )occurs The ovum now called ZYGOTE