Poliomyelitis, or polio, is a viral disease that was once a serious public health threat. While most who contract the poliovirus experience mild or no symptoms, it can also cause paralysis or death. In the early 20th century, annual polio epidemics devastated communities before the Salk vaccine was introduced in the 1950s. The vaccine dramatically reduced polio cases worldwide and is one of the greatest medical advances in history. However, continued vaccination efforts are still needed to fully eradicate the disease.
Dbq Essay On Polio
Polio Essay
Polio Summary
Post Polio Research Paper
The Polio Vaccine Essay
Polio Literature Review
Poliomyelitis Essay
Poliio Research Paper
The Global Eradication of Polio Essays
Informative Essay On Polio
Polio Virus Essay
Polio Research Paper
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A brief discussion about POLIO... Though WHO declare Bangladesh as a polio free country it had a lot of hazardous effects in the past and we were the most sufferer country among all the countries... We thank our Govt. without their help we could not be able to call ourselves a polio free country... In this document I try my best to give you all a clear concept...... Hope it'll help everyone.....
Dbq Essay On Polio
Polio Essay
Polio Summary
Post Polio Research Paper
The Polio Vaccine Essay
Polio Literature Review
Poliomyelitis Essay
Poliio Research Paper
The Global Eradication of Polio Essays
Informative Essay On Polio
Polio Virus Essay
Polio Research Paper
Essay on Polio Vaccine
Research Paper On Polio
Polio Research Paper
A brief discussion about POLIO... Though WHO declare Bangladesh as a polio free country it had a lot of hazardous effects in the past and we were the most sufferer country among all the countries... We thank our Govt. without their help we could not be able to call ourselves a polio free country... In this document I try my best to give you all a clear concept...... Hope it'll help everyone.....
The Roman Empire A Historical Colossus.pdfkaushalkr1407
The Roman Empire, a vast and enduring power, stands as one of history's most remarkable civilizations, leaving an indelible imprint on the world. It emerged from the Roman Republic, transitioning into an imperial powerhouse under the leadership of Augustus Caesar in 27 BCE. This transformation marked the beginning of an era defined by unprecedented territorial expansion, architectural marvels, and profound cultural influence.
The empire's roots lie in the city of Rome, founded, according to legend, by Romulus in 753 BCE. Over centuries, Rome evolved from a small settlement to a formidable republic, characterized by a complex political system with elected officials and checks on power. However, internal strife, class conflicts, and military ambitions paved the way for the end of the Republic. Julius Caesar’s dictatorship and subsequent assassination in 44 BCE created a power vacuum, leading to a civil war. Octavian, later Augustus, emerged victorious, heralding the Roman Empire’s birth.
Under Augustus, the empire experienced the Pax Romana, a 200-year period of relative peace and stability. Augustus reformed the military, established efficient administrative systems, and initiated grand construction projects. The empire's borders expanded, encompassing territories from Britain to Egypt and from Spain to the Euphrates. Roman legions, renowned for their discipline and engineering prowess, secured and maintained these vast territories, building roads, fortifications, and cities that facilitated control and integration.
The Roman Empire’s society was hierarchical, with a rigid class system. At the top were the patricians, wealthy elites who held significant political power. Below them were the plebeians, free citizens with limited political influence, and the vast numbers of slaves who formed the backbone of the economy. The family unit was central, governed by the paterfamilias, the male head who held absolute authority.
Culturally, the Romans were eclectic, absorbing and adapting elements from the civilizations they encountered, particularly the Greeks. Roman art, literature, and philosophy reflected this synthesis, creating a rich cultural tapestry. Latin, the Roman language, became the lingua franca of the Western world, influencing numerous modern languages.
Roman architecture and engineering achievements were monumental. They perfected the arch, vault, and dome, constructing enduring structures like the Colosseum, Pantheon, and aqueducts. These engineering marvels not only showcased Roman ingenuity but also served practical purposes, from public entertainment to water supply.
Acetabularia Information For Class 9 .docxvaibhavrinwa19
Acetabularia acetabulum is a single-celled green alga that in its vegetative state is morphologically differentiated into a basal rhizoid and an axially elongated stalk, which bears whorls of branching hairs. The single diploid nucleus resides in the rhizoid.
Francesca Gottschalk - How can education support child empowerment.pptxEduSkills OECD
Francesca Gottschalk from the OECD’s Centre for Educational Research and Innovation presents at the Ask an Expert Webinar: How can education support child empowerment?
Welcome to TechSoup New Member Orientation and Q&A (May 2024).pdfTechSoup
In this webinar you will learn how your organization can access TechSoup's wide variety of product discount and donation programs. From hardware to software, we'll give you a tour of the tools available to help your nonprofit with productivity, collaboration, financial management, donor tracking, security, and more.
A Strategic Approach: GenAI in EducationPeter Windle
Artificial Intelligence (AI) technologies such as Generative AI, Image Generators and Large Language Models have had a dramatic impact on teaching, learning and assessment over the past 18 months. The most immediate threat AI posed was to Academic Integrity with Higher Education Institutes (HEIs) focusing their efforts on combating the use of GenAI in assessment. Guidelines were developed for staff and students, policies put in place too. Innovative educators have forged paths in the use of Generative AI for teaching, learning and assessments leading to pockets of transformation springing up across HEIs, often with little or no top-down guidance, support or direction.
This Gasta posits a strategic approach to integrating AI into HEIs to prepare staff, students and the curriculum for an evolving world and workplace. We will highlight the advantages of working with these technologies beyond the realm of teaching, learning and assessment by considering prompt engineering skills, industry impact, curriculum changes, and the need for staff upskilling. In contrast, not engaging strategically with Generative AI poses risks, including falling behind peers, missed opportunities and failing to ensure our graduates remain employable. The rapid evolution of AI technologies necessitates a proactive and strategic approach if we are to remain relevant.
Model Attribute Check Company Auto PropertyCeline George
In Odoo, the multi-company feature allows you to manage multiple companies within a single Odoo database instance. Each company can have its own configurations while still sharing common resources such as products, customers, and suppliers.
Read| The latest issue of The Challenger is here! We are thrilled to announce that our school paper has qualified for the NATIONAL SCHOOLS PRESS CONFERENCE (NSPC) 2024. Thank you for your unwavering support and trust. Dive into the stories that made us stand out!
Honest Reviews of Tim Han LMA Course Program.pptxtimhan337
Personal development courses are widely available today, with each one promising life-changing outcomes. Tim Han’s Life Mastery Achievers (LMA) Course has drawn a lot of interest. In addition to offering my frank assessment of Success Insider’s LMA Course, this piece examines the course’s effects via a variety of Tim Han LMA course reviews and Success Insider comments.
Synthetic Fiber Construction in lab .pptxPavel ( NSTU)
Synthetic fiber production is a fascinating and complex field that blends chemistry, engineering, and environmental science. By understanding these aspects, students can gain a comprehensive view of synthetic fiber production, its impact on society and the environment, and the potential for future innovations. Synthetic fibers play a crucial role in modern society, impacting various aspects of daily life, industry, and the environment. ynthetic fibers are integral to modern life, offering a range of benefits from cost-effectiveness and versatility to innovative applications and performance characteristics. While they pose environmental challenges, ongoing research and development aim to create more sustainable and eco-friendly alternatives. Understanding the importance of synthetic fibers helps in appreciating their role in the economy, industry, and daily life, while also emphasizing the need for sustainable practices and innovation.
2024 State of Marketing Report – by HubspotMarius Sescu
https://www.hubspot.com/state-of-marketing
· Scaling relationships and proving ROI
· Social media is the place for search, sales, and service
· Authentic influencer partnerships fuel brand growth
· The strongest connections happen via call, click, chat, and camera.
· Time saved with AI leads to more creative work
· Seeking: A single source of truth
· TLDR; Get on social, try AI, and align your systems.
· More human marketing, powered by robots
ChatGPT is a revolutionary addition to the world since its introduction in 2022. A big shift in the sector of information gathering and processing happened because of this chatbot. What is the story of ChatGPT? How is the bot responding to prompts and generating contents? Swipe through these slides prepared by Expeed Software, a web development company regarding the development and technical intricacies of ChatGPT!
The Roman Empire A Historical Colossus.pdfkaushalkr1407
The Roman Empire, a vast and enduring power, stands as one of history's most remarkable civilizations, leaving an indelible imprint on the world. It emerged from the Roman Republic, transitioning into an imperial powerhouse under the leadership of Augustus Caesar in 27 BCE. This transformation marked the beginning of an era defined by unprecedented territorial expansion, architectural marvels, and profound cultural influence.
The empire's roots lie in the city of Rome, founded, according to legend, by Romulus in 753 BCE. Over centuries, Rome evolved from a small settlement to a formidable republic, characterized by a complex political system with elected officials and checks on power. However, internal strife, class conflicts, and military ambitions paved the way for the end of the Republic. Julius Caesar’s dictatorship and subsequent assassination in 44 BCE created a power vacuum, leading to a civil war. Octavian, later Augustus, emerged victorious, heralding the Roman Empire’s birth.
Under Augustus, the empire experienced the Pax Romana, a 200-year period of relative peace and stability. Augustus reformed the military, established efficient administrative systems, and initiated grand construction projects. The empire's borders expanded, encompassing territories from Britain to Egypt and from Spain to the Euphrates. Roman legions, renowned for their discipline and engineering prowess, secured and maintained these vast territories, building roads, fortifications, and cities that facilitated control and integration.
The Roman Empire’s society was hierarchical, with a rigid class system. At the top were the patricians, wealthy elites who held significant political power. Below them were the plebeians, free citizens with limited political influence, and the vast numbers of slaves who formed the backbone of the economy. The family unit was central, governed by the paterfamilias, the male head who held absolute authority.
Culturally, the Romans were eclectic, absorbing and adapting elements from the civilizations they encountered, particularly the Greeks. Roman art, literature, and philosophy reflected this synthesis, creating a rich cultural tapestry. Latin, the Roman language, became the lingua franca of the Western world, influencing numerous modern languages.
Roman architecture and engineering achievements were monumental. They perfected the arch, vault, and dome, constructing enduring structures like the Colosseum, Pantheon, and aqueducts. These engineering marvels not only showcased Roman ingenuity but also served practical purposes, from public entertainment to water supply.
Acetabularia Information For Class 9 .docxvaibhavrinwa19
Acetabularia acetabulum is a single-celled green alga that in its vegetative state is morphologically differentiated into a basal rhizoid and an axially elongated stalk, which bears whorls of branching hairs. The single diploid nucleus resides in the rhizoid.
Francesca Gottschalk - How can education support child empowerment.pptxEduSkills OECD
Francesca Gottschalk from the OECD’s Centre for Educational Research and Innovation presents at the Ask an Expert Webinar: How can education support child empowerment?
Welcome to TechSoup New Member Orientation and Q&A (May 2024).pdfTechSoup
In this webinar you will learn how your organization can access TechSoup's wide variety of product discount and donation programs. From hardware to software, we'll give you a tour of the tools available to help your nonprofit with productivity, collaboration, financial management, donor tracking, security, and more.
A Strategic Approach: GenAI in EducationPeter Windle
Artificial Intelligence (AI) technologies such as Generative AI, Image Generators and Large Language Models have had a dramatic impact on teaching, learning and assessment over the past 18 months. The most immediate threat AI posed was to Academic Integrity with Higher Education Institutes (HEIs) focusing their efforts on combating the use of GenAI in assessment. Guidelines were developed for staff and students, policies put in place too. Innovative educators have forged paths in the use of Generative AI for teaching, learning and assessments leading to pockets of transformation springing up across HEIs, often with little or no top-down guidance, support or direction.
This Gasta posits a strategic approach to integrating AI into HEIs to prepare staff, students and the curriculum for an evolving world and workplace. We will highlight the advantages of working with these technologies beyond the realm of teaching, learning and assessment by considering prompt engineering skills, industry impact, curriculum changes, and the need for staff upskilling. In contrast, not engaging strategically with Generative AI poses risks, including falling behind peers, missed opportunities and failing to ensure our graduates remain employable. The rapid evolution of AI technologies necessitates a proactive and strategic approach if we are to remain relevant.
Model Attribute Check Company Auto PropertyCeline George
In Odoo, the multi-company feature allows you to manage multiple companies within a single Odoo database instance. Each company can have its own configurations while still sharing common resources such as products, customers, and suppliers.
Read| The latest issue of The Challenger is here! We are thrilled to announce that our school paper has qualified for the NATIONAL SCHOOLS PRESS CONFERENCE (NSPC) 2024. Thank you for your unwavering support and trust. Dive into the stories that made us stand out!
Honest Reviews of Tim Han LMA Course Program.pptxtimhan337
Personal development courses are widely available today, with each one promising life-changing outcomes. Tim Han’s Life Mastery Achievers (LMA) Course has drawn a lot of interest. In addition to offering my frank assessment of Success Insider’s LMA Course, this piece examines the course’s effects via a variety of Tim Han LMA course reviews and Success Insider comments.
Synthetic Fiber Construction in lab .pptxPavel ( NSTU)
Synthetic fiber production is a fascinating and complex field that blends chemistry, engineering, and environmental science. By understanding these aspects, students can gain a comprehensive view of synthetic fiber production, its impact on society and the environment, and the potential for future innovations. Synthetic fibers play a crucial role in modern society, impacting various aspects of daily life, industry, and the environment. ynthetic fibers are integral to modern life, offering a range of benefits from cost-effectiveness and versatility to innovative applications and performance characteristics. While they pose environmental challenges, ongoing research and development aim to create more sustainable and eco-friendly alternatives. Understanding the importance of synthetic fibers helps in appreciating their role in the economy, industry, and daily life, while also emphasizing the need for sustainable practices and innovation.
2024 State of Marketing Report – by HubspotMarius Sescu
https://www.hubspot.com/state-of-marketing
· Scaling relationships and proving ROI
· Social media is the place for search, sales, and service
· Authentic influencer partnerships fuel brand growth
· The strongest connections happen via call, click, chat, and camera.
· Time saved with AI leads to more creative work
· Seeking: A single source of truth
· TLDR; Get on social, try AI, and align your systems.
· More human marketing, powered by robots
ChatGPT is a revolutionary addition to the world since its introduction in 2022. A big shift in the sector of information gathering and processing happened because of this chatbot. What is the story of ChatGPT? How is the bot responding to prompts and generating contents? Swipe through these slides prepared by Expeed Software, a web development company regarding the development and technical intricacies of ChatGPT!
Product Design Trends in 2024 | Teenage EngineeringsPixeldarts
The realm of product design is a constantly changing environment where technology and style intersect. Every year introduces fresh challenges and exciting trends that mold the future of this captivating art form. In this piece, we delve into the significant trends set to influence the look and functionality of product design in the year 2024.
How Race, Age and Gender Shape Attitudes Towards Mental HealthThinkNow
Mental health has been in the news quite a bit lately. Dozens of U.S. states are currently suing Meta for contributing to the youth mental health crisis by inserting addictive features into their products, while the U.S. Surgeon General is touring the nation to bring awareness to the growing epidemic of loneliness and isolation. The country has endured periods of low national morale, such as in the 1970s when high inflation and the energy crisis worsened public sentiment following the Vietnam War. The current mood, however, feels different. Gallup recently reported that national mental health is at an all-time low, with few bright spots to lift spirits.
To better understand how Americans are feeling and their attitudes towards mental health in general, ThinkNow conducted a nationally representative quantitative survey of 1,500 respondents and found some interesting differences among ethnic, age and gender groups.
Technology
For example, 52% agree that technology and social media have a negative impact on mental health, but when broken out by race, 61% of Whites felt technology had a negative effect, and only 48% of Hispanics thought it did.
While technology has helped us keep in touch with friends and family in faraway places, it appears to have degraded our ability to connect in person. Staying connected online is a double-edged sword since the same news feed that brings us pictures of the grandkids and fluffy kittens also feeds us news about the wars in Israel and Ukraine, the dysfunction in Washington, the latest mass shooting and the climate crisis.
Hispanics may have a built-in defense against the isolation technology breeds, owing to their large, multigenerational households, strong social support systems, and tendency to use social media to stay connected with relatives abroad.
Age and Gender
When asked how individuals rate their mental health, men rate it higher than women by 11 percentage points, and Baby Boomers rank it highest at 83%, saying it’s good or excellent vs. 57% of Gen Z saying the same.
Gen Z spends the most amount of time on social media, so the notion that social media negatively affects mental health appears to be correlated. Unfortunately, Gen Z is also the generation that’s least comfortable discussing mental health concerns with healthcare professionals. Only 40% of them state they’re comfortable discussing their issues with a professional compared to 60% of Millennials and 65% of Boomers.
Race Affects Attitudes
As seen in previous research conducted by ThinkNow, Asian Americans lag other groups when it comes to awareness of mental health issues. Twenty-four percent of Asian Americans believe that having a mental health issue is a sign of weakness compared to the 16% average for all groups. Asians are also considerably less likely to be aware of mental health services in their communities (42% vs. 55%) and most likely to seek out information on social media (51% vs. 35%).
AI Trends in Creative Operations 2024 by Artwork Flow.pdfmarketingartwork
This article is all about what AI trends will emerge in the field of creative operations in 2024. All the marketers and brand builders should be aware of these trends for their further use and save themselves some time!
A report by thenetworkone and Kurio.
The contributing experts and agencies are (in an alphabetical order): Sylwia Rytel, Social Media Supervisor, 180heartbeats + JUNG v MATT (PL), Sharlene Jenner, Vice President - Director of Engagement Strategy, Abelson Taylor (USA), Alex Casanovas, Digital Director, Atrevia (ES), Dora Beilin, Senior Social Strategist, Barrett Hoffher (USA), Min Seo, Campaign Director, Brand New Agency (KR), Deshé M. Gully, Associate Strategist, Day One Agency (USA), Francesca Trevisan, Strategist, Different (IT), Trevor Crossman, CX and Digital Transformation Director; Olivia Hussey, Strategic Planner; Simi Srinarula, Social Media Manager, The Hallway (AUS), James Hebbert, Managing Director, Hylink (CN / UK), Mundy Álvarez, Planning Director; Pedro Rojas, Social Media Manager; Pancho González, CCO, Inbrax (CH), Oana Oprea, Head of Digital Planning, Jam Session Agency (RO), Amy Bottrill, Social Account Director, Launch (UK), Gaby Arriaga, Founder, Leonardo1452 (MX), Shantesh S Row, Creative Director, Liwa (UAE), Rajesh Mehta, Chief Strategy Officer; Dhruv Gaur, Digital Planning Lead; Leonie Mergulhao, Account Supervisor - Social Media & PR, Medulla (IN), Aurelija Plioplytė, Head of Digital & Social, Not Perfect (LI), Daiana Khaidargaliyeva, Account Manager, Osaka Labs (UK / USA), Stefanie Söhnchen, Vice President Digital, PIABO Communications (DE), Elisabeth Winiartati, Managing Consultant, Head of Global Integrated Communications; Lydia Aprina, Account Manager, Integrated Marketing and Communications; Nita Prabowo, Account Manager, Integrated Marketing and Communications; Okhi, Web Developer, PNTR Group (ID), Kei Obusan, Insights Director; Daffi Ranandi, Insights Manager, Radarr (SG), Gautam Reghunath, Co-founder & CEO, Talented (IN), Donagh Humphreys, Head of Social and Digital Innovation, THINKHOUSE (IRE), Sarah Yim, Strategy Director, Zulu Alpha Kilo (CA).
Trends In Paid Search: Navigating The Digital Landscape In 2024Search Engine Journal
The search marketing landscape is evolving rapidly with new technologies, and professionals, like you, rely on innovative paid search strategies to meet changing demands.
It’s important that you’re ready to implement new strategies in 2024.
Check this out and learn the top trends in paid search advertising that are expected to gain traction, so you can drive higher ROI more efficiently in 2024.
You’ll learn:
- The latest trends in AI and automation, and what this means for an evolving paid search ecosystem.
- New developments in privacy and data regulation.
- Emerging ad formats that are expected to make an impact next year.
Watch Sreekant Lanka from iQuanti and Irina Klein from OneMain Financial as they dive into the future of paid search and explore the trends, strategies, and technologies that will shape the search marketing landscape.
If you’re looking to assess your paid search strategy and design an industry-aligned plan for 2024, then this webinar is for you.
5 Public speaking tips from TED - Visualized summarySpeakerHub
From their humble beginnings in 1984, TED has grown into the world’s most powerful amplifier for speakers and thought-leaders to share their ideas. They have over 2,400 filmed talks (not including the 30,000+ TEDx videos) freely available online, and have hosted over 17,500 events around the world.
With over one billion views in a year, it’s no wonder that so many speakers are looking to TED for ideas on how to share their message more effectively.
The article “5 Public-Speaking Tips TED Gives Its Speakers”, by Carmine Gallo for Forbes, gives speakers five practical ways to connect with their audience, and effectively share their ideas on stage.
Whether you are gearing up to get on a TED stage yourself, or just want to master the skills that so many of their speakers possess, these tips and quotes from Chris Anderson, the TED Talks Curator, will encourage you to make the most impactful impression on your audience.
See the full article and more summaries like this on SpeakerHub here: https://speakerhub.com/blog/5-presentation-tips-ted-gives-its-speakers
See the original article on Forbes here:
http://www.forbes.com/forbes/welcome/?toURL=http://www.forbes.com/sites/carminegallo/2016/05/06/5-public-speaking-tips-ted-gives-its-speakers/&refURL=&referrer=#5c07a8221d9b
ChatGPT and the Future of Work - Clark Boyd Clark Boyd
Everyone is in agreement that ChatGPT (and other generative AI tools) will shape the future of work. Yet there is little consensus on exactly how, when, and to what extent this technology will change our world.
Businesses that extract maximum value from ChatGPT will use it as a collaborative tool for everything from brainstorming to technical maintenance.
For individuals, now is the time to pinpoint the skills the future professional will need to thrive in the AI age.
Check out this presentation to understand what ChatGPT is, how it will shape the future of work, and how you can prepare to take advantage.
A brief introduction to DataScience with explaining of the concepts, algorithms, machine learning, supervised and unsupervised learning, clustering, statistics, data preprocessing, real-world applications etc.
It's part of a Data Science Corner Campaign where I will be discussing the fundamentals of DataScience, AIML, Statistics etc.
Time Management & Productivity - Best PracticesVit Horky
Here's my presentation on by proven best practices how to manage your work time effectively and how to improve your productivity. It includes practical tips and how to use tools such as Slack, Google Apps, Hubspot, Google Calendar, Gmail and others.
The six step guide to practical project managementMindGenius
The six step guide to practical project management
If you think managing projects is too difficult, think again.
We’ve stripped back project management processes to the
basics – to make it quicker and easier, without sacrificing
the vital ingredients for success.
“If you’re looking for some real-world guidance, then The Six Step Guide to Practical Project Management will help.”
Dr Andrew Makar, Tactical Project Management
Beginners Guide to TikTok for Search - Rachel Pearson - We are Tilt __ Bright...
Fear Of Polio Essay
1. Fear of Polio Essay
Fear Of The Unknown
GMO Products
Parents and children today may have no memory of the dreaded disease called polio, which struck both young and old by the score from the 1930s to
the 1950s. School children and parents were as frightened of polio as they were of nuclear bomb attacks on the United States.
When the polio vaccine was finally discovered, people all over America were inoculated. Still, there were scores of people who did not trust doctors,
did not like the use of needles – and some who even feared that the vaccine would give their child polio. Anti–vaccine propaganda and rumors were
spread to the public. Some of the unvaccinated number continued to contract the crippling and deadly disease. But occurrence of polio is almost,...show
more content...
GMO seemed a great way to build trade barriers to U.S. imports – and help European agriculture and agribusiness to sell more of their products at
home and abroad.
European consumers continue to question the reliability of food safety and oversight provided by food ministry departments in various European
countries. Their fear is based on real experiences that happened in the last decade.
Contaminated beef, originating in Britain and exported to other EU countries, resulted in human fatalities. Blame was placed squarely on the shoulders
of government scientists and food safety experts. (Lack of trust continues today.)
In truth, people have been eating products made with GMO commodities for several years now – with no ill effects. Years of testing went into the
development of GMO seed, which allows farmers to use fewer pesticides and herbicides on crops, and so increase net income. For consumers who
remain unsure about the safety of crop protection chemicals, eating GMO foods should actually be reassuring news about the safety of the U.S. food
supply.
The list of endorsements and approval of GMO foods goes all the way up to the Commander in Chief, President Bill Clinton. The President recently
proposed greater government oversight of GMO food production and manufacturing, in hopes of increasing consumer confidence in the safety of these
foods. NC Governor Jim Hunt, concerned that public opposition to GMO could affect farmers in
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2. The Polio Vaccine Essay
The Polio Vaccine
The discovery of the polio vaccine was an important medical and scientific breakthrough because it saved many lives since the 1950s. In the summer
of 1916 the great polio epidemic struck the United states. By the 1950s hundreds of thousands of people had been struck by the poliomyelitis. The
highest number of cases occurred in 1953 with over 50,000 people infected with the virus. When hygienic conditions were poor polio attacked infants.
The disease was spread by contaminated water and contact with fecal contamination. Many infants died when the conditions were poor. But as
conditions improved the virus spread differently. It was spread more through playmates and family members, the contamination came from the...show
more content...
Dean William McEllroy talked Salk into joining the university full–time. Though the school's research budget was a grant from the American Society
for the Study of High Blood Pressure in the amount of $1,800, he saw the opportunity to do two things. One was to continue the work he was
doing on influenza, second was to begin working with the polio virus. A few months after arriving in Pittsburgh, Salk was visited by the director
of research at the National Foundation for Infantile Paralysis. The director asked Salk if he would be willing to participate in a polio typing
program. "I had no experience working with polio, but it provided me with an opportunity. . ." Salk said in an interview. This gave Salk a chance to
get funding, equipment, a laboratory facility, and to hire a staff to work for and with him. Salk's previous work gave him the idea that a killed virus
could in fact work when others thought it couldn't. To type the polio virus Salk infected monkeys with polio by injecting it into them or feeding it to
them. If a monkey survived it built up antibodies to protect against the virus. The monkeys that survived were then given another type of virus to see if
the same antibodies protected against the second type. If it did, it told Salk and his assistants that the two types were related. If it did not, that told Salk
that they were not related. Eventually
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3. Polio Research Paper
Polio is an infectious disease caused by a special types of viruses. The United States Of America is still at risk of introducing polio. A polio like illness
has recently been discovered in California in children that produces paralysis like in some polio patients. The last case of polio in The United States Of
America was in 1979. Polio is still a very high problem in Africa and Asia. Polio has also been traced back almost 6,000 years ago.
Polio is caused by small viruses, RNA viruses to be exact. The viruses are members enterovirus group of the Picornavirus family. The polio virus is
known to attack the nervous system. There are 3 different types of polio viruses. Type one is responsible for about 85% of all paralytic infections.
...show more content...
One of the main symptoms is muscle weakness and/or tiredness. Another symptom would be vomiting. Another symptom is fatigue Also another
symptom can possibly be joint pain. The rest of the symptoms are headaches, nausea, fever, and sore throat.
If you already have polio there is no cure for it. If you take polio prevention vaccines. There are three different types of vaccines. If you take theses
vaccines the viruses could mutate. If the virus mutates to where the vaccine doesn't work polio can possibly kill you even faster. You mainly want to
make sure that your kids and parents are vaccinated because they are most likely to get polio and not survive.
Here are a couple more facts about polio that you might not know. Up to 90% of polio cases don't even have symptoms. One in two–hundred people
get paralysis from this disease. Five to ten percent of paralyzed patients die. The viruses is found in saliva and feces of all of the patients that have
polio. Children five and under makeup for 50% of the polio cases but any age of people can get polio. Polio cases have decreased more than 99% since
1988. Polio went from having three–hundred and fifty thousand to only four hundred and sixteen. The first polio vaccine was made by Jonas Salk in
1952 to try to prevent polio since there is no
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4. Polio Virus
Peter Hughes Mrs. Lowory Biology, Period 7 February 27, 2016 Poliomyelitis Poliomyelitis or more commonly known as polio is a viral disease.
The Polio virus can fly under the radar for a while, but later the effects may show. In many cases a person may have polio but it will never affect
them. The name of the virus that causes polio is the "poliovirus" it spreads extremely easily in unsanitary areas due to human waste being in the
water. If someone develops polio and suffer the they will suffer from paralysis which may be fatal in some cases. It will cause the victim to feel great
pain and weakness in their muscles and joints. It will especially attack the victim's spine and limbs. This will only get worse over time due to the
disease....show more content...
Sub clinical polio symptoms include headaches, sore throat, vomiting and fevers. Non paralytic polio symptoms include sore throat, fever,
vomiting, fatigue, slow reflexes, hard time breathing, back pain, neck pain, arm pain, leg pain, and muscle spasms. Paralytic polio symptoms
include slow to no reflexes, immense muscle pain, frequent muscle spasms, loss of movement in limbs, limbs become weak and deformed.
Usually people develop sub clinical polio which is barely noticeable and symptoms may not even show. The next most common form is non
paralytic polio which is less likely to be contracted but is more serious but symptoms are not severe. The rarest kind is paralytic polio it affects the
spinal and brain stem. Paralytic polio is extremely painful. It can cause death by weakening the muscles that helps one breath. Polio can not be
cured but it can be treated and even prevented. But the treatment will cost a decent amount of money and resources. This is why many second and
third world countries have polio issues since they can't afford it. The treatment for polio may include "Iron Lungs" since the muscles in the lungs
may fail this would help the person stay alive. This was originally a problem since only so many could have an iron lung so the doctors had to decide
who would be
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5. Polio Essay
Poliomyelitis Poliomyelitis (more commonly known as polio) is a highly infectious disease, in which it affect the cells in the central nervous system
(CNS). It mainly affect young children, mostly under the age of 5. Afghanistan and Pakistan are the only countries which have polio present within the
population. Polio virus is most commonly found in area with low standards of sanitation. It spreads through faecal–oral transmission or through
contaminated food and water. The polio virus works by replicating the motor neurons in the CNS and then destroying the original motor neuron cells.
The virus manifests itself in the throat and the intestines, where the virus multiplies and spreads to other parts of the body through the use of the
bloodstream....show more content...
In cases of non–paralytic polio, the body doesn't become paralytic but, there may be acute stiffness in the arms and legs. Non–paralytic polio may
include symptoms like; fever, sore throat, headache, nausea and vomiting, fatigue, pain in the back and neck, stiffness in the arms and legs, muscle
tenderness, spasms and in some of the worst cases meningitis which is an infection of the membranes surrounding the brain. There are three types of
paralytic polio, spinal, bulbar and bulbospinal. Spinal Polio attacks the motor neurons in the spinal cord which results in paralysis in the arm and
legs, it can also cause breathing problems. Bulbar Polio affects the medulla oblongata, a muscle in the brain responsible for breathing, heart rate. It can
lead to problematic health issues such as poor eyesight, difficulty in swallowing and respiratory issues like breathing problems. Bulbospinal Polio
includes both the symptoms spinal and bulbar polio. There are also cases of Post–Polio Syndrome which is a cluster of symptoms that affect up to
50% of all polio patients. On average, the syndrome occurs 35 years after the infection. Symptoms of post–polio syndrome include; muscle and joint
pain that progress throughout the body, muscle atrophy which is shrinking muscle volume, unexplained exhaustion and swallowing and breathing
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6. The Polio Vaccine
The CDC, Center for Disease Control, says that polio used to be very common in the United States Before the polio vaccine and that it infected
thousands of people each year with this severe illness. This outbreak stopped with the invention of the polio vaccine in 1955. In this essay we will
discuss what polio is, how effected our world, and how the vaccine stopped the outbreak.
Polio, or poliomyelitis, is a crippling and sometimes deadly infectious disease states the CDC. The disease can invade a person's brain and spinal cord.
This can cause paralysis, where a person can't move parts of their body. According to the CDC most people who get infected with poliovirus will not
have any visible symptoms – about 72 out of 100 people. The CDC also states that one out of four people with poliovirus will have flu–like
symptoms. A smaller portion of people could develop more serious symptoms that effect the brain and spinal cord. These symptoms could include:
paresthesia or feeling...show more content...
The NMAH also, states that a person who gets the polio vaccine is immune to future infection. Jonas Salk and Albert Sabin used this knowledge, that
vaccines work by fooling the body's immune system into producing antibodies even when there is no disease, to create two different kinds of polio
vaccines. The vaccine created by Jonas Salk was the leading proponent of the killed, or inactive virus. Albert Sabin was the foremost proponent of
the attenuated, or weakened virus vaccine. Both of these vaccines have been proven to work for years. There was a study done in 1952 that lead to
Salk's Vaccine being named in 1954. During this time Sabin was still creating his live–virus, or weekend, vaccine. NMSH also states that IPV, or Salk's
vaccine is an injected shot used primarily today in the US and in Europe. OPV, or Sabin's vaccine is given orally in drop firm and is used in global
efforts to stop polio
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7. Essay on Polio Vaccine
Poliomyelitis (shortened to polio) has been around for thousands of years, and there is still no cure, but at the peak of its devastation in the United
States, Dr. Jonas Salk introduced a way to prevent it. Polio attacks the nerve cells and sometimes the central nervous system, causing muscle wasting,
paralysis, and even death. The disease, whose symptoms are flu like, stuck mostly children, and in the first half of the 20th century the epidemics of
polio were becoming more devastating. Salk, while working at the Virus Research
Lab at the University of Pittsburgh, developed a polio vaccine, and the medical trials to prove its effectiveness and safety are still being analyzed. Fifty
years ago the largest medical experiment in...show more content...
The use of the dual protocol illustrates both the power and the limitations of randomized clinical trials. The control trials with the placebo were
important to define the vaccine as the product of scientific medicine, while the observed trials were done to maintain public support for the vaccine. In
1953, Salk presented his tests of a polio vaccine to the Immunization
Committee, the scientific advisory committee for the NFIP. The test results seemed promising to Basil O'Connor, as the children had shown no ill
effects and the levels of polio antibodies in their blood had risen. However, several of the senior virologist on the committee questioned the relation of
antibodies to permanent immunity. Despite the virologist's critique, O'Connor believed that his organization owed it to the volunteers and donors to
proceed and called for the planning of a major field study. O'Connor, in November of 1953, announced that the field trials would begin in the spring and
the observed plan would be used. Within a month, health departments in 38 states had responded, enthusiastic about the prospect of a vaccine. A few
state officials however, questioned the impartiality of the evaluation run by the foundation, and not by scientists.
Responding to the criticism O'Connor called an meeting of an advisory group to review the statistical design. When the group convened, it had decided
to go strictly with the placebo controlled
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8. Polio Research Paper
Ocean County College
Department of Biology
The Poliovirus
Submitted By,
Stephen Gorda
Date Submitted: 5–2–12
Course: Biology– 162
Instructor: Prof. Estelle Abstract The poliovirus is one of the most transmittable and most contagious viruses that the human population has come in
contact with. The structure of the poliovirus allows it to be able to bind to motor neuron cells within a host's body and reproduce quickly. Like all
virus's, the poliovirus...show more content...
The similarity between the poliovirus and already solved plant virus's led to a better understanding of how the poliovirus can regenerate within a host.
Although the virus was similar to other plant viruses. The poliovirus was covered with more elaborate loops that are the site of monoclonal antibody
escape mutations (Hogle, Chow and 229: 1358–1365Filman, Science). Individual proteins of the virus particle are produced by proteolytic cleavages
from a larger precursor, yet the amino and carboxy–termini produced by proteolysis are very distinct. By noting this, Hogle and his team were able to
conclude that proteolysis was not just making a lot of proteins from one gene, it is also controlling the timing of assembly (Hogle, Chow and Filman,
Science 229: 1358–1365).
B. Signs and Symptoms: Approximately 95 percent of people who are infected with poliovirus will not have any symptoms, however, people who are
infected and do not have any polio indicators can still spread the poliovirus. People who become infected with the poliovirus can start having
symptoms as soon as four days after being infected, and not have any symptoms for as many as thirty five days. This time period between infection and
experiencing symptoms is referred to as "The Incubation Period," which is when the virus begins to multiply within the cells that line the back of the
throat, nose, and intestines("Signs and symptoms of Polio." eMedtv.com. Clinaero Inc., 2006–2012. Sunday 4–22–12). For the
10. Poliomyelitis Essay
Ancient Egyptian paintings and carvings narrate otherwise healthy people with withered limbs and children walking with the help of canes at a
young age.(1) It is theorized that the Roman Emperor, Claudius was suffered from poliomyelitis because of it, he walked with a limp for the rest of
his life. Earliest recorded case of poliomyelitis was that of Sir Walter Scott. In 1773 Scott was developed "a severe teething fever which disabled him of
paralysis of his right leg".( 2)
The symptoms of poliomyelitis had been described by many ways. In the early nineteenth century the disease was known as: Dental Paralysis,
Infantile Spinal cord Paralysis, Essential Paralysis of Children, Regressive Paralysis, myelitis of the Anterior Horns cells, Tephro...show more content...
It invades the human nervous system and can cause complete paralysis in a matter of hours. Humans are only reservoir. The virus is mostly transmitted
by person–to–person spread mainly through the fecal–oral route , less frequently, by a common vehicle for example, contaminated water or food.It
multiplies in the intestine. Initial symptoms are commonly fever, fatigue, headache, vomiting, stiffness of the neck and pain in the limbs. 1 in
200polio infections leads to irreversible paralysis. Among those paralyzed polio cases, 5% to 10% die of polio when their breathing muscles become
paralyzed. Polio mainly affects children under 5 years of age. There is no cure for polio paralysis, it can only be prevented with multiple doses of two
drops of polio
Major polio epidemics were unknown before the 20th century; localized paralytic polio epidemics began to appear in Europe and the United States
around 1900. The first report of multiple polio cases was published in 1843 and described an 1841 outbreak in Louisiana.(5)
On Saturday, June 17, 1916, an official announcement was made regarding existence of an epidemic polio infection in Brooklyn, New York. That year,
there were
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11. Research Paper On Polio
By 1910, a small epidemic of polio became regular especially in cities during the summer months. The disease was later called infantile paralysis,
based on its tendency to affect children. Polio is caused by one of three types of poliovirus. These viruses spread through contact between people, by
nasal and oral secretions, and by contact with contaminated feces. Poliovirus enters the body through the mouth, multiplying along the way to the
digestive tract, where it further multiplies. About 95% of all cases display no symptoms. When symptoms appear they are flu–like symptoms that last
for a few days or weeks, such as fever, sore throat, headache, vomiting, back and neck pain, arm and leg stiffness, muscle tenderness, and muscle
spasms. Polio is often recognized because of symptoms...show more content...
The 1952 polio epidemic became the worst outbreak, of the nearly 58,000 cases reported 3,145 died and 21,269 were left with mild to disabling
paralysis. Three years later, Dr. Jonas Salk from The University of Pittsburgh, became a national hero when he developed the first safe and effective
polio vaccine in 1955 with the support of the March of Dimes. In the two years before the vaccine was, widely available, the average number of
polio cases was more than 45,000. By 1962, that number had dropped to 910. By 1979, the virus had been completely eliminated across the country.
There is no cure for polio once a person becomes infected. Therefore, treatments include antibiotics, pain killers, ventilators to help breathing, and
moderate exercise. The disease can kill and remains incurable, but vaccines have assisted in almost total eradication in the world. Polio vaccination in
the United States is still recommended because of the risk of imported cases, children are recommended to receive the inactivated polio vaccine at 2
months and 4 months of age, and then twice more before entering elementary
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12. Polio Virus Essay
Polio Virus
Introduction
The polio virus which causes poliomyelitis in humans is an enterovirus which belongs to the picornavirus (small, RNA) family. Polio virus is rapid,
acid–resistant, stable, highly tissue specific and consists of a single–stranded, positive RNA. Polio virus is able to reside in the throat or intestinal tract
of humans. Poliomyelitis is a highly contagious infectious disease which has three strains, poliovirus 1 (PV1), PV2 and PV3. Polio virus, although rare
in developed countries, can be found in many under–developed countries due to the uncommonness of vaccinations there. Polio is known as a disease
of development. The oldest known record of polio is in an Egyptian stone engraving of a young priest from 1350...show more content...
Receptor–mediated endocytosis is thought to take the receptor into the cell. Polio virus is tissue tropic, meaning it replicates only in specific tissue
types, generally lymphoid tissue in the pharynx and intestine. After uncoating, polio virus, which is an RNA virus, takes a single RNA molecule in its
protective capsid. This RNA can be converted directly to a protein in the cytoplasm. The virus must then replicate its RNA using viral RNA–directed
RNA polymerase. After replication of its own RNA, the virus must package the new RNA into capsids in order to infect more cells.
Transmission
After replication in the mouth and intestine, polio virus spreads through the body via the blood. Polio virus is contained in the Peyer's patches of the
small intestine. Transmission to the central nervous system and neuronal cell destruction is seen in a small number of infected individuals.
Damage
Polio virus affects humans by a lytic cycle. PV1 which is usually associated with epidemics causes paralysis and consequently the most deaths. PV2
normally causes meningitis and a less severe paralysis. PV3 is usually associated with sporadic cases of polio virus. The majority of polio cases
include only diarrhea symptoms or the individual is completely asymptomatic. Five percent of polio cases show flu–like symptoms of fever, malaise,
headache, nausea, sore throat, upset stomach, and achy muscles. In one percent of
14. Poliomyelitis
POLIO
Poliomyelitis popularly known as polio was first described by Michael Underwood in 1789. It is a highly infectious viral disease which mostly affects
children. The virus is transmitted from person to person via fecal–oral route and less frequent by common vehicle route like contaminated water or
food. Polio is a member of the enteroviruses which are transient inhabitants of the gastrointestinal tracts and stable at acid pH. The incubation period for
poliomyelitis is 6 to 20 days with a range of 3 to 35 days. The preclinical phase of poliomyelitis varies from asymptomatic to presentation of mild
systemic symptoms ranging from pharyngitis or gastroenteritis thus it can mistake at the initial stage as a minor infection. About 95%...show more
content...
Therefore, the suspicion of polio as a differential diagnosis is mostly days after the onset of symptoms. Isolation of the polio virus is principal to
the diagnosis of the disease. The likelihood of polio virus isolation is highest from stool specimen, intermediate from pharyngeal swabs and low
for blood and spinal fluids. Polio virus shedding can be intermediate and does increase the probability of polio virus isolation. At least two stool
specimens and two throat swab should be obtained 24 hours apart from patients as early as it considered as a differential diagnosis. This is ideally
within the first 14 days after the onset of the onset of the disease. It is important to determine whether the polio virus isolated is wild or vaccine
related. Serologic test may be helpful in assisting the diagnosis of paralytic poliomyelitis and acute serum specimen should be obtained as early in the
course of disease as possible, and a convalescent specimen should be obtained at least three weeks later. Cerebral spinal fluid usually contains
increased number of leucocytes and mildly elevated protein. These findings are non–specific and may result in a variety of infections and
non–infectious conditions. Therefore, the best diagnostic test is a isolation of the polio virus from stool specimen (Wallace and Oberste,
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15. Polio Summary
Polio was a deadly disease that struck the United States hard with various epidemic breakouts throughout the country. There are many books written
about the disease and how it was controlled. Polio is a well–researched topic in today's medical world but in this book, Heather Green Wooten, takes it
one step further. She placed the focus of the book in the south, a place where the disease struck almost last yet it claimed many lives. It specifies on
the state of Texas. In addition to that, she combined the disease epidemic with the social and economic development of the state in the twentieth
century. The book follows a well–organized chronological order stating by the early cases of polio and its spread. Then it talks about Franklin D...show
more content...
The purpose of the chapter is to provide the readers with some background information. Along with this, it also shows how panic overtook the
American communities. The uncertainty of what the virus was or where it came from caused a paranoia in many cities. The initial reaction was
to quarantine victims and keep them away from the general public. The spread of the epidemic from northern states to Texas is accredited,
according to Wooten, by the mass immigration into Texas by residents of other states during the oil industry's boom in Texas in the early twentieth
century. This exposed many people to polio as they moved into cities and the coastal area of Texas became more and more urbanized. The high
standards of American hygene made polio a death threat. The body did not have the ability of fighting a small dose of the disease as new born did
when hygene in the country was not so clean. By not being exposed to the virus the body did not produce the adequate antibodies to fight it off.
When it struck at a later age the body was defenseless and so the epidemic started. The result of the urbanization of Texas and the many polio
outbreaks helped the area create many hospitals and lead the fight against polio. The book also highlights the life of Franklin D. Roosevelt, who also
suffered of polio. Wooten describes how the president acquired the disease and
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16. Polio History
Arthur C. Clarke once said, "Any sufficiently advanced technology is indistinguishable from magic." Indeed, this has proven to be true. Technology
has broken down barriers and has led to an easier life, and thus has spread so widely and quickly. Technology has seen incredible growth since ancient
times; from the pyramids to the printing press to robots. The discovery of DNA and the creation of the polio vaccine are both incredible discoveries of
the 1950's that continue to impact the world today.
In the year of 1896, a scientist named Friedrich Meiser discovered DNA. However, the actual role and structure of DNA was still under question until
Erwin Chargaff proved that adenine, thymine, guanine, and cytosine are not equally present in DNA...show more content...
He said that during polio's peak in the 1940's, there were many precautions being taken by families, not allowing kids to go to public places like
the movie theater and avoiding soda cans (Weeks). To help combat polio, The March of Dimes was founded to raise money for people suffering
from polio; they used posters showing pictures of children in crutches and iron lungs to help raise money (Singer 741). The vaccine was a miracle
that came to the American people, and greatly subdued polio cases, as Morris remembers (Morris), and the numbers don't disagree either. In 1945,
the total number of reported polio cases in the United States was 13,624 and it rose to 42, 033 in 1949 ("PHI: Incidence Rates of Poliomyelitis in
US"). In 1955, the year the vaccine was declared effective and put into use, the total cases dropped to 28, 985 then dropped to 8,425 in 1959 ("PHI:
Incidence Rates of Poliomyelitis in US"). The polio vaccine had certainly been influential since it brought down the number of polio cases to zero
by 2008 ("PHI: Incidence Rates of Poliomyelitis in US"). Everyone gets their vaccine today to prevent another outbreak, and this vaccine has spread
abroad to other nations that faced, or are facing a polio crisis. In fact, Nepal was introduced to the IPV about a couple of years ago and Nepal was
declared polio free soon after (Pokharel). If it weren't for the creation of the vaccine, who knows how even more deadly polio would have become
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17. The Global Eradication of Polio Essays
The Global Eradication of Polio
The possibility of the eradication of polio worldwide is an imminent and exciting prospect as the "goal" year quickly approaches. In 1988, the World
Health Assembly, which governs the World Health Organization, set the goal of eliminating polio from the world by the year 2010. Many
organizations have joined the effort along with the World Health Organization: the Center for Disease Control and Prevention, UNICEF, Rotary
International, Global Health Network, the US Agency for International Development, National Immunization Day, and the International Broadcasting
Bureau. Together, these "worldwidepolio partners" have implemented a strategy to completely rid the world of this disease. It is a difficult...show more
content...
The poliovirus enters the body through the mouth, and multiplies in the throat and intestines. It may remain unmanifested for anywhere from four to
thirty–five days. Once the virus is in the intestines it has the potential to spread throughout the body by way of the bloodstream, and infiltrate into the
central nervous system. In the central nervous system, the virus can spread out along the nerve fibers and begin to destroy the nerve cells, or motor
neurons, resulting in limpness in the arms and legs. This is known as acute flaccid paralysis and this symptom of polio (also a symptom of several
other diseases) is used to uncover new cases which may have been misdiagnosed or not diagnosed at all (WHO 1999). This is a necessary procedure
in that it helps to cover all the bases in the pursuit of eradicating poliovirus from the earth.
It is important to note that paralysis does not occur in all polio cases. Acute poliomyelitis manifests itself as a two–phased disease in a small proportion
of its victims. The first phase is minor, a "non–specific febrile illness" (Prevots 1999). All patients with polio experience this phase, and only a small
percentage develops the second phase, "aseptic meningitis and/or paralytic disease" (Prevots 1999). The aseptic meningitis is inflammation, caused by
the virus, of the meninges of the
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