Climate change is increasing the frequency and intensity of extreme weather events like heat waves, droughts, and heavy precipitation. As global temperatures rise, the atmosphere can hold more water vapor, increasing moisture available for storms. Observations show more extreme heat, fewer cold extremes, more intense precipitation events, and longer dry spells. Studies find the 2003 European heat wave and other events were made more likely due to human-caused climate change. Climate models project further increases in heat waves, heavy rain, and other extremes as greenhouse gases continue to rise.
"Climate Change 2007: The Physical Science Basis", assesses the current
scientific knowledge of the natural and human drivers of climate change,
observed changes in climate, the ability of science to attribute changes
to different causes, and projections for future climate change.
The report was produced by some 600 authors from 40 countries. Over 620
expert reviewers and a large number of government reviewers also
participated. Representatives from 113 governments reviewed and revised
the Summary line-by-line during the course of this week before adopting
it and accepting the underlying report.
“Climate Change
2007: The Physical Science Basis”, assesses the current scientific knowledge of
the natural and human drivers of climate change, observed changes in climate,
the ability of science to attribute changes to different causes, and projections
for future climate change.
The report was
produced by some 600 authors from 40 countries. Over 620 expert reviewers and a
large number of government reviewers also participated. Representatives from 113
governments reviewed and revised the Summary line-by-line during the course of
this week before adopting it and accepting the underlying
report.
This is the fifth lesson taught under the course - Climate Change and Global Environment at the Faculty of Social Sciences and Humanities, Rajarata University of Sri Lanka
Presentation given by Chris Swanston to the the Hudson to Housatonic (H2H) Conservation Initiative for the H2H Conservation in a Changing Climate workshop on December 11, 2014.
"Climate Change 2007: The Physical Science Basis", assesses the current
scientific knowledge of the natural and human drivers of climate change,
observed changes in climate, the ability of science to attribute changes
to different causes, and projections for future climate change.
The report was produced by some 600 authors from 40 countries. Over 620
expert reviewers and a large number of government reviewers also
participated. Representatives from 113 governments reviewed and revised
the Summary line-by-line during the course of this week before adopting
it and accepting the underlying report.
“Climate Change
2007: The Physical Science Basis”, assesses the current scientific knowledge of
the natural and human drivers of climate change, observed changes in climate,
the ability of science to attribute changes to different causes, and projections
for future climate change.
The report was
produced by some 600 authors from 40 countries. Over 620 expert reviewers and a
large number of government reviewers also participated. Representatives from 113
governments reviewed and revised the Summary line-by-line during the course of
this week before adopting it and accepting the underlying
report.
This is the fifth lesson taught under the course - Climate Change and Global Environment at the Faculty of Social Sciences and Humanities, Rajarata University of Sri Lanka
Presentation given by Chris Swanston to the the Hudson to Housatonic (H2H) Conservation Initiative for the H2H Conservation in a Changing Climate workshop on December 11, 2014.
The EPA and Met Eireann in association with the National Dialogue on Climate Action hosted this public lecture on 20 November 2019.
After decades of denial, the global community has now accepted the reality of human-induced climate change and the imperative of tackling it. So is the climate science done, and all we need now are technological solutions? This talk will argue that the role for climate science is greater than ever before, as we face the challenges of how to mitigate global warming, how to adapt to a changing climate, and how to make ourselves more resilient to weather and climate hazards.
Dame Julia Slingo served as Chief Scientist of the UK Met Office from
2009 until her retirement in 2016. Through her career, she has worked at the European Centre for Medium-range Weather Forecasts (ECMWF), the US National Center for Atmospheric Research (NCAR) and Reading University. Dame Julia was elected a Fellow of the Royal Society in 2015 and Foreign Member of the US National Academy of Engineering in 2016.
This presentation is linked the the WIll Steger Foundation's Our Changing Climate Curriculum Guide and presents an overview of the basics of climate change.
The EPA and Met Eireann in association with the National Dialogue on Climate Action hosted this public lecture on 20 November 2019.
After decades of denial, the global community has now accepted the reality of human-induced climate change and the imperative of tackling it. So is the climate science done, and all we need now are technological solutions? This talk will argue that the role for climate science is greater than ever before, as we face the challenges of how to mitigate global warming, how to adapt to a changing climate, and how to make ourselves more resilient to weather and climate hazards.
Dame Julia Slingo served as Chief Scientist of the UK Met Office from
2009 until her retirement in 2016. Through her career, she has worked at the European Centre for Medium-range Weather Forecasts (ECMWF), the US National Center for Atmospheric Research (NCAR) and Reading University. Dame Julia was elected a Fellow of the Royal Society in 2015 and Foreign Member of the US National Academy of Engineering in 2016.
This presentation is linked the the WIll Steger Foundation's Our Changing Climate Curriculum Guide and presents an overview of the basics of climate change.
Toxic effects of heavy metals : Lead and Arsenicsanjana502982
Heavy metals are naturally occuring metallic chemical elements that have relatively high density, and are toxic at even low concentrations. All toxic metals are termed as heavy metals irrespective of their atomic mass and density, eg. arsenic, lead, mercury, cadmium, thallium, chromium, etc.
Professional air quality monitoring systems provide immediate, on-site data for analysis, compliance, and decision-making.
Monitor common gases, weather parameters, particulates.
DERIVATION OF MODIFIED BERNOULLI EQUATION WITH VISCOUS EFFECTS AND TERMINAL V...Wasswaderrick3
In this book, we use conservation of energy techniques on a fluid element to derive the Modified Bernoulli equation of flow with viscous or friction effects. We derive the general equation of flow/ velocity and then from this we derive the Pouiselle flow equation, the transition flow equation and the turbulent flow equation. In the situations where there are no viscous effects , the equation reduces to the Bernoulli equation. From experimental results, we are able to include other terms in the Bernoulli equation. We also look at cases where pressure gradients exist. We use the Modified Bernoulli equation to derive equations of flow rate for pipes of different cross sectional areas connected together. We also extend our techniques of energy conservation to a sphere falling in a viscous medium under the effect of gravity. We demonstrate Stokes equation of terminal velocity and turbulent flow equation. We look at a way of calculating the time taken for a body to fall in a viscous medium. We also look at the general equation of terminal velocity.
Observation of Io’s Resurfacing via Plume Deposition Using Ground-based Adapt...Sérgio Sacani
Since volcanic activity was first discovered on Io from Voyager images in 1979, changes
on Io’s surface have been monitored from both spacecraft and ground-based telescopes.
Here, we present the highest spatial resolution images of Io ever obtained from a groundbased telescope. These images, acquired by the SHARK-VIS instrument on the Large
Binocular Telescope, show evidence of a major resurfacing event on Io’s trailing hemisphere. When compared to the most recent spacecraft images, the SHARK-VIS images
show that a plume deposit from a powerful eruption at Pillan Patera has covered part
of the long-lived Pele plume deposit. Although this type of resurfacing event may be common on Io, few have been detected due to the rarity of spacecraft visits and the previously low spatial resolution available from Earth-based telescopes. The SHARK-VIS instrument ushers in a new era of high resolution imaging of Io’s surface using adaptive
optics at visible wavelengths.
Earliest Galaxies in the JADES Origins Field: Luminosity Function and Cosmic ...Sérgio Sacani
We characterize the earliest galaxy population in the JADES Origins Field (JOF), the deepest
imaging field observed with JWST. We make use of the ancillary Hubble optical images (5 filters
spanning 0.4−0.9µm) and novel JWST images with 14 filters spanning 0.8−5µm, including 7 mediumband filters, and reaching total exposure times of up to 46 hours per filter. We combine all our data
at > 2.3µm to construct an ultradeep image, reaching as deep as ≈ 31.4 AB mag in the stack and
30.3-31.0 AB mag (5σ, r = 0.1” circular aperture) in individual filters. We measure photometric
redshifts and use robust selection criteria to identify a sample of eight galaxy candidates at redshifts
z = 11.5 − 15. These objects show compact half-light radii of R1/2 ∼ 50 − 200pc, stellar masses of
M⋆ ∼ 107−108M⊙, and star-formation rates of SFR ∼ 0.1−1 M⊙ yr−1
. Our search finds no candidates
at 15 < z < 20, placing upper limits at these redshifts. We develop a forward modeling approach to
infer the properties of the evolving luminosity function without binning in redshift or luminosity that
marginalizes over the photometric redshift uncertainty of our candidate galaxies and incorporates the
impact of non-detections. We find a z = 12 luminosity function in good agreement with prior results,
and that the luminosity function normalization and UV luminosity density decline by a factor of ∼ 2.5
from z = 12 to z = 14. We discuss the possible implications of our results in the context of theoretical
models for evolution of the dark matter halo mass function.
Richard's aventures in two entangled wonderlandsRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
Seminar of U.V. Spectroscopy by SAMIR PANDASAMIR PANDA
Spectroscopy is a branch of science dealing the study of interaction of electromagnetic radiation with matter.
Ultraviolet-visible spectroscopy refers to absorption spectroscopy or reflect spectroscopy in the UV-VIS spectral region.
Ultraviolet-visible spectroscopy is an analytical method that can measure the amount of light received by the analyte.
Nutraceutical market, scope and growth: Herbal drug technologyLokesh Patil
As consumer awareness of health and wellness rises, the nutraceutical market—which includes goods like functional meals, drinks, and dietary supplements that provide health advantages beyond basic nutrition—is growing significantly. As healthcare expenses rise, the population ages, and people want natural and preventative health solutions more and more, this industry is increasing quickly. Further driving market expansion are product formulation innovations and the use of cutting-edge technology for customized nutrition. With its worldwide reach, the nutraceutical industry is expected to keep growing and provide significant chances for research and investment in a number of categories, including vitamins, minerals, probiotics, and herbal supplements.
Slide 1: Title Slide
Extrachromosomal Inheritance
Slide 2: Introduction to Extrachromosomal Inheritance
Definition: Extrachromosomal inheritance refers to the transmission of genetic material that is not found within the nucleus.
Key Components: Involves genes located in mitochondria, chloroplasts, and plasmids.
Slide 3: Mitochondrial Inheritance
Mitochondria: Organelles responsible for energy production.
Mitochondrial DNA (mtDNA): Circular DNA molecule found in mitochondria.
Inheritance Pattern: Maternally inherited, meaning it is passed from mothers to all their offspring.
Diseases: Examples include Leber’s hereditary optic neuropathy (LHON) and mitochondrial myopathy.
Slide 4: Chloroplast Inheritance
Chloroplasts: Organelles responsible for photosynthesis in plants.
Chloroplast DNA (cpDNA): Circular DNA molecule found in chloroplasts.
Inheritance Pattern: Often maternally inherited in most plants, but can vary in some species.
Examples: Variegation in plants, where leaf color patterns are determined by chloroplast DNA.
Slide 5: Plasmid Inheritance
Plasmids: Small, circular DNA molecules found in bacteria and some eukaryotes.
Features: Can carry antibiotic resistance genes and can be transferred between cells through processes like conjugation.
Significance: Important in biotechnology for gene cloning and genetic engineering.
Slide 6: Mechanisms of Extrachromosomal Inheritance
Non-Mendelian Patterns: Do not follow Mendel’s laws of inheritance.
Cytoplasmic Segregation: During cell division, organelles like mitochondria and chloroplasts are randomly distributed to daughter cells.
Heteroplasmy: Presence of more than one type of organellar genome within a cell, leading to variation in expression.
Slide 7: Examples of Extrachromosomal Inheritance
Four O’clock Plant (Mirabilis jalapa): Shows variegated leaves due to different cpDNA in leaf cells.
Petite Mutants in Yeast: Result from mutations in mitochondrial DNA affecting respiration.
Slide 8: Importance of Extrachromosomal Inheritance
Evolution: Provides insight into the evolution of eukaryotic cells.
Medicine: Understanding mitochondrial inheritance helps in diagnosing and treating mitochondrial diseases.
Agriculture: Chloroplast inheritance can be used in plant breeding and genetic modification.
Slide 9: Recent Research and Advances
Gene Editing: Techniques like CRISPR-Cas9 are being used to edit mitochondrial and chloroplast DNA.
Therapies: Development of mitochondrial replacement therapy (MRT) for preventing mitochondrial diseases.
Slide 10: Conclusion
Summary: Extrachromosomal inheritance involves the transmission of genetic material outside the nucleus and plays a crucial role in genetics, medicine, and biotechnology.
Future Directions: Continued research and technological advancements hold promise for new treatments and applications.
Slide 11: Questions and Discussion
Invite Audience: Open the floor for any questions or further discussion on the topic.
The ability to recreate computational results with minimal effort and actionable metrics provides a solid foundation for scientific research and software development. When people can replicate an analysis at the touch of a button using open-source software, open data, and methods to assess and compare proposals, it significantly eases verification of results, engagement with a diverse range of contributors, and progress. However, we have yet to fully achieve this; there are still many sociotechnical frictions.
Inspired by David Donoho's vision, this talk aims to revisit the three crucial pillars of frictionless reproducibility (data sharing, code sharing, and competitive challenges) with the perspective of deep software variability.
Our observation is that multiple layers — hardware, operating systems, third-party libraries, software versions, input data, compile-time options, and parameters — are subject to variability that exacerbates frictions but is also essential for achieving robust, generalizable results and fostering innovation. I will first review the literature, providing evidence of how the complex variability interactions across these layers affect qualitative and quantitative software properties, thereby complicating the reproduction and replication of scientific studies in various fields.
I will then present some software engineering and AI techniques that can support the strategic exploration of variability spaces. These include the use of abstractions and models (e.g., feature models), sampling strategies (e.g., uniform, random), cost-effective measurements (e.g., incremental build of software configurations), and dimensionality reduction methods (e.g., transfer learning, feature selection, software debloating).
I will finally argue that deep variability is both the problem and solution of frictionless reproducibility, calling the software science community to develop new methods and tools to manage variability and foster reproducibility in software systems.
Exposé invité Journées Nationales du GDR GPL 2024
(May 29th, 2024) Advancements in Intravital Microscopy- Insights for Preclini...Scintica Instrumentation
Intravital microscopy (IVM) is a powerful tool utilized to study cellular behavior over time and space in vivo. Much of our understanding of cell biology has been accomplished using various in vitro and ex vivo methods; however, these studies do not necessarily reflect the natural dynamics of biological processes. Unlike traditional cell culture or fixed tissue imaging, IVM allows for the ultra-fast high-resolution imaging of cellular processes over time and space and were studied in its natural environment. Real-time visualization of biological processes in the context of an intact organism helps maintain physiological relevance and provide insights into the progression of disease, response to treatments or developmental processes.
In this webinar we give an overview of advanced applications of the IVM system in preclinical research. IVIM technology is a provider of all-in-one intravital microscopy systems and solutions optimized for in vivo imaging of live animal models at sub-micron resolution. The system’s unique features and user-friendly software enables researchers to probe fast dynamic biological processes such as immune cell tracking, cell-cell interaction as well as vascularization and tumor metastasis with exceptional detail. This webinar will also give an overview of IVM being utilized in drug development, offering a view into the intricate interaction between drugs/nanoparticles and tissues in vivo and allows for the evaluation of therapeutic intervention in a variety of tissues and organs. This interdisciplinary collaboration continues to drive the advancements of novel therapeutic strategies.
4. Climate change and extreme
weather events
Changes in extremes matter most for society
and the environment
With a warming climate:
More high temperatures, heat waves
Wild fires and other consequences
Fewer cold extremes.
More extremes in hydrological cycle:
Drought, heavy rains, floods
Intense storms
5. A century of weather-related disasters
Rest of World
More
in US
than
any
where
else
6. Ask the right question!
• Is it global warming?
• Is it natural variability?
These are not the right questions: do not have answers.
We can estimate how rare an event was based solely on
observations (requires good long data and assumptions
of stationary climate)
We may be able to state that the odds are remote
that the event could have occurred without
warming (or without natural variability).
Always a combination of both.
9. Issues for extremes
Data are “messy”
Often data are not available with right sampling
Spatial scales vary: tornadoes to droughts
Extremes are inherently rare
Terminology: High impact but not really
extreme?
Model definitions are often different
Model grid box value may not be comparable to
mean of grid box from observations
10. P1: probability of event under current conditions
P0: probability of event with external driver removed
(requires model)
FAR: Fraction of Attributable Risk = 1-P0/P1
Use coupled models to estimate attributable effect
Use statistical methods to estimate FAR (e.g. Stott et al 2004)
Use GCMs to estimate FAR (e.g. Pall et al 2007)
Extend to other regions and variables (e.g. Hoerling et al 2007)
Assumes model depicts real world.
Estimating extremes in data and models
11. Impacts on human
health and
mortality,
economic impacts,
ecosystem and
wildlife impacts
Heat waves and wild fires
13. 10th (left) and 90th (right) percentiles
Frequency of occurrence of cold or warm temperatures for 202 global
stations with at least 80% complete data between 1901 and 2003 for 3
time periods:
1901 to 1950 (black), 1951 to 1978 (blue) and 1979 to 2003 (orange).
1979-2003
1951-1978
1901-1950
Warm nights are increasing; cold nights decreasing
fewer more fewer more
IPCC
14. The most
important spatial
pattern (top) of
the monthly
Palmer Drought
Severity Index
(PDSI) for 1900
to 2002.
The time series
(below) accounts
for most of the
trend in PDSI.
AR4 IPCC
Drought is increasing most places
Mainly decrease in rain
over land in tropics and
subtropics, but enhanced
by increased atmospheric
demand with warming
15. Absence of
warming by day
coincides with
wetter and
cloudier
conditions
Drought
Increases in rainfall and cloud counter warming
Trend in Warm Days 1951-2003
IPCC 2007
17. Extreme Heat Wave
Summer 2003
Europe
30,000 deaths IPCC AR4
Heat waves are increasing: an example
Trend plus variability?
18. IPCC AR4
Summer temperatures in Switzerland from 1864 to 2003. During the extremely hot
summer of 2003, average temperatures exceeded 22°C, as indicated by the red bar
(a vertical line is shown for each year in the 137-year record).
The odds of the 2003 value, given the rest of the record is about 1 in 10 million.
Change in risk of mean European summer
temperatures exceeding 1.6°C above 1961 to
1990 means.
Stott et al. 2004
Presence or
absence of human
influence
Humans have affected temperatures
20. Changing risk of European heat waves
Stott et al 2004
The observed heat wave in Europe in 2003
becomes commonplace by 2020s
21. Photo Dave Mitchell, Courtesy Myles Allen
Flooding and extremes of precipitation
22. Role of character of precipitation:
Daily Precipitation at 2 stations
0
20
40
1 6 11 16 21 26
0
20
40
1 6 11 16 21 26
Frequency 6.7%
Intensity 37.5 mm
Frequency 67%
Intensity 3.75 mm
Monthly
Amount 75 mm
Amount 75 mm
drought wild fires local
wilting plants floods
soil moisture replenished
virtually no runoff
A
B
23. Moderate or heavy precipitation:
• Can not come from local column.
• Can not come from E, unless light precipitation.
• Has to come from transport by storm-scale
circulation into storm.
On average, rain producing systems
(e.g., extratropical cyclones; thunderstorms)
reach out and grab moisture from distance about
3 to 5 times radius of precipitating area.
24. Air holds more water vapor at higher
temperatures
Total water vapor
Observations show that this is happening at
the surface and in lower atmosphere: 0.55C
since 1970 over global oceans and 4% more
water vapor.
This means more moisture
available for storms and an
enhanced greenhouse effect.
A basic physical law tells us that the water
holding capacity of the atmosphere goes up at
about 7% per degree Celsius increase in
temperature. (4% per F)
25. How should precipitation P change
as the climate changes?
With increased GHGs: increased surface heating
evaporation E and P
With increased aerosols, E and P
Net global effect is small and complex
Warming and T means water vapor as observed
Because precipitation comes from storms gathering up
available moisture, rain and snow intensity :
widely observed
But this must reduce lifetime and frequency of storms
Longer dry spells
Trenberth et al 2003
26. How should precipitation P change
as the climate changes?
“The rich get richer and the poor get poorer”. More
water vapor plus moisture transports from divergence
regions (subtropics) to convergence zones. Result:
wet areas get wetter, dry areas drier (Neelin, Chou)
“More bang for the buck”: The moisture and energy
transport is a physical constraint, and with increased
moisture, the winds can be less to achieve the same
transport. Hence the divergent circulation weakens.
(Soden, Held et al)
“Upped ante” precip decreases on edges of
convergence zones as it takes more instability to
trigger convection: more intense rains and upward
motion but broader downward motion. (Neelin, Chou)
27. Precipitation
Observed trends
(%) per decade
for 1951–2003
contribution to
total annual from
very wet days
> 95th %ile.
Alexander et al 2006
IPCC AR4
Heavy precipitation days are increasing even in places
where precipitation is decreasing.
29. PDSI: severe or extreme drought
Change in area of PDSI in drought using detrended temperature
and precipitation:
Red is no trend in precipitation: Would be much more drought!
Blue is no trend in temperature. Modest warming has contributed
Easterling et al 2007
The warmer
conditions
suggest that
drought would
have been
much worse if
it were not
for the much
wetter
conditions.
And it would
have been
much warmer
too!
30. Increases in extremes in U.S.
2 mo dry days: SW Warm season duration
NV, CA
SW
SW US
Up 5.5 d
TX, OK, NM, AZ US
Up 4.3% NW
Per 40 years 1967-2006 Groisman, Knight 08
Heavy rains: top 0.3% 1 mo dry days: East US
up 1.1%
up 27%
31. N. Atlantic
hurricane
record best
after 1944
with aircraft
surveillance.
Global number
and
percentage of
intense
hurricanes
is increasing
North Atlantic hurricanes have increased with SSTs
SST
(1944-2006)
IPCC
Marked increase
after 1994
36. Downscaling of hurricanes
• Emanuel 2008 BAMS
• Knutson et al 2008 Nature Geoscience
Use climate models projections of the
environmental state
– SST
– Vertical temperature structure (stability)
– Wind shear
Hoskins says: "If the large scale is rubbish, then the
detail is rubbish, too."
--New Scientist, 7 May 2008
37. Downscaling of hurricanes
Knutson et al 2008 Nature
Geoscience
Good replication of
number of tropical
storms
But no storms cat 2 or
higher
Why?
cat 1 cat 2 and above
Models fail to replicate
tropical disturbances of
all sorts: convective
parameterization.
Main reason for
reduction in Atlantic is
wind shear: state more
“El Nino-like”
Does not apply elsewhere
38. Some model studies of extremes
• Frosts: Meehl et al 2004
• Heat waves: Meehl and Tebaldi 2004
• 2003 European heat wave: Stott et al 2004
• Precipitation, dry days: Tebaldi et al 2007
• Many indices Frich et al. 2002
defined 10 standard extremes indices derived from
observed data, then from 9 CMIP3 models for AR4
• Precip: Meehl et al 2005
39. Total number of frost days, defined as the annual total
number of days with absolute minimum temperature below 0⁰C
• Intra-annual extreme temperature range, defined as the
difference between the highest temperature of the year and the
lowest
•Growing season length, defined as the length of the period
between the first spell of five consecutive days with mean
temperature above 5⁰C and the last such spell of the year
• Heat wave duration index, defined as the maximum period of at
least 5 consecutive days with maximum temperature higher by at
least 5⁰C than the climatological norm for the same calendar day
• Warm nights, defined as the percentage of times in the year
when minimum temperature is above the 90th percentile of the
climatological distribution for that calendar day
Frich et al 2002 Clim. Res.
Extremes indices for temperature
40. Number of days with precipitation greater than 10mm
Maximum number of consecutive dry days
Maximum 5-day precipitation total
Simple daily intensity index, defined as the annual total
precipitation divided by the number of wet days
Fraction of total precipitation due to events exceeding
the 95th percentile of the climatological distribution
for wet day amounts
Frich et al 2002 Clim. Res.
Extremes indices for precipitation
42. Combined effects of increased precipitation
intensity and more dry days contribute to mean
precipitation changes
43. (Tebaldi , C., J.M. Arblaster, K. Hayhoe, and G.A. Meehl, 2006: Going to the extremes: An
intercomparison of model-simulated historical and future changes in extreme events. Clim.
Change.)