This document summarizes an approach to generate semantic user profiles from informal communication exchanges like emails, chats and meeting records. It extracts keywords, named entities and concepts from the communications to build user profiles and measure similarity between users. The profiles are used for information retrieval, recommender systems and visualizing interaction networks. An experiment on a university mailing list showed profiles based on concepts best correlated with human judgements of user similarity. Future work could involve long-term trials in organizations and linking profiles to external linked data.