European Patient Perspective on Access and Innovation with Multiplex Genomic Testing, presented by Jan Geissler at ASCO 2018 in Chicago, USA, on 3 June 2018
April 18, 2018
Decision aids can be highly-effective tools to promote shared decision making and support patients in becoming engaged participants in their healthcare. Join us for the first-ever convening with leaders behind a Washington experiment in certifying decision aids, as state officials, health systems, and on-the-ground implementation experts share lessons learned and discuss policy recommendations for national or statewide approaches to decision aid certification.
For more information, visit our website at: http://petrieflom.law.harvard.edu/events/details/decision-aids-for-patients-with-serious-illness
April 18, 2018
Decision aids can be highly-effective tools to promote shared decision making and support patients in becoming engaged participants in their healthcare. Join us for the first-ever convening with leaders behind a Washington experiment in certifying decision aids, as state officials, health systems, and on-the-ground implementation experts share lessons learned and discuss policy recommendations for national or statewide approaches to decision aid certification.
For more information, visit our website at: http://petrieflom.law.harvard.edu/events/details/decision-aids-for-patients-with-serious-illness
April 18, 2018
Decision aids can be highly-effective tools to promote shared decision making and support patients in becoming engaged participants in their healthcare. Join us for the first-ever convening with leaders behind a Washington experiment in certifying decision aids, as state officials, health systems, and on-the-ground implementation experts share lessons learned and discuss policy recommendations for national or statewide approaches to decision aid certification.
For more information, visit our website at: http://petrieflom.law.harvard.edu/events/details/decision-aids-for-patients-with-serious-illness
April 18, 2018
Decision aids can be highly-effective tools to promote shared decision making and support patients in becoming engaged participants in their healthcare. Join us for the first-ever convening with leaders behind a Washington experiment in certifying decision aids, as state officials, health systems, and on-the-ground implementation experts share lessons learned and discuss policy recommendations for national or statewide approaches to decision aid certification.
For more information, visit our website at: http://petrieflom.law.harvard.edu/events/details/decision-aids-for-patients-with-serious-illness
Concise explaining of Evidence-Based Medicine and discussing the following: 1-What is Evidence-Based Medicine?
2-Why Evidence-based Medicine?
3-Options for changing clinicians' practice behaviour
4- EBM Process- Five Steps
5-Seven alternatives to evidence-based medicine
a brief overview about how and why to practice evidence based medicine, its clinical application, what it is and what it is not? benefits and challenges
The benefits of patient involvement in research and development (RE:ACT Congr...jangeissler
Presentation of Jan Geissler, Director EUPATI and Co-Founder CML Advocates Network, about the benefits of involving patients in research and development, and about EUPATI. Held at RE:ACT Conress 2016 on Research of Rare and Orphan Diseases, organized by the Blackswan Foundation on 12 March 2016 in Barcelona, Spain
Clinical Questions types .
A Hierarchy of Preprocessed Evidence.
EBM definition and value.
Knowledge and Skills Necessary for Optimal Evidence-Based Practice.
Basic computer and internet knowledge for electronic searching of the literature
Drug development and treatment strategies may go hand in hand.EUPATI
How early in the development of a new medicine should the discussion between researchers and patients occur? Can such early strategic interaction really maximize the value of the outcome? In this EUPATI webinar, a pharmaceutical industry researcher and a patient expert will present two cases describing the research questions, their interaction and the outcome of this early collaboration. Join us in listening and discussing two very interesting experiences of successful patient involvement in the development of new medicines.
Patient Advocates in Cancer Research: European Patients’ Perspective - Jan ...patvocates
Patient Advocates in Cancer Research: European Patients’ Perspective, presented by Jan Geissler (Twitter @jangeissler) at ISOQOL 19th Annual Conference, Budapast, 26 Oct 2012
April 18, 2018
Decision aids can be highly-effective tools to promote shared decision making and support patients in becoming engaged participants in their healthcare. Join us for the first-ever convening with leaders behind a Washington experiment in certifying decision aids, as state officials, health systems, and on-the-ground implementation experts share lessons learned and discuss policy recommendations for national or statewide approaches to decision aid certification.
For more information, visit our website at: http://petrieflom.law.harvard.edu/events/details/decision-aids-for-patients-with-serious-illness
April 18, 2018
Decision aids can be highly-effective tools to promote shared decision making and support patients in becoming engaged participants in their healthcare. Join us for the first-ever convening with leaders behind a Washington experiment in certifying decision aids, as state officials, health systems, and on-the-ground implementation experts share lessons learned and discuss policy recommendations for national or statewide approaches to decision aid certification.
For more information, visit our website at: http://petrieflom.law.harvard.edu/events/details/decision-aids-for-patients-with-serious-illness
Concise explaining of Evidence-Based Medicine and discussing the following: 1-What is Evidence-Based Medicine?
2-Why Evidence-based Medicine?
3-Options for changing clinicians' practice behaviour
4- EBM Process- Five Steps
5-Seven alternatives to evidence-based medicine
a brief overview about how and why to practice evidence based medicine, its clinical application, what it is and what it is not? benefits and challenges
The benefits of patient involvement in research and development (RE:ACT Congr...jangeissler
Presentation of Jan Geissler, Director EUPATI and Co-Founder CML Advocates Network, about the benefits of involving patients in research and development, and about EUPATI. Held at RE:ACT Conress 2016 on Research of Rare and Orphan Diseases, organized by the Blackswan Foundation on 12 March 2016 in Barcelona, Spain
Clinical Questions types .
A Hierarchy of Preprocessed Evidence.
EBM definition and value.
Knowledge and Skills Necessary for Optimal Evidence-Based Practice.
Basic computer and internet knowledge for electronic searching of the literature
Drug development and treatment strategies may go hand in hand.EUPATI
How early in the development of a new medicine should the discussion between researchers and patients occur? Can such early strategic interaction really maximize the value of the outcome? In this EUPATI webinar, a pharmaceutical industry researcher and a patient expert will present two cases describing the research questions, their interaction and the outcome of this early collaboration. Join us in listening and discussing two very interesting experiences of successful patient involvement in the development of new medicines.
Patient Advocates in Cancer Research: European Patients’ Perspective - Jan ...patvocates
Patient Advocates in Cancer Research: European Patients’ Perspective, presented by Jan Geissler (Twitter @jangeissler) at ISOQOL 19th Annual Conference, Budapast, 26 Oct 2012
Angela Coulter: Getting the best value for patientsThe King's Fund
Dr Angela Coulter, Director of Global Initiatives, Foundation for Informed Medical Decision Making, spoke at The King's Fund's 'Reducing unwarranted variations in health care' conference, giving her expert opinion on how to give the best value for patients: with the right intervention, in the right place, at the right time with the right level of involvement.
Access to treatment, care and clinical trials by patients with rare cancers...patvocates
"Access to treatment, care and clinical trials by patients with rare cancers", presented by Jan Geissler (Twitter @jangeissler) at ESMO congress in Vienna, 30 Sept 2012
How evidence affects clinical practice in egyptWafaa Benjamin
Evidence based medicine is the gold standard for clinical care.
It implies the integration of best research evidence with clinical expertise and patient values.
There is still a wide gap between availability of evidence and its incorporation into routine practice in our country.
Barriers to implementation could be personal, social, institutional, financial and legal barriers.
True practice of evidence based care can only occur where evidence based decisions coincide with patients’ beliefs and clinicians’ preferences.
Continuing medical education programs should be set with integrating evidence based medicine teaching and learning within clinical training.
The importance of presence of local national guidelines which need to take into account variation in expertise, resources and patient preferences across our geographical and cultural contexts .
Customisation of a guideline to meet the local needs of a target patient population is critical to successful implementation.
Evidence-Based Practice Guidelines and Shared Decision Making: Conflicting or...Zackary Berger
How can we bridge physician guidelines, based on the best available evidence, and patient preferences? This workshop was given at the Society of General Internal Medicine 2015 Annual Meeting in Toronto, Canada.
Session Coordinator: Zackary Berger, MD, PhD
Additional Faculty: Michael J. Barry, MD, Kathleen Fairfield, MD, Leigh H. Simmons, MD, James Yeh, MD, Daniella A. Zipkin, MD, Dave deBronkart
Emerging Technologies and Tools in Precision Medicine ResearchClinosolIndia
Precision medicine has witnessed significant advancements with the integration of emerging technologies and innovative tools. This abstract explores the current landscape of precision medicine research, focusing on the role of cutting-edge technologies and tools in revolutionizing healthcare approaches.
Personalized Medicine Opportunity Analysis - Team Neuropeptide - Stanford Ven...neuropeptide
Opportunity analysis project report by Team Neuropeptide, Stanford VentureLab class 2012. Our team is exploring business opportunities in the area of overlap of the fields of neurocomputation, genomics, and medicine. We are looking for successful ways to use neuromorphic algorithms for mining genomic databases and create opportunities for modern agile business models in more accessible and personalized healthcare.
The Dawn of Personalized Healthcare A Deep Dive into Genomic Medicine Centers...aidenhitam
Genomic Medicine Centers (GMCs) are revolutionizing healthcare by integrating an individual's genetic makeup into their medical care. These specialized facilities offer genetic testing, counseling, and personalized treatment plans based on a patient's unique DNA.
GMCs function as hubs for clinical care, research, and education. They provide patients with access to advanced genetic testing, helping diagnose conditions, assess disease risks, and inform treatment decisions. GMCs also play a crucial role in advancing research by collecting and analyzing patient data to unlock the secrets of how genes influence health and disease. Additionally, they educate healthcare professionals and the public about genomics and its applications in medicine.
The impact of GMCs is far-reaching. They empower patients with knowledge about their own health, pave the way for personalized medicine with targeted therapies, and contribute to the development of new diagnostic tools and drugs. However, challenges remain, including ethical considerations around privacy and discrimination, ensuring equitable access for all, and navigating the complexities of interpreting genetic data.
Looking ahead, GMCs are poised to shape the future of healthcare. As technology advances, we can expect more comprehensive genetic testing, seamless integration with electronic health records, and the development of even more precise therapies based on individual genetic profiles. Ultimately, GMCs hold immense potential for improving patient care, promoting preventative strategies, and creating a healthier future for all.
Evidence-Based Practices & Nursing
Introduction
Normally, PICOT format is helpful in formulation of questions in an evidenced based clinical practice. PICOT generated questions generally fall under for main categories of clinical practices. These include; therapy, prevention, diagnosis, etiology as well as Prognosis. The essential elements in PICOT questions. The PICOT format is valuable in addressing research questions comprehensively. Five elements are normally addressed including; population, intervention, comparison, outcome and time as well (Riva, Malik, Burnie, Endicott, & Busse, 2012).
Summary of Case Study
The ever increasingly high incidence of breast cancer conditions has posed serious challenges in the nursing profession. Provision of appropriate healthcare to the cancer patients has been lacking leading to adverse effects of the proliferation of cancerous cells which further worsen the conditions of the patients. As primary care, clinicians have the responsibility to stressing providing healthcare services within healthcare facilities as well as monitoring treatment in home based facilities to help manage cancer condition. Most cancer patient need clinicians who practice evidence-based clinical practices (Riva, Malik, Burnie, Endicott, & Busse, 2012).
Research Question
In cancer patients receiving chemotherapy, will they have better white blood cell count monitoring with a follow-up at home versus follow-up at a health care facility during their treatment?
PICOT Format
1) P-Population: Patients aged 18-60 years-old, breast cancer who have not received chemotherapy in the past six months are subjected to the treatment. Patients with other serious health conditions such as heart diseases were excluded in the study. 30 patients, with 15patients stationed at the healthcare facility while the other 15 patients receiving home-based care, are expected to take part in the study.
2) I -Intervention: The patients will receive dosage based on the age, sex and health general body health as well as the stage of cancer cells proliferation in the body. The patients are required take the prescribed drugs at regular intervals. The subjects will be subjected to treatment under the same during the research study.
3) C-Comparison: All the subject regardless of variations in their level of dose requirement will be subjected to the same treatment for the same duration, 3months. Standardized treatment will be given to subjects with no extreme variations in their level of dose requirement and would be used as an active control group. Using this strategy, it will be possible to minimize the non-specific effects due to a group of the patient receiving treatment within the healthcare.
4) O-Outcome: The response in chemotherapy treatments will be check by examining the numbers of defective cancerous cells in the body tissues. The patients will report to the theatre in order to be examined by an oncologist. The results will be recorded i ...
We can aid decision making from the pre-clinical to the clinical setting, supporting line of sight to the clinic, by identifying and translating crucial biomarker approaches into the real world.
Don't just talk about patient centricity - put meaningful patient engagement ...jangeissler
"Don't just talk about patient centricity - put meaningful patient engagement into the design of your cancer research", presented by Jan Geissler at Meet2Win on 7/5/2021
CML: A tiger in the cage? A (European) perspective on CML disease managementjangeissler
CML: A tiger in the cage? A (European) perspective on CML disease management, presented by Jan Geissler, co-founder CML Advocates Network, at the 5th Friends of Max Leadership Summit in (virtual) India on 21 Feb 2021, Session "Beyond Borders"
Sicht der Patienten auf Real World Data, Register und Versorgungsdatenjangeissler
Sicht der Patienten auf Real World Data, Register und Versorgungsdaten. Präsentation von Jan Geissler beim FACHSYMPOSIUM ONKOLOGIE am 28.10.2020 im Rahmen der Sitzung "Daten aus der klinischen Versorgung - was leisten RWD, Register und versorgungsnahe klinische Studien in der Onkologie?"
Überblick der Aktivitäten von Leukämie-Online und CML Advocates Networkjangeissler
Präsentation von Jan Geissler und Cornelia Borowczak über die Aktivitäten von Leukämie-Online und CML Advocates Network, präsentiert beim Leukämie-Online-Patiententreffen am 22/23.9.2019 in Fulda
Umfrage zur Therapiefreien Remission (TFR) der CML-Patientengemeinschaftjangeissler
Präsentation der vorläufigen deutschen Ergebnisse der Umfrage der CML-Patientengemeinschaft zur den Erfahrungen, Ängsten und Erwartungen im Kontext der Therapiefreien Remission (TFR), präsentiert von Jan Geissler am 30.3.2019 beim Jahrestreffen der Deutschen CML-Allianz in Weimar
Bericht LeukaNET / leukaemie-online.de und CML Advocates Networkjangeissler
Bericht über die Aktivitäten von Leukaemie-Online.de / LeukaNET e.V. und CML Advocates Network, präsentiert auf dem Leukämie-Online-Treffen am 23/23. September 2018
How to get the most of the EHA congress as a CML patient advocatejangeissler
The European Hematology Association's (EHA) annual congress will start on 14 June 2018 in Stockholm. The co-founder of the CML Advocates Network and member of the EHA European Affairs Committee, Jan Geissler, on behalf of the EuroBloodNET ePAG, presents this webinar on how to get the most of EHA as a CML patient advocate.
Through the webinar you will be able to know more about topics as:
- Types of sessions at EHA and their relevance for a CML patient advocate
- How to set your priorities attending this huge congress.
- How to find and engage with key opinion leaders at the EHA Posters Sessions.
- More about EHA Abstracts: how to find them and how to read them.
European Cancer Patient Advocacy: Introduction to the community, key stakehol...jangeissler
Overview of the European cancer patient advocacy community, key stakeholder interfaces and key initiatives and projects in evidence-based advocacy and capacity building. Presented by Jan Geissler, Patvocates, at European School of Oncology Masterclass, 23 Feb 2019, Lisbon, Portugal
Häufige Fragen von CML-Patienten und Welt-CML-Tag 2017jangeissler
"Häufige Fragen von CML-Patienten - und was am Welt-CML-Tag 2017 am 22.9.2017 los war", präsentiert von Jan Geissler im Symposium der Deutschen CML-Allianz beim Jahrestreffen der Deutschen Gesellschaft für Hämatologie und Onkologie (DGHO) am 29.9.2017 in Stuttgart
How to get the most of EHA as a patient advocatejangeissler
"How to get the most of EHA as a patient advocate", presented by Jan Geissler at the EHA / EuroBloodNet Capacity Building Meeting for Patient Advocates on 22 June 2017, Madrid
The Networked Patient Group: How technology changes the face of patient advocacyjangeissler
"The Networked Patient Group: How technology changes the face of patient advocacy", presented by Jan Geissler (@jangeissler) at European Patient Innovation Summit on 4 Oct 2016
Tripartite dimension of interaction of patients, regulators and industry (Jan...jangeissler
Tripartite dimension of interaction of patients, regulators and industry, presented by Jan Geissler as a scene-setting presentation at the EUPATI Workshop on the interaction of patients, regulators and industry on 20 July 2016 in Berlin
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
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Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
Acute scrotum is a general term referring to an emergency condition affecting the contents or the wall of the scrotum.
There are a number of conditions that present acutely, predominantly with pain and/or swelling
A careful and detailed history and examination, and in some cases, investigations allow differentiation between these diagnoses. A prompt diagnosis is essential as the patient may require urgent surgical intervention
Testicular torsion refers to twisting of the spermatic cord, causing ischaemia of the testicle.
Testicular torsion results from inadequate fixation of the testis to the tunica vaginalis producing ischemia from reduced arterial inflow and venous outflow obstruction.
The prevalence of testicular torsion in adult patients hospitalized with acute scrotal pain is approximately 25 to 50 percent
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These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
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- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
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Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
European Patient Perspective on Access and Innovation with Multiplex Genomic Testing
1. Jan Geissler
European Patient Perspective
on Access and Innovation
with Multiplex Genomic
Testing
Jan Geissler
Co-Founder Leukemia Patient Advocates Foundation / CML Advocates Network
Member of the ECCO Patient Advisory Committee
Leader of FUTURES Team at European Patients’ Academy (EUPATI)
2. Jan Geissler
Patients have great hopes in genomic testing to
lead us into targeted, personalized medicine
Individual genetic makeup – and that of the tumour – helps to
understand biology of the disease and plan the most effective, targeted
treatments in the individual patient.
• Prevent progression and death through early diagnosis and detection
of relapse
• Avoid exposure to ineffective treatment:
apply only treatments that are likely to work
• Risk stratification: identify high risk patients to avoid jeopardizing
quality of life too early with overtreatment of low risk patients
3. Jan Geissler
Example CML: If personalized medicine holds its
promise, it’s all about access to diagnostics and
treatment
Example Chronic
Myeloid Leukemia:
All CML patients should
have
• access to all five CML
drugs (TKIs) whenever
needed
• regular standardized
PCR
but is this reality?
Not even in the USA.
Years after diagnosis
Overallsurvival
2002-2009
5-year survival 92%
1997-2003
5-year survival 71%
1995-2001
5-year survival 63%
1986-1994
5 year survival 53%
1983-1994
1983-1994 5 year survival 38%
Source: German CML Study Group
NO ACCESS TO CURRENT DIAGNOSTICS AND DRUGS
ACCESS TO DRUGS & DIAGNOSTICS
4. Jan Geissler
More than 200 cancers, skyrocketing drug costs:
Will genomic testing help us be more effective & efficient?
Structure
of DNA
Restriction
enzymes
DNA
sequencing
Recombinant
DNA
Human
insulin
Dolly
the sheep
Human
genome v1milestones
Source: Nature – How to improve R&D productivity: the pharmaceutical industry's grand challenge, Paul et al (2010)
5. Jan Geissler
Is genomic testing the next
step towards personalized
medicine for all,
or are we creating the next
wave of supermodels:
lovely to look at, very costly,
accessible only to a few,
of no real value to many
Courtesy of Richard Sullivan, King‘s College (2018)
Photo 1: unknown male model, Creative Commons Zero License (CC0), source
Photo 2: Photograph by Designecologist, Creative Commons Zero license (CCO), source
6. Jan Geissler
Access issues to testing may increase
inequalities of access to innovative care
What if patients can’t access a potentially effective drug just
because
• patients can’t access the genetic test for the biomarker
because the center’s favorite lab can’t provide it,
because the treating physician can’t deal with genomic testing,
because the patients insurance doesn’t reimburse it?
• patients don’t understand the information they receive,
and then don’t consent to doing the testing?
8. Jan Geissler
It’s not just about genetic testing, but about
research on Big Data – which we support
• Big Data: Increasing availability of heterogeneous large-scale
databases with genomics, proteomics, metabolomics data will
help identify novel patient aggregates and characterize
clinically relevant information
• Patient engagement in Big Data initiatives like IMI2 HARMONY
(e.g. relevant outcomes, de-identification mechanisms)
increase trust and patient participation in precision medicine
• Citizen controlled data collection, storage & sharing may help
further
9. Jan Geissler
Shared decision making in genomic testing
• Increased demand on direct to consumer genomic testing
demonstrates there is unmet need by patients
• With appropriate information and counseling, patients will
deal with probabilistic measure of certainty on diagnosis or
prognosis
• Information should be made available in appropriate time and
in a language that patients understand
• Can this be done in the average 8.1 minutes counseling time?
• Patient organizations can help with patient communication
10. Jan Geissler
Patient-driven biobank PATH: Ensuring future
(genomic) testing on the primary tumour
• More than 10.600 German women
donated their BC tumour tissue and
blood into the PATH biobank
• One aliquot for research, one remains
property of the patient for future
diagnostics
Patients and Methods of the PATH Biobank – A Resource for Breast Cancer Research
Waldmann, Geburtsh Frauenheilk (2014)
11. Jan Geissler
Genetic testing and patient autonomy in
terms of incidental findings
Package Content Opt-in/
Opt-out
Moral
justification
When to offer?
Default package Life-saving data and data of
immediate clinical urgency
Opt-out Beneficence Always
Additional
package #1
Data of potential or moderate
clinical utility
Opt-in Autonomy
(negative account)
Context-specific
Additional
package #2
Data of reproductive
significance
Opt-in Autonomy
(negative account)
Context-specific
Additional
package #3
Data of personal or
recreational significance
Opt-in Autonomy
(negative account)
Context-specific
Bredenoord et al, Hum Mutat, 2011
(negative account = right not to know)
12. Jan Geissler
Physicians need the tools, education, time
and remit for genomic testing
• More Education – Genomic counseling should become part of HCP’s
education, supported by physician guides for clinicians,
and educational tools to support patients
• Decision support tools – Infrastructure for processing and interpreting
genomic data in daily clinical practice should not just be the privilege
of the top-notch centers
• Better regulation – Large heterogeneity in the way European countries
have regulated genetic testing (medical supervision, genetic
counselling and informed consent), incl. direct to consumer testing
Legislation of direct-to-consumer genetic testing in Europe: a fragmented regulatory landscape. Kalokairnou, J Community Genet (2018)
13. Jan Geissler
Conclusion
• Moving from organ-based oncology to biomarker-based personalized
medicine will become the norm
• Patients see great potential in multiplex genomic testing,
IF results translate into clinically relevant actions
• Medical supervision, genetic counselling, informed consent, direct-to-
consumer testing, regulatory heterogeneity are challenges - but they
can be tackled jointly
• Not just supermodels for some - access to genomic testing and to
therapy may become/remain the main barrier to access to effective
innovative treatments
Jan Geissler <jan@patvocates.net>