This document provides an overview and best practices for Node.js APIs and modules. It discusses streams and buffers, using streams efficiently, buffer usage and memory management. It also covers clustering to exploit multiple CPU cores, writing reusable modules, using timers for scheduling, JSON for data interchange, the NPM registry, and writing native addons in C++. Best practices are provided for each topic like avoiding global state in modules and tracking buffer memory usage. The goal is to introduce developers to core Node.js APIs and programming techniques.