Elizabeth Ann Bayley Seton was born into a prominent Episcopalian family in New York but converted to Catholicism after her husband died in Italy. She founded the Sisters of Charity and established Catholic schools and orphanages in Baltimore, Philadelphia, and New York. Throughout her life, she faced hardship including the death of family members, poverty, and illness, but maintained a strong faith in God. She died of tuberculosis in 1821 while serving as Mother Superior of the Sisters of Charity.