This study investigated the effectiveness of different computer-supported cooperative learning strategies (STAD, Jigsaw II, and TAI) on senior secondary students' physics performance in Nigeria. 167 students from 4 classes participated. Students were assigned to learn about equilibrium of forces and simple harmonic motion using either an independent computer-assisted instruction or one of the cooperative strategies supported by a computer program. Pre- and post-tests were used to measure performance. The study found that the cooperative learning strategies enhanced performance more than independent instruction. Academic ability also influenced performance, but gender did not. This provides support for using computer-assisted instruction within cooperative learning settings to improve physics learning.