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ADVENTURES IN EMERGENCY MEDICINE
UROLOGY
Daniel Morrissy DO
TODAY’S TOPICS
• Infection

• Renal/ureteral Calculi
• Urinary Retention
URINARY TRACT INFECTIONS

• Diagnosis and treatment is
dependent on the age, sex
and commorbities of the
patient
SIGNS AND SYMPTOMS OF UTI
• Dysuria

• Urgency
• Frequency
• Polyuria

• Suprapubic tenderness
• Flank Pain
• Fever
DIAGNOSTIC TESTS
• Urine Culture = Gold standard

• Urine Dipstick
• Nitrite –High Specificity, moderate sensitivity (gram
negatives)
• Leukesterase – less specific, moderate sensitivity
• Hematuria – very sensitive, Low specificity
• Urine Microscopy
• Gram stain sensitive above <105 cfu/mL
SUSPECTED LOWER UTI IN NONPREGNANT
FEMALE
• Absence of vaginal itch or discharge

• Multiple symptoms present = treat (nitrofurantoin or TMP-SMX)
• Few symptoms + Dipstick positive = Treat
• Symptoms + negative or equivocal dipstick = Offer empiric
therapy and investigate further if still symptomatic
SUSPECTED UPPER UTI – NONPREGNANT
FEMALE
• Signs of UTI with fever, flank pain, systemic inflammatory
response
• Urine culture recommended
• Quinolones recommended
• Admission for systemic disease/ unwell
PREGNANT WOMEN
• Symptomatic Bacturia

• Treat with appropriate antibiotic
• Urine culture should be sent
• Follow up culture in 7 days after completion should be done

• Asymptomatic Bacturia
• Urine culture to determine treatment – NOT dipstick
• If culture positive confirm with second and treat
CATHETER ASSOCIATED UTI
• Signs of UTI without other identifiable source

• <103 cfu/mL of 1 or more bacterial species in urine specimen
where catheter has been changed in last 48 hrs
• Replace catheter if in place >2 weeks to onset of symptoms
• Obtain culture prior to antibiotics from new catheter or
midstream urine
• Pyuria alone cannot differentiate colonization vs infection
• Absence of pyuria suggests alternative diagnosis

• Empiric use of quinalones then guided by culture
CHILDREN
•

Age - Dramatic decrease in prevalence after 1 year
• 0-2 months
• 2 month – 2 years
• 2-6 years
• >6 years

•

Females greater than males

•

Uncircumcised greater than circumcised

•

Specimens should be straight cath or suprapubic aspiration if unable to control urine or
significant external irritation (urine bags are not recommended, only helpful if cx neg)

•

Culture is gold standard

•

Urinalysis can guide initiation of antibiotics (50,000 CFU/ml)
MALE UTI
•

Differentiate Sexually transmitted disease from UTI

•

Prostatitis

•

Epididimitis

•

Epiditimo-orchitis

•

Orchitis
RENAL CALCULI
RENAL CALCULI
ETIOLOGY OF STONE FORMATION
•

Dependant on type of Stone
• Calcium 75% (oxalate > phosphate)
• Struvite 15% (Urease-producing bacteria – proteus, klebsiella, Pseudomonas,
staph)
• Uric Acid 6% (Low urine pH, Low output, high uric acid level)

•

Combination of high concentrations of stone-forming salts and insufficient inhibitory
proteins
DIFFERENTIAL DIAGNOSIS
DIAGNOSITIC STUDIES
• Urinalysis (check for blood, rule out infection)

• Labs – CBC?, Urea??, Cr???
• Radiographic studies – KUB (60% of stones visible),
Intravenous pyelogram
• Ultrasound - Pregnacy/children
• Non-Enhanced CT Abd/Pelvis
• MRI
TREATMENT
• Pain Control – NSAIDS, Narcotics
• Anti-emetics as needed
• IV Fluids???
• Medical Expulsive Therapy – Calcium Channel Blockers, Steroids, Alphaadrenergic Blockers

• Tamsulosin 0.4mg daily x 4 weeks (44% more likely to pass)
HEY DOC?
• How Long does it take for stones to pass?

• What size stone requires Urology consultation?
• What can the patient do to prevent future stone formation?
INDICATIONS OF ADMISSION/ INTERVENTION
• Obstruction with infection

• Intractable pain with refractory vomiting
• Impending renal failure
• Severe dehydration

• Single kidney or transplant
• Bilateral obstruction
• Urinary Extravasation
ACUTE URINARY RETENTION
ACUTE URINARY RETENTION
• Inability to pass urine voluntarily
• Distending bladder causing extreme discomfort
ETIOLOGY
• Pharmacological

• Neurological
• Infectious/Inflammatory
• Obstruction

What is the most common presentation in the emergency department?
PHARMACOLOGICAL CAUSES
•

Increased sphincter tone or prolonged bladder immotillity
• Antiarrhythmics
• Anticholinergics
• Antidepressants
• Antihistamines
• Antihypertensives

• Antiparkinsonians
• Antipsychotics
• Muscle Relaxants
• Sympathomimetics

• Etc…….
NEUROLOGIC CAUSES
•

Diabetic Cystopathy

•

Upper Motor Neuron Lesions – Multiple Sclerosis, Parkinson’s disease, Trauma, Stroke,
neoplasms

•

Lower motor Neuron Lesions – Spinal cord tumors, epidural abcesses, trauma
INFECTIOUS CAUSES
•

Urethritis, Prostatitis, Severe Vulvovaginitis

•

Genital Herpes – involving the Sacral nerves
OBSTRUCTIVE CAUSES
•

Intrinsic – BPH, bladder stones, blood clots

•

Extrinsic – Masses, cystocele, rectocele
Women

Men

Obstructive – Cystocele, tumor

Obstructive – BPH, Meatal stenosis,
Phimosis/paraphimosis, tumor

Infectious

Infectious

Operative

Operative
LABORATORY TESTING
• Urinalysis – MOST IMPORTANT
• Hematuria
• Infection

• Electrolytes, Urea, Creatinine – Evaluate renal function in setting of prolonged
obstruction

• CBC – Select patients with serious infection, hematologic disorders or hypovolemia
IMAGING STUDIES
•

Bladderscan – bladder volume

• Renal Ultrasound – Hydronephrosis, stone, obstruction
• Bladder ultrasound – Bladder masses,stone, free fluid, volume

Does the degree of hydronephrosis correlate with serum creatinine?
TREATMENT
• Immediate and complete decompression of the bladder through urinary
catheterization
• Complications – Hematuria, hypotension, post-obstructive
diuresis(Which patients are at risk?), infection.

What is the proper technique?
TYPES OF CATHETERS

Foley Cathetyer

Coude Catheter

When do you use each catheter?

Triple lumen catheter
BLADDER IRRIGATION
• What fluid do you use?
RELATIVE CONTRAINDICATIONS TO CATHETER
PLACEMENT
• Pelvic trauma with blood at meatus
• Penile deformity
• Perineal hematoma
• Known impassible catheterization
• History of known recent prostate or bladder neck surgery

When do you call the Urologist?
SUPRAPUBIC CATHETERS INDICATIONS
• Failure of Urethral catheter in Acute Urinary Retention
• Contraindication to urethral catheterization
• Major Urethral Trauma and no Urologist Available

Use ultrasound to help ensure proper placement.
DISPOSITION
•

DISCHARGE if Successful catheterization
• Leave catheter in for BPH (70% recurrence rate)
• Place a leg bag
• Prescribe Alpha Blocker (Tamulosin)

•

ADMIT - If any of the following present:
• Severe infection
• Significant comorbidity
• Impaired Renal function
• Neurological deficits
• Catheter complications
SPECIAL CONSIDERATIONS
• Antibiotics – Only if treating infection
• How long should the catheter stay in? BPH vs precipitated?
• Should you test the foley balloon prior to insertion?
• What should the balloon be filled with? Why?
QUESTIONS?

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ED Urology. Dr Dan Morrissy

  • 1. ADVENTURES IN EMERGENCY MEDICINE UROLOGY Daniel Morrissy DO
  • 2. TODAY’S TOPICS • Infection • Renal/ureteral Calculi • Urinary Retention
  • 3. URINARY TRACT INFECTIONS • Diagnosis and treatment is dependent on the age, sex and commorbities of the patient
  • 4. SIGNS AND SYMPTOMS OF UTI • Dysuria • Urgency • Frequency • Polyuria • Suprapubic tenderness • Flank Pain • Fever
  • 5. DIAGNOSTIC TESTS • Urine Culture = Gold standard • Urine Dipstick • Nitrite –High Specificity, moderate sensitivity (gram negatives) • Leukesterase – less specific, moderate sensitivity • Hematuria – very sensitive, Low specificity • Urine Microscopy • Gram stain sensitive above <105 cfu/mL
  • 6. SUSPECTED LOWER UTI IN NONPREGNANT FEMALE • Absence of vaginal itch or discharge • Multiple symptoms present = treat (nitrofurantoin or TMP-SMX) • Few symptoms + Dipstick positive = Treat • Symptoms + negative or equivocal dipstick = Offer empiric therapy and investigate further if still symptomatic
  • 7. SUSPECTED UPPER UTI – NONPREGNANT FEMALE • Signs of UTI with fever, flank pain, systemic inflammatory response • Urine culture recommended • Quinolones recommended • Admission for systemic disease/ unwell
  • 8. PREGNANT WOMEN • Symptomatic Bacturia • Treat with appropriate antibiotic • Urine culture should be sent • Follow up culture in 7 days after completion should be done • Asymptomatic Bacturia • Urine culture to determine treatment – NOT dipstick • If culture positive confirm with second and treat
  • 9. CATHETER ASSOCIATED UTI • Signs of UTI without other identifiable source • <103 cfu/mL of 1 or more bacterial species in urine specimen where catheter has been changed in last 48 hrs • Replace catheter if in place >2 weeks to onset of symptoms • Obtain culture prior to antibiotics from new catheter or midstream urine • Pyuria alone cannot differentiate colonization vs infection • Absence of pyuria suggests alternative diagnosis • Empiric use of quinalones then guided by culture
  • 10. CHILDREN • Age - Dramatic decrease in prevalence after 1 year • 0-2 months • 2 month – 2 years • 2-6 years • >6 years • Females greater than males • Uncircumcised greater than circumcised • Specimens should be straight cath or suprapubic aspiration if unable to control urine or significant external irritation (urine bags are not recommended, only helpful if cx neg) • Culture is gold standard • Urinalysis can guide initiation of antibiotics (50,000 CFU/ml)
  • 11. MALE UTI • Differentiate Sexually transmitted disease from UTI • Prostatitis • Epididimitis • Epiditimo-orchitis • Orchitis
  • 14. ETIOLOGY OF STONE FORMATION • Dependant on type of Stone • Calcium 75% (oxalate > phosphate) • Struvite 15% (Urease-producing bacteria – proteus, klebsiella, Pseudomonas, staph) • Uric Acid 6% (Low urine pH, Low output, high uric acid level) • Combination of high concentrations of stone-forming salts and insufficient inhibitory proteins
  • 16. DIAGNOSITIC STUDIES • Urinalysis (check for blood, rule out infection) • Labs – CBC?, Urea??, Cr??? • Radiographic studies – KUB (60% of stones visible), Intravenous pyelogram • Ultrasound - Pregnacy/children • Non-Enhanced CT Abd/Pelvis • MRI
  • 17. TREATMENT • Pain Control – NSAIDS, Narcotics • Anti-emetics as needed • IV Fluids??? • Medical Expulsive Therapy – Calcium Channel Blockers, Steroids, Alphaadrenergic Blockers • Tamsulosin 0.4mg daily x 4 weeks (44% more likely to pass)
  • 18. HEY DOC? • How Long does it take for stones to pass? • What size stone requires Urology consultation? • What can the patient do to prevent future stone formation?
  • 19. INDICATIONS OF ADMISSION/ INTERVENTION • Obstruction with infection • Intractable pain with refractory vomiting • Impending renal failure • Severe dehydration • Single kidney or transplant • Bilateral obstruction • Urinary Extravasation
  • 21. ACUTE URINARY RETENTION • Inability to pass urine voluntarily • Distending bladder causing extreme discomfort
  • 22. ETIOLOGY • Pharmacological • Neurological • Infectious/Inflammatory • Obstruction What is the most common presentation in the emergency department?
  • 23. PHARMACOLOGICAL CAUSES • Increased sphincter tone or prolonged bladder immotillity • Antiarrhythmics • Anticholinergics • Antidepressants • Antihistamines • Antihypertensives • Antiparkinsonians • Antipsychotics • Muscle Relaxants • Sympathomimetics • Etc…….
  • 24. NEUROLOGIC CAUSES • Diabetic Cystopathy • Upper Motor Neuron Lesions – Multiple Sclerosis, Parkinson’s disease, Trauma, Stroke, neoplasms • Lower motor Neuron Lesions – Spinal cord tumors, epidural abcesses, trauma
  • 25. INFECTIOUS CAUSES • Urethritis, Prostatitis, Severe Vulvovaginitis • Genital Herpes – involving the Sacral nerves
  • 26. OBSTRUCTIVE CAUSES • Intrinsic – BPH, bladder stones, blood clots • Extrinsic – Masses, cystocele, rectocele
  • 27. Women Men Obstructive – Cystocele, tumor Obstructive – BPH, Meatal stenosis, Phimosis/paraphimosis, tumor Infectious Infectious Operative Operative
  • 28. LABORATORY TESTING • Urinalysis – MOST IMPORTANT • Hematuria • Infection • Electrolytes, Urea, Creatinine – Evaluate renal function in setting of prolonged obstruction • CBC – Select patients with serious infection, hematologic disorders or hypovolemia
  • 29. IMAGING STUDIES • Bladderscan – bladder volume • Renal Ultrasound – Hydronephrosis, stone, obstruction • Bladder ultrasound – Bladder masses,stone, free fluid, volume Does the degree of hydronephrosis correlate with serum creatinine?
  • 30. TREATMENT • Immediate and complete decompression of the bladder through urinary catheterization • Complications – Hematuria, hypotension, post-obstructive diuresis(Which patients are at risk?), infection. What is the proper technique?
  • 31. TYPES OF CATHETERS Foley Cathetyer Coude Catheter When do you use each catheter? Triple lumen catheter
  • 32. BLADDER IRRIGATION • What fluid do you use?
  • 33. RELATIVE CONTRAINDICATIONS TO CATHETER PLACEMENT • Pelvic trauma with blood at meatus • Penile deformity • Perineal hematoma • Known impassible catheterization • History of known recent prostate or bladder neck surgery When do you call the Urologist?
  • 34. SUPRAPUBIC CATHETERS INDICATIONS • Failure of Urethral catheter in Acute Urinary Retention • Contraindication to urethral catheterization • Major Urethral Trauma and no Urologist Available Use ultrasound to help ensure proper placement.
  • 35. DISPOSITION • DISCHARGE if Successful catheterization • Leave catheter in for BPH (70% recurrence rate) • Place a leg bag • Prescribe Alpha Blocker (Tamulosin) • ADMIT - If any of the following present: • Severe infection • Significant comorbidity • Impaired Renal function • Neurological deficits • Catheter complications
  • 36. SPECIAL CONSIDERATIONS • Antibiotics – Only if treating infection • How long should the catheter stay in? BPH vs precipitated? • Should you test the foley balloon prior to insertion? • What should the balloon be filled with? Why?