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Dr. Robert Ferris
(it’s upside down)
 M, 52 y/0, presents with fatigue++
 T2DM
 HTN + CCF
 Smoker + reported hx. of asthma
 No history of MI
 Good adherence to medication, but unsure
what these are:
 “Blood pressure tablet(s)”
 “Inhaler”
U&E → K+ 2.3
↓
HYPOKALAEMIA
 Increased amplitude of P-waves
 PR interval prolongation
 Widespread ST depression andT wave
flattening/inversion
 U-waves
 Long QU interval: QT interval appears
prolonged, due to flattenedT-wave and
presence of U-Wave
 Pt. found to be taking regular furosemide
alongside salbutamol-containing inhaled
medication
 Unclear when furosemide was commenced, and
whether meant to be a regular medication, as
patient also on ramipril
 Unclear how long potassium had been low
 No other complaints, no chest discomfort, no
syncopes/collapse
 Telemetry
 IV K+, slow
 Repeat U&E
 ?repeat echo, if one due
 Take the opportunity for a proper medication
reconciliation
 Inform the patient’s GP once this has been done!!
 HypoK+ often associated with hypoMg2+
 A combination of low K+ and Mg2+ ahave
potentiating destabilising effects on
myocardial cells
 This combination is associated with increased
risk of malignant ventricular arrhythmias
References:
1. Stock photo, HealthMarkets, accessed at https://www.healthmarkets.com/wp-
content/uploads/2016/12/Female-doctor-looking-up-and-thinking.png on 26/10/2021
2. Chest x-ray image, Radiopaedia, accessed at
https://images.radiopaedia.org/images/157210/332aa0c67cb2e035e372c7cb3ceca2.jpg
on 26/10/2021
3. Stock photo, iStockPhoto, accessed at https://media.istockphoto.com/photos/blood-test-
tubes-with-multicolored-lids-isolated-on-white-picture-
id669923240?k=6&m=669923240&s=612x612&w=0&h=IaYmcp9jr58jwZv4VAjC3QH1r4
QZCjrCf8ma7WmMG3U= on 26/10/2021
4. Trepanning, Immediate, accessed at
https://images.immediate.co.uk/production/volatile/sites/7/2015/08/49.-GettyImages-
526352230-371ecdd.jpg?quality=90&resize=620%2C413 on 26/10/2021
5. Hypokalaemia (2021), Life in the Fast Lane, accessed at https://litfl.com/hypokalaemia-
ecg-library/ on 26/10/2021
6. ECG image, accessed at
https://s3.amazonaws.com/static.wd7.us/5/53/SinusRhythmLabels.png on 26/10/2021
7. U Wave (2021), Life in the Fast Lane, accessed at https://litfl.com/u-wave-ecg-library/ on
26/10/2021
8. PR Interval (2021), Life in the Fast Lane, accessed at https://litfl.com/pr-interval-ecg-

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ECG of the Week - Hypokalaemia

  • 3.
  • 4.  M, 52 y/0, presents with fatigue++  T2DM  HTN + CCF  Smoker + reported hx. of asthma  No history of MI  Good adherence to medication, but unsure what these are:  “Blood pressure tablet(s)”  “Inhaler”
  • 5.
  • 6. U&E → K+ 2.3 ↓ HYPOKALAEMIA
  • 7.  Increased amplitude of P-waves  PR interval prolongation  Widespread ST depression andT wave flattening/inversion  U-waves  Long QU interval: QT interval appears prolonged, due to flattenedT-wave and presence of U-Wave
  • 8.
  • 9.
  • 10.
  • 11.
  • 12.  Pt. found to be taking regular furosemide alongside salbutamol-containing inhaled medication  Unclear when furosemide was commenced, and whether meant to be a regular medication, as patient also on ramipril  Unclear how long potassium had been low  No other complaints, no chest discomfort, no syncopes/collapse
  • 13.  Telemetry  IV K+, slow  Repeat U&E  ?repeat echo, if one due  Take the opportunity for a proper medication reconciliation  Inform the patient’s GP once this has been done!!
  • 14.  HypoK+ often associated with hypoMg2+  A combination of low K+ and Mg2+ ahave potentiating destabilising effects on myocardial cells  This combination is associated with increased risk of malignant ventricular arrhythmias
  • 15. References: 1. Stock photo, HealthMarkets, accessed at https://www.healthmarkets.com/wp- content/uploads/2016/12/Female-doctor-looking-up-and-thinking.png on 26/10/2021 2. Chest x-ray image, Radiopaedia, accessed at https://images.radiopaedia.org/images/157210/332aa0c67cb2e035e372c7cb3ceca2.jpg on 26/10/2021 3. Stock photo, iStockPhoto, accessed at https://media.istockphoto.com/photos/blood-test- tubes-with-multicolored-lids-isolated-on-white-picture- id669923240?k=6&m=669923240&s=612x612&w=0&h=IaYmcp9jr58jwZv4VAjC3QH1r4 QZCjrCf8ma7WmMG3U= on 26/10/2021 4. Trepanning, Immediate, accessed at https://images.immediate.co.uk/production/volatile/sites/7/2015/08/49.-GettyImages- 526352230-371ecdd.jpg?quality=90&resize=620%2C413 on 26/10/2021 5. Hypokalaemia (2021), Life in the Fast Lane, accessed at https://litfl.com/hypokalaemia- ecg-library/ on 26/10/2021 6. ECG image, accessed at https://s3.amazonaws.com/static.wd7.us/5/53/SinusRhythmLabels.png on 26/10/2021 7. U Wave (2021), Life in the Fast Lane, accessed at https://litfl.com/u-wave-ecg-library/ on 26/10/2021 8. PR Interval (2021), Life in the Fast Lane, accessed at https://litfl.com/pr-interval-ecg-