Ebola virus is a negative-sense single-stranded RNA virus of the family Filoviridae and genus Ebolavirus. It has five species that cause disease in humans: Zaire, Sudan, Reston, Tai Forest, and Bundibugyo ebolaviruses. The virus enters host cells through macropinocytosis and uses several structural proteins like nucleoprotein, VP30, VP35, VP24, L protein, and VP40 to transcribe and replicate its genome and assemble new virus particles that bud from the cell.