Earl Wilbur Sutherland Jr. was an American pharmacologist and biochemist who won the 1971 Nobel Prize in Physiology or Medicine for his discoveries about hormone mechanisms, especially how epinephrine works through second messengers. He studied at Washburn College and Washington University School of Medicine, and conducted research on how hormones like epinephrine break down glycogen into glucose. After serving as an army physician in WWII, Sutherland held teaching roles in biochemistry and pharmacology at Washington University and Case Western Reserve University. He died in 1974 at age 58 from surgical complications.