The document discusses early detection of viral infections through gene expression analysis. Samples were taken from subjects infected with Lassa virus or Marburg virus over several days. Gene expression levels were measured from the samples. A subset of genes were found to have differential expression 3 days post-exposure, indicating they may serve as early markers of viral infection. Taking multiple samples over time allows analysis of changes in gene expression during the course of infection.
Eccmid 2015 Mykrobe Predictor - A desktop application identifying species and...Phelim Bradley
A desktop application identifying species and antibiotic resistance from S. aureus and M. tuberculosis raw genome sequence data.
The Mykrobe predictor is designed for use by microbiologists and doctors, providing information needed in order to choose the best treatment. It analyses the whole genome of a bacterial sample, all within a couple of minutes, and predicts which drugs the infection is resistant to. No expertise is needed to run or interpret it, and it works on a standard desktop or laptop.
http://www.mykrobe.com/
Khaled El Masry, is an assistant Lecturer of Human Anatomy & Embryology, Mansoura University, Egypt. Great thanks to Prof. Dr Salwa Gawish, professor of Cytology & Histology, Mansoura University, for her great effort in explaining Genetics course.
Eccmid 2015 Mykrobe Predictor - A desktop application identifying species and...Phelim Bradley
A desktop application identifying species and antibiotic resistance from S. aureus and M. tuberculosis raw genome sequence data.
The Mykrobe predictor is designed for use by microbiologists and doctors, providing information needed in order to choose the best treatment. It analyses the whole genome of a bacterial sample, all within a couple of minutes, and predicts which drugs the infection is resistant to. No expertise is needed to run or interpret it, and it works on a standard desktop or laptop.
http://www.mykrobe.com/
Khaled El Masry, is an assistant Lecturer of Human Anatomy & Embryology, Mansoura University, Egypt. Great thanks to Prof. Dr Salwa Gawish, professor of Cytology & Histology, Mansoura University, for her great effort in explaining Genetics course.
A Spanish Daily Routine for People Who Struggle with Daily RoutinesNacho Caballero
Most people would agree that having a daily practice routine helps you learn Spanish faster. However, when we try to stick to an actual routine, we tend to drop it after a few days.
Why does this happen?
In the associated video (http://bit.ly/nachotime_dailyroutine) I share a technique that has given me consistency super powers: planning what you want to do on a piece of paper, doing what you can and tracking what you actually did.
Download the guide: https://itsnachotime.com/dailyroutine/
Creating effective slides without having to become a graphic designerNacho Caballero
This is session 3 of the Awesome Presentations Workshop. You can watch the video for session 2 (developing the story) at https://www.youtube.com/watch?v=jC1glujAhZI
The purpose of a slide is to illustrate an important point in the story. Without a clear story it's impossible to create an effective slide. Once you know what you want to say, notice all the things in your slide and ask why.
Image credit from the Noun Project
Winner by Juan Pablo Bravo
Sadness by Juan Pablo Bravo
Rock Climbing by Paul Phillips
Walking by Dmitriy Lagunov
Man by Matt Brooks
BMX by Marc Serre
How to Build Compelling Research Stories That People Will RememberNacho Caballero
Video: https://www.youtube.com/watch?v=jC1glujAhZI
Session 2 of the Awesome Presentations Workshop
We remember things that surprise us. We remember things that we enjoy. Mostly, we remember things that we understand. Being understood is the main reason to give a presentation, and also its biggest challenge.
Image credits from the Noun Project:
Folder by Sergio Calcara
File by Pham Thi Dieu Linh
Sleep by DonBLC 123
Mountain by Philip Joyce
Beret by Einxel Reyes
Sheriff Hat by Camila Bertoco
Lab meeting presentation about my work doing viral metagenomics in French Guiana
Rat by Francisca Arévalo from The Noun Project
Bat by Adam Heller from The Noun Project
I was invited to give a short presentation about the tools that I use for my research in Cayenne, French Guiana (sickle, velvet, digital normalization (khmer), krona, awk and others).
Bridging data analysis and interactive visualizationNacho Caballero
Clickme is an R package that lets you generate interactive visualizations directly from R. I presented the latest iteration at the 2013 IBSB conference in Kyoto
State of ICS and IoT Cyber Threat Landscape Report 2024 previewPrayukth K V
The IoT and OT threat landscape report has been prepared by the Threat Research Team at Sectrio using data from Sectrio, cyber threat intelligence farming facilities spread across over 85 cities around the world. In addition, Sectrio also runs AI-based advanced threat and payload engagement facilities that serve as sinks to attract and engage sophisticated threat actors, and newer malware including new variants and latent threats that are at an earlier stage of development.
The latest edition of the OT/ICS and IoT security Threat Landscape Report 2024 also covers:
State of global ICS asset and network exposure
Sectoral targets and attacks as well as the cost of ransom
Global APT activity, AI usage, actor and tactic profiles, and implications
Rise in volumes of AI-powered cyberattacks
Major cyber events in 2024
Malware and malicious payload trends
Cyberattack types and targets
Vulnerability exploit attempts on CVEs
Attacks on counties – USA
Expansion of bot farms – how, where, and why
In-depth analysis of the cyber threat landscape across North America, South America, Europe, APAC, and the Middle East
Why are attacks on smart factories rising?
Cyber risk predictions
Axis of attacks – Europe
Systemic attacks in the Middle East
Download the full report from here:
https://sectrio.com/resources/ot-threat-landscape-reports/sectrio-releases-ot-ics-and-iot-security-threat-landscape-report-2024/
A Spanish Daily Routine for People Who Struggle with Daily RoutinesNacho Caballero
Most people would agree that having a daily practice routine helps you learn Spanish faster. However, when we try to stick to an actual routine, we tend to drop it after a few days.
Why does this happen?
In the associated video (http://bit.ly/nachotime_dailyroutine) I share a technique that has given me consistency super powers: planning what you want to do on a piece of paper, doing what you can and tracking what you actually did.
Download the guide: https://itsnachotime.com/dailyroutine/
Creating effective slides without having to become a graphic designerNacho Caballero
This is session 3 of the Awesome Presentations Workshop. You can watch the video for session 2 (developing the story) at https://www.youtube.com/watch?v=jC1glujAhZI
The purpose of a slide is to illustrate an important point in the story. Without a clear story it's impossible to create an effective slide. Once you know what you want to say, notice all the things in your slide and ask why.
Image credit from the Noun Project
Winner by Juan Pablo Bravo
Sadness by Juan Pablo Bravo
Rock Climbing by Paul Phillips
Walking by Dmitriy Lagunov
Man by Matt Brooks
BMX by Marc Serre
How to Build Compelling Research Stories That People Will RememberNacho Caballero
Video: https://www.youtube.com/watch?v=jC1glujAhZI
Session 2 of the Awesome Presentations Workshop
We remember things that surprise us. We remember things that we enjoy. Mostly, we remember things that we understand. Being understood is the main reason to give a presentation, and also its biggest challenge.
Image credits from the Noun Project:
Folder by Sergio Calcara
File by Pham Thi Dieu Linh
Sleep by DonBLC 123
Mountain by Philip Joyce
Beret by Einxel Reyes
Sheriff Hat by Camila Bertoco
Lab meeting presentation about my work doing viral metagenomics in French Guiana
Rat by Francisca Arévalo from The Noun Project
Bat by Adam Heller from The Noun Project
I was invited to give a short presentation about the tools that I use for my research in Cayenne, French Guiana (sickle, velvet, digital normalization (khmer), krona, awk and others).
Bridging data analysis and interactive visualizationNacho Caballero
Clickme is an R package that lets you generate interactive visualizations directly from R. I presented the latest iteration at the 2013 IBSB conference in Kyoto
State of ICS and IoT Cyber Threat Landscape Report 2024 previewPrayukth K V
The IoT and OT threat landscape report has been prepared by the Threat Research Team at Sectrio using data from Sectrio, cyber threat intelligence farming facilities spread across over 85 cities around the world. In addition, Sectrio also runs AI-based advanced threat and payload engagement facilities that serve as sinks to attract and engage sophisticated threat actors, and newer malware including new variants and latent threats that are at an earlier stage of development.
The latest edition of the OT/ICS and IoT security Threat Landscape Report 2024 also covers:
State of global ICS asset and network exposure
Sectoral targets and attacks as well as the cost of ransom
Global APT activity, AI usage, actor and tactic profiles, and implications
Rise in volumes of AI-powered cyberattacks
Major cyber events in 2024
Malware and malicious payload trends
Cyberattack types and targets
Vulnerability exploit attempts on CVEs
Attacks on counties – USA
Expansion of bot farms – how, where, and why
In-depth analysis of the cyber threat landscape across North America, South America, Europe, APAC, and the Middle East
Why are attacks on smart factories rising?
Cyber risk predictions
Axis of attacks – Europe
Systemic attacks in the Middle East
Download the full report from here:
https://sectrio.com/resources/ot-threat-landscape-reports/sectrio-releases-ot-ics-and-iot-security-threat-landscape-report-2024/
Smart TV Buyer Insights Survey 2024 by 91mobiles.pdf91mobiles
91mobiles recently conducted a Smart TV Buyer Insights Survey in which we asked over 3,000 respondents about the TV they own, aspects they look at on a new TV, and their TV buying preferences.
Dev Dives: Train smarter, not harder – active learning and UiPath LLMs for do...UiPathCommunity
💥 Speed, accuracy, and scaling – discover the superpowers of GenAI in action with UiPath Document Understanding and Communications Mining™:
See how to accelerate model training and optimize model performance with active learning
Learn about the latest enhancements to out-of-the-box document processing – with little to no training required
Get an exclusive demo of the new family of UiPath LLMs – GenAI models specialized for processing different types of documents and messages
This is a hands-on session specifically designed for automation developers and AI enthusiasts seeking to enhance their knowledge in leveraging the latest intelligent document processing capabilities offered by UiPath.
Speakers:
👨🏫 Andras Palfi, Senior Product Manager, UiPath
👩🏫 Lenka Dulovicova, Product Program Manager, UiPath
LF Energy Webinar: Electrical Grid Modelling and Simulation Through PowSyBl -...DanBrown980551
Do you want to learn how to model and simulate an electrical network from scratch in under an hour?
Then welcome to this PowSyBl workshop, hosted by Rte, the French Transmission System Operator (TSO)!
During the webinar, you will discover the PowSyBl ecosystem as well as handle and study an electrical network through an interactive Python notebook.
PowSyBl is an open source project hosted by LF Energy, which offers a comprehensive set of features for electrical grid modelling and simulation. Among other advanced features, PowSyBl provides:
- A fully editable and extendable library for grid component modelling;
- Visualization tools to display your network;
- Grid simulation tools, such as power flows, security analyses (with or without remedial actions) and sensitivity analyses;
The framework is mostly written in Java, with a Python binding so that Python developers can access PowSyBl functionalities as well.
What you will learn during the webinar:
- For beginners: discover PowSyBl's functionalities through a quick general presentation and the notebook, without needing any expert coding skills;
- For advanced developers: master the skills to efficiently apply PowSyBl functionalities to your real-world scenarios.
JMeter webinar - integration with InfluxDB and GrafanaRTTS
Watch this recorded webinar about real-time monitoring of application performance. See how to integrate Apache JMeter, the open-source leader in performance testing, with InfluxDB, the open-source time-series database, and Grafana, the open-source analytics and visualization application.
In this webinar, we will review the benefits of leveraging InfluxDB and Grafana when executing load tests and demonstrate how these tools are used to visualize performance metrics.
Length: 30 minutes
Session Overview
-------------------------------------------
During this webinar, we will cover the following topics while demonstrating the integrations of JMeter, InfluxDB and Grafana:
- What out-of-the-box solutions are available for real-time monitoring JMeter tests?
- What are the benefits of integrating InfluxDB and Grafana into the load testing stack?
- Which features are provided by Grafana?
- Demonstration of InfluxDB and Grafana using a practice web application
To view the webinar recording, go to:
https://www.rttsweb.com/jmeter-integration-webinar
UiPath Test Automation using UiPath Test Suite series, part 4DianaGray10
Welcome to UiPath Test Automation using UiPath Test Suite series part 4. In this session, we will cover Test Manager overview along with SAP heatmap.
The UiPath Test Manager overview with SAP heatmap webinar offers a concise yet comprehensive exploration of the role of a Test Manager within SAP environments, coupled with the utilization of heatmaps for effective testing strategies.
Participants will gain insights into the responsibilities, challenges, and best practices associated with test management in SAP projects. Additionally, the webinar delves into the significance of heatmaps as a visual aid for identifying testing priorities, areas of risk, and resource allocation within SAP landscapes. Through this session, attendees can expect to enhance their understanding of test management principles while learning practical approaches to optimize testing processes in SAP environments using heatmap visualization techniques
What will you get from this session?
1. Insights into SAP testing best practices
2. Heatmap utilization for testing
3. Optimization of testing processes
4. Demo
Topics covered:
Execution from the test manager
Orchestrator execution result
Defect reporting
SAP heatmap example with demo
Speaker:
Deepak Rai, Automation Practice Lead, Boundaryless Group and UiPath MVP
The Art of the Pitch: WordPress Relationships and SalesLaura Byrne
Clients don’t know what they don’t know. What web solutions are right for them? How does WordPress come into the picture? How do you make sure you understand scope and timeline? What do you do if sometime changes?
All these questions and more will be explored as we talk about matching clients’ needs with what your agency offers without pulling teeth or pulling your hair out. Practical tips, and strategies for successful relationship building that leads to closing the deal.
Neuro-symbolic is not enough, we need neuro-*semantic*Frank van Harmelen
Neuro-symbolic (NeSy) AI is on the rise. However, simply machine learning on just any symbolic structure is not sufficient to really harvest the gains of NeSy. These will only be gained when the symbolic structures have an actual semantics. I give an operational definition of semantics as “predictable inference”.
All of this illustrated with link prediction over knowledge graphs, but the argument is general.
Key Trends Shaping the Future of Infrastructure.pdfCheryl Hung
Keynote at DIGIT West Expo, Glasgow on 29 May 2024.
Cheryl Hung, ochery.com
Sr Director, Infrastructure Ecosystem, Arm.
The key trends across hardware, cloud and open-source; exploring how these areas are likely to mature and develop over the short and long-term, and then considering how organisations can position themselves to adapt and thrive.
Slack (or Teams) Automation for Bonterra Impact Management (fka Social Soluti...Jeffrey Haguewood
Sidekick Solutions uses Bonterra Impact Management (fka Social Solutions Apricot) and automation solutions to integrate data for business workflows.
We believe integration and automation are essential to user experience and the promise of efficient work through technology. Automation is the critical ingredient to realizing that full vision. We develop integration products and services for Bonterra Case Management software to support the deployment of automations for a variety of use cases.
This video focuses on the notifications, alerts, and approval requests using Slack for Bonterra Impact Management. The solutions covered in this webinar can also be deployed for Microsoft Teams.
Interested in deploying notification automations for Bonterra Impact Management? Contact us at sales@sidekicksolutionsllc.com to discuss next steps.
11. No change
Increase
in expression
Decrease
in expression
Probably
random
Probably significant
30
High
expression
Low
expression
Days post-infection
Significant high magnitude change
Wednesday, May 1, 13
12. No change
Increase
in expression
Decrease
in expression
High
expression
Low
expression
Days post-infection
Probably
random
Probably significant
Significant high magnitude change
30
Wednesday, May 1, 13
13. No change
Increase
in expression
Decrease
in expression
High
expression
Low
expression
Days post-infection
Probably
random
Probably significant
Not significant high magnitude change
30
Wednesday, May 1, 13
14. No change
Increase
in expression
Decrease
in expression
High
expression
Low
expression
Days post-infection
Probably
random
Probably significant
Not significant high magnitude change
30
Wednesday, May 1, 13
15. No change
Increase
in expression
Decrease
in expression
High
expression
Low
expression
Days post-infection
Probably
random
Probably significant
Significant low magnitude change
30
Wednesday, May 1, 13
16. No change
Increase
in expression
Decrease
in expression
High
expression
Low
expression
Days post-infection
Probably
random
Probably significant
Significant low magnitude change
30
Wednesday, May 1, 13
17. A subset of probes is differentially expressed 3 days post-exposure
Wednesday, May 1, 13
18. A subset of probes is differentially expressed 3 days post-exposure
Wednesday, May 1, 13
22. Lassa
Marburg
4
1 2 3 4 5 6 7 8 9 10 11 120
2
1
Days post-exposure
Number of
Samples
1
Test data set
Wednesday, May 1, 13
23. Lassa
Marburg
4
1 2 3 4 5 6 7 8 9 10 11 120
2
1
Days post-exposure
Number of
Samples
1 ✖
Test data set
Wednesday, May 1, 13
24. Aim 1: Early detection of highly pathogenic viral infections
Compare the early transcriptional response of Lassa and Marburg✓
Wednesday, May 1, 13
25. Aim 1: Early detection of highly pathogenic viral infections
Compare the early transcriptional response of Lassa and Marburg✓
Identify a set of candidate biomarker genes✓
Wednesday, May 1, 13
26. Validate the current set of biomarkers using qPCR
Aim 1: Early detection of highly pathogenic viral infections
Compare the early transcriptional response of Lassa and Marburg✓
Identify a set of candidate biomarker genes✓
Wednesday, May 1, 13
27. Validate the current set of biomarkers using qPCR
Compare the differences in using sequencing to measure gene expression
Aim 1: Early detection of highly pathogenic viral infections
Compare the early transcriptional response of Lassa and Marburg✓
Identify a set of candidate biomarker genes✓
Wednesday, May 1, 13
28. Validate the current set of biomarkers using qPCR
Compare the differences in using sequencing to measure gene expression
Incorporate additional viruses to the analysis
Aim 1: Early detection of highly pathogenic viral infections
Compare the early transcriptional response of Lassa and Marburg✓
Identify a set of candidate biomarker genes✓
Wednesday, May 1, 13
29. Aim 2: Visualization of complex biological data
Develop a software tool to easily generate interactive plots✓
Wednesday, May 1, 13
30. Aim 2: Visualization of complex biological data
Develop a software tool to easily generate interactive plots✓
Make generating a dynamic plot as easy as a static one
Wednesday, May 1, 13
31. Aim 2: Visualization of complex biological data
Develop a software tool to easily generate interactive plots✓
Make generating a dynamic plot as easy as a static one
Aim 3: Experimental training
Develop core skills in experimental virology
Wednesday, May 1, 13
32. Aim 2: Visualization of complex biological data
Develop a software tool to easily generate interactive plots✓
Make generating a dynamic plot as easy as a static one
Aim 3: Experimental training
Develop core skills in experimental virology
Design and carry out experiments to determine viral and
host gene function
Wednesday, May 1, 13