DR Sujit 1ST YR MD PHYSIOLOGYmitochondria
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Dr. Sujit Kumar presented on mitochondria structure and function. He discussed the different types of mitochondria within muscle cells, including interfibillar, subsarcolemmal, and pericapillary mitochondria. He then explained how ATP is generated through oxidative phosphorylation using the proton motive force across the inner mitochondrial membrane, driven by the electron transport chain pumping protons from the matrix to the intermembrane space. The proton gradient is then used by ATP synthase to phosphorylate ADP and produce ATP in the matrix.
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Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
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FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
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Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
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Quality of a Good Odorant:
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FCPS Physiology
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MPH (GC University, Faisalabad)
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Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
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Olfactory Genes:
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Total surface area: 5-10 square centimeters.
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Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
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- 1. DEPARTMENTAL PRESENTATION DR. SUJIT KUMAR BSc.(BIOTECH), MD(PHYSIOLOGY) CCH, CGO, SVD (PUNE) SCMT KANPUR PRESENTED BY GUIDED BY DR. RYE GHOSE PhD. SCMT, KANPUR
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- 10. ADP + Pi ATP ATP ATP ADP + Pi ATP ADP + Pi ATP open tight binding loose binding repeat Binding Change Mechanism
- 12. Proton - Motive Force
- 13. ADP + Pi ATP matrix lower [H+ ] _ _ 3 H+ ATP4− ADP3− H2PO4 − H+ higher [H+ ] ADP + Pi cytosol energy requiring reactions ATP4− + +
- 14. THANK YOU