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Gravatar. Jarosław Józef Spychała – doktor nauk chemicznych na Wydziale Chemii UAM w
Poznaniu, ukończył trzyletnie Studia Podoktorskie w Atlancie, członek Nowojorskiej Akademii Nauk
(1987). Autor i współautor licznych artykułów w czasopismach naukowych. Uczestnik krajowych i
międzynarodowych konferencji naukowych. Do jego zainteresowań badawczych należą: działanie
antyrakowe i anty HIV, selektywność, oddziaływania z DNA i RNA, jonowe wiązania wodorowe,
empiryczne reguły, mechanizmy reakcji chemicznych i specjalizuje się w syntezie nowych leków.
Millions of people worldwide depend on the best medicinal drugs. Chemical modification and process
development of new active pharmaceuticals issue an exciting and inspiring challenge to talent
researchers. The topic of research is an interest in understanding biological phenomena at the
molecular and mechanistic level. Without getting into too much detail, the main focus of his interest
was the synthesis of small molecules for treating DNA or RNA associated diseases.
The innovative synthetic organic chemist with the drive and creativity to solve complex scientific
problems and to make a real impact in cancer research set up and developed the future activities
dedicated to imidic acid chemistry including amidines and amides in coordination with the NCI
research group leaders and within the framework of the own anticancer strategy.
Excerpts from the NCBI Biographical Sketch. He put special emphasis on the anticancer cytostatic
and cytotoxic effects. One of the modes of action of anticancer compounds is the targeting of the DNA
of cancer cells (scientifically viable anticancer strategy investigated and verified).
Europass Eportfolio (Work Experience). Independent Studies in Organic Chemistry: Synthetic Studies
in Organic Chemistry, Synthesis of New Polycationic Molecules, Chemical Compounds with Potential
Pharmaceutical Properties as Anticancer Agents. The research works are a valuable contribution to
organic chemistry (peer-reviewed scientific publications including mono-authored articles).
Extracurricular achievements (many brand-new, mainly individual discoveries): original chemical
reactions, reaction mechanisms, spectroscopic results, correlations, reactivity, parallel properties, new
chemical bonds, empirical rules, interaction strength with DNA determined on the basis of anticancer
parameters, identification of selective drugs, and the others are described by author in professional
journals. Scopus Author ID is 7006745874. ORCID Open Researcher and Contributor ID: 0000-0002-
9965-2425. For maximum wow-factor, the resume highlights the scientific output.
Sources: https://europa.eu/europass/eportfolio/api/eprofile/shared-profile/c17532c7-5f5e-42cc-9e45-
06515edc31b7?view=html and https://www.ncbi.nlm.nih.gov/myncbi/jjspychala/cv/490709.
Dr. Spychala on the Road to Stockholm (Pioneering Study)

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Dr. Spychala on the Road to Stockholm (Pioneering Study)

  • 1. Gravatar. Jarosław Józef Spychała – doktor nauk chemicznych na Wydziale Chemii UAM w Poznaniu, ukończył trzyletnie Studia Podoktorskie w Atlancie, członek Nowojorskiej Akademii Nauk (1987). Autor i współautor licznych artykułów w czasopismach naukowych. Uczestnik krajowych i międzynarodowych konferencji naukowych. Do jego zainteresowań badawczych należą: działanie antyrakowe i anty HIV, selektywność, oddziaływania z DNA i RNA, jonowe wiązania wodorowe, empiryczne reguły, mechanizmy reakcji chemicznych i specjalizuje się w syntezie nowych leków. Millions of people worldwide depend on the best medicinal drugs. Chemical modification and process development of new active pharmaceuticals issue an exciting and inspiring challenge to talent researchers. The topic of research is an interest in understanding biological phenomena at the molecular and mechanistic level. Without getting into too much detail, the main focus of his interest was the synthesis of small molecules for treating DNA or RNA associated diseases. The innovative synthetic organic chemist with the drive and creativity to solve complex scientific problems and to make a real impact in cancer research set up and developed the future activities dedicated to imidic acid chemistry including amidines and amides in coordination with the NCI research group leaders and within the framework of the own anticancer strategy. Excerpts from the NCBI Biographical Sketch. He put special emphasis on the anticancer cytostatic and cytotoxic effects. One of the modes of action of anticancer compounds is the targeting of the DNA of cancer cells (scientifically viable anticancer strategy investigated and verified). Europass Eportfolio (Work Experience). Independent Studies in Organic Chemistry: Synthetic Studies in Organic Chemistry, Synthesis of New Polycationic Molecules, Chemical Compounds with Potential Pharmaceutical Properties as Anticancer Agents. The research works are a valuable contribution to organic chemistry (peer-reviewed scientific publications including mono-authored articles). Extracurricular achievements (many brand-new, mainly individual discoveries): original chemical reactions, reaction mechanisms, spectroscopic results, correlations, reactivity, parallel properties, new chemical bonds, empirical rules, interaction strength with DNA determined on the basis of anticancer parameters, identification of selective drugs, and the others are described by author in professional journals. Scopus Author ID is 7006745874. ORCID Open Researcher and Contributor ID: 0000-0002- 9965-2425. For maximum wow-factor, the resume highlights the scientific output. Sources: https://europa.eu/europass/eportfolio/api/eprofile/shared-profile/c17532c7-5f5e-42cc-9e45- 06515edc31b7?view=html and https://www.ncbi.nlm.nih.gov/myncbi/jjspychala/cv/490709.