ANSWER KEYS TO G I SLIDE SEMINAR

1. A....B....C....of Endoscopic Gastric
Biopsies
Dr. S. Rajendiran
Sri Ramachandra University
Porur, Chennai, India
with ANSWERS

3. Case 1
• 60 year male
• Upper GI discomfort for the past 7
months
• Underwent EGD - erosions in the
antrum
• Fundic and antral biopsies taken

8. Corpus Antrum
Ch. Inflammation Severe
Neutrophilic activity Moderate
H. pylori Severe
Intestinal metaplasia
Mild
Atrophy
Case 1
Others:
Nil

9. Case 1 - Diagnosis

10. Case 2
• 38 year male
• Pain in the epigastrium
• History of renal transplant and
immunosuppression
• Underwent EGD - irregular
erythematous areas in the body
• Fundic and antral biopsies taken

11. What do you see?

13. Corpus Antrum
Ch. Inflammation
Mild
Neutrophilic activity
H. pylori
NilIntestinal metaplasia
Atrophy
Case 2
Others:
CMV Inclusions Present

14. Case 2 - Diagnosis

15. Case 3
• 45 year female
• Unexplained megaloblastic anemia for
the past 5 months (Hb. 8 gms%)
• Underwent EGD - Gastric erosions,
more in the body with relative antral
sparing
• Fundic and antral biopsies taken

19. Corpus Antrum
Ch. Inflammation Mild
Nil
Neutrophilic activity
Nil
H. pylori
Intestinal metaplasia Moderate
Atrophy Marked
Case 3
Others:
Endocrine cell
hyperplasia
Pyloric metaplasia

20. Case 3 - Diagnosis

21. Case 4
• 56 year female
• H/O malabsorbtion present 5 months.
Duodenal biopsy showed evidence of
celiac disease
• Now presented with dyspepsia
• Underwent EGD - Irregular nodularity
• Fundic and antral biopsies taken

24. Corpus Antrum
Ch. Inflammation
Nil
Severe
Neutrophilic activity
Nil
H. pylori
Intestinal metaplasia
Atrophy
Case 4
Others:
Increased theliolymphocytes
(40%)

25. Case 4 - Diagnosis

26. Case 5
• 66 year female
• Now presented with heart burn - 4
months
• H/O Rheumatoid Arthritis +
• Underwent EGD - pre-pyloric mucosal
ulcerations
• Fundic and antral biopsies taken

29. Corpus Antrum
Ch. Inflammation
Nil
Neutrophilic activity
H. pylori
Intestinal metaplasia
Atrophy
Case 5
Others:
1. Villiform surface changes
2. Edema of lamina propria
3. Muscularis mucosa Hyperplasia with
ext. in to LP

30. Case 5 - Diagnosis

31. Case 6
65, male, subtotal gastrectomy,
? ca

33. Granulomatous gastritis

34. Case 7
55, male, GE junction polyp ?
ca

35. Gastric fundic gland
polyp

36. Case 8
62, female, multiple gastric
polyps

38. PJ polyp

39. Case 9
50, male, gastric polyp

41. Hyperplastic polyp with xanthoma

42. Case 10
57, female, gastric growth
biopsy

44. Poorly diff. ca. with focal signet cells

46. A....B.....C....of
Gastritis