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Double Trouble
Case 1 ,[object Object],[object Object],[object Object],[object Object]
Case 1
Case 1 ,[object Object],[object Object]
75 YR Man WITH DIPLOPIA ,[object Object],[object Object],[object Object],[object Object]
Hospital Course ,[object Object],[object Object],[object Object],[object Object],[object Object]
PMH ,[object Object],[object Object],[object Object],[object Object],[object Object]
PAST OCULAR HISTORY ,[object Object],[object Object],[object Object]
Medications ,[object Object],[object Object],[object Object]
Examination ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
 
 
 
 
 
 
NEXT STEP(S)?
 
 
78 YEAR OLD WOMAN ,[object Object],[object Object],[object Object]
MEDICAL HISTORY ,[object Object],[object Object],[object Object]
EXAMINATION AS SHOWN MOTILITY 15/15 15/15 COLOR WNL WNL FUNDUS FULL FULL CVF 5 -> 3 7 -> 6 PUPILS 20/40 20/60 VISION OS OD
 
 
 
MRI: T2-WEIGHTED
MRI: T1-WEIGHTED WITH GADOLINIUM
HOSPITAL COURSE ,[object Object],[object Object],[object Object]
 
R L
Aberrant Regeneration of the Third Nerve ,[object Object],[object Object],[object Object],[object Object]
Evaluation of Isolated TNP Complete Partial Pupil involved ? No Ischemic risk factors ? Yes Observe MRI/MRA (or CTA) Yes Pupil involved ? Yes No Re-evaluate after 1 week involved spared Observe if ischemic risk factors, otherwise consider Imaging, LP Modified from clinical pathways in neuro-ophthalmology , AG Lee
PUPIL SPARING REPORTED IN 8-15% OF III-PALSY DUE TO ANEURYSMS PUPIL SPARING CN III PALSY 10 YEARS OLD MRI / MRA 20 YEARS OLD MRI / MRA, ? A-GRAM 40 YEARS OLD MRI / MRA, ? A-GRAM 60 YEARS OLD B/P, FBS, ?ESR, FOLLOW DAILY
Different scenario  ,[object Object],[object Object]
Different scenario  ,[object Object],[object Object],[object Object],[object Object]
Different scenario Pseudo Von-Graffe’s sign Lid retraction in adduction
MRA WILL PICK UP 95% OF ANEURYSMS > 3mm MRA CONVENTIONAL A-GRAM
MRA
CTA or MRA ? 5-6 mm aneurysms can be missed Aneurysm detection Evaluation of Neck vessels Flexibility of display Contrast Patients with implanted metal Scanning time Superior Problematic  Superior Not necessary in 3D TOF and 2D TOF Iodinated contrast Contraindicated Can be used Longer Short MRA CTA
Case ,[object Object],[object Object],[object Object]
Motility
Case ,[object Object],[object Object]
Video Fatigability
Case 23 Orbicularis weakness OD >OS
Always remember ! ,[object Object]
Imaging for isolated Non-traumatic TNP ,[object Object],[object Object],[object Object],[object Object]

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Diplopia Case Workup and Diagnosis in 55 Year Old Diabetic

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  • 23. EXAMINATION AS SHOWN MOTILITY 15/15 15/15 COLOR WNL WNL FUNDUS FULL FULL CVF 5 -> 3 7 -> 6 PUPILS 20/40 20/60 VISION OS OD
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  • 28. MRI: T1-WEIGHTED WITH GADOLINIUM
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  • 31. R L
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  • 33. Evaluation of Isolated TNP Complete Partial Pupil involved ? No Ischemic risk factors ? Yes Observe MRI/MRA (or CTA) Yes Pupil involved ? Yes No Re-evaluate after 1 week involved spared Observe if ischemic risk factors, otherwise consider Imaging, LP Modified from clinical pathways in neuro-ophthalmology , AG Lee
  • 34. PUPIL SPARING REPORTED IN 8-15% OF III-PALSY DUE TO ANEURYSMS PUPIL SPARING CN III PALSY 10 YEARS OLD MRI / MRA 20 YEARS OLD MRI / MRA, ? A-GRAM 40 YEARS OLD MRI / MRA, ? A-GRAM 60 YEARS OLD B/P, FBS, ?ESR, FOLLOW DAILY
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  • 37. Different scenario Pseudo Von-Graffe’s sign Lid retraction in adduction
  • 38. MRA WILL PICK UP 95% OF ANEURYSMS > 3mm MRA CONVENTIONAL A-GRAM
  • 39. MRA
  • 40. CTA or MRA ? 5-6 mm aneurysms can be missed Aneurysm detection Evaluation of Neck vessels Flexibility of display Contrast Patients with implanted metal Scanning time Superior Problematic Superior Not necessary in 3D TOF and 2D TOF Iodinated contrast Contraindicated Can be used Longer Short MRA CTA
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  • 45. Case 23 Orbicularis weakness OD >OS
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