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• If you can’t measure something, you can’t
manage it.
• If you can’t measure something, you can’t
manage it.
• If you can’t manage it, you can’t control it.
• If you can’t measure something, you can’t
manage it.
• If you can’t manage it, you can’t control it.
• If you can’t control it, you can’t improve it.
• If you can’t measure something, you can’t
manage it.
• If you can’t manage it, you can’t control it.
• If you can’t control it, you can’t improve it.
“Measurement is the first step that leads to
control and eventually to improvement”
- H. James Harrington
Dorian Greenow
Advisory Board Member
Disclaimer, Disclosure and Conflict of Interest. Information is not intended to be medical or nutrition advice.
Founder and President of
Keto-Check, Inc,
Keto-Mojo Europe, BV. DBA KETO-MOJO.
Living keto since 2015!
Chairman and Founder of
The Ketogenic Foundation
The Ketogenic Foundation fosters Ketogenic
Education, Medical Research, and
Information Sharing for the benefit of
improving the health of humankind. 501(c)(3)
Public Charity
Value For The Patient
• Instant bio-feedback that the dietary
choices are (or not) working.
Maintaining ketosis compliance
Value For The Patient
• Instant bio-feedback that the dietary
choices are (or not) working.
Maintaining ketosis compliance
• Direct connection between their food
and their blood glucose
Value For The Patient
• Instant bio-feedback that the dietary
choices are (or not) working.
Maintaining ketosis compliance
• Direct connection between their food
and their blood glucose
• Gamification of lifestyle changes
Value For The Patient
• Instant bio-feedback that the dietary
choices are (or not) working.
Maintaining ketosis compliance
• Direct connection between their food
and their blood glucose
• Gamification of lifestyle changes
• Control of Self
Value For The Patient
• Instant bio-feedback that the dietary
choices are (or not) working.
Maintaining ketosis compliance
• Direct connection between their food
and their blood glucose
• Gamification of lifestyle changes
• Control of Self
• Lower Healthcare Costs!
Value For The Practitioner
Safety.
Keto can be “prescription strength” - Do no harm.
Source: Virta Health Trail Outcomes
Value For The Practitioner
• Safety. Keto can be
“prescription strength”
• Outcomes and Results
55%
T2 Diabetes Reversal Rate
91%
Eliminated or Reduced Exogenous Insulin
81%
Decrease In Average Insulin Dosage
67%
Of All Diabetes-Specific Medications Removed
*Results after two years on the Virta Treatment
Value For The Practitioner
• Safety. Keto can be
“prescription strength”
• Outcomes and Results
• Patient compliance /accountability.
Prescribed a Ketogenic Lifestyle
74%
Patient Retention
Antidiabetic / Antihypertensive /
Lipid -Lowering Medications
28.1%
Patient Nonadherence
Source: Virta Health Trail Outcomes
Value For The Practitioner
• Safety. Keto can be
“prescription strength”
• Outcomes and Results
• Patient compliance /accountability.
• Remote Patient Monitoring
Value For The Society
• Lowering the burden of health care costs
Value For The Society
• Lowering the burden of health care costs
• Greater health span and productivity
revenue generation
Diabetes is the
5th
Most common cause of
death in the world
Life expectancy is
reduced, on average, by According to the CDC,
10 79,535
Years in people with Occur each year due
Type 2 diabetes to diabetes
$129k
The yearly value of
quality human life
10 Year Loss Of Life
Value For The Society
Quality of life!
Value For The Society
• Lowering the burden of health care costs
• Greater health span and productivity
revenue generation
• Quality of life
• Prevention / reversal of NCD
NCDs could cost the global economy
$47,000,000,000
By 2030
NCDs are now responsible for
2/3
Of premature deaths around the world
Value For The Society
• Lowering the burden of health care costs
• Greater health span and productivity
revenue generation
• Quality of life
• Prevention / reversal of NCD
• Sequestration of carbon?
For every Kg of beef produced
3.5 kg
Of carbon are sequestered in the
farm’s plants and soil.
What is the right test?
It depends…
Blood Testing
Urine Testing Breath Testing
Types of Ketone Bodies
Easy to teach
Relatively cheap material:
Sodium nitroprusside
Non-invasive
Pain free
Ketone Testing: Urinalysis-Acetoacetate
Obtaining urine
Rapid changes in blood
Not used reliably in clinical trials
Subjective/semi-quantitative
Designed for ketoacidosis >10 mmol/L
PRO’s CON’s
Ketone Testing: Breath-Acetone
One-time up front cost
Non-invasive
Pain free
Accuracy for targeted therapies?
Calibration to known control?
Availability of clinical trials data?
Age & ability of the patient
Consistency of technique
Lifestyle-contaminates
Different response in relation to BHB
PRO’s CON’s
Original Study used Mass Spectrometry Tin dioxide (SnO2)ceramic
Limitation of Metal Oxide Sensors
• Alcohol
• Breath mints
• Chewing gum
• Cough drops
• Throat lozenges
• Tobacco and e-cigarettes
• Lip balm
• Lifestyle-contaminates
• Smoking
• Mint or green tea
• Non-sugar sweeteners (e.g. sorbitol)
• Toothpaste
• Water enhancers (e.g. mio)
• Fermented drinks (e.g. kombucha)
Breath-Acetone: Confounders
Lifestyle factors that could lead to false high readings or sensor failure
wait 60 minutes before testing:
Ketone Testing: Blood-BHB
CON’s
Minimally Invasive
Relative cost per strip (Global)
Painful? Genteel, 33G
Point in time vs CKM’s
PRO’s
Internationally Recognized
Accuracy standardized
ISO 15197:2015 CE & FDA Certification
Real time data points
Peer reviewed clinical trial data
Verification by control
Affordable
Bio-Individuality: How do you account for it?
What you do with the
data matters!
“Continuous remote care, with a
data-driven, proactive outreach
to patients, represents a decisive
step forward in contrast to the
currently available episodic,
reactive, patient-initiated care”
- Sarah Hallberg
This model has shown a retention and engagement
rate of 74% at a 2-year timepoint
Traditional implementation types of ketogenic diet,
a classical ketogenic diet, and a modified Atkins diet
were 42%, 52%, and 34%
Interoperability of EHR systems for
patient care and communication
• Telehealth is an essential tool
during the pandemic
• Telehealth up 64% in 2020
TELEHEALTH
• Increase in telemedicine
applications between hospitals
and clinicians/specialists leading
to greater expertise and support
for patients
Positive metabolic and
behavioral change through
interoperability and
communication in acute
remote care
Thank You
keto-mojo.com
Instagram: @ketomojo #ketomojo #whatsyourmojo
Facebook: keto-Mojo @misterketomojo
dorian@keto-mojo.com
Citations
Slide 14 + 15
Source: Virta Health
Slide 15
Source: https://pubmed.ncbi.nlm.nih.gov/30885952/
Slide 17
Source: The Cost of Diabetes | American Diabetics Association
Slide 18
Stefanos Zenious and his colleagues at Stanford Graduate school of business
Slide 32
Source: 260+ Telehealth Compainies to know | 2020 by Laura Dyrda
Slide 30
Source: Telemedicine via Continuous Remote Care: A Proactive, Patient-Centered Approach to Improve Clinical Outcomes
Source: Efficacy of and Patient Compliance with a Ketogenic Diet in Adults with Intractable Epilepsy: A Meta-Analysis

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Dorian Greenow - The Value of Glucose & Ketone Testing for Patient, Practitioner & Society

  • 1.
  • 2. • If you can’t measure something, you can’t manage it.
  • 3. • If you can’t measure something, you can’t manage it. • If you can’t manage it, you can’t control it.
  • 4. • If you can’t measure something, you can’t manage it. • If you can’t manage it, you can’t control it. • If you can’t control it, you can’t improve it.
  • 5. • If you can’t measure something, you can’t manage it. • If you can’t manage it, you can’t control it. • If you can’t control it, you can’t improve it. “Measurement is the first step that leads to control and eventually to improvement” - H. James Harrington
  • 6. Dorian Greenow Advisory Board Member Disclaimer, Disclosure and Conflict of Interest. Information is not intended to be medical or nutrition advice. Founder and President of Keto-Check, Inc, Keto-Mojo Europe, BV. DBA KETO-MOJO. Living keto since 2015! Chairman and Founder of The Ketogenic Foundation The Ketogenic Foundation fosters Ketogenic Education, Medical Research, and Information Sharing for the benefit of improving the health of humankind. 501(c)(3) Public Charity
  • 7.
  • 8. Value For The Patient • Instant bio-feedback that the dietary choices are (or not) working. Maintaining ketosis compliance
  • 9. Value For The Patient • Instant bio-feedback that the dietary choices are (or not) working. Maintaining ketosis compliance • Direct connection between their food and their blood glucose
  • 10. Value For The Patient • Instant bio-feedback that the dietary choices are (or not) working. Maintaining ketosis compliance • Direct connection between their food and their blood glucose • Gamification of lifestyle changes
  • 11. Value For The Patient • Instant bio-feedback that the dietary choices are (or not) working. Maintaining ketosis compliance • Direct connection between their food and their blood glucose • Gamification of lifestyle changes • Control of Self
  • 12. Value For The Patient • Instant bio-feedback that the dietary choices are (or not) working. Maintaining ketosis compliance • Direct connection between their food and their blood glucose • Gamification of lifestyle changes • Control of Self • Lower Healthcare Costs!
  • 13. Value For The Practitioner Safety. Keto can be “prescription strength” - Do no harm.
  • 14. Source: Virta Health Trail Outcomes Value For The Practitioner • Safety. Keto can be “prescription strength” • Outcomes and Results 55% T2 Diabetes Reversal Rate 91% Eliminated or Reduced Exogenous Insulin 81% Decrease In Average Insulin Dosage 67% Of All Diabetes-Specific Medications Removed *Results after two years on the Virta Treatment
  • 15. Value For The Practitioner • Safety. Keto can be “prescription strength” • Outcomes and Results • Patient compliance /accountability. Prescribed a Ketogenic Lifestyle 74% Patient Retention Antidiabetic / Antihypertensive / Lipid -Lowering Medications 28.1% Patient Nonadherence Source: Virta Health Trail Outcomes
  • 16. Value For The Practitioner • Safety. Keto can be “prescription strength” • Outcomes and Results • Patient compliance /accountability. • Remote Patient Monitoring
  • 17. Value For The Society • Lowering the burden of health care costs
  • 18. Value For The Society • Lowering the burden of health care costs • Greater health span and productivity revenue generation Diabetes is the 5th Most common cause of death in the world Life expectancy is reduced, on average, by According to the CDC, 10 79,535 Years in people with Occur each year due Type 2 diabetes to diabetes $129k The yearly value of quality human life 10 Year Loss Of Life
  • 19. Value For The Society Quality of life!
  • 20. Value For The Society • Lowering the burden of health care costs • Greater health span and productivity revenue generation • Quality of life • Prevention / reversal of NCD NCDs could cost the global economy $47,000,000,000 By 2030 NCDs are now responsible for 2/3 Of premature deaths around the world
  • 21. Value For The Society • Lowering the burden of health care costs • Greater health span and productivity revenue generation • Quality of life • Prevention / reversal of NCD • Sequestration of carbon? For every Kg of beef produced 3.5 kg Of carbon are sequestered in the farm’s plants and soil.
  • 22. What is the right test? It depends… Blood Testing Urine Testing Breath Testing
  • 23. Types of Ketone Bodies
  • 24. Easy to teach Relatively cheap material: Sodium nitroprusside Non-invasive Pain free Ketone Testing: Urinalysis-Acetoacetate Obtaining urine Rapid changes in blood Not used reliably in clinical trials Subjective/semi-quantitative Designed for ketoacidosis >10 mmol/L PRO’s CON’s
  • 25. Ketone Testing: Breath-Acetone One-time up front cost Non-invasive Pain free Accuracy for targeted therapies? Calibration to known control? Availability of clinical trials data? Age & ability of the patient Consistency of technique Lifestyle-contaminates Different response in relation to BHB PRO’s CON’s
  • 26. Original Study used Mass Spectrometry Tin dioxide (SnO2)ceramic Limitation of Metal Oxide Sensors
  • 27. • Alcohol • Breath mints • Chewing gum • Cough drops • Throat lozenges • Tobacco and e-cigarettes • Lip balm • Lifestyle-contaminates • Smoking • Mint or green tea • Non-sugar sweeteners (e.g. sorbitol) • Toothpaste • Water enhancers (e.g. mio) • Fermented drinks (e.g. kombucha) Breath-Acetone: Confounders Lifestyle factors that could lead to false high readings or sensor failure wait 60 minutes before testing:
  • 28. Ketone Testing: Blood-BHB CON’s Minimally Invasive Relative cost per strip (Global) Painful? Genteel, 33G Point in time vs CKM’s PRO’s Internationally Recognized Accuracy standardized ISO 15197:2015 CE & FDA Certification Real time data points Peer reviewed clinical trial data Verification by control Affordable
  • 29. Bio-Individuality: How do you account for it?
  • 30. What you do with the data matters!
  • 31. “Continuous remote care, with a data-driven, proactive outreach to patients, represents a decisive step forward in contrast to the currently available episodic, reactive, patient-initiated care” - Sarah Hallberg This model has shown a retention and engagement rate of 74% at a 2-year timepoint Traditional implementation types of ketogenic diet, a classical ketogenic diet, and a modified Atkins diet were 42%, 52%, and 34%
  • 32. Interoperability of EHR systems for patient care and communication • Telehealth is an essential tool during the pandemic • Telehealth up 64% in 2020 TELEHEALTH • Increase in telemedicine applications between hospitals and clinicians/specialists leading to greater expertise and support for patients
  • 33. Positive metabolic and behavioral change through interoperability and communication in acute remote care
  • 34. Thank You keto-mojo.com Instagram: @ketomojo #ketomojo #whatsyourmojo Facebook: keto-Mojo @misterketomojo dorian@keto-mojo.com
  • 35. Citations Slide 14 + 15 Source: Virta Health Slide 15 Source: https://pubmed.ncbi.nlm.nih.gov/30885952/ Slide 17 Source: The Cost of Diabetes | American Diabetics Association Slide 18 Stefanos Zenious and his colleagues at Stanford Graduate school of business Slide 32 Source: 260+ Telehealth Compainies to know | 2020 by Laura Dyrda Slide 30 Source: Telemedicine via Continuous Remote Care: A Proactive, Patient-Centered Approach to Improve Clinical Outcomes Source: Efficacy of and Patient Compliance with a Ketogenic Diet in Adults with Intractable Epilepsy: A Meta-Analysis