This Presentation Prepared from IDF-DAR,BMJ,ADA & Other guidelines.It will cover to solve problems faced by the physicians during management of DM in the Holy Month of Ramadan specially monitoring of blood glucose,Drug doses,dietary and exercise advice etc.
Anti-Obesity Pharmacotherapy: Where are we now? Where are we going?InsideScientific
Obesity is a treatable chronic disease. With nearly 2 billion individuals worldwide classified as being overweight and 650 million as having obesity, it is critical to optimize implementation of existing treatment interventions and develop novel therapies to mitigate the obesity pandemic. Anti-obesity medications are one of the essential tools in our medical toolbox to help patients achieve their health and weight goals.
In this webinar, Dr. Jastreboff discusses current use of anti-obesity pharmacotherapy, mechanisms involved, and agents in various stages of development with considerations for next steps. The presentation aims to inspire development of innovative therapeutics while optimizing use of existing agents to address the urgent need to effectively and sustainably treat millions of individuals with obesity around the world.
Key Topics Include:
- Understand the role of anti-obesity pharmacotherapy in the treatment of obesity
- Describe current anti-obesity pharmacotherapy
- Discuss anti-obesity medications under development
Anti-Obesity Pharmacotherapy: Where are we now? Where are we going?InsideScientific
Obesity is a treatable chronic disease. With nearly 2 billion individuals worldwide classified as being overweight and 650 million as having obesity, it is critical to optimize implementation of existing treatment interventions and develop novel therapies to mitigate the obesity pandemic. Anti-obesity medications are one of the essential tools in our medical toolbox to help patients achieve their health and weight goals.
In this webinar, Dr. Jastreboff discusses current use of anti-obesity pharmacotherapy, mechanisms involved, and agents in various stages of development with considerations for next steps. The presentation aims to inspire development of innovative therapeutics while optimizing use of existing agents to address the urgent need to effectively and sustainably treat millions of individuals with obesity around the world.
Key Topics Include:
- Understand the role of anti-obesity pharmacotherapy in the treatment of obesity
- Describe current anti-obesity pharmacotherapy
- Discuss anti-obesity medications under development
Diabetes and Ramadhan power point slides
talking about diabetes management during the month of ramadhan for patients and health provider. how to get well controlled blood glucose during fasting in ramadhan month without hypoglicemia
In this slide set we present recommendations on the management of Diabetes during the period of Ramadan. Preparations prior to fasting, management during the period and adjustments to be made.
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
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TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
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To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
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Acute scrotum is a general term referring to an emergency condition affecting the contents or the wall of the scrotum.
There are a number of conditions that present acutely, predominantly with pain and/or swelling
A careful and detailed history and examination, and in some cases, investigations allow differentiation between these diagnoses. A prompt diagnosis is essential as the patient may require urgent surgical intervention
Testicular torsion refers to twisting of the spermatic cord, causing ischaemia of the testicle.
Testicular torsion results from inadequate fixation of the testis to the tunica vaginalis producing ischemia from reduced arterial inflow and venous outflow obstruction.
The prevalence of testicular torsion in adult patients hospitalized with acute scrotal pain is approximately 25 to 50 percent
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
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Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
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3. Management of diabetic patients
during the holy month of Ramadan
Dr. Md. Rafiqul Islam
Registrar(Medicine)
M Abdur Rahim Medical College
Hospital
4. Fasting in Ramadan is one of the five pillars
of Islam, therefore, Muslim patients insist on
fasting
Globally more than 50 million Muslim with
diabetes observe fasting in Ramadan
Therefore, managing diabetic patients
observe fasting is a challenge for the clinicians
INTRODUCTION
5. What happens in Ramadan?
Eating habit changes in many ways
- Meal time
- Pattern of meal
- Calorie intake
Increased post-prandial physical
activity during the night associated
with Tarawih
01. Can Fam Physician 2014;60:508-10
12. What are the challenges for
a Clinician during Ramadan
Check eligibility of patient to observe
fasting
Managing risks associated with fasting
Blood glucose monitoring while
fasting
Adjustment of diet, exercise & drugs
22. Recommendations to
avoid hypoglycemia
To take Suhur close to Suhur time
Change the schedule and composition of
meals
Reduce physical activity during day time;
physical exercise can be performed about
one hour after Iftar
02. Clinical Diabetes ( Middle East Edition)- Volume 3, Number 3, 2004
23. General advices
to minimize risks
Consultation with a doctor much before
Ramadan
Practice fasting in the month of Shaban
Switch to long acting drug (preferably once
daily)
Care must be individualized: management
plan will differ for each specific patient
02. Clinical Diabetes ( Middle East Edition)- Volume 3, Number 3, 2004
26. Impact of Education & Counseling
Objective:
The aim of study was to
determine the impact of
Ramadan-focused education on
weight & hypoglycemic
episodes during Ramadan in a
Type 2 diabetic Muslim
population taking oral glucose
lowering agents.04. Diabet. Med. 27, 327–331 (2010)
30. Blood glucose monitoring in Ramadan as per Islam
Both National & International Scholars of Islam
permit blood glucose monitoring while fasting!!
05. A Physician's Guide to Manage Diabetes Mellitus in Ramadan
33. Diet in Ramadan
Drink more water to avoid dehydration
Avoid sugar (sweetener can be used)
Avoid foods rich in fat
Avoid heavy Iftar & light Suhur
Keep same calorie as before Ramadan
Take complex carbohydrate at Suhur
Take Suhur as late as possible
02. Clinical Diabetes ( Middle East Edition)- Volume 3, Number 3, 2004
36. Exercise in Ramadan
Physical activity should be
reduced during day time
Exercise can be performed for an
hour after Iftar
However, increased prayer during
Tarawih should be taken into
account
03. Diabetes Care. 2010 Aug; 33(8): 1895–1902.
37. “And do not kill yourselves [or one another].
Indeed, Allah is to you ever Merciful.”
[An-‐-Nissa: 29]
“and make not your own hands
contribute to (your) destruction”
[Al Baqara: 195].
When To Break Fast
40. Full morning dose at Iftar and half of the
usual evening dose at Suhur
Sulfonylureas twice daily
e.g., gliclazide 80 mg
Patients on oral hypoglycemic agents
No change is needed (modify time and
intensity of exercise), ensure adequate
fluid intake
Patients on diet and exercise
control
During RamadanBefore Ramadan
Same dose should be taken at Iftar
Sulfonylureas once daily
e.g., gliclazide MR
(research brand- DIAMICRON
MR60)
Metformin, 1,000 mg at Iftar, 500 mg at
Suhur
Biguanide,
e.g., Metformin 500 mg thrice daily
Adjustment of Drug/Treatments
03. Diabetes Care. 2010 Aug; 33(8): 1895–1902.
41. As usual at nightGlinide
As usual at nightDPP-4 inhibitor
During RamadanBefore Ramadan
As usual at nightSGLT-2 inhibitor
Adjustment of Drug/Treatments
03. Diabetes Care. 2010 Aug; 33(8): 1895–1902.
42. Insulin therapy
Long- or intermediate-acting basal insulin:
OD –Take at iftar,Reduce dose by 15–30%
BID –Take usual morning dose at iftar,Reduce evening dose
by 50% and take at suhoor
Rapid- or short-acng prandial/bolus insulin:
Take normal dose at iftar,Omit lunch-time dose.
Reduce suhoor dose by 25–50%
Premixed insulin:
OD – Take normal dose at iftar
BID – Take usual morning dose at iftar.Reduce evening dose
by 25–50% and take at suhoor
TID – Omit afternoon dose. Adjust iftar and suhoor doses
43. Dose titraon should be performed every three
days and dose adjustments made according to
BG levels
44. Post-Ramadan
follow-up
• In Eid ul-Fitr, patients with diabetes should be
made aware of overindulgence during this time
• A post-Ramadan follow-up advisable to
discuss medication and regimen readjustments
• It should be stressed that a safe fast one year
does not automatically make them low risk for
the next year
46. Uncomplicated type 2 diabetic patient can fast
in
Ramadan
Pre-Ramadan education is important to
minimize risks
Islam allows blood glucose monitoring while