Eyelid diseases encompass a range of conditions affecting the delicate tissues surrounding the eye. From common issues like blepharitis to more severe conditions like eyelid tumors, these ailments can impact vision and overall eye health. Understanding their causes, symptoms, and treatments is crucial for proper management and prevention.
The eyelids are mobile tissue curtains placed in front of the eyeballs. These act as shutters protecting the eyes from injuries and excessive light. These also perform an important function of spreading the tear film over the cornea and conjunctiva and also help in drainage of tears by lacrimal pump system.
The eyelids are mobile tissue curtains placed in front of the eyeballs. These act as shutters protecting the eyes from injuries and excessive light. These also perform an important function of spreading the tear film over the cornea and conjunctiva and also help in drainage of tears by lacrimal pump system.
this document is designed and serving to successfully help students, teachers or ophthalmic clinicians to deliver a sustained and effective management of conjuctiva disorders
OCULAR TOXOPLASMOSIS the blinding disease and is classified among the torch i...BARNABASMUGABI
the disease spreads from the cats and causes retinochoroiditis and its a blinding disease aswell.its managed with spiromyscin,folinic acid and incase of retinal detachment,vitrectomy is done
this document is designed and serving to successfully help students, teachers or ophthalmic clinicians to deliver a sustained and effective management of conjuctiva disorders
OCULAR TOXOPLASMOSIS the blinding disease and is classified among the torch i...BARNABASMUGABI
the disease spreads from the cats and causes retinochoroiditis and its a blinding disease aswell.its managed with spiromyscin,folinic acid and incase of retinal detachment,vitrectomy is done
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
TEST BANK For Williams' Essentials of Nutrition and Diet Therapy, 13th Editio...kevinkariuki227
TEST BANK For Williams' Essentials of Nutrition and Diet Therapy, 13th Edition Schlenker & Gilbert, Verified Chapters 1 - 25, Complete Newest Version.pdf
TEST BANK For Williams' Essentials of Nutrition and Diet Therapy, 13th Edition Schlenker & Gilbert, Verified Chapters 1 - 25, Complete Newest Version.pdf
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Mastering Wealth: A Path to Financial FreedomFatimaMary4
### Understanding Wealth: A Comprehensive Guide
Wealth is a multifaceted concept that extends beyond mere financial assets. It encompasses a range of elements including money, investments, property, and other valuable resources. However, true wealth also includes non-material aspects such as health, relationships, and personal fulfillment. This guide delves into the various dimensions of wealth, exploring how it can be created, sustained, and enjoyed.
#### Defining Wealth
Traditionally, wealth is defined as the abundance of valuable resources or material possessions. It includes financial assets like cash, savings, stocks, bonds, and real estate. However, a broader understanding of wealth considers factors such as personal well-being, emotional health, social connections, and intellectual growth. This holistic view recognizes that true wealth is not solely about accumulating money but also about enhancing one's quality of life.
#### The Importance of Financial Wealth
Financial wealth remains a critical component of overall wealth. It provides security, freedom, and the ability to pursue opportunities. Key elements of financial wealth include:
1. **Savings**: Money set aside for future use. It is crucial for emergencies, large purchases, and financial goals.
2. **Investments**: Assets purchased with the expectation that they will generate income or appreciate over time. Common investments include stocks, bonds, mutual funds, real estate, and businesses.
3. **Income**: Regular earnings from work, investments, or other sources. Consistent income is essential for maintaining and growing wealth.
4. **Debt Management**: Effectively managing debt ensures that it does not erode financial wealth. This includes paying off high-interest debt and using credit wisely.
#### Creating Wealth
Creating wealth involves generating and accumulating financial and non-financial resources. The process can be broken down into several key strategies:
1. Education and Skill Development: Investing in education and skills enhances earning potential. Higher education, professional certifications, and continuous learning can lead to better job opportunities and higher salaries.
2. Entrepreneurship: Starting and running a successful business can be a significant source of wealth. Entrepreneurship requires innovation, risk-taking, and effective management.
3. Investing: Making smart investments is essential for wealth creation. This involves understanding different types of investments, assessing risks, and making informed decisions. Diversifying investments can reduce risk and increase potential returns.
4. Saving and Budgeting: Effective saving and budgeting help accumulate wealth over time. Setting financial goals, creating a budget, and sticking to it are foundational steps in wealth creation.
5. Real Estate: Investing in property can provide rental income and capital appreciation. Real estate is a tangible asset that can hedge against inflation
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
TEST BANK For Advanced Practice Nursing in the Care of Older Adults, 2nd Edit...kevinkariuki227
TEST BANK For Advanced Practice Nursing in the Care of Older Adults, 2nd Edition by Laurie Kennedy-Malone, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK For Advanced Practice Nursing in the Care of Older Adults, 2nd Edition by Laurie Kennedy-Malone, Verified Chapters 1 - 19, Complete Newest Version.pdf
2. Congenital lid condition
1.Epicanthus:-
Most common congenital lid condition.
Unilateral or bilateral.
Epicanthus is a condition in which a fold of
skin stretches from the upper to the lower
eyelid, partially covering the inner canthus.
3. 2.Telecanthus:-
Telecanthus is an increased distance between
the inner corners of your eyelids (medial
canthi).
• It’s usually a symptom of a genetic disorder.
Telecanthus often occurs with other eye
issues that may affect eyesight.
• Surgical correction is the main treatment for
telecanthus by plastic surgery.
4. 3.Lid coloboma:-
• Eyelid coloboma is a rare congenital
condition where there is an absence of the
development of eyelid tissue.
• Unilateral or bilateral and upper or lower
Eyelid
• Treatment: Urgent plastic repair at a
very early age to prevent exposure
keratitis and corneal ulcer.
5. 4.Districhiasis:-
Distichiasis is a congenital or acquired
condition where eyelashes arise from the
meibomian glands on the posterior
lamella of the eyelid margin.
• Eyelashes may irritate cause to corneal
epithelial defects.
• May be also seen in Stevens Johnson’s
syndrome.
6. 5.Blepharophimosis:-
Blepharophimosis syndrome is a genetic
disorder that causes problems with how
eyelids develop.
If have this syndrome, have narrow eye
openings, droopy eyelids and folds of skin
on the inner part of eyes going from the
bottom to the upper corner.
8. 2.Eyelash ptosis:-
• Downward drooping of upper lid eyelashes .
• Congenital or may be seen after prolong use
of latanoprost eye drop .
• It does not require any treatmen
10. 5.Madarosis:-
• It is loss of the eyelashes
partial or complete.
Causes:-
1. Chronic Blepharitis
2. Burns
3. Post herpes zoster
4. Leprocy
11. 6.Brittle Eyelash:-
•It is rare and bilateral
condition.
•Eyelashes break with
simple rubbing or with
slightest manipulation.
12. 7.Matting of the lashes:-
•Few eyelashes are stuck together
Mostly seen in upper eyelids.
Causes:
– Acute conjunctivitis .
– Blepharitis .
– Bacterial corneal ulcer .
or panophthalmitis .
– Use of eye ointment.
13. 8.Trichomegaly:-
•Excessively long and dense
luxuriant
eyelashes.
• May be associated with newer
antiglaucoma medication, like
Brimatoprost.
• No treatment is required.
14. Entropion
•Inward turning of the eyelids towards the
globe.
•Is is most common in lower lid.
•It is unilateral or bilateral.
•Very rare upper lid and both eyes.
15. Ectropion
•Outward turning of the eyelid away
from the globe.
• Age related condition which affect
the lower lid.
• It is unilateral or bilateral ,most
common in lower lid.
16. INFLAMATION OF THE LIDS
1. Angular Blepharoconjunctivitis :-
Anguler Blepharoconjunctivitis involving the
lateral canthal angle of the eye (the lateral aspect
of where the eyelids meet closest to the temples).
Redness, skin scaling, and irritation will be present
in the canthus area of the eye.
Blepharoconjunctivitis is the combining of a
severe case of blepharitis and conjunctivitis.
Blepharitis is an irritation and inflammation of the
eyelids. Conjunctivitis is an irritation and
inflammation of the conjunctiva.
17. •It is unilateral or bilateral conditions.
• Cause by sensitivity to topical
medication, hair dyes, cosmetics and
spectacles
• Symptoms – Redness, rashes ,
swelling, itching, watering
2. Contact Dermatitis:-
18. 3.Herpes zoster ophthalmicus:-
• Is a viral disease characterized by a
unilateral painful skin rash in one or
more dermatome distributions of the
fifth cranial nerve (trigeminal nerve),
shared by the eye and ocular adnexa.
• Symptoms- Painful forehead rashes,
severy ocular pain, eyelid edema,
photophobia,
19. 4.Blepharitis:-
An inflammation of the eyelid that affects
the eyelashes or tear production.
A• Squamous blepharitis:-
-Hyperemia of lid margins
– White dandruff-like scales on the lid margins
.
– Falling of eyelashes (madarosis)
– Thickening of the lid margins
-Redness ,photophobia
20. B. Ulcerative blepharitis:-
Ulcerative blepharitis is usually caused by bacterial infection
(usually staphylococcal) of the eyelid margin at the origins of
the eyelashes.
It may also be due to virus ( herpes simplex).
- Soreness of the lid margins .
– Loss of eyelashes
– Yellow crust at the root of the eyelashes with matting .
– Small ulcers at the base of the crust ,if remove it caused
bleeding.
21. 5.Meibomianitis:-
•Chronic infection of the meibomian
glands .
•Occurs in the middle age
• White, frothy secretion on the
eyelid margins and at the outer
canthus (seborrhea)
•Plugged duct opening and vertical
yellowish streaks shining through
the conjunctiva
22. 6.Stye(Hordeolum):-
External hordeolum:-
• An external hordeolum arises from a
blockage with secondary inflammation of the
Zeiss or Moll sebaceous glands of the eyelid.
• A swollen area at the lid margin .
• A whitish, round, raised pus point at eyelash
root.
• Causes:- The infection is most often caused
by Staphylococcus bacteria.
23. Internal hordeolum:-
*An internal stye (hordeolum) is an inflamed
and infected oil gland(meibomian gland) on
the inner edge of the eyelid.
• Symptoms include - eyelid pain,
tenderness and swelling,redness.
• Causes-
Most common causes infection of the
bacteria (staphylococcus).
24. 7.Chalazion:-
• A chronic nonspecific inflammatory
granuloma of the meibomian gland .
• Painless nodular swelling of the
eyelid.
•Tarsal conjunctiva underneath the
nodule is velvety red or purple and
slightly elevated
25. PTOSIS
•Drooping of the eyelid.
• It is unilateral or bilateral and
Partial or complete.
1. Mild ptosis – 2mm
2. Moderate – 3mm
3. Severe ptosis - 4mm
26. Other lid condition
1.Lid edema:-
• Diffuse edematous swelling of the
eyelids .
• May be associated with conjunctival
chemosis.
Causes:-
-Conjunctivitis
-Blepharitis
-Acute dacryocystitis
-Insect bite
27. 2.Lagaphthalmos:-
Lagophthalmos is the incomplete or
defective closure of the eyelids.
Causes:-
A. Injury
B. Bells Palsy
C. Autoimmune disease
D. Infection
28. 3.Blepharochalasis:-
Blepharochalasis is a inflamation that
causes painless swelling in the
eyelids.
Causes-
A. Puberty
B. Menstruation
C. Fatigue
D. Stress
E. Infection causes fever
29. 4. Symblepharon:-
• Symblepharon is a pathologic condition
where the bulbar and palpebral
conjunctiva form an abnormal adhesion to
one another.
• Clinical features :-
-Redness.
-Tearing.
-Burning sensation.
-Foreign body sensation.
-Photophobia.
30. 5.Dermatochalasis:-
•The presence of loose and
redundant eyelid skin.
• Older individual; usually bilateral.
• Prolapse of the fat, mainly
temporally in the upper lid.
31. 6.Ecchymosis:-
•Racoon eye or ecchymosis or black
eye is caused by blood tracking into
periorbital tissues.
•Panda bear’ or ‘Raccoon
eyes’ sign when both lids are
involved as after a head injury or
severe whooping cough.
32. 7. Exanthelasma:-
•Raised, yellow plaques, most
coslowly found at the inner portion
of the upper eyelids rarely in lower
lid .
•May be associated with familial
hypercholesterole.
•Often symmetrical and progress
slowly.
•Treatment: Cosmetic surgery may
be tried.
33. 8.Basal Cell Papilloma
(Seborrheic Keratosis):-
•Common in middle-aged and elderly
People .
•Discrete, round, brownish or blackish
lesion with variegated surfac .
34. 9. Sebaceous Cyst:-
• Cysts of Zeis develop as a solitary
lesion at the base of an eyelash.
• Bilateral or Unilateral and multiple cyst
are more common .
• It is vary shape and size .
• Treatment – Excision biopsy .
35. 10. Meibomian Gland
Carcinoma:-
• Appears as a discrete, yellow, firm
nodule which is sometimes incorrectly
diagnosed as ‘recurrent chalazion’.
36. 11. Ankyloblepharon:-
• Ankyloblepharon is a medical condition,
defined as the adhesion of the edges of the
upper eyelid with the lower eyelid.
• Causes :- Chemical injury, thermal burns and
due to severy trauma .