This document discusses the diagnosis and management of cystic neoplasms of the pancreas through an evidence-based approach. It begins by classifying pancreatic cysts as neoplastic (including serous cystadenoma, serous cystadenocarcinoma, mucinous cystic neoplasm, intraductal papillary mucinous neoplasm, solid pseudopapillary tumors, and lymphangioma-like cysts) or non-neoplastic (including pseudocysts, infections, and congenital cysts). It then focuses on serous cystadenomas, mucinous cystic neoplasms, and intraductal papillary mucinous neoplasms, describing their histopathology, clinical