IBM DB2 with BLU Acceleration provides several key benefits for analytical workloads: 1) It is easy to implement and maintain, requiring only the creation of tables and loading of data. 2) It provides extreme data compression and column-oriented data storage for improved performance and reduced storage needs. 3) It utilizes several techniques like data skipping, multi-processor parallelism, and Single Instruction Multiple Data (SIMD) CPU instructions to further accelerate performance.