This document provides a biography and curriculum vitae for Dr. Maurice George Vincentius Maria Russel, a gastroenterologist in the Netherlands. It details his professional experience working at various hospitals since 1996, primarily focusing on inflammatory bowel disease and colorectal cancer. It also outlines his positions held, education history, research interests, publications, and administrative roles with professional societies.
Inflammatory Bowel Disease (IBD) is a multifactorial disorder with many different putative influences mediating disease onset, severity, progression and diminution. Spontaneous natural IBD is classically expressed as Crohn’s Disease (CD) and Ulcerative Colitis (UC) commonly found in primates; lymphoplasmocytic enteritis, eosinophilic gastritis and colitis, and ulcerative colitis with neuronal hyperplasia in dogs; and colitis in horses. Spontaneous inflammatory bowel disease has been noted in a
number of rodent models which differ in genetic strain background, induced mutation, microbiota influences and immunopathogenic pathways. Histological lesions in Crohn’s Disease feature noncaseating granulomatous inflammation while UC lesions typically exhibit ulceration, lamina propria inflammatory infiltrates and lack of granuloma development. Intestinal inflammation caused by CD and UC is also associated with increased incidence of intestinal neoplasia. Transgenic murine models have determined underlying etiological influences and appropriate therapeutic targets in IBD. This literature review will discuss current opinion and findings in spontaneous IBD, highlight selected transgenic rodent models of IBD and discuss their respective pathogenic mechanisms. It is very important to provide accommodation of induced putative deficits in activities of daily living and to assess discomfort and pain levels in the face of significant morbidity and/or mortality in these models. Epigenetic, environmental
(microbiome, metabolome) and nutritional factors are important in IBD pathogenesis, and evaluating ways in which they influence disease expression represent potential investigative approaches with the greatest potential for new discoveries.
Chronic gastritis is one of the most common diseases worldwide, with over half the global population estimated to have it currently. Helicobacter pylori infection acquired in childhood is the main cause, resulting in lifelong inflammation that progresses over decades from non-atrophic to atrophic gastritis. Atrophic gastritis destroys stomach mucosa and leads to dysfunction, increased cancer risk, and other severe outcomes like vitamin deficiencies. While prevalence has declined in developed countries, chronic gastritis remains an insidious disease with socioeconomic factors playing a key role in its transmission and epidemiology.
This seminar presentation summarizes key information about Hepatitis E virus (HEV) infection, including its characteristics, pathogenesis, clinical manifestations, epidemiology, diagnosis, prevention and control. HEV is an RNA virus that causes acute hepatitis and has four genotypes that infect humans and animals. It is transmitted fecal-orally and causes inflammation of the liver. Pregnant women are particularly susceptible and have a high mortality rate from HEV infection. Diagnosis involves microscopy, serological techniques like ELISA, and molecular techniques like PCR. Prevention focuses on proper sanitation, vaccination, and screening of animals that can transmit HEV like swine.
This document summarizes information about Salmonella enterica serotype Choleraesuis, including its epidemiology, pathogenesis, clinical manifestations, treatment, antimicrobial resistance, and vaccine development. Serotype Choleraesuis is primarily a pathogen of pigs that can cause invasive infections in humans. While it is an infrequent cause of human salmonellosis in Western countries, it is of particular concern in Asia, especially Taiwan, where it is one of the most common Salmonella serotypes isolated from human patients.
This study analyzed 232 patients with COVID-19 admitted to hospitals in China between January 19th and March 6th. The study found that 21% of patients experienced diarrhea, with those patients more likely to have severe symptoms and require intensive care. As the outbreak progressed, a greater proportion of patients experienced diarrhea. This suggests that gastrointestinal symptoms may be more common with COVID-19 than initially reported, and patients with diarrhea appear to have worse outcomes.
ALE Presentation: A Multiple Cause Analysis of Massachusetts Trends in HIV an...David Meyers
This document summarizes a study examining infectious disease mortality in Massachusetts from 2002-2011 using multiple cause of death data. The study analyzed deaths related to sepsis, influenza/pneumonia, hepatitis C, and HIV/AIDS. It found over 90,000 deaths were associated with these infectious diseases. Mortality rates and trends varied significantly by race, age, gender, and location. Spatial and temporal clustering methods identified populations and locations with higher mortality that should be public health priorities.
1. The document discusses various studies on HIV and AIDS. It examines how PCR techniques can detect HIV even in asymptomatic patients, and how HIV replicates poorly in macaque models due to species-specific differences in CD4 receptors and co-factors.
2. Accidental needlestick infections and transmission from dentists to patients are discussed as examples of HIV transmission. The depletion of CD4+ T-cells during clinical latency is also summarized, as HIV production outstrips the immune system's ability to replace cells.
3. The latency period allows the immune system to be depleted enough for opportunistic infections to take hold, as HIV remains latent in memory T-cells. Variability in clinical latency depends on viral mutations
This document provides a biography for Sherief Abd-Elsalam, including his educational background, work experience, publications, presentations, awards, and areas of expertise. It summarizes that he is a Senior Lecturer in Hepatology & Gastroenterology and Infectious diseases at Tanta University Faculty of Medicine in Egypt with a PhD in Hepatology & Gastroenterology and Infectious diseases. He has published numerous journal articles and books, presented at various international conferences, and serves as an editor or reviewer for several medical journals. His research focuses on Hepatology, gastroenterology and infectious diseases.
Inflammatory Bowel Disease (IBD) is a multifactorial disorder with many different putative influences mediating disease onset, severity, progression and diminution. Spontaneous natural IBD is classically expressed as Crohn’s Disease (CD) and Ulcerative Colitis (UC) commonly found in primates; lymphoplasmocytic enteritis, eosinophilic gastritis and colitis, and ulcerative colitis with neuronal hyperplasia in dogs; and colitis in horses. Spontaneous inflammatory bowel disease has been noted in a
number of rodent models which differ in genetic strain background, induced mutation, microbiota influences and immunopathogenic pathways. Histological lesions in Crohn’s Disease feature noncaseating granulomatous inflammation while UC lesions typically exhibit ulceration, lamina propria inflammatory infiltrates and lack of granuloma development. Intestinal inflammation caused by CD and UC is also associated with increased incidence of intestinal neoplasia. Transgenic murine models have determined underlying etiological influences and appropriate therapeutic targets in IBD. This literature review will discuss current opinion and findings in spontaneous IBD, highlight selected transgenic rodent models of IBD and discuss their respective pathogenic mechanisms. It is very important to provide accommodation of induced putative deficits in activities of daily living and to assess discomfort and pain levels in the face of significant morbidity and/or mortality in these models. Epigenetic, environmental
(microbiome, metabolome) and nutritional factors are important in IBD pathogenesis, and evaluating ways in which they influence disease expression represent potential investigative approaches with the greatest potential for new discoveries.
Chronic gastritis is one of the most common diseases worldwide, with over half the global population estimated to have it currently. Helicobacter pylori infection acquired in childhood is the main cause, resulting in lifelong inflammation that progresses over decades from non-atrophic to atrophic gastritis. Atrophic gastritis destroys stomach mucosa and leads to dysfunction, increased cancer risk, and other severe outcomes like vitamin deficiencies. While prevalence has declined in developed countries, chronic gastritis remains an insidious disease with socioeconomic factors playing a key role in its transmission and epidemiology.
This seminar presentation summarizes key information about Hepatitis E virus (HEV) infection, including its characteristics, pathogenesis, clinical manifestations, epidemiology, diagnosis, prevention and control. HEV is an RNA virus that causes acute hepatitis and has four genotypes that infect humans and animals. It is transmitted fecal-orally and causes inflammation of the liver. Pregnant women are particularly susceptible and have a high mortality rate from HEV infection. Diagnosis involves microscopy, serological techniques like ELISA, and molecular techniques like PCR. Prevention focuses on proper sanitation, vaccination, and screening of animals that can transmit HEV like swine.
This document summarizes information about Salmonella enterica serotype Choleraesuis, including its epidemiology, pathogenesis, clinical manifestations, treatment, antimicrobial resistance, and vaccine development. Serotype Choleraesuis is primarily a pathogen of pigs that can cause invasive infections in humans. While it is an infrequent cause of human salmonellosis in Western countries, it is of particular concern in Asia, especially Taiwan, where it is one of the most common Salmonella serotypes isolated from human patients.
This study analyzed 232 patients with COVID-19 admitted to hospitals in China between January 19th and March 6th. The study found that 21% of patients experienced diarrhea, with those patients more likely to have severe symptoms and require intensive care. As the outbreak progressed, a greater proportion of patients experienced diarrhea. This suggests that gastrointestinal symptoms may be more common with COVID-19 than initially reported, and patients with diarrhea appear to have worse outcomes.
ALE Presentation: A Multiple Cause Analysis of Massachusetts Trends in HIV an...David Meyers
This document summarizes a study examining infectious disease mortality in Massachusetts from 2002-2011 using multiple cause of death data. The study analyzed deaths related to sepsis, influenza/pneumonia, hepatitis C, and HIV/AIDS. It found over 90,000 deaths were associated with these infectious diseases. Mortality rates and trends varied significantly by race, age, gender, and location. Spatial and temporal clustering methods identified populations and locations with higher mortality that should be public health priorities.
1. The document discusses various studies on HIV and AIDS. It examines how PCR techniques can detect HIV even in asymptomatic patients, and how HIV replicates poorly in macaque models due to species-specific differences in CD4 receptors and co-factors.
2. Accidental needlestick infections and transmission from dentists to patients are discussed as examples of HIV transmission. The depletion of CD4+ T-cells during clinical latency is also summarized, as HIV production outstrips the immune system's ability to replace cells.
3. The latency period allows the immune system to be depleted enough for opportunistic infections to take hold, as HIV remains latent in memory T-cells. Variability in clinical latency depends on viral mutations
This document provides a biography for Sherief Abd-Elsalam, including his educational background, work experience, publications, presentations, awards, and areas of expertise. It summarizes that he is a Senior Lecturer in Hepatology & Gastroenterology and Infectious diseases at Tanta University Faculty of Medicine in Egypt with a PhD in Hepatology & Gastroenterology and Infectious diseases. He has published numerous journal articles and books, presented at various international conferences, and serves as an editor or reviewer for several medical journals. His research focuses on Hepatology, gastroenterology and infectious diseases.
Clinic Epidemiological Characteristics of Chronic Hepatitis C on the Backgrou...ijtsrd
Since the problem of the incidence of hepatitis C and tuberculosis in the population is still a very important and urgent problem not only in Uzbekistan and the whole world, we decided to study how these diseases flow against the background of each other. During our study, we observed 80 patients at the regional tuberculosis dispensary and at the regional infectious diseases hospital in Samarkand, which were divided into 2 clinical groups. Mukhammedova Fariza Farkhodovna "Clinic - Epidemiological Characteristics of Chronic Hepatitis C on the Background of Tuberculosis" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-5 | Issue-5 , August 2021, URL: https://www.ijtsrd.com/papers/ijtsrd45174.pdf Paper URL: https://www.ijtsrd.com/economics/other/45174/clinic--epidemiological-characteristics-of-chronic-hepatitis-c-on-the-background-of-tuberculosis/mukhammedova-fariza-farkhodovna
Ascaris lumbricoides and other Gastrointestinal Helminthic Parasites among Qe...iosrjce
IOSR Journal of Dental and Medical Sciences is one of the speciality Journal in Dental Science and Medical Science published by International Organization of Scientific Research (IOSR). The Journal publishes papers of the highest scientific merit and widest possible scope work in all areas related to medical and dental science. The Journal welcome review articles, leading medical and clinical research articles, technical notes, case reports and others.
The document discusses hepatitis B virus (HBV) infection in Vietnam. HBV is a major public health problem globally and in Asia. In Vietnam, the HBV surface antigen (HBsAg) carrier rate is between 10-25%, one of the highest in the world. Mother-to-child transmission during childbirth is a major route of HBV infection. The study aims to evaluate the immune response to hepatitis B vaccination in infants born to HBsAg-positive mothers in Vietnam. It examines the current status of HBV infection in newborns and assesses the relationship between maternal and cord blood HBV markers and infant immune response after full vaccination.
Robert Koch discovered the causative agent of tuberculosis (TB) in 1882. TB continues to be a major global health problem, especially in low and middle income countries. TB is caused by Mycobacterium tuberculosis and can affect the lungs and other parts of the body. It ranges from latent asymptomatic infection to active symptomatic disease which can be life threatening and transmissible. Standard treatment involves several antimicrobial drugs but drug resistance is a major issue. Efforts are ongoing to develop better diagnostics, treatments, vaccines and strategies to end the global TB epidemic.
Alta frequenza di prostatite batterica cronica e non infiammatoria in pazient...MerqurioEditore_redazione
This study examined the relationship between prostatitis syndrome (PS) and irritable bowel syndrome (IBS) in infertile patients. The study found:
1) Around 30% of patients being evaluated for either PS or IBS were also diagnosed with the other condition.
2) Patients with both PS and IBS had more severe symptoms than those with only one condition, as measured by symptom scoring indexes.
3) Patients with both PS and IBS were more likely to have chronic bacterial prostatitis than those with only PS.
So in summary, this study found a high frequency of patients having both PS and IBS. Those with both conditions tended to have more severe symptoms and were more
A field and statistical study on the spread of Tuberculosis in various distri...iosrjce
IOSR Journal of Pharmacy and Biological Sciences(IOSR-JPBS) is a double blind peer reviewed International Journal that provides rapid publication (within a month) of articles in all areas of Pharmacy and Biological Science. The journal welcomes publications of high quality papers on theoretical developments and practical applications in Pharmacy and Biological Science. Original research papers, state-of-the-art reviews, and high quality technical notes are invited for publications.
The document provides World Gastroenterology Organisation global guidelines on celiac disease from April 2012. It was reviewed by an international team and covers definitions, epidemiology, diagnosis, and management of celiac disease. Key points include that celiac disease affects genetically predisposed individuals and is triggered by ingestion of gluten. Diagnosis requires histological changes in intestinal biopsy and positive celiac disease serology or response to gluten-free diet. Management involves strict lifelong gluten-free diet to avoid complications.
Explainations for 20th Century Tuberculosis Decline- How the Public Gets It W...Spencer Davis
- The study surveyed 705 adults to assess their perceptions of why tuberculosis mortality declined in the 20th century. Approximately 52% attributed the decline to "modern medicine" while 22% attributed it to "vaccination." Few respondents cited public health interventions or improved social conditions.
- In reality, historical analysis shows the majority of the tuberculosis decline was due to improved social conditions like better housing and public health interventions rather than medical advances alone. The disease was already declining before treatments like antibiotics were developed.
- The public overly credits modern medicine and underappreciates the role of public health and social factors, which could hinder support for policies addressing social determinants of health.
Comparative seroprevalence and risk factors of toxoplasmosis among three subg...Alexander Decker
The document summarizes a study on the seroprevalence and risk factors of toxoplasmosis among three subgroups (pregnant women, immunocompromised patients, and immunocompetent controls) in Nigeria. The overall seroprevalence was found to be 31.5%. Pregnant women had significantly higher seroprevalence than the other two groups. Living with cats was found to increase the risk of toxoplasmosis four times compared to those not living with cats. Seroprevalence increased with age among pregnant women and immunocompromised patients.
This document discusses the potential role of enteroviruses, especially coxsackievirus B, in the development of type 1 diabetes mellitus (T1DM). It provides evidence from various studies that enteroviruses may infect and damage pancreatic beta cells, triggering an immune response and autoimmunity. While several viruses have been linked to T1DM, data implicates enteroviruses most strongly. The document also discusses potential mechanisms of viral persistence and the idea that enterovirus infection could initiate cycles of autoimmunity through presentation of viral and self-antigens.
Serological testing for coeliac disease in patients with i b s final.for publ...Shendy Sherif
This study aimed to estimate the prevalence of celiac disease in adult Saudi patients with symptoms of irritable bowel syndrome (IBS). 320 Arab patients meeting Rome III criteria for IBS without other conditions underwent testing for celiac disease including serological tests and biopsy where indicated. Serological testing found positivity in 15 patients (4.69%) and biopsy confirmed celiac disease in 11 patients (3.49%). Patients with positive serology had more severe gastrointestinal symptoms and lower nutritional parameters than negative patients, and symptoms and parameters improved with a gluten-free diet. The study concludes that celiac disease can be misdiagnosed as IBS and screening for it in IBS patients should be considered.
Cryptic Disseminated Tuberculosis: a Secondary Analysis of Previous Hospital-...fahmi khan
The main purpose of this study was to describe the demographic and clinical features of cryptic disseminated TB; it was also aimed to shed light on diagnostic test, procedure results, organ involvement, and outcomes of cryptic disseminated TB in patients with confirmed disseminated TB.
This study found that patients with type 2 diabetes mellitus in Ghana had a 46% increased risk of infection with the malaria parasite Plasmodium falciparum compared to people without diabetes. While most malaria infections detected were asymptomatic and only found by PCR testing, the risk of infection was higher in people with diabetes and increased with higher blood glucose levels. As diabetes prevalence increases in sub-Saharan Africa, more people may be at risk for malaria infection due to the immune dysfunction caused by diabetes.
Prevalence of Intestinal Parasitic Infections among Patients Attended to Alri...CrimsonpublishersCJMI
Prevalence of Intestinal Parasitic Infections among Patients Attended to Alribat University hospital, Khartoum State, Sudan, 2017 by Mohammed HMN in Cohesive Journal of Microbiology & Infectious Disease
This document lists 40 publications with the author Yong Gao. Many of the publications are about HIV and hepatitis C virus (HCV) research including studies on:
1) Demonstrating the safety of a killed whole-HIV vaccine in a clinical trial and its ability to enhance anti-HIV antibody responses.
2) Characterizing macaque infection by a clone from a diverse SHIVenv pool derived from acute HIV infections.
3) Studying pathogenic infection of rhesus macaques by an evolving SIV-HIV derived from CCR5-using envelope genes of acute HIV infections.
4) Research on HIV diversity, recombination, and disease progression.
This study investigated the prevalence of two intestinal parasites, Dientamoeba fragilis and Blastocystis, in subjects with and without irritable bowel syndrome (IBS) symptoms over a 1-year period. Stool samples from 328 subjects in 2010 found parasites in 44.5% of subjects, significantly less in those with IBS compared to asymptomatic controls. D. fragilis was found in 30.1% of subjects and Blastocystis in 18.9%, both more prevalent in controls. Follow-up of 275 subjects in 2011 found no significant difference in gastrointestinal symptom development between those initially infected or uninfected with the parasites. The study concludes that harboring D. fragilis or Blastocystis does
A poster on the incidence and prevalence of Blastocystis and Dientamoeba in IBS patients and controls. Presented by Laura Rindom Krogsgaard (MD, PhD student) at the United European Gastroenterology Week in Berlin, 2013.
NAFDL: un approccio clinico multidisciplinareGiancarlo Ralli
This document summarizes information about non-alcoholic fatty liver disease (NAFLD). It begins by defining NAFLD as a spectrum of liver disease ranging from simple fatty liver or steatosis to non-alcoholic steatohepatitis (NASH) and cirrhosis. It then discusses the global prevalence of NAFLD, key risk factors like obesity, diabetes, genetic factors, and demographic information. Mortality risks associated with NAFLD are also summarized, showing increased risks of death from liver-related causes and all-cause mortality correlated with fibrosis stage. The document concludes by noting NAFLD is now considered a systemic disease with potential extrahepatic manifestations affecting other organ systems.
Juvenile Polyposis Syndrome (JPS) is a rare genetic disease characterized by the presence of the juvenile hamartomatous polyps. The condition is caused by germline mutation in the BMPR1A or the SMAD4 genes and it is inherited in an autosomal dominant manner. It predisposes affected persons to a high risk of malignant tumors, mainly colorectal and stomach cancers. The confi rmation of the diagnosis is based on genetic analysis. But at first, family history, pedigree, clinical criteria and Histopathological analysis guide to an inherited disease. We present here a Congolese patient with suggestive clinical and histopathological features which lead to the JPS.
This document describes two research projects being conducted at the Jordan Valley Innovation Center. The first project is developing high-performance supercapacitors using electroactive and conductive polymers that can store and deliver energy faster than batteries. The second project is creating a self-detoxifying fabric system that uses catalysts and electrodes to slowly generate and release hydrogen peroxide to continuously destroy toxic chemicals and bacteria on contact. Both projects aim to provide more efficient energy storage and safer decontamination technologies.
O documento discute vários líderes religiosos que se declaram como reencarnações de Jesus Cristo ou como messias. Alguns destes líderes fundaram novas seitas ou igrejas, enquanto outros atraíram milhares de seguidores ao redor do mundo com suas crenças não ortodoxas.
El documento describe 9 herramientas útiles para profesionales de redes sociales que fueron presentadas en el congreso Trending Tools 2015. Las herramientas incluyen Hootsuite, CoolTabs, Oraquo, Followthehashtag, Atribus, Alianzo, Bluumi, Sociack y TweetBinder, las cuales pueden usarse para gestionar campañas, analizar datos, medir desempeño, identificar influencers y tendencias, y monitorear conversaciones en redes sociales.
Clinic Epidemiological Characteristics of Chronic Hepatitis C on the Backgrou...ijtsrd
Since the problem of the incidence of hepatitis C and tuberculosis in the population is still a very important and urgent problem not only in Uzbekistan and the whole world, we decided to study how these diseases flow against the background of each other. During our study, we observed 80 patients at the regional tuberculosis dispensary and at the regional infectious diseases hospital in Samarkand, which were divided into 2 clinical groups. Mukhammedova Fariza Farkhodovna "Clinic - Epidemiological Characteristics of Chronic Hepatitis C on the Background of Tuberculosis" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-5 | Issue-5 , August 2021, URL: https://www.ijtsrd.com/papers/ijtsrd45174.pdf Paper URL: https://www.ijtsrd.com/economics/other/45174/clinic--epidemiological-characteristics-of-chronic-hepatitis-c-on-the-background-of-tuberculosis/mukhammedova-fariza-farkhodovna
Ascaris lumbricoides and other Gastrointestinal Helminthic Parasites among Qe...iosrjce
IOSR Journal of Dental and Medical Sciences is one of the speciality Journal in Dental Science and Medical Science published by International Organization of Scientific Research (IOSR). The Journal publishes papers of the highest scientific merit and widest possible scope work in all areas related to medical and dental science. The Journal welcome review articles, leading medical and clinical research articles, technical notes, case reports and others.
The document discusses hepatitis B virus (HBV) infection in Vietnam. HBV is a major public health problem globally and in Asia. In Vietnam, the HBV surface antigen (HBsAg) carrier rate is between 10-25%, one of the highest in the world. Mother-to-child transmission during childbirth is a major route of HBV infection. The study aims to evaluate the immune response to hepatitis B vaccination in infants born to HBsAg-positive mothers in Vietnam. It examines the current status of HBV infection in newborns and assesses the relationship between maternal and cord blood HBV markers and infant immune response after full vaccination.
Robert Koch discovered the causative agent of tuberculosis (TB) in 1882. TB continues to be a major global health problem, especially in low and middle income countries. TB is caused by Mycobacterium tuberculosis and can affect the lungs and other parts of the body. It ranges from latent asymptomatic infection to active symptomatic disease which can be life threatening and transmissible. Standard treatment involves several antimicrobial drugs but drug resistance is a major issue. Efforts are ongoing to develop better diagnostics, treatments, vaccines and strategies to end the global TB epidemic.
Alta frequenza di prostatite batterica cronica e non infiammatoria in pazient...MerqurioEditore_redazione
This study examined the relationship between prostatitis syndrome (PS) and irritable bowel syndrome (IBS) in infertile patients. The study found:
1) Around 30% of patients being evaluated for either PS or IBS were also diagnosed with the other condition.
2) Patients with both PS and IBS had more severe symptoms than those with only one condition, as measured by symptom scoring indexes.
3) Patients with both PS and IBS were more likely to have chronic bacterial prostatitis than those with only PS.
So in summary, this study found a high frequency of patients having both PS and IBS. Those with both conditions tended to have more severe symptoms and were more
A field and statistical study on the spread of Tuberculosis in various distri...iosrjce
IOSR Journal of Pharmacy and Biological Sciences(IOSR-JPBS) is a double blind peer reviewed International Journal that provides rapid publication (within a month) of articles in all areas of Pharmacy and Biological Science. The journal welcomes publications of high quality papers on theoretical developments and practical applications in Pharmacy and Biological Science. Original research papers, state-of-the-art reviews, and high quality technical notes are invited for publications.
The document provides World Gastroenterology Organisation global guidelines on celiac disease from April 2012. It was reviewed by an international team and covers definitions, epidemiology, diagnosis, and management of celiac disease. Key points include that celiac disease affects genetically predisposed individuals and is triggered by ingestion of gluten. Diagnosis requires histological changes in intestinal biopsy and positive celiac disease serology or response to gluten-free diet. Management involves strict lifelong gluten-free diet to avoid complications.
Explainations for 20th Century Tuberculosis Decline- How the Public Gets It W...Spencer Davis
- The study surveyed 705 adults to assess their perceptions of why tuberculosis mortality declined in the 20th century. Approximately 52% attributed the decline to "modern medicine" while 22% attributed it to "vaccination." Few respondents cited public health interventions or improved social conditions.
- In reality, historical analysis shows the majority of the tuberculosis decline was due to improved social conditions like better housing and public health interventions rather than medical advances alone. The disease was already declining before treatments like antibiotics were developed.
- The public overly credits modern medicine and underappreciates the role of public health and social factors, which could hinder support for policies addressing social determinants of health.
Comparative seroprevalence and risk factors of toxoplasmosis among three subg...Alexander Decker
The document summarizes a study on the seroprevalence and risk factors of toxoplasmosis among three subgroups (pregnant women, immunocompromised patients, and immunocompetent controls) in Nigeria. The overall seroprevalence was found to be 31.5%. Pregnant women had significantly higher seroprevalence than the other two groups. Living with cats was found to increase the risk of toxoplasmosis four times compared to those not living with cats. Seroprevalence increased with age among pregnant women and immunocompromised patients.
This document discusses the potential role of enteroviruses, especially coxsackievirus B, in the development of type 1 diabetes mellitus (T1DM). It provides evidence from various studies that enteroviruses may infect and damage pancreatic beta cells, triggering an immune response and autoimmunity. While several viruses have been linked to T1DM, data implicates enteroviruses most strongly. The document also discusses potential mechanisms of viral persistence and the idea that enterovirus infection could initiate cycles of autoimmunity through presentation of viral and self-antigens.
Serological testing for coeliac disease in patients with i b s final.for publ...Shendy Sherif
This study aimed to estimate the prevalence of celiac disease in adult Saudi patients with symptoms of irritable bowel syndrome (IBS). 320 Arab patients meeting Rome III criteria for IBS without other conditions underwent testing for celiac disease including serological tests and biopsy where indicated. Serological testing found positivity in 15 patients (4.69%) and biopsy confirmed celiac disease in 11 patients (3.49%). Patients with positive serology had more severe gastrointestinal symptoms and lower nutritional parameters than negative patients, and symptoms and parameters improved with a gluten-free diet. The study concludes that celiac disease can be misdiagnosed as IBS and screening for it in IBS patients should be considered.
Cryptic Disseminated Tuberculosis: a Secondary Analysis of Previous Hospital-...fahmi khan
The main purpose of this study was to describe the demographic and clinical features of cryptic disseminated TB; it was also aimed to shed light on diagnostic test, procedure results, organ involvement, and outcomes of cryptic disseminated TB in patients with confirmed disseminated TB.
This study found that patients with type 2 diabetes mellitus in Ghana had a 46% increased risk of infection with the malaria parasite Plasmodium falciparum compared to people without diabetes. While most malaria infections detected were asymptomatic and only found by PCR testing, the risk of infection was higher in people with diabetes and increased with higher blood glucose levels. As diabetes prevalence increases in sub-Saharan Africa, more people may be at risk for malaria infection due to the immune dysfunction caused by diabetes.
Prevalence of Intestinal Parasitic Infections among Patients Attended to Alri...CrimsonpublishersCJMI
Prevalence of Intestinal Parasitic Infections among Patients Attended to Alribat University hospital, Khartoum State, Sudan, 2017 by Mohammed HMN in Cohesive Journal of Microbiology & Infectious Disease
This document lists 40 publications with the author Yong Gao. Many of the publications are about HIV and hepatitis C virus (HCV) research including studies on:
1) Demonstrating the safety of a killed whole-HIV vaccine in a clinical trial and its ability to enhance anti-HIV antibody responses.
2) Characterizing macaque infection by a clone from a diverse SHIVenv pool derived from acute HIV infections.
3) Studying pathogenic infection of rhesus macaques by an evolving SIV-HIV derived from CCR5-using envelope genes of acute HIV infections.
4) Research on HIV diversity, recombination, and disease progression.
This study investigated the prevalence of two intestinal parasites, Dientamoeba fragilis and Blastocystis, in subjects with and without irritable bowel syndrome (IBS) symptoms over a 1-year period. Stool samples from 328 subjects in 2010 found parasites in 44.5% of subjects, significantly less in those with IBS compared to asymptomatic controls. D. fragilis was found in 30.1% of subjects and Blastocystis in 18.9%, both more prevalent in controls. Follow-up of 275 subjects in 2011 found no significant difference in gastrointestinal symptom development between those initially infected or uninfected with the parasites. The study concludes that harboring D. fragilis or Blastocystis does
A poster on the incidence and prevalence of Blastocystis and Dientamoeba in IBS patients and controls. Presented by Laura Rindom Krogsgaard (MD, PhD student) at the United European Gastroenterology Week in Berlin, 2013.
NAFDL: un approccio clinico multidisciplinareGiancarlo Ralli
This document summarizes information about non-alcoholic fatty liver disease (NAFLD). It begins by defining NAFLD as a spectrum of liver disease ranging from simple fatty liver or steatosis to non-alcoholic steatohepatitis (NASH) and cirrhosis. It then discusses the global prevalence of NAFLD, key risk factors like obesity, diabetes, genetic factors, and demographic information. Mortality risks associated with NAFLD are also summarized, showing increased risks of death from liver-related causes and all-cause mortality correlated with fibrosis stage. The document concludes by noting NAFLD is now considered a systemic disease with potential extrahepatic manifestations affecting other organ systems.
Juvenile Polyposis Syndrome (JPS) is a rare genetic disease characterized by the presence of the juvenile hamartomatous polyps. The condition is caused by germline mutation in the BMPR1A or the SMAD4 genes and it is inherited in an autosomal dominant manner. It predisposes affected persons to a high risk of malignant tumors, mainly colorectal and stomach cancers. The confi rmation of the diagnosis is based on genetic analysis. But at first, family history, pedigree, clinical criteria and Histopathological analysis guide to an inherited disease. We present here a Congolese patient with suggestive clinical and histopathological features which lead to the JPS.
This document describes two research projects being conducted at the Jordan Valley Innovation Center. The first project is developing high-performance supercapacitors using electroactive and conductive polymers that can store and deliver energy faster than batteries. The second project is creating a self-detoxifying fabric system that uses catalysts and electrodes to slowly generate and release hydrogen peroxide to continuously destroy toxic chemicals and bacteria on contact. Both projects aim to provide more efficient energy storage and safer decontamination technologies.
O documento discute vários líderes religiosos que se declaram como reencarnações de Jesus Cristo ou como messias. Alguns destes líderes fundaram novas seitas ou igrejas, enquanto outros atraíram milhares de seguidores ao redor do mundo com suas crenças não ortodoxas.
El documento describe 9 herramientas útiles para profesionales de redes sociales que fueron presentadas en el congreso Trending Tools 2015. Las herramientas incluyen Hootsuite, CoolTabs, Oraquo, Followthehashtag, Atribus, Alianzo, Bluumi, Sociack y TweetBinder, las cuales pueden usarse para gestionar campañas, analizar datos, medir desempeño, identificar influencers y tendencias, y monitorear conversaciones en redes sociales.
10 Manejo inicial del paciente intoxicado, Dr Hernan TaleroLuis Vargas
Este documento trata sobre el manejo del paciente intoxicado. Describe la clasificación clínica de las intoxicaciones agudas según cuatro parámetros como la dosis del tóxico, el tiempo transcurrido desde la exposición, el estado general y el estado de conciencia. También cubre las vías principales de exposición, las sustancias más frecuentes como causa de intoxicación, consideraciones en la reanimación, metas de tratamiento y centros de información toxicológica. Además, detalla los síndromes tóxicos agudos más
The document summarizes a job training program that helps unemployed individuals in the Humber region of the UK become qualified lorry/truck drivers. The program has already helped 18 jobseekers complete training and get jobs with local logistics companies. It is now being expanded with additional funding to place more trainees with companies across the wider Humber region, including Hull and East Riding of Yorkshire. The program aims to boost the local logistics industry by providing a trained driver workforce as the sector is a major employer in the regional economy.
This document summarizes a presentation on prognostication in COPD patients. It discusses how COPD patients often die, trajectories of death, factors that impact prognosis like comorbidities and functional status, and challenges with prognostication. It also reviews prognostic scoring systems like BODE and ADO and their limitations. Finally, it discusses implications for improving COPD care through a palliative care approach, better access to support services, and enhanced prognostic tools to predict outcomes in individual patients.
Presentazione a cura del Professor Franco Scaldaferri - M.A.S.T.E.R. ECM in Gastroenterologia: Approccio personalizzato alla complessità in Gastroenterologia - Fondazione Santa Lucia - Roma 19/01/2018
This document provides a summary of the background and qualifications of Dr. Jérôme LARCHÉ. He is an internist and medical intensivist based in France with over 25 years of experience. His experience includes serving as head of the intensive care unit at Narbonne General Hospital from 2011-2014 and founding a non-profit organization focused on bacteriophage research in 2009. He has published numerous peer-reviewed articles and holds masters degrees focusing on tropical diseases and cardiology. His areas of expertise include ICU medical care and management as well as extrarenal support devices.
Gabriella Di Stefano has over 15 years of experience in research and instruction. She holds a PhD in Translational Medicine from the University of L'Aquila and has worked as a research scholar at Case Western Reserve University. Her research focuses on skin wound healing, platelet rich plasma, and inflammatory bowel diseases. She has published papers in peer-reviewed journals and presented her work at conferences.
This document discusses inflammatory bowel disease (IBD) and its relevance to primary care clinicians. Key points include:
- IBD is common in the US, affecting hundreds of thousands annually with billions in costs. Delayed diagnosis can lead to worse outcomes.
- Primary care clinicians play an important role in initial recognition of IBD symptoms, ongoing health maintenance for IBD patients, and monitoring for complications from immunosuppressive therapies.
- Diagnosing IBD requires considering symptoms, labs, endoscopy, and radiography. Treatment goals include inducing remission and mucosal healing through a treat-to-target approach using medications like 5-ASAs, corticosteroids, immunomodulators,
This document summarizes inflammatory bowel disease (IBD) and reviews transgenic rodent models of IBD. It discusses how IBD is a multifactorial disorder involving genetic, environmental, and immunological factors. Transgenic murine models have helped determine underlying etiological influences and therapeutic targets in IBD. The document reviews the pathogenesis of IBD and highlights selected transgenic rodent models, discussing their pathogenic mechanisms and contributions to understanding IBD.
This document presents consensus guidelines from an expert panel on the medical management of pediatric Crohn's disease. It aims to provide evidence-based guidance for treating children and adolescents based on a review of existing literature. The guidelines discuss several key points:
- Children with Crohn's disease often have a more complicated disease course than adults, impacting growth, development, and long-term outcomes.
- Exclusive enteral nutrition is the preferred induction therapy for children who have not finished growing, due to its safety profile over corticosteroids.
- Most pediatric Crohn's patients require long-term immunomodulator therapy to maintain remission.
- Certain high-risk factors may warrant an early "top-
This document discusses tuberculosis (TB) and strategies for identifying and managing TB among hard-to-reach groups. It provides historical context on TB in Europe in the late 19th/early 20th century and modern challenges. It also describes a study that found homelessness is an independent risk factor for infectious and drug-resistant TB in London. The document advocates active case finding using mobile X-rays and outlines an outreach program that provides on-site testing, treatment, and social services and has achieved high treatment completion rates. It acknowledges the need to address social determinants of health and move from individual to societal approaches in TB elimination efforts.
This document lists Petra Roubos' publications, including 10 full papers published in peer-reviewed journals on topics related to microbiology and intestinal health. It also lists 7 conference papers presented between 2013-2015 related to microbiota, intestinal barrier function, and diarrhea in pigs. The list covers publications in book chapters and as lead author and co-author.
Ibd twin research wingate institute talkgoldcat2013
This document discusses the role of twin studies in IBD research. It begins with a brief history of twin studies dating back to 1875 and how they have been used to distinguish the roles of nature vs nurture in disease. The document then reviews how twin studies of IBD have shown a genetic basis and environmental components for both Crohn's and ulcerative colitis. It also discusses new molecular techniques being applied to twin studies, such as analyzing the microbiome, epigenetics, metabolomics and miRNA expression in twins concordant and discordant for IBD. The document promotes the ongoing UK IBD Twin registry and biobank for continued twin research in the omics era.
Clostridium difficile is a gram-positive, spore-forming anaerobic bacillus that can cause infectious diarrhea. Antibiotics reduce normal gut flora allowing C. difficile to grow and produce toxins, leading to symptoms ranging from mild diarrhea to pseudomembranous colitis. Diagnosis involves toxin detection in stool samples. Treatment involves discontinuing the precipitating antibiotic when possible and using metronidazole, vancomycin, or fidaxomicin to suppress C. difficile growth. Relapse can occur in 20-30% of cases. Prevention focuses on prudent antibiotic use and infection control.
This document provides an overview of comorbidities that are commonly associated with chronic obstructive pulmonary disease (COPD). It defines comorbidity and discusses how comorbidities have increasingly been recognized as important in COPD. The document then examines several specific comorbidities in more detail, including cardiovascular disease, lung cancer, diabetes, obesity, cachexia, osteoporosis, depression and anxiety, pneumonia and gastroesophageal reflux disease. It provides data on the prevalence of these comorbidities in COPD patients and their impact on outcomes. The role of systemic inflammation in COPD in potentially contributing to the development of comorbidities is also discussed.
This document provides a summary of Prof. Hakan Erdem's professional experience and qualifications. It outlines that he has over 20 years of experience in infectious diseases and clinical microbiology. He founded ID-IRI, an international clinical research platform, in 2008. He has published over 100 papers in international journals and textbook sections on topics like brucellosis, tuberculosis, and community-acquired pneumonia. He has worked in leadership roles at several hospitals and universities in Turkey.
This document is the curriculum vitae of Jacques Duranteau, MD, PhD. It summarizes his educational background, medical training, areas of research interest, board certifications, membership in scientific societies, positions held, and publications. Duranteau received his MD from Necker Enfants Malades, University Paris V in 1986 and has since held various positions in anesthesiology and intensive care in France. His research focuses on cardiovascular management of critically ill patients, including tissue perfusion and oxygenation. He has over 35 publications in peer-reviewed journals.
This document is the curriculum vitae of Jacques Duranteau, MD, PhD. It summarizes his educational background, including medical school and postgraduate training. It also lists his areas of research interest, which focus on cardiovascular management of critically ill patients. Finally, it provides a list of 27 publications with Duranteau as an author.
pancrease & glucose homeostasisNew microsoft office power point presentationManoj Mishra
This document summarizes a study on the prevalence of Helicobacter pylori infection in patients with peptic ulcer disease in Manipur, India. The study found a prevalence of H. pylori infection of 20% among 60 peptic ulcer patients, which is significantly lower than other studies in India. Positive H. pylori status was significantly associated with non-vegetarian diet and not taking anti-ulcer drugs in the past week. The study concludes that a rapid antibody test kit is a suitable, cheap, and reliable screening technique for H. pylori infection in peptic ulcer patients.
This document provides a summary of Dr. Jérôme LARCHÉ's background and qualifications. It outlines his medical education and experience as an internist, intensivist, and head of an intensive care unit. It also details his research focusing on bacteriophages and antibiotic resistance. Additionally, it lists his political science education and experience analyzing security, conflicts, and civil-military relations. The document serves to introduce Dr. LARCHÉ's extensive medical and policy expertise.
This document lists 72 publications by G.J.L.H. van Leenders. The publications are listed in reverse chronological order from 2012 to 2010 and include journal articles, book chapters, and other published works. The publications cover a range of topics including prostate cancer, bladder cancer, coronary artery imaging, and cancer biomarkers. Many of the publications are in high impact factor journals like European Urology, British Journal of Cancer, and Human Molecular Genetics.
1. Dr. Maurice George Vincentius Maria Russel
Hofstedeweg 78, 7535 CW, Enschede
Date of birth: 1 March 1958
BIG registration nr: 59023606201
Email: m.russel@mst.nl
Mobile: +316 29355744
PROFESSIONAL EXPERIENCE
2003-Current Medical Spectrum Twente (MST), Dept. of Gastroenterology, Enschede, NL (Netherlands)
Gastroenterologist, area of interest: inflammatory bowel disease (IBD) and colorectal cancer.
Positions:
2014-current: chairman cooperation medical specialists MST
2011-current: chairman of gastroenterology department MST
2007-2011: co-chairman department internal medicine/gastroenterology MST
2003-2012: vice-teacher gastroenterology MST
1996-2003 University Hospital Maastricht, dept. of internal medicine/gastroenterology, Maastricht, NL
Gastroenterologist, staff member (university teacher) gastroenterology
Positions:
2001-2003: board member internal medicine/gastroenterology
1998-2002: internship coordinator internal medicine/gastroenterology
1997-2003: outpatient commission internal medicine/gastroenterology
1997-2003: scientific director European Concerted action on IBD
1996-2003: scientific director South Limburg Project on IBD
FORMAL EDUCATION
1993-1996 University Hospital Maastricht, dept. of gastroenterology,Maastricht,NL
Traineeship gastroenterology
Positions:
1994-1996: tutorabdominal complaints
1993-1996: tutorcomputer assisted education in gastroenterology
1988-1992 Atrium Medical Centre, dept. of internal medicine, Heerlen, NL
Traineeship internal medicine
Positions:
1989-1991: secretary general education/trainee committee
1990-1992: chairman trainee association
1978-1986 Medical study,University of Amsterdam, NL
1977-1978 Medical study,University of Antwerp (Belgium)
1976-1977 Exchange student USA (American Field Service)
1970-1976 Gymnasium B, Roermond, NL
OTHER ADMINISTRATIVE POSITIONS
2010-current Symposium committee, Dutch Society of Gastroenterology
2006-2011 Chairman committee on Quality Affairs, Dutch Society of Gastroenterology
2005-2006 Chairman committee on Guidelines, Dutch Society of Gastroenterology
2004-2006 Member committee of certification, Dutch Society of Gastroenterology
2003-2005 Board member of the Dutch IBD Research Group (Initiative on Crohn and Colitis ICC)
SCIENTIFIC RESEARCH
2014-current IBDREAM study
1997 Thesis: Incidence, Risk factors and Quality of Life in IBD, University of Maastricht, NL
1997-2006 Co-promotor in six theses on IBD, University of Maastricht, NL
1993-current Several (>20) researcher and pharmaceutical initiated studies in the area of IBD
1993-2003 Research in epidemiology and quality of life in IBD
3. Publications (peer reviewed)
Scientific publications
1. van der Wiel SK, Kolkman JJ, Russel MG. Treatment of inflammatory bowel disease: what
if drug therapy fails?.Ned Tijdschr Geneeskd. 2014;158:A7589. Dutch.
2.van Bodegraven AA, Bravenboer N, Witte BI, Dijkstra G, van der Woude CJ, Stokkers PC,
Russel MG, Oldenburg B, Pierik M, Roos JC, van Hogezand RA, Dik VK, Oostlander AE,
Netelenbos JC, van de Langerijt L, Hommes DW, Lips P; Dutch Initiative on Crohn and
Colitis (ICC). Treatment of bone loss in osteopenic patients with Crohn's disease: a double-
blind, randomised trial of oral risedronate 35 mg once weekly or placebo, concomitant with
calcium and vitamin D supplementation Gut. 2014 Sep;63(9):1424-30.
3. Guloksuz S, Wichers M, Kenis G, Russel MG, Wauters A, Verkerk R, Arts B, van Os J.
Depressive symptoms in Crohn's disease: relationship with immune activation and tryptophan
availability. PLoS One. 2013;8(3):e60435.
4. Romberg-Camps MJ, Bol Y, Dagnelie PC, Hesselink-van de Kruijs MA, Kester AD,
Engels LG, van Deursen C, Hameeteman WH, Pierik M, Wolters F, Russel MG,
Stockbrügger RW. Fatigue and health-related quality of life in inflammatory bowel disease:
results from a population-based study in the Netherlands: the IBD-South Limburg cohort.
Inflamm Bowel Dis. 2010 Dec;16(12):2137-47.
5. van Asseldonk DP, Jharap B, Kuik DJ, de Boer NK, Westerveld BD, Russel MG, Kubben
FJ, van Bodegraven AA, Mulder CJ. Prolonged thioguanine therapy is well tolerated and safe
in the treatment of ulcerative colitis. Dig Liver Dis. 2011 Feb;43(2):110-5.
6. Juillerat P, Pittet V, Mottet C, Felley C, Gonvers JJ, Vader JP, Burnand B, Froehlich F,
Wolters FL, Stockbrügger RW, Michetti P; EC-IBD Group. Appropriateness of early
management of newly diagnosed Crohn's disease in a European population-based cohort.
Scand J Gastroenterol. 2010 Dec;45(12):1449-56.
7. Romberg-Camps MJ, Hesselink-van de Kruijs MA, Schouten LJ, Dagnelie PC, Limonard
CB, Kester AD, Bos LP, Goedhard J, Hameeteman WH, Wolters FL, Russel MG,
Stockbrügger RW.Inflammatory Bowel Disease in South Limburg (the Netherlands) 1991-
2002: Incidence, diagnostic delay, and seasonal variations in onset of symptoms.
J Crohns Colitis. 2009 Jun;3(2):115-24.
8. Romberg-Camps MJ, Dagnelie PC, Kester AD, Hesselink-van de Kruijs MA, Cilissen M,
Engels LG, Van Deursen C, Hameeteman WH, Wolters FL, Russel MG, Stockbrügger RW.
Influence of phenotype at diagnosis and of other potential prognostic factors on the course of
inflammatory bowel disease. Am J Gastroenterol. 2009 Feb;104(2):371-83.
9. van Hooft JE, Fockens P, Marinelli AW, Timmer R, van Berkel AM, Bossuyt PM,
Bemelman WA; Dutch Colorectal Stent Group. Early closure of a multicenter randomized
clinical trial of endoscopic stenting versus surgery for stage IV left-sided colorectal cancer.
Endoscopy. 2008 Mar;40(3):184-91.
4. 10. Wolters FL, Joling C, Russel MG, Sijbrandij J, De Bruin M, Odes S, Riis L, Munkholm P,
Bodini P, Ryan B, O'Morain C, Mouzas IA, Tsianos E, Vermeire S, Monteiro E, Limonard C,
Vatn M, Fornaciari G, Rodriguez D, Groot W, Moum B, Stockbrügger RW; European
Collaborative Study Group On Inflammatory Bowel Disease (EC-IBD). Treatment inferred
disease severity in Crohn's disease: evidence for a European gradient of disease course.
Scand J Gastroenterol. 2007 Mar;42(3):333-44.
11. Odes S, Vardi H, Friger M, Wolters F, Russel MG, Riis L, Munkholm P, Politi P, Tsianos
E, Clofent J, Vermeire S, Monteiro E, Mouzas I, Fornaciari G, Sijbrandij J, Limonard C, Van
Zeijl G, O'morain C, Moum B, Vatn M, Stockbrugger R; European Collaborative Study on
Inflammatory Bowel Disease. Cost analysis and cost determinants in a European
inflammatory bowel disease inception cohort with 10 years of follow-up evaluation.
Gastroenterology. 2006 Sep;131(3):719-28.
12. Wolters FL, Russel MG, Sijbrandij J, Schouten LJ, Odes S, Riis L, Munkholm P,
Langholz E, Bodini P, O'Morain C, Katsanos K, Tsianos E, Vermeire S, Van Zeijl G,
Limonard C, Hoie O, Vatn M, Moum B, Stockbrügger RW; European Collaborative Study
Group On Inflammatory Bowel Disease.Disease outcome of inflammatory bowel disease
patients: general outline of a Europe-wide population-based 10-year clinical follow-up study.
Scand J Gastroenterol Suppl. 2006;(243):46-54.
13. Corporaal S, Smit WM, Russel MG, van der Palen J, Boot H, Legdeur MC. Capecitabine,
epirubicin and cisplatin in the treatment of oesophagogastric adenocarcinoma. Neth J Med.
2006 May;64(5):141-6.
14. van der Sluijs Veer G, van den Hoven B, Russel MG, van den Bergh FA. Time-resolved
fluorimetric immunoassay of calprotectin: technical and clinical aspects in diagnosis of
inflammatory bowel diseases. Clin Chem Lab Med. 2006;44(3):292-8.
15. Wolters FL, van Zeijl G, Sijbrandij J, Wessels F, O'Morain C, Limonard C,
Russel MG, Stockbrugger RW. Internet-based data inclusion in a population-based European
collaborative follow-up study of inflammatory bowel disease patients: description of methods
used and analysis of factors influencing response rates. World J Gastroenterol.
2005;11(45):7152-8.
16. Goossens DA, Jonkers DM, Russel MG, Stobberingh EE, Stockbrugger RW.
The effect of a probiotic drink with Lactobacillus plantarum 299v on the
bacterial composition in faeces and mucosal biopsies of rectum and ascending
colon. Aliment Pharmacol Ther. 2006;23(2):255-63.
17. Wolters FL, Russel MG, Sijbrandij J, Ambergen T, Odes S, Riis L, Langholz E,
Politi P, Qasim A, Koutroubakis I, Tsianos E, Vermeire S, Freitas J, van Zeijl
G, Hoie O, Bernklev T, Beltrami M, Rodriguez D, Stockbrugger RW, Moum B. Phenotype at
diagnosis predicts recurrence rates in Crohn's disease. Gut. 2005 Dec 16;
18. Wolters FL, Russel MG, Sijbrandij J, Schouten LJ, Odes S, Riis L, Munkholm
P, Bodini P, O'morain C, Mouzas IA, Tsianos E, Vermeire S, Monteiro E, Limonard
C, Vatn M, Fornaciari G, Pereira S, Moum B, Stockbrugger RW. Crohn's disease: increased
mortality 10 years after diagnosis in a Europe-wide
5. population based cohort. Gut. 2006;55(4):510-8.
19. van der Hagen SJ, Baeten CG, Soeters PB, Beets-Tan RG, Russel MG, van Gemert
WG. Staged mucosal advancement flap for the treatment of complex anal fistulas:
pretreatment with noncutting Setons and in case of recurrent multiple abscesses
a diverting stoma. Colorectal Dis. 2005;7(5):513-8.
20. van der Hagen SJ, Baeten CG, Soeters PB, Russel MG, Beets-Tan RG, van Gemert WG.
Anti-TNF-alpha (infliximab) used as induction treatment in case of active proctitis in a
multistep strategy followed by definitive surgery of complex anal fistulas in Crohn's
disease: a preliminary report. Dis Colon Rectum. 2005Apr;48(4):758-67.
21. Goossens D, Jonkers D, Russel M, Thijs A, van den Bogaard A, Stobberingh E,
Stockbrugger R. Survival of the probiotic, L. plantarum 299v and its effects on the faecal
bacterial flora, with and without gastric acid inhibition. Dig LiverDis. 2005;37(1):44-50.
22. Ryan BM, Russel MG, Schurgers L, Wichers M, Sijbrandij J, Stockbrugger RW, Schoon E.
Effect of antitumour necrosis factor-alpha therapy on bone turnover in patients with active
Crohn's disease: a prospective study. Aliment Pharmacol Ther. 2004;20(8):851-7.
23. van der Eijk I, Vlachonikolis IG, Munkholm P, Nijman J, Bernklev T, Politi
P, Odes S, Tsianos EV, Stockbrugger RW, Russel MG; EC-IBD Study Group. The role of
quality of care in health-relatedquality of life in patients with IBD.
Inflamm Bowel Dis. 2004;10(4):392-8.
24. Wolters FL, Russel MG, Stockbrugger RW. Systematic review: has disease outcome in
Crohn's disease changed during the last four decades? Aliment Pharmacol Ther.
2004;20(5):483-96.
25. Van Der Eijk I, Verheggen FW, Russel MG, Buckley M, Katsanos K, Munkholm P, Engdahl
I, Politi P, Odes S, Fossen J, StockbruggerRW; European Collaborative
Study Group on Inflammatory Bowel Disease (EC-IBD). "Best practice" in inflammatory
bowel disease: an international survey and audit. Eur J Intern Med. 2004;15(2):113-120.
26. Goossens D, JonkersD, StobberinghE, van den Bogaard A, Russel M,
Stockbrugger R. Probiotics in gastroenterology: indications and future perspectives. Scand
J Gastroenterol Suppl. 2003;(239):15-23.
27. van den Bergh FA, KolkmanJJ, Russel MG, Vlaskamp RT, VermesI.
[Calprotectin: a fecal markerfordiagnosis and follow-upin patients with
chronic inflammatory bowel disease] Ned Tijdschr Geneeskd. 2003;147(48):2360-5.
Dutch.
28. GoossensD, Jonkers D, Russel M, Stobberingh E, Van Den Bogaard A, Stockbrugger R.
The effect of Lactobacillus plantarum 299v on the bacterial composition and metabolic
activity in faeces of healthy volunteers: a placebo-controlled study on the onset and
duration of effects.Aliment Pharmacol Ther. 2003 Sep1;18(5):495-505.
6. 29. Ryan BM, Russel MG, Langholz E, Stockbrugger RW. Aminosalicylates and colorectal
cancer in IBD: a not-so bitter pill to swallow. Am J Gastroenterol. 2003;98(8):1682-7.
30. Russel MG, Ryan BM, Dagnelie PC, de Rooij M, Sijbrandij J, Feleus A, Hesselink M, Muris
JW, Stockbrugger R. Insurance problems among inflammatory bowel disease patients:
results of a Dutch population based study. Gut. 2003;52(3):358-62.
31. Boonen A, Dagnelie PC, Feleus A, Hesselink MA, MurisJW, Stockbrugger RW,
Russel MG. The impact of inflammatory bowel diseaseon laborforceparticipation: results
of a population sampled case-control study. Inflamm Bowel Dis. 2002;8(6):382-9.
32. DamoiseauxJG, Bouten B, Linders AM, Austen J, Roozendaal C, Russel MG,
Forget PP, Tervaert JW. Diagnostic value of anti-Saccharomyces cerevisiae and
antineutrophil
cytoplasmic antibodies for inflammatory bowel disease: high prevalence in patients with
celiac disease.J Clin Immunol. 2002;22(5):281-8.
33. van Balkom BP, Schoon EJ, Stockbrugger RW, Wolters FL, van HogezandRA, van
Deventer SJ, Oldenburg B, van Dullemen HM, Russel MG. Effects of anti-tumour necrosis
factor-alpha therapy on thequality oflife in Crohn's disease.
Aliment Pharmacol Ther. 2002;16(6):1101-7.
34. van der Eijk I, Sixma H, Smeets T, Veloso FT, Odes S, Montague S, Fornaciari G, Moum B,
StockbruggerR, Russel M; European Collaborative Study Group on IBD.
Quality of health care in inflammatory bowel disease: development of a reliable
questionnaire (QUOTE-IBD) and first results. Am J Gastroenterol. 2001 Dec;96(12):3329-
36.
35. Salvarani C, Vlachonikolis IG, vanderHeijde DM, Fornaciari G, Macchioni
P, Beltrami M, Olivieri I, Di Gennaro F, Politi P, Stockbrugger RW, Russel MG;
European Collaborative IBD Study Group. Musculoskeletal manifestations in a population-
based cohort of inflammatory bowel disease patients. Scand J Gastroenterol.
2001;36(12):1307-13.
36. Russel MG, Stockbrugger RW.
[Epidemiological developments andinsights in chronic inflammatory bowel
diseases] Ned Tijdschr Geneeskd. 2001 Jul 28;145(30):1448-52. Review.
37. Fornaciari G, Salvarani C, Beltrami M, Macchioni P, Stockbrugger RW, Russel
MG. Muscoloskeletal manifestations in inflammatory bowel disease. Can J Gastroenterol.
2001 Jun;15(6):399-403.
38. Schoon EJ, van Nunen AB, WoutersRS, Stockbrugger RW, Russel MG.
Osteopenia and osteoporosis in Crohn's disease: prevalence in a Dutch
population-based cohort. Scand J Gastroenterol Suppl. 2000;(232):43-7.
39. Witte J, Shivananda S, Lennard-JonesJE, Beltrami M, Politi P, Bonanomi A,
Tsianos EV, Mouzas I, Schulz TB, Monteiro E, Clofent J, Odes S, Limonard CB,
7. Stockbrugger RW, Russel MG. Disease outcome in inflammatory bowel disease: mortality,
morbidity and therapeutic management of a 796-person inception cohort in the European
Collaborative Study on Inflammatory Bowel Disease (EC-IBD). Scand J Gastroenterol.
2000;35(12):1272-7.
40. Schoon EJ, Blok BM, Geerling BJ, Russel MG, StockbruggerRW, BrummerRJ.
Bone mineral density in patients with recently diagnosedinflammatory bowel
disease. Gastroenterology. 2000;119(5):1203-8.
41. van der Eijk I, Stockbrugger R, Russel M. Influence of quality of care on quality of life in
inflammatory bowel disease (IBD): literaturereview and studies planned.
Eur J Intern Med. 2000;11(4):228-234.
42. Russel MG. Changes in the incidence of inflammatory bowel disease: what does it
mean?
Eur J Intern Med. 2000;11(4):191-196.
43. Stockbrugger RW, Russel MG, van Blankenstein M, Shivananda S. EC-IBD: a European
effort in inflammatory bowel disease. Eur J Intern Med. 2000;11(4):187-190.
44. Geerling BJ, Badart-Smook A, van Deursen C, van Houwelingen AC, Russel MG,
Stockbrugger RW, Brummer RJ. Nutritional supplementation with N-3 fatty acids and
antioxidants in patients with Crohn's disease in remission: effects on antioxidant status
and fatty acid profile. Inflamm Bowel Dis. 2000;6(2):77-84.
45.: Geerling BJ, Dagnelie PC, Badart-Smook A, Russel MG, StockbruggerRW,
Brummer RJ. Diet as a risk factor for the development of ulcerative colitis. Am J
Gastroenterol. 2000;95(4):1008-13.
46. Russel MG, StockbruggerRW. Is appendectomy a causative factorin ulcerative colitis?
Eur J Gastroenterol Hepatol. 1998 ;10(6):455-7.
47. Russel MG, Volovics A, Schoon EJ, vanWijlick EH, Logan RF, Shivananda S,
Stockbrugger RW. Inflammatory bowel disease: is there any relation between smoking
status and disease presentation? European Collaborative IBD Study Group. Inflamm Bowel
Dis. 1998;4(3):182-6.
48. Russel MG, Engels LG, Muris JW, Limonard CB, Volovics A, BrummerRJ,
Stockbrugger RW. Modern life' in the epidemiology of inflammatory bowel disease: a case-
control study with special emphasis on nutritional factors. Eur J Gastroenterol Hepatol.
1998 Mar;10(3):243-9.
49. Russel MG, Dorant E, Volovics A, Brummer RJ, Pop P, Muris JW, Bos LP, Limonard CB,
Stockbrugger RW. High incidence of inflammatory bowel disease in The Netherlands:
results of a prospective study. The South Limburg IBD Study Group.Dis Colon Rectum.
1998;41(1):33-40.
50. Russel MG, Dorant E, Brummer RJ, van de Kruijs MA, Muris JW, BergersJM,
8. Goedhard J, Stockbrugger RW. Appendectomy and the risk of developing ulcerative colitis
or Crohn's disease: results of a large case-control study. South Limburg Inflammatory
Bowel Disease StudyGroup. Gastroenterology. 1997;113(2):377-82.
51. Russel MG, Pastoor CJ, Brandon S, Rijken J, Engels LG, vanderHeijde DM,
StockbruggerRW. Validation of the Dutch translation ofthe Inflammatory Bowel Disease
Questionnaire (IBDQ): a health-related quality of life questionnaire in inflammatory bowel
disease. Digestion. 1997;58(3):282-8.
52. Russel MG, Pastoor CJ, Janssen KM, vanDeursen CT, Muris JW, van Wijlick
EH, Stockbrugger RW. Familial aggregation of inflammatory bowel disease: a population-
based study in South Limburg, The Netherlands. The South Limburg IBD Study Group.
Scand J Gastroenterol Suppl. 1997;223:88-91.
53. Russel MG, Nieman FH, Bergers JM, Stockbrugger RW. Cigarette smoking and quality of
life in patients with inflammatory bowel disease. South Limburg IBD Study Group. Eur J
Gastroenterol Hepatol. 1996; 8(11):1075-81.
54. Russel MG, Stockbrugger RW. Epidemiology ofinflammatory bowel disease: an update.
Scand J Gastroenterol. 1996;31(5):417-27.
55. Russel MG, Zeijen RN, BrummerRJ, de BruineAP, van Kroonenburgh MJ,
Stockbrugger RW. Eosinophilic enterocolitis diagnosed by means of technetium-99m
albumin
scintigraphy and treated with budesonide (CIR). Gut. 1994;35(10):1490-2.
56. Russel MG, Lustermans FA, Wuite J, van Pelt J. Porphyria cutanea tarda in a patient
with AIDS. Neth J Med. 1992;41(1-2):68-70.
57. van Wersch JW, Russel MG, Lustermans FA.The extent of diffuse intravascular
coagulation and fibrinolysis in patients with liver cirrhosis. Eur J Clin Chem Clin Biochem.
1992;30(5):275-9.
Thesis
Incidence, risk factors and quality of life in IBD; Inflammatory Bowel Disease Registry
South Limburg, juli 1997, University of Maastricht.
Book contribution
Van Deventer SJH, Russel MG. Inflammatory Bowel Disease. In: Lanschot JJB, Gouma DJ,
Jansen PLM et al. Intergrated Medical and Surgical Gastroenterology. Bohn Stafleu Van
Loghum, 2004.