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This document discusses the pathophysiology and management of critical hyperglycemia in patients with type 2 diabetes mellitus. It covers the diagnostic criteria and differences between ketoacidosis and hyperosmolar hyperglycemic state. It also provides protocols for managing ketoacidosis and hyperosmolar hyperglycemic state based on guidelines from PERKENI, including continuous insulin therapy. Additionally, it discusses glucose targets for inpatients and prevention strategies, as well as glycemic control for outpatients.









