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COVID -19
Mouazama hanif
NO CONTENT
Intro of covid 19
Epidemiology
Structure of covid/anatomy
Pathogenesis and bio chemical
interaction
SAMPLE FOOTER TEXT 20XX 2
INTRODUCTION
Large family, found in human and
animals.
SARS(sever acute respiratory
syndrome)2002
MERS( middle east respiratory
syndrome)2012
COVID-19(coronavirus
infectious disease )
Virus is called the SARS cough
(SARS-Cov-2)
Spread/insertion
through bats--
pangolinseafood market-
human
7th known virus to infect human.
SAMPLE FOOTER TEXT 20XX 3
EPIDEMIOLOGY
24/5/202
5.27 million cases reported
Globally
15/march/2022
458million case
Death 6.04million
20XX 4
SAMPLE FOOTER TEXT 20XX 5
STRUCTURE OF COVID-19 (SARS COUGH )
Spike protein (allow the virus to attach the cell membrane to the host cells.
it contain a receptor.
Function.
Have subunit S1( bind to the host cell receptor)S2(mediate the fusion of the viral and cellular membranes).
M protein (membrane protein)
Define the shape of viral envelop,
central organizer
E protein (envelop protein)
This is smallest protein on viable surface.
Function
Integral in the assembly ,release virus from host cells and during replication
it is largely localized at the site of intracellular trafficking more specifically at the EPR,golgi apparatus.
Surface protein (nucleolus capsid)
Viral envelop (outer layer)fatty layer,
It will break with soap
Capsid (under beneath the nucleolus capsid ,
protein shell encloses the genetic material of the virus.
N protein (bound to the single strand of
RNA(dogmatic information)to allow to replicate.
Function (multifunctional )
Inhibit a lots of host cells defense mechanisms.
Assist viral RNA in replicating itself (new viral particle)
PATHOGENESIS
Spread mainly respiratory droplets(cough , sneeze)
Symptoms common cold stuffy nose headache sore throat and fever(5,6 days)
Mucosal epithelium of upper GI tract (primary replication occur)
Pathophysiology of covid-19
SPIKE PROTEIN Angiotensin converting enzyme 2(ACE2)
1)Lungs are the main target of SARS-cov-2
2)IL-1
3)TNFa
4)IL-6
5)Pyrogens
SAMPLE FOOTER TEXT 20XX 9
PATHOPHYSIOLOGY OF COVID-19
NUMA site (stop producing surfactant without surfactant the alveolar collapse and gas exchange is not
possible
Collection of fluid in the alveolar together
Alveolar cell damage
Alveolar inflammation
Alveolar collapse=ARDS
O2
20XX 10
SAMPLE FOOTER TEXT 20XX 11
SAMPLE FOOTER TEXT 20XX 12
Nutritional support
Immunity booster food like oranges
,ginger, garlic ,almonds
THANK YOU
Presenter name mouazama hanif
Email address
181460011@gift,edu.pk
SAMPLE FOOTER TEXT

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Covid 19 .

  • 2. NO CONTENT Intro of covid 19 Epidemiology Structure of covid/anatomy Pathogenesis and bio chemical interaction SAMPLE FOOTER TEXT 20XX 2
  • 3. INTRODUCTION Large family, found in human and animals. SARS(sever acute respiratory syndrome)2002 MERS( middle east respiratory syndrome)2012 COVID-19(coronavirus infectious disease ) Virus is called the SARS cough (SARS-Cov-2) Spread/insertion through bats-- pangolinseafood market- human 7th known virus to infect human. SAMPLE FOOTER TEXT 20XX 3
  • 4. EPIDEMIOLOGY 24/5/202 5.27 million cases reported Globally 15/march/2022 458million case Death 6.04million 20XX 4
  • 6. STRUCTURE OF COVID-19 (SARS COUGH ) Spike protein (allow the virus to attach the cell membrane to the host cells. it contain a receptor. Function. Have subunit S1( bind to the host cell receptor)S2(mediate the fusion of the viral and cellular membranes).
  • 7. M protein (membrane protein) Define the shape of viral envelop, central organizer E protein (envelop protein) This is smallest protein on viable surface. Function Integral in the assembly ,release virus from host cells and during replication it is largely localized at the site of intracellular trafficking more specifically at the EPR,golgi apparatus. Surface protein (nucleolus capsid) Viral envelop (outer layer)fatty layer, It will break with soap
  • 8. Capsid (under beneath the nucleolus capsid , protein shell encloses the genetic material of the virus. N protein (bound to the single strand of RNA(dogmatic information)to allow to replicate. Function (multifunctional ) Inhibit a lots of host cells defense mechanisms. Assist viral RNA in replicating itself (new viral particle)
  • 9. PATHOGENESIS Spread mainly respiratory droplets(cough , sneeze) Symptoms common cold stuffy nose headache sore throat and fever(5,6 days) Mucosal epithelium of upper GI tract (primary replication occur) Pathophysiology of covid-19 SPIKE PROTEIN Angiotensin converting enzyme 2(ACE2) 1)Lungs are the main target of SARS-cov-2 2)IL-1 3)TNFa 4)IL-6 5)Pyrogens SAMPLE FOOTER TEXT 20XX 9
  • 10. PATHOPHYSIOLOGY OF COVID-19 NUMA site (stop producing surfactant without surfactant the alveolar collapse and gas exchange is not possible Collection of fluid in the alveolar together Alveolar cell damage Alveolar inflammation Alveolar collapse=ARDS O2 20XX 10
  • 12. SAMPLE FOOTER TEXT 20XX 12 Nutritional support Immunity booster food like oranges ,ginger, garlic ,almonds
  • 13. THANK YOU Presenter name mouazama hanif Email address 181460011@gift,edu.pk SAMPLE FOOTER TEXT