3. Recap
Purpose: Assess the clinical results of lengthening the fourth
metatarsal in brachymetatarsia using three different surgical
techniques
Hypothesis: Unclear/Not Stated
Retrospective Study
153 feet, 106 pts ( 100 female, 6 males)
Mean age: 26.3 years (13-48)
4. Recap
Group 1: One-Stage Intercalary bone graft, secured by an IM K-Wire
(45 feet, 35 pts)
Group 2: Gradual lengthening with a Mini-External Fixator after
performing an Osteotomy with a saw (59 feet, 39 pts)
Group 3: Gradual lengthening using a Mini-external Fixator after an
Osteotomy with an Osteotome (49 feet, 32 pts)
6. Results
Table I: Details of patients in each group
• Note: “n” (sample size) is based on number of people
• Mean age in years proved significance in all three groups, based on p-value
• Patients with bilaterality did not prove significance.
• Number of females did not prove significance based on p-value
May be acceptable due to the epidemiology behind Brachymetatarsia
Brachymetatarsia is more common in females
Female:Male ratio is 25:1
7. Results
Table II: Pre-Operative Variables
Pre-op Percentage of the length of 4th metatarsal to the 2nd metatarsal - proved
significant
Pre-op Shortness of 4th toe - proved significant
Note: “n” (sample size) is based on number of feet
8. Results
Table III: Post-Operative Variables
Length gain for all three groups proved significance based on p-value
Length gain (%) was insignificant based on p-value
Percentage increase= lengthening obtained/ pre-operative length
Healing Index (wks/cm) was insignificant based on p-value
Fixation time for all three groups proved significance based on p-value
Note: 8 participants were disregarded due to failure of bone formation
9. Results
Table IV: Post-Operative Variables, based on AOFAS Score
AOFAS Score was insignificant based on p-value
Could be due to variance in pain tolerance levels in patients
AOFAS is based on Pain, Function, and Alignment
Subject Satisfaction score and Willingness was statistically significant
Note: All patients were considered for this data collection
10. Results – Pitfalls
Retrospective Study
Less control of variables
Sampling Bias
Hypothesis: Not stated
Mean age of pts: 26.3 years (Ranging from 13 to 48 years old)
Large range can lead to discrepancies in results of study (e.g., satisfaction survey and
overall healing time)
11. Results – Pitfalls
Study was not randomized
Selection bias
Patients were offered a choice of which treatment they wanted to
undergo
Researcher bias
Patient’s choice in treatment “may have been influenced by the
surgeon towards one-stage for pts with less shortening”
12. Results – Pitfalls
Sample size, “n,” was not consistent between the 4 tables
In Table 1, “n” represented number of patients
In Tables 2, 3, and 4, “n” represented number of feet
8 patients were disregarded in data collection post-operatively.
However, in the Table 4, which compared both pre-op and post-op
satisfaction and willingness to return, the 8 patients were taken
into consideration
Selection Bias
13. Results – Pitfalls
Discrepancy in metatarsal lengths between the groups
The preoperative length and length gain of the fourth metatarsal in the bone-graft
group were less short than those of the patients in other groups.
Technique of osteotomy in gradual lengthening was changed after
accumulating experience in the saw group
Leading to inconsistency
Compromises internal validity
Harmed patients prior to change in procedure
14. Results – Pitfalls
The pre-operative AOFAS score was 100 in all patients, and it was
reduced after surgery.
The main cause was pain at the plantar aspect of the proximal phalanx or
at the metatarsophalangeal joint after prolonged standing or walking and
decreased movement of this joint.
Despite this, the Willingness score was high (favorable)
Inconsistency in data
15. Results – Pitfalls
Mean Follow-Up: 22 months - ranging from 7 months to 55
months
Non-similar base-line measurements (range is too large)
AOFAS, Satisfaction score, and Willingness may have been affected
Recall bias may have occurs
17. Discussion
One-Stage Lengthening: Advantages
Advantages of One Stage Lengthening
Non requirement for a external fixator
No possibility of insufficient bone formation
No necessity for manipulation of the external fixator after
surgery
18. Discussion
One-Stage Lengthening: Disadvantages
Disadvantages of One Stage Lengthening
Limited lengthening
Immobilization of the MPJ during consolidation of the graft
Necessity for harvesting a bone graft
Allograft may lack capacity to heal
Maceration (most common problem of the plantar aspect of the MPJ, Due
to plantar slope of the met, the 4th toe is immobilized in a plantar-flexed
position promoting maceration)
19. Discussion
Gradual Lengthening – Advantages
Advantages of Gradual Lengthening
Ability to obtain greater length than one-stage
intercalary bone graft
Immediate weight-bearing can occur
Preservation of movement of the MPJ
Bone Osteotome reduces soft tissue damage
20. Discussion
Gradual Lengthening – Disadvantages
Disadvantage of Gradual Lengthening
Regular adjustment of the external fixator
Possibility of insufficient bone formation
Risk of pin-track infection
Micro-Saw method may cause local heat damage & necrosis
22. Non-specific to Surgical Tools
The Type and Model of the equipment used may cause
variance to the results.
Compromise the External Validity in achieving the same
results if the surgical techniques were repeated in a different
location.
Eg. Osteotome used in the Osteotomy was not specified.
25. Discussion
In the conclusion, the gradual lengthening method was re-stated as being the
most reliable.
However, in the Discussion section, only general references were made as to
the basic advantages of the method, which were not specific to the study.
Author explained many limitations:
Retrospective study
Selection bias for preferred lengthening by surgeon may have occurred
Technique in osteotomy was changed after accumulating experience in the saw group
26. Discussion – Pitfalls
Actual results were not discussed in this section
The Discussion section did not clearly match the Introduction in
comparing and concluding the most reliable result.
Overall, without a hypothesis, it is hard to compare the purpose of
the study with their conclusion.
28. Conclusion
In conclusion, the gradual lengthening by distraction osteogenesis
after osteotomy using an osteotome produces the most reliable
results for the treatment of fourth brachymetatarsia.
29. Conclusion – Pitfalls
Previously, research question was not clearly stated.
Hypothesis and null hypothesis was not stated.
Therefore, p-value credibility comes into question
p-value indicates whether or not there strong evidence against the null
hypothesis
Function of the p-value is to determine whether or not to reject the null
hypothesis
In this case, there is no hypothesis/null hypothesis to retain or reject
30. Conclusion – Pitfalls
Internal Validity was hindered due to multiple biases (as previously
mentioned)
External Validity
Tools and types of materials were not clearly stated
Study took place in Korea
Cultural differences may naturally occur
“distress felt by affected patients tends to be greater in Asian countries, where the feet are often
displayed indoors”
This may have skewed Satisfaction and Willingness survey
32. Summary
Future studies should be performed to overcome limitations due to:
Biases (Recall bias, Selection biases, and Researcher bias)
Prospective study would result in less confounding variables
Could not be generalized to all clinical settings
Some aspects of this study can be used for informative purposes, pre-operational
counseling, etc.
Ex. More rapid healing time in bone graft, longer lengthening in the distraction method,
higher satisfaction scores with the gradual distraction with osteotome
Overall, without a hypothesis and without clear evidence supporting this study’s
findings, it is hard to find this paper to be reliable
33. Resources
Baek, G., & Chung, M. (1998). The treatment of congenital brachymetatarsia by one-stage lengthening. The
Journal Of Bone And Joint Surgery, 1040-1044.
Choi, I., Chung, M., Baek, G., Cho, T., & Chung, C. (n.d.). Metatarsal Lengthening in Congenital
Brachymetatarsia: One-Stage Lengthening Versus Lengthening by Callotasis. Journal of Pediatric
Orthopaedics, 660-660.
Ferrandez, L., Yubero, J., Usabiaga, J., & Ramos, L. (1993). Congenital Brachymetatarsia: Three Cases. Foot &
Ankle International, 529-533.
Pasternack, W. (n.d.). Brachymetatarsia. A unique surgical approach. Journal of the American Podiatric
Medical Association, 415-418
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