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Percutaneous Transforaminal Endoscopic Discectomy in The Treat-
ment of Lumbar Disc Herniation: Effects on Early Rehabilitation
Original article
Abudourexiti ·Tuerhognjiang et al 9
Clin Surg Res Commun 2018; 2(2): 9 -13
Abudourexiti·Tuerhognjiang*, Rehaman·Sulaiman, Xiang-yu Meng, Liang Ma, Yun-tao Liu,
Chuan-yu He, Bing Liang
Abstract
Objective: The aim of this research was to evaluate the early rehabilitation and complications of percutaneous
transforaminal endoscopic discectomies (PTEDs) in the treatment of lumbar disc herniations.
Methods: From July 2015 to January 2017, ninety-one patients with lumbar disc herniations who underwent
PTEDs were retrospectively enrolled. During the six month follow-up period, a visual analogue scale (VAS)
and the Oswestry Disability Index (ODI) were used to evaluate the preoperative and postoperative (3 days, 3
months and 6 months) disturbance indexes. The Macnab criteria were used to evaluate the clinical efficacy.
The operation time, intraoperative blood loss, average length of the hospital stay, postoperative recurrence
rate, and complications were observed and recorded.
Result: The VAS and ODI scores for the lumbocrural pain after the surgery were significantly lower than those
before the surgery (p<0.05). There were no significant differences in the lower back pain VAS scores on the
postoperative 3rd day, 3rd month, and 6th month (p>0.05). The leg pain VAS score on the postoperative 3rd
day was significantly lower than that during the postoperative 3rd month (p<0.05). The lower back pain VAS
score during the postoperative 6th month was lower than that on the postoperative 3rd day, with no statistical
significance (p>0.05).
Conclusion: Based on the results of this study, PTEDs for the treatment of lumbar disc herniations are safe and
effective, with less trauma and complications. In addition, the postoperative rehabilitation time was markedly
shortened.
Keywords: percutaneous transforaminal endoscopic discectomy; lumbar disc herniation; visual analogue
scale; early rehabilitation
*Corresponding author: Abudourexiti·Tuerhognjiang
Mailing address: Department of Minimally Invasive Spine
Therapy, The Sixth Affiliated Hospital of Xinjiang Medical
University. Wuxingnan road no.39, Urumchi, Xinjiang, China.
E-mail: ta272@163.com
Received: 25 April 2018 Accepted: 26 June 2018
is widely used in a variety of lumbar degenerative dis-
eases and spinal infectious diseases, achieving a good
therapeutic effect [7,8]
. As a minimally invasive therapy, a
PTED has many remarkable advantages, such as a small
incision,lesssurgicalcomplications,shortlengthofstay,
safety, small economic burden, and rapid rehabilitation
[9,10]
. Therefore, it has been gradually accepted by more
and more surgeons and patients [11]
. From July 2015 to
January2017,ninety-onepatientswithlumbardischer-
niationsweretreatedwithPTEDsthatachievedsatisfac-
tory curative effects and rapid rehabilitation.
MATERIALS AND METHODS
General information
This retrospective study was approved by the Ethics
Committee of our hospital, and all of the patients signed
informed consent forms. From July 2015 through Jan-
uary 2017, a total of 91 patients with lumbar disc her-
niations, including 53 males and 38 females (19 to 80
years old, average age = 48.30±12.70 years) were se-
lected for this study. L4/5 disc herniations occurred in
INTRODUCTION
A lumbardischerniationisthe mostcommonspinal dis-
order, and it causes widespread medical problems [1,2]
.
The lumbar disc herniation incidence has been rising
with the aging population and the changes in the way
people work [3]
. Due to the degeneration of the lumbar
intervertebral disc, the fibrous circle is ruptured under
external force, which causes nucleus pulposus hernia-
tion, leading to peripheral nerve root compression and
waist symptoms, such as pain and numbness in the low-
er extremities [4,5]
.
A percutaneous transforaminal endoscopic discectomy
(PTED) is one effective surgery used for the treatment
of a lumbar disc herniation. It was originally used for
minimally invasive surgery [6]
, but nowadays, the PTED
Department of Minimally Invasive Spine Therapy, The Sixth Affiliated Hospital of Xinjiang Medical University. Urumchi, 830001, China.
Creative Commons 4.0
DOI: 10.31491/CSRC.2018.6.013
Abudourexiti ·Tuerhognjiang et al 10
Published online: 26 June 2018
ANT PUBLISHING CORPORATION
41 cases, L5/S1 disc herniations occurred in 48 cases,
and L3/4 disc herniations occurred in 2 cases. The sur-
geries were completed successfully, and the operation
time was 50–145 min, with an average time of 83.40
min. The intraoperative blood loss was 21–53 ml, with
anaveragebloodlossof35ml,andthelengthofstaywas
5–13 days, with an average time of 8 days. One patient
had cerebrospinal fluid leakage, without severe compli-
cations (such as nerve root injuries, abdominal organ
injuries, vascular injuries, and intervertebral disc space
infections). After the PTED, two cases underwent open
surgery due to recurrences, one case underwent open
surgery due to bone residue in the spinal canal, and the
rate of complications was 4.39%.
Inclusion criteria
From July 2015 to January 2017, those patients who
were admitted to our department and diagnosed with
single stage lumbar disc herniations who were willing
to undergo PTEDs were included in this study.
Exclusion criteria
The following patients were excluded from this study:
patients with multi-stage lumbar disc herniations,
lumbar scoliosis, lumbar disc spondylolisthesis, lumbar
spinal stenosis, spinal tuberculosis, spinal tumors,
soft tissue infections, a history of lumbar surgery,
and hyperparathyroidism. Those patients who took
hormone drugs over a long period of time were also
excluded.
Surgery
The patients who met the inclusion criteria underwent
lateral plain films of the lumbar vertebrae, computed
tomography (CT) plain film scanning of the lumbar
intervertebral discs, and magnetic resonance imaging
(MRI) scanning of the lumbar vertebrae. The history
and physical signs were considered in order to make a
definitive diagnosis. All of the patients received nucleus
pulposus resections under a transforaminal endoscope,
and they were treated with percutaneous endoscopic
lumbar discectomies (PELDs) using the transforaminal
endoscopic system (joimax GmbH, Karlsruhe, Germany)
and a bipolar radiofrequency scalpel (Trigger-Flex; el-
liquence, Baldwin, NY, USA).
Those patients with L3/4 and L4/L5 lumbar disc herni-
ations were placed in a prone position, the lumbar 4/5
disc space was determined via the positive perspective
oftheCarm,andthelineofthearticularprocessandjoint
was determined via the lateral perspective. Then, 12 cm
from the midline of the spinous process, at the lumbar
4/5 level, the puncture point was determined, with 1%
lidocaine used for the local anesthesia, and a Kirschner
needle was inserted to the upper margin of the L5. The
skin was cut approximately 0.8 cm at the puncture site,
an expansion chamber was inserted, and the working
channel was placed into the expansion chamber. The
microendoscope operating system and disposable neg-
ative pressure drainage tube were connected, and the
light was turned on. After inserting the transforaminal
endoscope through the working channel, the surround-
ing fat and ligamentum were removed using grasping
forceps, the nerve root was exposed, the protrusion of
the nucleus pulposus was removed, and the fibrous ring
was ablated via radiofrequency. After a full decompres-
sion,theworkingchannelwasremoved,andtheincision
was sutured.
General anesthesia was used for those patients with L5/
S1 disc herniations, and it was administered after effec-
tive anesthesia. The L5/S1 intervertebral space was de-
termined via the positive perspective of the C arm, and 2
cm from the midline of the affected side was determined
as the puncture point. The needle was inserted into the
medial part of the L5/S1 intervertebral space and the
Table 1. Comparison of preoperative VAS score and postoperative (3 days, 3 months and 6 months) VAS score.
postoperative 3 days postoperative 3 months postoperative 6 months
low back leg low back leg low back leg
Preoperative VAS score 4(3, 5) 7(6, 7) 4(3, 5) 7(6, 7) 4(3, 5) 7(6, 7)
Postoperative VAS score 1(0, 1) 1(1, 2) 1(0, 1) 1(1, 2) 1(0, 1) 1(1, 2)
Z value -8.22 -8.36 -8.20 -8.34 -8.12 -8.28
P value p<0.05 p<0.05 p<0.05 p<0.05 p<0.05 p<0.05
Table 2. Comparison of postoperative 3 days VAS score and postoperative 3 months and 6 months VAS score.
postoperative 3 months postoperative 6 months
low back leg low back leg
Postoperative 3 days VAS score 1(0, 1) 1(1, 2) 1(1, 2) 1(1, 2)
Postoperative (3 months, 6
months) VAS score
1(0, 1) 1(1, 2) 1(0, 1) 1(1, 2)
Z value -1.87 0 -1.82 -1.78
P value p>0.05 p>0.05 p>0.05 p>0.05
Abudourexiti ·Tuerhognjiang et al 11
Clin Surg Res Commun 2018; 2(2): 9 -13
lower edge of the left lamina. The remaining procedures
were the same as those administered after the local an-
esthesia .
Evaluation of curative effect
Allofthepatientswerefollowedupfor6months.Avisual
analogue scale (VAS) and the Oswestry Disability Index
(ODI)wereusedtoevaluatethepainseveritybeforesur-
gery, and 3 days, 3 months, and 6 months after surgery.
TheMacnabcriteriawereusedtoevaluatetheclinicalef-
ficacy 6 months after surgery: “excellent” indicated that
the symptoms and signs had completely disappeared,
andnormalactivitiesandworkwereresumed;“good”in-
dicated that the main symptoms and signs disappeared,
the patient could engage in their original work, and no
pain medication was required; “medium” indicated that
the symptoms and signs were obviously improved, but
they still affected work and life activities, and non-ste-
roidalanti-inflammatorydrugs(NSIADs)wererequired;
and“bad”indicatedthatthesymptomsandsignshadnot
improved or were even aggravated, and opioids were
required. One patient underwent a second operation
during the follow-up period.
Statistical analysis
We used the Statistical Package for the Social Sciences
version 17.0 for the data analysis. The measured data
were analyzed using normal testing and descriptive
analyses. If the data showed a normal distribution, they
were expressed as the mean ± standard deviation, and
they were analyzed using a paired sample t-test. If the
data did not show a normal distribution, they were ex-
pressed as the median and interquartile range, and they
were analyzed using a non-parametric Wilcoxon rank
sum test. P-values of less than 0.05 were considered to
be statistically significant.
RESULTS
Comparisons between the preoperative and postopera-
tive VAS scores
The postoperative (3-day, 3-month, and 6-month) VAS
scores for lower back pain were significantly lower than
those before surgery (Z=-8.22, -8.20, and -8.12, respec-
tively, p<0.05). Additionally, the postoperative (3-day,
3-month, and 6-month) VAS scores for leg pain were
significantly lower than those before surgery (Z=-8.36,
-8.34, and -8.28, respectively, p<0.05) (Table 1).
Comparisons among the postoperative VAS scores
The postoperative 3-month VAS score for lower back
pain was significantly lower than that of the postopera-
tive 3-day VAS score (Z=-1.87, p<0.05). However, there
was no significant difference between the postopera-
tive 3-month VAS score for leg pain and the postopera-
tive 3-day VAS score (Z=0, p>0.05). The postoperative
6-month VAS score for lower back pain was lower than
that of the postoperative 3-day VAS score, with no sta-
tistical significance (Z=-1.82, p>0.05). Moreover, there
wasnosignificantdifferencebetweenthepostoperative
6-month VAS score for leg pain and the postoperative
3-day VAS score (Z=-1.78, p>0.05) (Table 2).
Comparisons between the preoperative and postoper-
ative ODI scores
The postoperative 3-day ODI score was significantly
lower than that before surgery (t=20.52, p<0.05). In
addition, the postoperative 3-month ODI score was
significantly lower than that before surgery (t=27.18,
p<0.05). The postoperative 6-month ODI score was also
significantly lower than that before surgery (t=26.95,
p<0.05) (Table 3).
Comparisons among the postoperative ODI scores
The postoperative 3-month ODI score for leg pain was
significantly lower than the postoperative 3-day ODI
score(t=10.92,p<0.05).Thepostoperative6-monthODI
score for lower back pain was lower than the postop-
erative 3-day ODI score, with no statistical significance
(t=1.96, p>0.05) (Table 4).
Excellent rate of surgery
AccordingtotheMacnabcriteriascore,59cases(64.83%)
were excellent, 21 cases (23.08%) were good, 8 cases
Table 3. Comparison of preoperative ODI index and postoperative (3 days, 3 months and 6 months) ODI index.
postoperative 3 days postoperative 3 months postoperative 6 months
Preoperative ODI index 67.80±15.74 67.80±15.74 67.80±15.74
Postoperative ODI index 30.32±12.80 17.32±7.66 16.25±10.05
T value 20.52 27.18 26.95
P value p<0.05 p<0.05 p<0.05
Table 4. Comparison of postoperative 3 days ODI index
and postoperative 3 months and 6 months ODI index.
postoperative 3
days
postoperative 6
months
Postoperative 3
month ODI index
17.32±7.66 17.32±7.66
Postoperative 3 day
or 6 month ODI index
30.32±12.80 16.25±10.05
T value 10.92 1.96
P value p<0.05 p>0.05
DOI: 10.31491/CSRC.2018.6.013
Abudourexiti ·Tuerhognjiang et al 12
Published online: 26 June 2018
ANT PUBLISHING CORPORATION
the PTED, thus decreasing the ODI scores.
Many factors should be kept in mind during surgery,
such as the patient’s vital signs and radicular symptoms.
Water is the PTED medium, and the procedure can be
seen clearly with continuous washing; however, the wa-
terpressureshouldbeobserved.Toomuchpressureand
excessive time could lead to neck pain and discomfort
for the patient. The water temperature should not be
too cold, or it will increase the spinal cord response and
influencethesurgery.Inaddition,thepatient’stempera-
ture should be observed, because the incidence of hypo-
thermia is greater than 70% if the surgery time is more
than two hours. This can induce an emergency reaction,
reduce the patient’s immunity, increase the surgical
infection rate, and damage the coagulation mechanism
[19,20]
.
In conclusion, the use of PTEDs for the treatment of
lumbar disc herniations was safe and effective, with
less trauma, less tissue damage, and a rapid rehabilita-
tion time, which reduced the length of the hospital stay.
However, the tissue degeneration of the intervertebral
disc is obvious, the loss of intervertebral space is sig-
nificant, and the recurrence rate is high in patients un-
dergoing excessive nucleus pulposus and fibrous ring
removal during the surgery. Therefore, it is suggested
that the patient be cautious after surgery, and wear the
waist compression bandage for a longer period of time.
Weight bearing activities are forbidden for three to six
months, and functional exercise should be increased af-
ter the fiber ring crevasse is repaired.
CONFLICT OF INTEREST
None
ACKNOWLEDGEMENTS
This project was supported by Natural Science
Fund Project of Xinjiang uygur autonomous region
(No.2017D01C266).
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1–4. In this study, three cases underwent open surgery
duetopoorcurativeeffects.Oneofthemhadcerebrospi-
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nerve root, abdominal organ, and vascular injuries, and
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postoperativedaywasthesameasthatduring
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and 6th
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score was significantly lower than that before surgery,
and the postoperative 3-month ODI score was signif-
icantly lower than the postoperative 3-day ODI score.
However, there was no significant difference between
the postoperative 3-month and 6-month scores, which
might be related to the scoring items, such as lifting and
carrying things, a sedentary lifestyle, sexual activities,
and travel. However, the patients were required to rest
inbedandavoidsevereexerciseandsedentarinessafter
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DOI: 10.31491/CSRC.2018.6.013

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Percutaneous transforaminal endoscopic discectomy in the treatment of lumbar disc herniation

  • 1. Percutaneous Transforaminal Endoscopic Discectomy in The Treat- ment of Lumbar Disc Herniation: Effects on Early Rehabilitation Original article Abudourexiti ·Tuerhognjiang et al 9 Clin Surg Res Commun 2018; 2(2): 9 -13 Abudourexiti·Tuerhognjiang*, Rehaman·Sulaiman, Xiang-yu Meng, Liang Ma, Yun-tao Liu, Chuan-yu He, Bing Liang Abstract Objective: The aim of this research was to evaluate the early rehabilitation and complications of percutaneous transforaminal endoscopic discectomies (PTEDs) in the treatment of lumbar disc herniations. Methods: From July 2015 to January 2017, ninety-one patients with lumbar disc herniations who underwent PTEDs were retrospectively enrolled. During the six month follow-up period, a visual analogue scale (VAS) and the Oswestry Disability Index (ODI) were used to evaluate the preoperative and postoperative (3 days, 3 months and 6 months) disturbance indexes. The Macnab criteria were used to evaluate the clinical efficacy. The operation time, intraoperative blood loss, average length of the hospital stay, postoperative recurrence rate, and complications were observed and recorded. Result: The VAS and ODI scores for the lumbocrural pain after the surgery were significantly lower than those before the surgery (p<0.05). There were no significant differences in the lower back pain VAS scores on the postoperative 3rd day, 3rd month, and 6th month (p>0.05). The leg pain VAS score on the postoperative 3rd day was significantly lower than that during the postoperative 3rd month (p<0.05). The lower back pain VAS score during the postoperative 6th month was lower than that on the postoperative 3rd day, with no statistical significance (p>0.05). Conclusion: Based on the results of this study, PTEDs for the treatment of lumbar disc herniations are safe and effective, with less trauma and complications. In addition, the postoperative rehabilitation time was markedly shortened. Keywords: percutaneous transforaminal endoscopic discectomy; lumbar disc herniation; visual analogue scale; early rehabilitation *Corresponding author: Abudourexiti·Tuerhognjiang Mailing address: Department of Minimally Invasive Spine Therapy, The Sixth Affiliated Hospital of Xinjiang Medical University. Wuxingnan road no.39, Urumchi, Xinjiang, China. E-mail: ta272@163.com Received: 25 April 2018 Accepted: 26 June 2018 is widely used in a variety of lumbar degenerative dis- eases and spinal infectious diseases, achieving a good therapeutic effect [7,8] . As a minimally invasive therapy, a PTED has many remarkable advantages, such as a small incision,lesssurgicalcomplications,shortlengthofstay, safety, small economic burden, and rapid rehabilitation [9,10] . Therefore, it has been gradually accepted by more and more surgeons and patients [11] . From July 2015 to January2017,ninety-onepatientswithlumbardischer- niationsweretreatedwithPTEDsthatachievedsatisfac- tory curative effects and rapid rehabilitation. MATERIALS AND METHODS General information This retrospective study was approved by the Ethics Committee of our hospital, and all of the patients signed informed consent forms. From July 2015 through Jan- uary 2017, a total of 91 patients with lumbar disc her- niations, including 53 males and 38 females (19 to 80 years old, average age = 48.30±12.70 years) were se- lected for this study. L4/5 disc herniations occurred in INTRODUCTION A lumbardischerniationisthe mostcommonspinal dis- order, and it causes widespread medical problems [1,2] . The lumbar disc herniation incidence has been rising with the aging population and the changes in the way people work [3] . Due to the degeneration of the lumbar intervertebral disc, the fibrous circle is ruptured under external force, which causes nucleus pulposus hernia- tion, leading to peripheral nerve root compression and waist symptoms, such as pain and numbness in the low- er extremities [4,5] . A percutaneous transforaminal endoscopic discectomy (PTED) is one effective surgery used for the treatment of a lumbar disc herniation. It was originally used for minimally invasive surgery [6] , but nowadays, the PTED Department of Minimally Invasive Spine Therapy, The Sixth Affiliated Hospital of Xinjiang Medical University. Urumchi, 830001, China. Creative Commons 4.0 DOI: 10.31491/CSRC.2018.6.013
  • 2. Abudourexiti ·Tuerhognjiang et al 10 Published online: 26 June 2018 ANT PUBLISHING CORPORATION 41 cases, L5/S1 disc herniations occurred in 48 cases, and L3/4 disc herniations occurred in 2 cases. The sur- geries were completed successfully, and the operation time was 50–145 min, with an average time of 83.40 min. The intraoperative blood loss was 21–53 ml, with anaveragebloodlossof35ml,andthelengthofstaywas 5–13 days, with an average time of 8 days. One patient had cerebrospinal fluid leakage, without severe compli- cations (such as nerve root injuries, abdominal organ injuries, vascular injuries, and intervertebral disc space infections). After the PTED, two cases underwent open surgery due to recurrences, one case underwent open surgery due to bone residue in the spinal canal, and the rate of complications was 4.39%. Inclusion criteria From July 2015 to January 2017, those patients who were admitted to our department and diagnosed with single stage lumbar disc herniations who were willing to undergo PTEDs were included in this study. Exclusion criteria The following patients were excluded from this study: patients with multi-stage lumbar disc herniations, lumbar scoliosis, lumbar disc spondylolisthesis, lumbar spinal stenosis, spinal tuberculosis, spinal tumors, soft tissue infections, a history of lumbar surgery, and hyperparathyroidism. Those patients who took hormone drugs over a long period of time were also excluded. Surgery The patients who met the inclusion criteria underwent lateral plain films of the lumbar vertebrae, computed tomography (CT) plain film scanning of the lumbar intervertebral discs, and magnetic resonance imaging (MRI) scanning of the lumbar vertebrae. The history and physical signs were considered in order to make a definitive diagnosis. All of the patients received nucleus pulposus resections under a transforaminal endoscope, and they were treated with percutaneous endoscopic lumbar discectomies (PELDs) using the transforaminal endoscopic system (joimax GmbH, Karlsruhe, Germany) and a bipolar radiofrequency scalpel (Trigger-Flex; el- liquence, Baldwin, NY, USA). Those patients with L3/4 and L4/L5 lumbar disc herni- ations were placed in a prone position, the lumbar 4/5 disc space was determined via the positive perspective oftheCarm,andthelineofthearticularprocessandjoint was determined via the lateral perspective. Then, 12 cm from the midline of the spinous process, at the lumbar 4/5 level, the puncture point was determined, with 1% lidocaine used for the local anesthesia, and a Kirschner needle was inserted to the upper margin of the L5. The skin was cut approximately 0.8 cm at the puncture site, an expansion chamber was inserted, and the working channel was placed into the expansion chamber. The microendoscope operating system and disposable neg- ative pressure drainage tube were connected, and the light was turned on. After inserting the transforaminal endoscope through the working channel, the surround- ing fat and ligamentum were removed using grasping forceps, the nerve root was exposed, the protrusion of the nucleus pulposus was removed, and the fibrous ring was ablated via radiofrequency. After a full decompres- sion,theworkingchannelwasremoved,andtheincision was sutured. General anesthesia was used for those patients with L5/ S1 disc herniations, and it was administered after effec- tive anesthesia. The L5/S1 intervertebral space was de- termined via the positive perspective of the C arm, and 2 cm from the midline of the affected side was determined as the puncture point. The needle was inserted into the medial part of the L5/S1 intervertebral space and the Table 1. Comparison of preoperative VAS score and postoperative (3 days, 3 months and 6 months) VAS score. postoperative 3 days postoperative 3 months postoperative 6 months low back leg low back leg low back leg Preoperative VAS score 4(3, 5) 7(6, 7) 4(3, 5) 7(6, 7) 4(3, 5) 7(6, 7) Postoperative VAS score 1(0, 1) 1(1, 2) 1(0, 1) 1(1, 2) 1(0, 1) 1(1, 2) Z value -8.22 -8.36 -8.20 -8.34 -8.12 -8.28 P value p<0.05 p<0.05 p<0.05 p<0.05 p<0.05 p<0.05 Table 2. Comparison of postoperative 3 days VAS score and postoperative 3 months and 6 months VAS score. postoperative 3 months postoperative 6 months low back leg low back leg Postoperative 3 days VAS score 1(0, 1) 1(1, 2) 1(1, 2) 1(1, 2) Postoperative (3 months, 6 months) VAS score 1(0, 1) 1(1, 2) 1(0, 1) 1(1, 2) Z value -1.87 0 -1.82 -1.78 P value p>0.05 p>0.05 p>0.05 p>0.05
  • 3. Abudourexiti ·Tuerhognjiang et al 11 Clin Surg Res Commun 2018; 2(2): 9 -13 lower edge of the left lamina. The remaining procedures were the same as those administered after the local an- esthesia . Evaluation of curative effect Allofthepatientswerefollowedupfor6months.Avisual analogue scale (VAS) and the Oswestry Disability Index (ODI)wereusedtoevaluatethepainseveritybeforesur- gery, and 3 days, 3 months, and 6 months after surgery. TheMacnabcriteriawereusedtoevaluatetheclinicalef- ficacy 6 months after surgery: “excellent” indicated that the symptoms and signs had completely disappeared, andnormalactivitiesandworkwereresumed;“good”in- dicated that the main symptoms and signs disappeared, the patient could engage in their original work, and no pain medication was required; “medium” indicated that the symptoms and signs were obviously improved, but they still affected work and life activities, and non-ste- roidalanti-inflammatorydrugs(NSIADs)wererequired; and“bad”indicatedthatthesymptomsandsignshadnot improved or were even aggravated, and opioids were required. One patient underwent a second operation during the follow-up period. Statistical analysis We used the Statistical Package for the Social Sciences version 17.0 for the data analysis. The measured data were analyzed using normal testing and descriptive analyses. If the data showed a normal distribution, they were expressed as the mean ± standard deviation, and they were analyzed using a paired sample t-test. If the data did not show a normal distribution, they were ex- pressed as the median and interquartile range, and they were analyzed using a non-parametric Wilcoxon rank sum test. P-values of less than 0.05 were considered to be statistically significant. RESULTS Comparisons between the preoperative and postopera- tive VAS scores The postoperative (3-day, 3-month, and 6-month) VAS scores for lower back pain were significantly lower than those before surgery (Z=-8.22, -8.20, and -8.12, respec- tively, p<0.05). Additionally, the postoperative (3-day, 3-month, and 6-month) VAS scores for leg pain were significantly lower than those before surgery (Z=-8.36, -8.34, and -8.28, respectively, p<0.05) (Table 1). Comparisons among the postoperative VAS scores The postoperative 3-month VAS score for lower back pain was significantly lower than that of the postopera- tive 3-day VAS score (Z=-1.87, p<0.05). However, there was no significant difference between the postopera- tive 3-month VAS score for leg pain and the postopera- tive 3-day VAS score (Z=0, p>0.05). The postoperative 6-month VAS score for lower back pain was lower than that of the postoperative 3-day VAS score, with no sta- tistical significance (Z=-1.82, p>0.05). Moreover, there wasnosignificantdifferencebetweenthepostoperative 6-month VAS score for leg pain and the postoperative 3-day VAS score (Z=-1.78, p>0.05) (Table 2). Comparisons between the preoperative and postoper- ative ODI scores The postoperative 3-day ODI score was significantly lower than that before surgery (t=20.52, p<0.05). In addition, the postoperative 3-month ODI score was significantly lower than that before surgery (t=27.18, p<0.05). The postoperative 6-month ODI score was also significantly lower than that before surgery (t=26.95, p<0.05) (Table 3). Comparisons among the postoperative ODI scores The postoperative 3-month ODI score for leg pain was significantly lower than the postoperative 3-day ODI score(t=10.92,p<0.05).Thepostoperative6-monthODI score for lower back pain was lower than the postop- erative 3-day ODI score, with no statistical significance (t=1.96, p>0.05) (Table 4). Excellent rate of surgery AccordingtotheMacnabcriteriascore,59cases(64.83%) were excellent, 21 cases (23.08%) were good, 8 cases Table 3. Comparison of preoperative ODI index and postoperative (3 days, 3 months and 6 months) ODI index. postoperative 3 days postoperative 3 months postoperative 6 months Preoperative ODI index 67.80±15.74 67.80±15.74 67.80±15.74 Postoperative ODI index 30.32±12.80 17.32±7.66 16.25±10.05 T value 20.52 27.18 26.95 P value p<0.05 p<0.05 p<0.05 Table 4. Comparison of postoperative 3 days ODI index and postoperative 3 months and 6 months ODI index. postoperative 3 days postoperative 6 months Postoperative 3 month ODI index 17.32±7.66 17.32±7.66 Postoperative 3 day or 6 month ODI index 30.32±12.80 16.25±10.05 T value 10.92 1.96 P value p<0.05 p>0.05 DOI: 10.31491/CSRC.2018.6.013
  • 4. Abudourexiti ·Tuerhognjiang et al 12 Published online: 26 June 2018 ANT PUBLISHING CORPORATION the PTED, thus decreasing the ODI scores. Many factors should be kept in mind during surgery, such as the patient’s vital signs and radicular symptoms. Water is the PTED medium, and the procedure can be seen clearly with continuous washing; however, the wa- terpressureshouldbeobserved.Toomuchpressureand excessive time could lead to neck pain and discomfort for the patient. The water temperature should not be too cold, or it will increase the spinal cord response and influencethesurgery.Inaddition,thepatient’stempera- ture should be observed, because the incidence of hypo- thermia is greater than 70% if the surgery time is more than two hours. This can induce an emergency reaction, reduce the patient’s immunity, increase the surgical infection rate, and damage the coagulation mechanism [19,20] . In conclusion, the use of PTEDs for the treatment of lumbar disc herniations was safe and effective, with less trauma, less tissue damage, and a rapid rehabilita- tion time, which reduced the length of the hospital stay. However, the tissue degeneration of the intervertebral disc is obvious, the loss of intervertebral space is sig- nificant, and the recurrence rate is high in patients un- dergoing excessive nucleus pulposus and fibrous ring removal during the surgery. Therefore, it is suggested that the patient be cautious after surgery, and wear the waist compression bandage for a longer period of time. Weight bearing activities are forbidden for three to six months, and functional exercise should be increased af- ter the fiber ring crevasse is repaired. CONFLICT OF INTEREST None ACKNOWLEDGEMENTS This project was supported by Natural Science Fund Project of Xinjiang uygur autonomous region (No.2017D01C266). REFERENCES 1. Thaler, M., Lechner, R., Foedinger, B., Haid, C., Kavakebi, P., Galiano, K., and Obwegeser, A. (2015) Driving reaction time before and after surgery for disc herniation in patients with preoperative paresis. Spine J 15, 918-922 2. Choi,K.,Shim,H.,Hwang,J.,Shin,S.,Lee,D.,Jung,H.,Park,H., and Park, C. (2018) Comparison of surgical invasiveness betweenmicrodiscectomyandthreedifferentendoscopic discectomy techniques for lumbar disc herniation. World Neurosurg 3. Ma, D., Liang, Y., Wang, D., Liu, Z., Zhang, W., Ma, T., Zhang, L.,Lu,X.,andCai,Z.(2013)Trendoftheincidenceoflumbar disc herniation: decreasing with aging in the elderly. Clin Interv Aging 8, 1047-1050 4. Altinkaya,N.,andCekinmez,M.(2016)Lumbarmultifidus (8.79%) were medium, and 3 cases (3.30%) were bad. The total of the excellent and good rates combined was 87.91% DISCUSSION Alumbardischerniationisthemostcommonspinaldis- order,and68%ofthepatientsrecoverafternonsurgical treatment; however, conservative treatment does not workforallpatients,sosomemusthavethenucleuspul- posus removed via surgery [12] . In the past, decompres- sion with a total laminectomy or partial laminectomy using the lumbar posterior approach and open surgery were the standard treatments for the protrusion of a lumbar intervertebral disc. This type of surgery has a high success rate; however, there are also many disad- vantages, such as significant trauma, heavy bleeding, damage to the spinal structure, a long postoperative recovery time, and long-term side effects, including lower back and leg pain after surgery [13,14] . Due to the improvements in medicine and technology, more and more minimally invasive methods have appeared [15,16] . In recent years, the PTED has become widely used in the treatment of lumbar disc herniations, achieving a good effect [7] . After the nerve compression is cleared, the calcified intervertebral discs can undergo compres- sion therapy under a transforaminal endoscope [17,18] . Inthelasttwoyears,weappliedPTEDsinmanypatients with good results, which were better than those of open surgery.Thecomparisonsbetweenthepreoperativeand postoperative lumbar vertebrae are shown in Figures 1–4. In this study, three cases underwent open surgery duetopoorcurativeeffects.Oneofthemhadcerebrospi- nal fluid leakage without severe complications (such as nerve root, abdominal organ, and vascular injuries, and intervertebral disc-space infections). The complication rate was 4.39%, which was lower than the complication rateoftraditionalopensurgery(7%).Thepostoperative 3-dayVASscorewassignificantlylowerthanthatbefore surgery; however, there was no significant difference among the postoperative 3-day, 3-month, and 6-month VAS scores. Therefore, it can be said that the pain relief onthe3rd postoperativedaywasthesameasthatduring the 3rd and 6th postoperative months. The short-term curative effect was remarkable, and it allowed rapid rehabilitation. Moreover, the postoperative 3-day ODI score was significantly lower than that before surgery, and the postoperative 3-month ODI score was signif- icantly lower than the postoperative 3-day ODI score. However, there was no significant difference between the postoperative 3-month and 6-month scores, which might be related to the scoring items, such as lifting and carrying things, a sedentary lifestyle, sexual activities, and travel. However, the patients were required to rest inbedandavoidsevereexerciseandsedentarinessafter
  • 5. Abudourexiti ·Tuerhognjiang et al 13 Clin Surg Res Commun 2018; 2(2): 9 -13 musclechangesinunilaterallumbardischerniationusing magnetic resonance imaging. Skeletal Radiol. 45, 73-77 5. Strömqvist, F., Strömqvist, B., Jönsson, B., Gerdhem, P., and Karlsson, M. (2015) Outcome of surgical treatment of lumbar disc herniation in young individuals. Bone Joint J 97-B, 1675-1682 6. Henmi, T., Terai, T., Hibino, N., Yoshioka, S., Kondo, K., Goda, Y., Tezuka, F., and Sairyo, K. (2015) Percutaneous endoscopic lumbar discectomy utilizing ventral epiduroscopicobservationtechniqueandforaminoplasty for transligamentous extruded nucleus pulposus: technical note. J Neurosurg Spine, 1-6 7. Yang,S.,Chen,W.,Chen,H.,Kao,Y.,Yu,S.,andTu,Y.(2014) Extended indications of percutaneous endoscopic lavage and drainage for the treatment of lumbar infectious spondylitis. Eur Spine J 23, 846-853 8. Kim, H., Yudoyono, F., Paudel, B., Kim, K., Jang, J., Choi, J., Chung, S., Kim, J., Jang, I., Oh, S., Park, J., and Lee, S. (2018) Suprapedicular Circumferential Opening Technique of Percutaneous Endoscopic Transforaminal Lumbar Discectomy for High Grade Inferiorly Migrated Lumbar Disc Herniation. Biomed Res Int 2018, 5349680 9. Kondo,M.,Oshima,Y.,Inoue,H.,Takano,Y.,Inanami,H.,and Koga, H. (2018) Significance and pitfalls of percutaneous endoscopic lumbar discectomy for large central lumbar disc herniation. J Spine Surg 4, 79-85 10. Zhou, Y., Chen, G., Bi, D., and Chen, X. (2018) Short- term clinical efficacy of percutaneous transforaminal endoscopic discectomy in treating young patients with lumbar disc herniation. J Orthop Surg Res 13, 61 11. Tacconi, L., Baldo, S., Merci, G., and Serra, G. (2018) Transforaminal percutaneous endoscopic lumbar discectomy: outcome and complications in 270 cases. J Neurosurg Sci 12. Davis,N.,Hourigan,P.,andClarke,A.(2017)Transforaminal epidural steroid injection in lumbar spinal stenosis: an observational study with two-year follow-up. Br J Neurosurg 31, 205-208 13. Schwender, J., Holly, L., Rouben, D., and Foley, K. (2005) Minimally invasive transforaminal lumbar interbody fusion (TLIF): technical feasibility and initial results. J Spinal Disord Tech 18 Suppl, S1-6 14. Carilli, S., Oktenoglu, T., and Ozer, A. (2006) Open- window laparotomy during a transperitoneal approach to the lower lumbar vertebrae: new method for reducing complications. Minim Invasive Neurosurg 49, 227-229 15. Kamper, S., Ostelo, R., Rubinstein, S., Nellensteijn, J., Peul, W., Arts, M., and van Tulder, M. (2014) Minimally invasive surgery for lumbar disc herniation: a systematic review and meta-analysis. Eur Spine J 23, 1021-1043 16. Kogias, E., Franco Jimenez, P., Klingler, J., and Hubbe, U. (2015) Minimally invasive redo discectomy for recurrent lumbar disc herniations. J Clin Neurosci 22, 1382-1386 17. Gioffre', G., Impusino, A., and Tacconi, L. (2017) Retroperitoneal hematoma after minimally invasive lumbar discectomy: is the percutaneous endoscopic approach really safe? J Neurosurg Sci 18. Shiboi, R., Oshima, Y., Kaneko, T., Takano, Y., Inanami, H., and Koga, H. (2017) Different operative findings of cases predicted to be symptomatic discal pseudocysts after percutaneous endoscopic lumbar discectomy. J Spine Surg 3, 233-237 19. Bernard, H. (2013) Patient warming in surgery and the enhanced recovery. Br J Nurs 22, 319-320, 322-315 20. Munday, J., Hines, S., and Chang, A. (2013) Evidence utilisation project: Management of inadvertent perioperative hypothermia. The challenges of implementing best practice recommendations in the perioperative environment. Int J Evid Based Healthc 11, 305-311 DOI: 10.31491/CSRC.2018.6.013