Introduction and welcome to the opening by Dr. Kylie Thaler, Associate Director of the Austrian Cochrane Branch. Followed by a presentation by Sir Iain Chalmers on the James Lind Library initiative. December 14th, 2010, In Krems, Austria.
A Simple Rp- HPLC Method for Simultaneous Estimation of Six Cardiovascular Dr...iosrjce
A simple, convenient Rp-HPLC method has been developed and validated for the simultaneous
estimation of Metolazone, Indapamide, Nebivolol, Rosuvastatin, Olmesartan and Spironolactone. The column
used was an Inertsil ODS 3 V column of 250 mm length × 4.6 mm ID, with 3 micron particle size of adsorbent.
Separation was achieved using isocratic elution in a buffer-acetonitrile-methanol mobile phase at a flow rate of
1.2 ml/min. The detection was performed at wavelength of 225 nm using a UV detector. The column temperature
was 450C and injection volume was 20µl. The method was validated for precision, linearity and accuracy. The
% RSD for all the drugs was found to be less than 2 %. The correlation coefficient (r2
) was not less than 0.999
for all drugs. The mean percent recovery of the drugs from tablet placebo at 50%, 100% and 150% were within
limits. The marketed formulations of the drugs were analyzed and the mean assay results were found to be
within limits. The developed method can thus be employed for routine simultaneous analysis of Metolazone,
Indapamide, Nebivolol, Rosuvastatin, Olmesartan and Spironolactone in bulk and in their marketed
formulations
eparo - Neue Spielregeln (Vortrag bei der Working Products 2016)eparo GmbH
Keynote-Präsentation bei der Working Products Konferenz 2016.
Herausforderungen für Produktmanager bei der digitalen Produktentwicklung.
Die Probleme der Produktmanager sind keine Einzelfälle, sondern Zeichen eines größeren Umbruchs bei digitaler Innovation und Unternehmenskultur.
Es werden die verschiedenen Trends und Rahmenbedingungen aufgeführt, die digitale Produktentwicklung schwierig machen.
The Appraisal of Guidelines for Research and Evaluation (AGREE) Instrument evaluates the process of practice guideline development and the quality of reporting.
The original AGREE Instrument has been updated and methodologically refined. The AGREE II is now the new international tool for the assessment of practice guidelines. The AGREE II is both valid and reliable and comprises 23 items organized into the original 6 quality domains.
http://www.agreetrust.org/
PAT and QbD concepts in designing the LiMS and other Electronic systems in La...balakrishna t
tQmlab® is the premier management system for GxP operations and for supporting regulatory submissions. It delivers transformational productivity for QA/QC labs supporting customised workflows for quality control of drugs, stability testing, product release testing and post-release quality testing.
Introduction and welcome to the opening by Dr. Kylie Thaler, Associate Director of the Austrian Cochrane Branch. Followed by a presentation by Sir Iain Chalmers on the James Lind Library initiative. December 14th, 2010, In Krems, Austria.
A Simple Rp- HPLC Method for Simultaneous Estimation of Six Cardiovascular Dr...iosrjce
A simple, convenient Rp-HPLC method has been developed and validated for the simultaneous
estimation of Metolazone, Indapamide, Nebivolol, Rosuvastatin, Olmesartan and Spironolactone. The column
used was an Inertsil ODS 3 V column of 250 mm length × 4.6 mm ID, with 3 micron particle size of adsorbent.
Separation was achieved using isocratic elution in a buffer-acetonitrile-methanol mobile phase at a flow rate of
1.2 ml/min. The detection was performed at wavelength of 225 nm using a UV detector. The column temperature
was 450C and injection volume was 20µl. The method was validated for precision, linearity and accuracy. The
% RSD for all the drugs was found to be less than 2 %. The correlation coefficient (r2
) was not less than 0.999
for all drugs. The mean percent recovery of the drugs from tablet placebo at 50%, 100% and 150% were within
limits. The marketed formulations of the drugs were analyzed and the mean assay results were found to be
within limits. The developed method can thus be employed for routine simultaneous analysis of Metolazone,
Indapamide, Nebivolol, Rosuvastatin, Olmesartan and Spironolactone in bulk and in their marketed
formulations
eparo - Neue Spielregeln (Vortrag bei der Working Products 2016)eparo GmbH
Keynote-Präsentation bei der Working Products Konferenz 2016.
Herausforderungen für Produktmanager bei der digitalen Produktentwicklung.
Die Probleme der Produktmanager sind keine Einzelfälle, sondern Zeichen eines größeren Umbruchs bei digitaler Innovation und Unternehmenskultur.
Es werden die verschiedenen Trends und Rahmenbedingungen aufgeführt, die digitale Produktentwicklung schwierig machen.
The Appraisal of Guidelines for Research and Evaluation (AGREE) Instrument evaluates the process of practice guideline development and the quality of reporting.
The original AGREE Instrument has been updated and methodologically refined. The AGREE II is now the new international tool for the assessment of practice guidelines. The AGREE II is both valid and reliable and comprises 23 items organized into the original 6 quality domains.
http://www.agreetrust.org/
PAT and QbD concepts in designing the LiMS and other Electronic systems in La...balakrishna t
tQmlab® is the premier management system for GxP operations and for supporting regulatory submissions. It delivers transformational productivity for QA/QC labs supporting customised workflows for quality control of drugs, stability testing, product release testing and post-release quality testing.
Investigation of anthelmintic, anti inflammatory activity of leaves extract o...Gulzar Alam
ABSTRACT
From ancient time Acacia catechu Willd. (AC) is used as a potent medicinal. Preliminary phytochemical tests were conducted with the crude extract obtained
from the leaves of AC reveals the presence of carbohydrates, steroids, alkaloids, glycosides, tannins, saponins, flavones, and phenolic. Anthelmintic activity
of petroleum ether, ethanolic and ethanol:water (1:1) extracts of leaves of AC was evaluated by adult Indian earthworm, (Pheretima posthuma). The
anthelmintic activity of extract was compared with standard albendazole. Ethanol:water (1:1) extract was found to possess potent anthelmintic activity and
petroleum ether extract was found to be least active, while ethanol:water (1:1) extract playing an intermediate role. The anti-inflammatory activity of leaves
extracts at the doses of 300mg/kg body weight was investigated in albino rats of wiester strain using carrageenan induced rat paw oedema. The ethanol extract
of leaves showed significant anti- inflammatory activity (45%) when compared with the standard (54%). Further studies are suggested to isolate the active
principles which are responsible for the anthelmintic and anti-inflammatory activity.
Keywords: Acacia catechu Willd., Leaves extracts, Phytochemical tests, Anthelmintic & Anti-inflammatory activity,
Team-e Architectural Physical model Brochure Brenda Shaw
Team-E provide one stop services:
3D Rendering
3D Animation
Physical model
Multi-media
If you are interested, contact below:
Brenda Xiao
Email: teame05@teame.com.cn
Webinar 'Could you transform the way you do R&D in just 5 years?' - May 2014IDBS
Webinar presented by Dr Paul Denny-Gouldson,Vice President Solution Strategy, IDBS, on May 28, 2014
How you manage, deploy and purchase systems is set to change dramatically. Where do you stand?
It is estimated that more than 70% of software systems will be SaaS based or hosted – or both – within five years. While this has already and will continue to result in radical change, the potential benefits to your business drivers and strategic imperatives, such as internal and external collaboration, are undeniable.
Collaboration is increasingly becoming the mainstay of how organizations conduct their Research and Development (R&D). However, by its very nature, collaboration is a dynamic and can often be an unpredictable process.
To be beneficial, the IT and infrastructure that support your R&D collaborations must be equally dynamic and – above all – be simple to deliver to the network of collaborators as they are likely distributed around the globe and span multiple industry types from commercial to not-for-profit and academia.
The dramatic shift towards web-based deployment models for software seems set to continue. But they can only succeed if the software is simple, intuitive and requires little or no training for all types of users.
Electronic Laboratory Notebooks (ELNs) have a strong history and track record in delivering measurable business benefits in R&D collaborations, and now with changes in technologies, are even easier to deploy. Discover how the IDBS web-based ELN, E‑WorkBook Web, can deliver the right R&D collaboration solution for you.
This webinar is designed for those with an interest in improving collaboration, efficiency, and productivity in R&D and manufacturing across pharmaceuticals, biotechnology, chemicals, energy, engineering, food and beverage, and consumer goods.
By Juliane Ried 1, Gavin Stewart 2, David Hives 2, Martin Janczyk 3, Lorne Becker 4
1 Cochrane Innovations, Germany; 2 The Cochrane Library, Wiley, UK; 3 Cochrane Web Team, Germany; 4 Cochrane Innovations, USA
Investigation of anthelmintic, anti inflammatory activity of leaves extract o...Gulzar Alam
ABSTRACT
From ancient time Acacia catechu Willd. (AC) is used as a potent medicinal. Preliminary phytochemical tests were conducted with the crude extract obtained
from the leaves of AC reveals the presence of carbohydrates, steroids, alkaloids, glycosides, tannins, saponins, flavones, and phenolic. Anthelmintic activity
of petroleum ether, ethanolic and ethanol:water (1:1) extracts of leaves of AC was evaluated by adult Indian earthworm, (Pheretima posthuma). The
anthelmintic activity of extract was compared with standard albendazole. Ethanol:water (1:1) extract was found to possess potent anthelmintic activity and
petroleum ether extract was found to be least active, while ethanol:water (1:1) extract playing an intermediate role. The anti-inflammatory activity of leaves
extracts at the doses of 300mg/kg body weight was investigated in albino rats of wiester strain using carrageenan induced rat paw oedema. The ethanol extract
of leaves showed significant anti- inflammatory activity (45%) when compared with the standard (54%). Further studies are suggested to isolate the active
principles which are responsible for the anthelmintic and anti-inflammatory activity.
Keywords: Acacia catechu Willd., Leaves extracts, Phytochemical tests, Anthelmintic & Anti-inflammatory activity,
Team-e Architectural Physical model Brochure Brenda Shaw
Team-E provide one stop services:
3D Rendering
3D Animation
Physical model
Multi-media
If you are interested, contact below:
Brenda Xiao
Email: teame05@teame.com.cn
Webinar 'Could you transform the way you do R&D in just 5 years?' - May 2014IDBS
Webinar presented by Dr Paul Denny-Gouldson,Vice President Solution Strategy, IDBS, on May 28, 2014
How you manage, deploy and purchase systems is set to change dramatically. Where do you stand?
It is estimated that more than 70% of software systems will be SaaS based or hosted – or both – within five years. While this has already and will continue to result in radical change, the potential benefits to your business drivers and strategic imperatives, such as internal and external collaboration, are undeniable.
Collaboration is increasingly becoming the mainstay of how organizations conduct their Research and Development (R&D). However, by its very nature, collaboration is a dynamic and can often be an unpredictable process.
To be beneficial, the IT and infrastructure that support your R&D collaborations must be equally dynamic and – above all – be simple to deliver to the network of collaborators as they are likely distributed around the globe and span multiple industry types from commercial to not-for-profit and academia.
The dramatic shift towards web-based deployment models for software seems set to continue. But they can only succeed if the software is simple, intuitive and requires little or no training for all types of users.
Electronic Laboratory Notebooks (ELNs) have a strong history and track record in delivering measurable business benefits in R&D collaborations, and now with changes in technologies, are even easier to deploy. Discover how the IDBS web-based ELN, E‑WorkBook Web, can deliver the right R&D collaboration solution for you.
This webinar is designed for those with an interest in improving collaboration, efficiency, and productivity in R&D and manufacturing across pharmaceuticals, biotechnology, chemicals, energy, engineering, food and beverage, and consumer goods.
By Juliane Ried 1, Gavin Stewart 2, David Hives 2, Martin Janczyk 3, Lorne Becker 4
1 Cochrane Innovations, Germany; 2 The Cochrane Library, Wiley, UK; 3 Cochrane Web Team, Germany; 4 Cochrane Innovations, USA
Professor Marcus Müllner of the Austrian Agency for Health and Food Safety (AGES) presents "Does evidence-based decision making exist?" at the opening of the Austrian Cochrane Branch on December 14th, 2010 in Krems.
Professor Ruth Gilbert of University College London presents "Could a systematic review have prevented the epidemic of sudden infant death syndrome?" at the opening of the Austrian Cochrane Branch in Krems, Austria, on December 14th 2010.
Dr. Gerd Antes, Director of the German Cochrane Centre, presents "Evidenz ist essentiell - von der Idee zum globalen Netzwerk: Die Cochrane Collaboration".
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
The Gram stain is a fundamental technique in microbiology used to classify bacteria based on their cell wall structure. It provides a quick and simple method to distinguish between Gram-positive and Gram-negative bacteria, which have different susceptibilities to antibiotics
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
